Disposable paper electrodes for detection of changes in dopamine concentrations in rat brain homogenates
Talanta. 2024 Mar 26;274:125940. doi: 10.1016/j.talanta.2024.125940. Online ahead of print.ABSTRACTDopamine, the main catecholamine neurotransmitter plays an important role in renal, cardiovascular, central nervous systems, and pathophysiological processes. The abnormal dopamine levels can result in neurological disorders such as Parkinson's, Alzheimer's, schizophrenia, acute anxiety, neuroblastoma and also contribute to cognitive dysfunctions. Given the widespread importance of dopamine concentration levels, it is imperative to develop sensors that are able to monitor dopamine. Herein, we have developed pre-anodized dispo...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: J Sonia B N Kumara Kevin Joakim Pinto A Hashim E S Sindhu Priya B Kalpana Renjtih Thomas K Sudhakara Prasad Source Type: research
Recent developments of (bio)-sensors for detection of main microbiological and non-biological pollutants in plastic bottled water samples: A critical review
Talanta. 2024 Mar 26;274:125962. doi: 10.1016/j.talanta.2024.125962. Online ahead of print.ABSTRACTThe importance of water in all biological processes is undeniable. Ensuring access to clean and safe drinking water is crucial for maintaining sustainable water resources. To elaborate, the consumption of water of inadequate quality can have a repercussion on human health. Furthermore, according to the instability of tap water quality, the consumption rate of bottled water is increasing every day at the global level. Although most people believe bottled water is safe, it can also be contaminated by microbiological or chemical...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Sofiene Mansouri Source Type: research
Sensitive and label-free SPR biosensing platforms for high-throughput screening of plasma membrane receptors interactions with insulin-like targets of hypoglycaemic activity
Talanta. 2024 Mar 26;274:125914. doi: 10.1016/j.talanta.2024.125914. Online ahead of print.ABSTRACTProgress in medical sciences aims for tailored therapy of civilization diseases like diabetes. Preclinical screening of new medicines superior to insulin should include the verification of their affinity to the membrane receptors naturally stimulated by this hormone: insulin receptor isoforms A and B and insulin-like growth factor receptor. Considering that the affinity constants obtained using different experimental conditions are incomparable, it is essential to develop a robust and reliable method to analyze these interact...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Marcin Drozd Ewa Kobylska Ma łgorzata Żmieńko Micha ł Chudy Source Type: research
Ag-modified CuO cavity arrays as a SERS-electrochemical dual signal platform for thiram detection
Talanta. 2024 Mar 23;274:125989. doi: 10.1016/j.talanta.2024.125989. Online ahead of print.ABSTRACTRapid and sensitive determination of pesticide residues in fruits and vegetables is critical for human health and ecosystems. This paper used an Ag-modified CuO sphere-cavity array (CuO@Ag) electrode as a thiram SERS/electrochemical dual readout detection platform. Numerous Raman "hotspots" generated by uniformly distributed silver nanoparticles, charge transfer at the CuO@Ag interface, and the formation of Ag-thiram complexes contribute to the significant enhancement of this SERS substrate, which results in excellent SERS pe...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Xinyi Shao Qun Zhao Jiayi Xia Mengxiang Xie Qingzhi Li Yuqi Tang Xuefang Gu Xiaofeng Ning Shanshan Geng Jin Fu Shu Tian Source Type: research
Detection of terminal deoxynucleotidyl transferase activity based on self-mediated nucleic acid elongation and elemental labeling inductively coupled plasma-mass spectrometry
Talanta. 2024 Mar 22;274:125979. doi: 10.1016/j.talanta.2024.125979. Online ahead of print.ABSTRACTTerminal deoxynucleotidyl transferase (TdT), a specialized DNA polymerase, is recognized as a promising biomarker for acute leukemia. Herein, taking the advantage of the self-mediated strand elongation property of TdT, a simple and sensitive method for TdT activity assay was developed based on gold nanoparticles (AuNPs) labeling inductively coupled plasma mass spectrometry (ICP-MS). In the presence of TdT, the primer DNA on magnetic beads is elongated with an adenine-rich single stranded long chain that can label poly-thymine...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Yuwei Liu Beibei Chen Man He Bin Hu Source Type: research
An array of femtoliter wells for sensitive detection of copper using click chemistry
