Subcutaneous versus Transvenous Implantable Defibrillators: a Systematic Review and Meta-Analysis
In patients with complex anatomy, high infection risk and venous access issues, subcutaneous implantable cardioverter-defibrillator (S-ICD) is presumed to be an appealing alternative to transvenous implantable cardioverter-defibrillator (T-ICD). T-ICD is known to cause perioperative and long-term complications. S-ICD does not offer anti-tachycardia pacing (ATP), back up pacing and chronic resynchronization therapy (CRT) but does have expanding indications. However, owing to0 ongoing uncertainty in efficacy and ambiguity in utility of S-ICD in low-risk patients, we performed this updated meta-analysis to study device relate...
Source: The American Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Maryam Saleem, Verda Arshad, Pooneh Nabavizadeh, Srinivas Rajsheker, Alexandru Costea Tags: Editorial Source Type: research

Impact of Age, Gender, and Body Mass Index on Short-Term Outcomes of Patients With Cardiogenic Shock on Mechanical Circulatory Support
This single-center, observational study assessed the impact of age, gender, and body mass index (BMI) in patients with cardiogenic shock (CS) on temporary mechanical circulatory support.All adult patients admitted to the Cleveland Clinic main campus Cardiac Intensive Care Unit (CICU) between December 1, 2015, to December 31, 2019, CICU with CS necessitating mechanical circulatory support (MCS) with intra-aortic balloon pump, Impella, or venous arterial-extra corporeal membrane oxygenation were retrospectively analyzed for this study. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Raunak M. Nair, Sachin Kumar, Talha Saleem, Ran Lee, Andrew Higgins, Umesh N. Khot, Grant W. Reed, Venu Menon Source Type: research

Racial Differences in Hospice Care Outcomes In Patients With Advanced Heart Failure: Systematic Review and Meta-analysis
There remains a paucity of investigational data about disparities in hospice services in people with non-cancer diagnoses, specifically in heart failure (HF). Black patients with advanced HF have been disproportionally affected by health care services inequities but their outcomes after hospice enrollment are not well studied. We aimed to describe race-specific outcomes in patients with advanced HF who were enrolled in hospice services. We obtained the data from PubMed, Scopus, and Embase for all investigations published until January 11, 2023 All studies that reported race-specific outcomes after hospice enrollment in pat...
Source: The American Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Diego Chambergo-Michilot, Victor G. Becerra-Gonzales, Veraprapas Kittipibul, Rosario Colombo, Katia Bravo-Jaimes Source Type: research

Racial Differences in Hospice Care Outcomes Among Patients with Advanced Heart Failure: Systematic Review and Meta-analysis
There remains a paucity of investigational data about disparities in hospice services among people with non-cancer diagnoses, specifically in heart failure. Black patients with advanced heart failure have been disproportionally affected by health care services inequities but their outcomes after hospice enrollment are not well studied. We aimed to describe race-specific outcomes in patients with advanced heart failure who were enrolled in hospice services. We obtained the data from PubMed, Scopus, and EMBASE for all investigations published until January 11th, 2023 All studies that reported race-specific outcomes after hos...
Source: The American Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Diego Chambergo-Michilot, Victor G Becerra-Gonzales, Veraprapas Kittipibul, Rosario Colombo, Katia Bravo-Jaimes Source Type: research

Impact of Age, Sex, and Body Mass Index on Short-Term Outcomes of Patients with Cardiogenic Shock on Mechanical Circulatory Support
This single-center observational study assessed the impact of age, sex, and body mass index (BMI) in patients with cardiogenic shock on temporary mechanical circulatory support. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Raunak M. Nair, Sachin Kumar, Talha Saleem, Ran Lee, Andrew Higgins, Umesh N. Khot, Grant W. Reed, Venu Menon Source Type: research

The Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Cardiovascular Outcomes in Patients With Cancer: A Systematic Review and Meta-Analysis
Clinical practice guidelines recommend the use of sodium-glucose cotransporter-2 inhibitors (SGLT-2i) to improve outcomes in patients with heart failure (HF).1,2 Patients receiving certain cancer therapies are at increased risk of developing HF, which is associated with worse health-related quality-of-life metrics and clinical outcomes.3 In patients receiving anthracyclines, the incidence of developing clinical HF can range from anywhere between 5% and 48%, depending on the cumulative anthracycline dose. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 17, 2024 Category: Cardiology Authors: Siddharth Agarwal, Usama Qamar, Yu Fujiwara, Avirup Guha, Abdul Rafeh Naqash, Eric H. Yang, Daniel Addison, Ana Barac, Zain Ul Abideen Asad Tags: Brief Report Source Type: research

Low Incidence of New Intracranial Aneurysms in Adults with Coarctation of Aorta on Serial Brain Imaging
Previous studies have reported are relatively high prevalence of intracranial saccular aneurysms in adults with coarctation of aorta (COA) with prevalence of around 10%.1-3 As a result, screening for intracranial aneurysms is routinely performed in adults with COA in some medical centers.1,2,4 In contrast to studies based on the adult COA population, a study conducted in pediatric patients with COA did not identify any case of intracranial aneurysm.5 Factors such as cigarette smoking, family history, connective tissue disorders, hypertension and age may influence the development of intracranial aneurysms, and in turn, coul...
Source: The American Journal of Cardiology - February 17, 2024 Category: Cardiology Authors: Alexander C. Egbe, William R. Miranda, C. Charles Jain, Luke J. Burchill, Maan Jokhadar, Robert D. Brown, Heidi M. Connolly Tags: Brief report Source Type: research

The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Cardiovascular Outcomes in Patients with Cancer: A Systematic Review and Meta-Analysis
Clinical practice guidelines recommend the use of sodium-glucose cotransporter-2 inhibitors (SGLT-2i) to improve outcomes in patients with heart failure (HF) (1-2). Patients receiving certain cancer therapies are at increased risk of developing HF, which is associated with worse health-related quality-of-life metrics and clinical outcomes (3). In patients receiving anthracyclines, the incidence of developing clinical HF can range from anywhere between 5% to 48% depending on the cumulative anthracycline dose (4). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 17, 2024 Category: Cardiology Authors: Siddharth Agarwal, Usama Qamar, Yu Fujiwara, Avirup Guha, Abdul Rafeh Naqash, Eric H. Yang, Daniel Addison, Ana Barac, Zain Ul Abideen Asad Tags: Brief report Source Type: research

Cardiovascular Health, Lifestyle Factors, and Social Determinants in Asian Subpopulations in the United States
Asian Americans are the fastest-growing population in the United States (US).1 Although Asian adults represent a highly heterogeneous population comprised of diverse groups (e.g., Chinese, Asian Indian, Filipino adults) — each with its own demographic, socioeconomic, and cultural characteristics—they are frequently categorized into a single group (“Asian”) for public health surveillance efforts.2,3 However, emerging evidence suggests that the aggregation of Asian adults may conceal important differences in the health status of unique groups that comprise this population. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 16, 2024 Category: Cardiology Authors: Sudheesha Perera, ZhaoNian Zheng, Rishi Wadhera Source Type: research

The End of a Controversy: The Rise, Fall, and Redemption of Paclitaxel-Coated Devices
Paclitaxel-coated devices (PCDs) for peripheral revascularization were initially considered one of the great success stories in endovascular treatment. Supported by more than a half dozen randomized trials, PCDs promised prolonged patency and decreased rates of target-lesion revascularization that had not been observed with non-coated devices.1,2 Once approved in the United States (US), PCDs became the most frequently used devices for femoropopliteal artery treatment and had a Class I indication in US guidelines. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 16, 2024 Category: Cardiology Authors: Eric A. Secemsky, Robert W. Yeh, Peter A. Schneider, William Gray, Sahil Parikh Tags: Editorial Source Type: research

