Diagnostic Performance of Diastolic Hyperemia-Free Ratio Compared With Invasive Fractional Flow Reserve for Evaluation of Coronary Artery Disease
Percutaneous coronary intervention guided by invasive fractional flow reserve (FFR) improves cardiovascular outcomes compared with coronary angiography alone and compared with medical therapy in patients with stable ischemic heart disease.1,2 FFR-guided revascularization has been incorporated into American and European practice guidelines.3,4 However, the need for adenosine to achieve maximum hyperemia limits FFR because of patient discomfort, increased cost, increased procedural time, and variability in the time to achieve maximal hyperemia. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 16, 2024 Category: Cardiology Authors: Amit Vira, Dinu-Valentin Balanescu, Julie A. George, Simon R. Dixon, Ivan D. Hanson, Robert D. Safian Source Type: research
Don't Count On It: TIMI Frame Count Gets Left Behind in the Contemporary Era of Coronary Microvascular Dysfunction Assessment
During the early interventional cardiology era, more than a generation ago, a cohort of pioneering invasive cardiologists created a vast body of knowledge establishing the underpinnings of our understanding of Coronary Microvascular Disease (CMD) (1-3). Notably, there has been a recent resurgence of interest in invasive indices for the evaluation of coronary microvascular disease. This has occurred, in part, as a result of a growing need for the evaluation and treatment of patients with chest pain without large vessel CAD, and the development of new tools, including systems for dual analysis of CMD measures, Index of Micro...
Source: The American Journal of Cardiology - January 16, 2024 Category: Cardiology Authors: Waddah Malas, John J Lopez Tags: Editorial Source Type: research
COMPArison of Multi-Point Pacing and ConvenTional CRT Through Non-invasive Hemodynamics Measurement: Short and Long Term Results of the COMPACT-MPP Study
Invasive hemodynamic studies have demonstrated improved left ventricular (LV) performances when cardiac resynchronization therapy/defibrillator (CRT-D) is delivered through multi-point pacing (MPP). Nowadays, strategies that allow to study the same hemodynamic parameters at a non-invasive level have become available. The aim of the present study was to evaluate the clinical implication of using a patient-tailored approach for CRT programming based on non-invasively assessed LV hemodynamics to identify the best biventricular pacing modality between standard single-site pacing (STD) and MPP for each patient. (Source: The Ame...
Source: The American Journal of Cardiology - January 16, 2024 Category: Cardiology Authors: Francesco Passafaro, Antonio Rapacciuolo, Antonio Ruocco, Giuseppe Ammirati, Salvatore Crispo, Eugenia Pasceri, Giuseppe Santarpia, Ciro Mauro, Giovanni Esposito, Ciro Indolfi, Antonio Curcio Source Type: research
An Endovascular- Versus a Surgery-First Revascularization Strategy for Chronic Limb-Threatening Ischemia: A Meta-Analysis of Randomized Controlled Trials
Timely revascularization is essential for limb salvage and to reduce mortality in patients with chronic limb-threatening ischemia (CLTI). In patients who are candidates for endovascular therapy and surgical bypass, the optimal revascularization strategy remains uncertain. Recently published randomized controlled trials (RCTs) have presented conflicting results. We conducted a trial-level meta-analysis to compare the outcomes between endovascular-first and surgery-first strategies for revascularization. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Syed H. Mufarrih, Mohammad Saud Khan, Nada Qaisar Qureshi, Muhammad Shoaib Akbar, Mohammed Kazimuddin, Andrew M. Goldsweig, Philip P. Goodney, Herbert D. Aronow Source Type: research
Ohm My Goodness! Thoracic Impedance, Its Predictors, and How It Relates to Cardioversion
External electrical cardioversion is a mainstay treatment for acute rhythm control in patients with persistent atrial fibrillation (AF). While simple cardioversion without any specific preparation is commonly successful, in a significant minority of cases the initial attempt at cardioversion fails. In practice, usually, an initial failed shock is followed by further shocks, with or without modification to the method of shock delivery. The need to deliver additional shocks prolongs the procedure, requires a longer period of sedation, and involves some risk of proarrhythmia or other adverse effects including skin burns. (Sou...
