Comparative Evaluation of Alcohol Septal Ablation: Left Anterior Descending Versus Nonleft Anterior Descending Artery Approaches
This study aimed to compare the effectiveness and safety between ASA performed using a septal branch arising from a non-LAD artery and a branch arising from the LAD artery. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Yoshihiro Harano, Yuki Sahashi, Yoshiaki Kawase, Hitoshi Matsuo Source Type: research
Comparative Evaluation of Alcohol Septal Ablation: Left Anterior Descending vs. Non-left Anterior Descending Artery Approaches
This study aimed to compare effectiveness and safety between ASA performed using a septal branch arising from a non-LAD artery and a branch arising from the LAD artery. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Yoshihiro Harano, Yuki Sahashi, Yoshiaki Kawase, Hitoshi Matsuo Source Type: research
Prognostic Impact of Previous Atherosclerotic Cardiovascular Disease on Short- and Long-Term Outcomes in Acute Myocardial Infarction
Patients with previous atherosclerotic cardiovascular disease (ASCVD) are typically managed by secondary prevention modalities, but they may experience recurrent events. In acute myocardial infarction (MI), the prognostic effect of pre-existing ASCVD on short- and long-term outcomes remains uncertain. This retrospective multicenter registry included 2475 patients with acute MI who had undergone percutaneous coronary intervention. Previous ASCVD was defined as a history of ischemic events in the coronary, cerebral, and peripheral arterial territories. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Yuichi Saito, Hiroaki Yaginuma, Kazunari Asada, Hiroki Goto, Takanori Sato, Hideki Kitahara, Yoshio Kobayashi Source Type: research
Cerebral Embolic Protection in Valve-in-Valve TAVR
In patients with degenerated aortic bioprosthesis, valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) has largely replaced the conventional reoperative surgical aortic valve replacement (SAVR).1 The Sentinel cerebral protection device (CPD) designed to capture and remove debris from the procedure received FDA approval in the USA in 2017 and is aimed at preventing post-procedural stroke.2 We analyze the impact of CPD use on outcomes of patients undergoing ViV-TAVR from a national, all-comers database. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Shashank Shekhar, Amar Krishnaswamy, Grant Reed, Rishi Puri, James Yun, Samir Kapadia Tags: Reader's Comments Source Type: research
Prolonged Dual Antiplatelet Therapy in Acute Myocardial Infarction Patients without Revascularization: China Acute Myocardial Infarction (CAMI) Registry Study
At least 12-month dual antiplatelet therapy (DAPT) is one of the standards of care following Percutaneous Coronary Intervention (PCI) in patients with acute coronary syndrome. However, study on prolonged DAPT for acute myocardial infarction (AMI) patients without revascularization is limited. We studied 1744 AMI patients without revascularization from the China Acute Myocardial Infarction registry between January 2013 and September 2014. These patients were on DAPT and did not experience AMI, stroke, or bleeding events at 12-month follow-up. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Cunrong Huang, Jingang Yang, Ling Li, Shenghu He, Xuxia Zhang, Haiyan Xu, Yuan Wu, Jun Zhang, Shubin Qiao, Yongjian Wu, Yanyan Zhao, Yang Wang, Wei Li, Chen Jin, Xiaojin Gao, Yuejin Yang, CAMI (China Acute Myocardial Infarction) Registry Study Group Source Type: research
How do the flow components of coronary flow reserve (CFR) change after aortic valve replacement?