Assessing the Role of Bempedoic Acid in Lipid-Lowering Therapy
We read with interest the study by Cordero et al. presenting their results1 of an intention-to-treat meta-analysis of the 4 CLEAR trials. Their study aims to consolidate the results of the CLEAR Outcomes trial. In that trial, bempedoic acid (BPA) proved to reduce a four-component major adverse cardiovascular event (MACE) endpoint, that included cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or coronary revascularization, as well as fatal and non-fatal MI and coronary revascularization. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 16, 2024 Category: Cardiology Authors: David Fernandez-Vazquez, Sarah Weideman, Subhash Banerjee Source Type: research

The End of a Controversy: The Rise, Fall and Redemption of Paclitaxel-Coated Devices
Paclitaxel-coated devices (PCDs) for peripheral revascularization were initially considered one of the great success stories in endovascular treatment. Supported by more than a half dozen randomized trials, PCDs promised prolonged patency and decreased rates of target-lesion revascularization that had not been observed with non-coated devices(1,2). Once approved in the US, PCDs became the most frequently used devices for femoropopliteal artery treatment and had a Class I indication in US guidelines(3-5). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 16, 2024 Category: Cardiology Authors: Eric A. Secemsky, Robert W. Yeh, Peter A. Schneider, William Gray, Sahil Parikh Tags: Editorial Source Type: research

Cardiovascular Health, Lifestyle Factors, and Social Determinants Among Asian Sub-Populations in the US
Asian Americans are the fastest growing population in the United States.1 Although Asian adults represent a highly heterogenous population comprised of diverse groups (e.g., Chinese, Asian Indian, Filipino adults) - each with its own demographic, socioeconomic, and cultural characteristics - they are frequently categorized into a single group ( “Asian”) for public health surveillance efforts.2,3 However, emerging evidence suggests that the aggregation of Asian adults may conceal important differences in the health status of unique groups that comprise this population. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 16, 2024 Category: Cardiology Authors: Sudheesha Perera, ZhaoNian Zheng, Rishi Wadhera Source Type: research

Corrigendum to ‘Effects of Diet on 10-Year Atherosclerotic Cardiovascular Disease Risk (from the DASH Trial)’ [American Journal of Cardiology 187 (2023) 10-17]
“The authors regret that the P-values accompanying Figure 2 were incorrect. During a recent review, the authors identified a potential inconsistency in their approach to using three-way interaction terms to test for differences across strata. In the original publication, the approach incorporated both the two-way and 3-way interaction terms. However, this was suboptimal, and a more direct comparison should focus on the P-value from the three-way interaction alone. While all the stratified results are correct, we revised the P-values to better reflect the comparison of the point estimates acr oss strata. (Source: The Amer...
Source: The American Journal of Cardiology - February 12, 2024 Category: Cardiology Authors: Sun Young Jeong, Christina C. Wee, Lara C. Kovell, Timothy B. Plante, Edgar R. Miller, Lawrence J. Appel, Kenneth J. Mukamal, Stephen P. Juraschek Tags: Corrigendum Source Type: research

Corrigendum to ’Effects of Diet on 10-Year Atherosclerotic Cardiovascular Disease Risk (from the DASH Trial)’ [American Journal of Cardiology 187 (2023) 10-17]
“The authors regret that the P-values accompanying Figure 2 were incorrect. During a recent review, the authors identified a potential inconsistency in their approach to using three-way interaction terms to test for differences across strata. In the original publication, the approach incorporated both the two-way and 3-way interaction terms. However, this was suboptimal, and a more direct comparison should focus on the P-value from the three-way interaction alone. While all the stratified results are correct, we revised the P-values to better reflect the comparison of the point estimates acr oss strata. (Source: The Amer...
Source: The American Journal of Cardiology - February 12, 2024 Category: Cardiology Authors: Sun Young Jeong, Christina C. Wee, Lara C. Kovell, Timothy B. Plante, Edgar R. Miller, Lawrence J. Appel, Kenneth J. Mukamal, Stephen P. Juraschek Tags: Corrigendum Source Type: research