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Daniel P. Morin, Joshua D. Aymond Tags: Editorial Source Type: research
Complete Revascularization Strategies in Women and Men With Acute Coronary Syndrome and Multivessel Disease
This prespecified substudy of the randomized BIOVASC trial aimed to compare immediate complete revascularization (ICR) and staged complete revascularization (SCR) in patients with acute coronary syndrome and multivessel disease, stratified by gender. The primary end point consisted of a composite of all-cause mortality, myocardial infarction, unplanned ischemia-driven revascularization, and cerebrovascular events at 1-year follow-up. The secondary end points included the individual components of the primary composite and major bleedings. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Jacob J. Elscot, Hala Kakar, Wijnand K. den Dekker, Johan Bennett, Manel Sabat é, Giovanni Esposito, Joost Daemen, Eric Boersma, Nicolas M. Van Mieghem, Roberto Diletti, BIOVASC investigators Source Type: research
Effects of Mask Wearing on Treadmill Exercise Test
A treadmill exercise stress test for cardiac physiologic responsiveness to stress at different levels of exercise is useful in identifying the presence of ischemic heart disease in patients with suspected coronary artery disease and determining the cardiopulmonary functional capacity. With the spread of COVID-19, the World Health Organization recommends wearing face masks to SARS-CoV-2 transmission. However, this measure could inevitably impact some medical diagnostic procedures, although evidence on the effects of face masks wearing during treadmill exercise tests remains limited. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Shao-Lun Ko, Chung-Lieh Hung, Chiao-Nan Chen, Tien-Ping Tsao, Man-Cai Fong, Wei-Hsian Yin, Hung-Yu Chang Tags: Brief Report Source Type: research
Smoking Cessation Is Associated With Short-Term Improvement of Vascular Health in a Cohort of People Living With HIV in Rio de Janeiro, Brazil
XX (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Rodrigo de Carvalho Moreira, Angela Rodrigues, Beatriz Menezes Leonardo, Daniel Arabe, Renata Santos, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdilea Veloso, Antonio G. Pacheco Source Type: research
Do Clinical Outcomes and Quality of Life Differ by the Number of Antianginals for Stable Ischemic Heart Disease? Insights from the BARI 2D Trial
Medical therapy, including antianginal treatment, is the cornerstone in the management of stable ischemic heart disease (SIHD). However, it remains unclear whether combining antianginal agents provides benefits beyond monotherapy in terms of quality of life (QoL) and cardiovascular outcomes. We used data from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial, which compared cardiovascular and QoL outcomes in patients with SIHD and diabetes mellitus randomized to revascularization with intensive medical therapy or intensive medical therapy alone. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Yasser Jamil, Dae Yong Park, Luis More Verde, Matthew W. Sherwood, Behnam N. Tehrani, Wayne B. Batchelor, Jennifer Frampton, Abdulla A. Damluji, Michael G. Nanna Source Type: research
Infective Endocarditis Complicated With a Large Left Coronary Cusp Aneurysm: A Condition With Undefined Natural History and Treatment
We describe herein the first case of a man aged 76 years with multiple co-morbidities with a NAV-IE associated large left coronary cusp aneurysm with subsequent rupture and consequent severe aortic regurgitation and heart failure for which he underwent an off-label successful TAVR. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Carlos A. Roldan, Kathleen Allen, Michelle Ratliff, Jerrold Grodin, Amer Alaiti, Subhash Banerjee Source Type: research
Minimalistic Hybrid Approach for the Percutaneous Treatment of Coronary Chronic Total Occlusions: Midterm Follow-Up of an International Multicenter Cohort