To twist a lyric from the song “Dem [Dry] Bones”, we might summarize our purview as “valve bone connected to the heart bone” – technically the coupling between a stenotic aortic valve and myocardial function. In a practical sense, how does blood flow to the myocardium change in response to relief from severe aortic sten osis (AS)? The important contribution in this issue of the American Journal of Cardiology from investigators in Cádiz, Spain,1 provides new data to integrate into a unified hypothesis and help answer this question. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Rob Eerdekens, H.V. “Skip” Anderson, Nils P. Johnson Tags: Editorial Source Type: research
REGROUPing on the importance of complete revascularization in patients undergoing coronary artery bypass grafting
Complete revascularization (CR) is widely recognized as the goal of revascularization with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) for multivessel coronary disease. However, there has been limited robust prospective randomized data to support this objective, outside of patients with ST segment elevation myocardial infarction (STEMI). The data for revascularization of all anatomically significant non-culprit lesions after primary PCI of the culprit in STEMI patients is compelling. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Adebola Ogunsakin, J. Dawn Abbott Tags: Editorial Source Type: research
Sex-Related Outcomes of Transcatheter Aortic Valve Implantation with Self-Expanding or Balloon-Expandable Valves: Insights from the OPERA-TAVI Registry
This study sought to evaluate the impact of sex on the treatment effect of Evolut-PRO/PRO+ (PRO) or Sapien 3 Ultra (ULTRA) devices on clinical outcomes. Comparative Analysis of Evolut PRO vs Sapien 3 Ultra Valves for Transfemoral Transcatheter Aortic Valve Implantation (OPERA-TAVI) is a multicenter multinational registry including patients undergoing latest-iteration PRO or ULTRA implantation. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Marianna Adamo, Luca Branca, Elisa Pezzola, Francesco Saia, Thomas Pilgrim, Mohamed Abdel-Wahab, Philippe Garot, Caterina Gandolfo, Claudia Fiorina, Sofia Sammartino, Azeem Latib, Ignacio Amat Santos, Darren Mylotte, Federico De Marco, Ole De Backer, Luis Source Type: research
The Chronic Dilemma of Chronic Total Occlusion Revascularization
A chronic total occlusion (CTO) is encountered in up to 20% of patients with significant coronary artery disease (CAD) on coronary angiography and is a marker of advanced CAD and cardiovascular morbidity.(1) Several studies have evaluated surgical(2) and percutaneous revascularization in patients with CTO.(3) Percutaneous CTO revascularization of coronary vessels (CTO-PCI) remains a major challenge for interventional cardiologists, due to higher complexity, lower success rates and more frequent complications compared to revascularization of non-chronically occluded coronary vessels.(4) Notably, the last decade has witnesse...
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Salvatore Cassese, Adnan Kastrati Tags: Editorial Source Type: research
Classification of the Urgency of the Procedure and Outcome of Acute Type A Aortic Dissection
Surgery for type A aortic dissection (TAAD) is associated with high risk of early mortality. The prognostic impact of a new classification of the urgency of the procedure was evaluated in this multicenter cohort study.Data on consecutive patients who underwent surgery for acute TAAD were retrospectively collected in the multicenter, retrospective European Registry of TAAD (ERTAAD).The rates of in-hospital mortality of 3902 consecutive patients increased along with the ERTAAD procedure urgency grades: urgent procedure, 10.0%; emergency procedure grade 1, 13.3%; emergency procedure grade 2, 22.1%; salvage procedure grade 1, ...
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Fausto Biancari, Angelo M. Dell'Aquila, Francesco Onorati, Cecilia Rossetti, Till Demal, Andreas Rukosujew, Sven Peterss, Joscha Buech, Antonio Fiore, Thierry Folliguet, Andrea Perrotti, Am élie Hervé, Francesco Nappi, Lenard Conradi, Angel G. Pinto, Ja Source Type: research
Intracardiac Versus Transesophageal Echocardiography Guided Percutaneous Debulking of Tricuspid Endocarditis
There has been growing interest in percutaneous debulking for aspirating large right-sided valvular vegetations.1 This approach aims to achieve several objectives: debulking septic intracardiac masses, reducing the infectious burden, and establishing clinical stability, all while adopting a less invasive approach and avoiding surgical valve replacement. This is particularly valuable for this vulnerable cohort of patients who are more likely return to intravenous drug use with consequent risk of prosthetic valve endocarditis. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Robert S. Zhang, Eric Bailey, Muhammad H. Maqsood, Rafael Harari, Samuel Bernard, Yuhe Xia, Norma Keller, Carlos L. Alviar, Sripal Bangalore Tags: Brief report Source Type: research
Real-World Comparison of Clopidogrel with Ticagrelor and Prasugrel In Patients with Chronic Coronary Disease Undergoing Atherectomy
Current societal guidelines reserve potent P2Y12 platelet receptor inhibitors (ticagrelor, prasugrel) for acute coronary syndrome (ACS) cases due to a paucity of evidence for their use in chronic coronary disease (CCD).1 Patients with CCD undergoing percutaneous coronary intervention (PCI) with adjunctive atherectomy represent a subset of patients with more complex coronary disease who may derive benefit from more potent platelet inhibition.2 Atherectomy is associated with an increased risk of microvascular injury, endothelial dysfunction, and platelet activation, which may contribute to the increased risk of thrombosis, m...