The progressive aging of the population and the increased survival of patients with complex coronary artery disease have a crucial role in the epidemiology of coronary chronic total occlusions (CTOs) that can be found in around 20% of patients who underwent coronary angiography.1 The success rates of CTO percutaneous coronary intervention (PCI) have favorably increased in the last decade with the evolution of techniques and the development of shared algorithms for standardized approach to CTO. Nowadays, in the hands of a dedicated expert operator, the success rate can reach over 90%. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Gianluca Castaldi, Mihajlo Kovacic, Enrico Poletti, Alice Benedetti, Alice Moroni, Benjamin Scott, Adriaan Wilgenhof, Andrea Bezzeccheri, Giovanni Vescovo, Simone Budassi, Hicham El Jattari, Carl Convens, Stefan Verheye, Paul Vermeersch, Carlo Zivelonghi, Source Type: research
Pilot Study of Supervised Exercise and Intensive Medical Therapy in Patients With Ischemia With No Evidence of Obstructive Coronary Artery Disease and Coronary Microvascular Dysfunction
Symptoms of ischemia with no evidence of obstructive coronary artery disease (INOCA) have a high prevalence and rate of major adverse cardiac events. We have previously identified a large symptom burden, physical limitation, substantial levels of cardiac anxiety, and significant economic impact in this population.1 Between 50% and 65% of patients with INOCA have coronary microvascular dysfunction (CMD) as identified by impaired myocardial perfusion reserve (MPR) on stress positron emission tomography or cardiac magnetic resonance (CMR) imaging. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Christopher L. Schumann, Zachariah B. Nealy, Roshin C. Mathew, Yang Yang, Pelbreton C. Balfour, Peter W. Shaw, Michael Salerno, Christopher M. Kramer, Jamieson M. Bourque Tags: Brief report Source Type: research
An endovascular- vs. a surgery-first revascularization strategy for chronic limb-threatening ischemia: A meta-analysis of randomized controlled trials
Timely revascularization is essential for limb salvage and to reduce mortality in patients with chronic limb-threatening ischemia (CLTI). In patients who are candidates for endovascular therapy and surgical bypass, the optimal revascularization strategy remains uncertain. Recently published randomized controlled trials (RCTs) have presented conflicting results. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Syed H. Mufarrih, Mohammad Saud Khan, Nada Qaisar Qureshi, Muhammad Shoaib Akbar, Mohammed Kazimuddin, Andrew M. Goldsweig, Philip P. Goodney, Herbert D. Aronow Source Type: research
Outcomes of Valve-In-Valve Transcatheter Aortic Valve Replacement
Structural valve degeneration (SVD) is increasingly seen given the higher rates of bioprosthetic heart valve (BHV) usage for surgical and transcatheter aortic valve replacement (TAVR). Valve-in-valve TAVR (VIV-TAVR) is an attractive alternate for patients who are otherwise at high risk for reoperative surgery. We compared patients undergoing VIV-TAVR and native-valve TAVR through a retrospective analysis of our institutional TVT database from 2013 to 2022. Patients undergoing either a native-valve TAVR or VIV-TAVR were included. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - January 15, 2024 Category: Cardiology Authors: Danial Ahmad, Sarah Yousef, Dustin Kliner, James A. Brown, Derek Serna-Gallegos, Catalin Toma, Amber Makani, David West, Yisi Wang, Floyd W. Thoma, Ibrahim Sultan Source Type: research
Coronary Flow Reserve and Myocardial Resistance Reserve Changes After Transcatheter Aortic Valve Implantation in Aortic Stenosis
Aortic valve stenosis (AS) induces an alteration in haemodynamic conditions that are responsible for coronary flow reserve (CFR) reduction and coronary microvasculature impairment. Consequently, despite presenting angiographically normal coronary arteries angina and ischemia may occur in some AS patients. 1-7 The effect of transcatheter aortic valve implantation (TAVI) on coronary haemodynamic in AS patients has not been completely clarified yet. Intracoronary continuous thermodilution is an operator-independent, adenosine-free and highly reproducible method, based on the principle of thermodilution. (Source: The American ...
Source: The American Journal of Cardiology - January 14, 2024 Category: Cardiology Authors: Alejandro Guti érrez-Barrios, Dolores Cañadas-Pruaño, Luis Martin Alfaro, Livia Gheorghe, Etelvino Silva MSC, Inmaculada Noval-Morillas, Carlos Campo-Cossio Pino, Ricardo Zayas Rueda, Germán Calle-Pérez, Rafael Vázquez-García, Rocio Toro-Cebada Source Type: research