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Mahin R. Khan, Anoop N. Koshy, Richard Tanner, Serdar Farhan, Manish Vinayak, Ali Farooq, Samantha Sartori, Yihan Feng, Alessandro Spirito, Ayush Arora, Vishal Dhulipala, Vishal Kapur, Javed Suleman, Raman Sharma, Roxana Mehran, Annapoorna Kini, Samin K. Tags: Brief report Source Type: research
Association of Myocardial Injury and Outcomes in Patients hospitalized with COVID-19
Coronavirus disease (COVID-19), caused by the outbreak of severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged as a major cause of morbidity and mortality globally.(1) Although, primarily a respiratory virus, symptoms of SARS-CoV-2 infection can be non-specific. Cardiovascular manifestations of COVID-19 are poorly understood but can include cardiac arrest, myocardial infarction (MI), arrhythmias, and myocarditis.(2) Myocardial injury in the form of troponin elevation is frequently seen in the clinical setting in hospitalized patients with COVID-19 and can range from demand ischemia to overt MI.(3) Through...
Source: The American Journal of Cardiology - February 22, 2024 Category: Cardiology Authors: Satyam Krishan, Khawaja Hassan Akhtar, Siddharth Agarwal, Jehanzeb Khan, Usman Baber Tags: Brief report Source Type: research
Subcutaneous versus Transvenous Implantable Defibrillators: a Systematic Review and Meta-Analysis
In patients with complex anatomy, high infection risk and venous access issues, subcutaneous implantable cardioverter-defibrillator (S-ICD) is presumed to be an appealing alternative to transvenous implantable cardioverter-defibrillator (T-ICD). T-ICD is known to cause perioperative and long-term complications. S-ICD does not offer anti-tachycardia pacing (ATP), back up pacing and chronic resynchronization therapy (CRT) but does have expanding indications. However, owing to0 ongoing uncertainty in efficacy and ambiguity in utility of S-ICD in low-risk patients, we performed this updated meta-analysis to study device relate...
Source: The American Journal of Cardiology - February 21, 2024 Category: Cardiology Authors: Maryam Saleem, Verda Arshad, Pooneh Nabavizadeh, Srinivas Rajsheker, Alexandru Costea Tags: Editorial Source Type: research
Impact of Age, Gender, and Body Mass Index on Short-Term Outcomes of Patients With Cardiogenic Shock on Mechanical Circulatory Support
This single-center, observational study assessed the impact of age, gender, and body mass index (BMI) in patients with cardiogenic shock (CS) on temporary mechanical circulatory support.All adult patients admitted to the Cleveland Clinic main campus Cardiac Intensive Care Unit (CICU) between December 1, 2015, to December 31, 2019, CICU with CS necessitating mechanical circulatory support (MCS) with intra-aortic balloon pump, Impella, or venous arterial-extra corporeal membrane oxygenation were retrospectively analyzed for this study. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - February 19, 2024 Category: Cardiology Authors: Raunak M. Nair, Sachin Kumar, Talha Saleem, Ran Lee, Andrew Higgins, Umesh N. Khot, Grant W. Reed, Venu Menon Source Type: research