In this study, we present a highly sensitive method for measuring Cu2+ in an array of femtoliter wells. In brief, magnetic beads (MBs) modified with alkyne groups were bound to the azide groups of biotin-PEG3-azide (bio-PEG-N3) via Cu+-catalyzed click chemistry. Cu+ in the click chemistry reaction was generated by reducing Cu2+ with sodium ascorbate. Following the ligation, the surface of the MBs was modified with biotin, which could be labeled with streptavidin-β-galactosidase (SβG). The MBs complex was then suspended in β-galactosidase substrate fluorescein-di-β-d-galactopyranoside (FDG), and loaded into the array of...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Chenchen Ge Xiong Chen Dou Wang Source Type: research
Confinement-enhanced electrochemiluminescence by Ru(dcbpy) < sub > 3 < /sub > < sup > 2+ < /sup > -functionalized γ-CD-MOF@COF-LZU1 porous hybrid material as micro-reactor for CYFRA 21-1 detection
Talanta. 2024 Mar 26;273:125959. doi: 10.1016/j.talanta.2024.125959. Online ahead of print.ABSTRACTThe improvement of electrochemiluminescence (ECL) performance relies on the electron transfer efficiency between luminophore and coreactant. An ultrasensitive ECL micro-reactor with confinement-enhanced performance was prepared by using the covalent organic framework-LZU1-functionalized metal-organic framework (MOF@COF-LZU1) as a platform to assemble enormous N,N-dibutyl-2-hydroxyethylamine (DBAE) and tris(4,4'-dicarboxylic acid-2,2'-bipyridyl) ruthenium(II) [Ru(dcbpy)32+] into its pore channels. Compared to individual substa...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: Xiang Ren Mingyue Shao Xiaofei Li Zuoxun Xie Jinxiu Zhao Huan Wang Min Gao Dan Wu Huangxian Ju Qin Wei Source Type: research
Kinetic detection of hydrogen peroxide in single horseradish peroxidase-concentrated silica particle using confocal fluorescence microspectroscopic measurement
Talanta. 2024 Mar 16;273:125925. doi: 10.1016/j.talanta.2024.125925. Online ahead of print.ABSTRACTIn the present study, we propose a scheme for detecting H2O2 by using horseradish peroxidase (HRP) adsorbed onto single silica particles and fluorescence microspectroscopy. When the silica particles were immersed in an HRP solution, the HRP concentration in the silica particles increased by a factor of 690 compared to that in the bulk aqueous solution because HRP was adsorbed on the silica surface. When a single particle containing HRP was added to a mixed solution of H2O2 and Amplex Red, fluorescence from resorufin, which wa...
Source: Talanta - March 25, 2024 Category: Chemistry Authors: Akihisa Miyagawa Kiyoharu Nakatani Source Type: research
Kinetic detection of hydrogen peroxide in single horseradish peroxidase-concentrated silica particle using confocal fluorescence microspectroscopic measurement
Talanta. 2024 Mar 16;273:125925. doi: 10.1016/j.talanta.2024.125925. Online ahead of print.ABSTRACTIn the present study, we propose a scheme for detecting H2O2 by using horseradish peroxidase (HRP) adsorbed onto single silica particles and fluorescence microspectroscopy. When the silica particles were immersed in an HRP solution, the HRP concentration in the silica particles increased by a factor of 690 compared to that in the bulk aqueous solution because HRP was adsorbed on the silica surface. When a single particle containing HRP was added to a mixed solution of H2O2 and Amplex Red, fluorescence from resorufin, which wa...
Source: Talanta - March 25, 2024 Category: Chemistry Authors: Akihisa Miyagawa Kiyoharu Nakatani Source Type: research
A magnetic graphene oxide and UiO-66 based homogeneous dual recognition electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1
Talanta. 2024 Mar 20;273:125915. doi: 10.1016/j.talanta.2024.125915. Online ahead of print.ABSTRACTAflatoxin (AFs) contamination is one of the serious food safety issues. Aflatoxin B1 (AFB1) is the most common and toxic aflatoxin, which has been classified as a class 1 carcinogen by the International Agency for Research on Cancer (IARC). It is extremely destructive to liver tissue. Developing a convenient and sensitive detection technique is essential. In this paper, we developed a homogeneous dual recognition strategy based electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1 (AFB1) based on the...
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Handong Yao Shuxin Du Liuhong Yang Yifeng Ding Hui Shen Yi Qiu Ge Dai Fengfeng Mo Source Type: research
Corrigendum to "Advancing mass spectrometry-based chemical imaging: A noncontact continuous flow surface probe in mass spectrometry for enhanced signal detection and spatial resolution" [Talanta 273 (2024) 125858]
Talanta. 2024 Mar 23;273:125929. doi: 10.1016/j.talanta.2024.125929. Online ahead of print.ABSTRACTIn the statement "This innovative MS imaging system can be directly applied to real tissue systems and other plant samples to visualize the molecular level distributions." "innovative" should be read as "important".PMID:38522189 | DOI:10.1016/j.talanta.2024.125929 (Source: Talanta)
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Abdil Ozdemir Jung-Lee Lin Mustafa Gulfen Chung-Hsuan Chen Source Type: research
A facile electrochemical immunosensor based on EDTA-Pb < sup > 2+ < /sup > complexation reaction
Talanta. 2024 Mar 19;273:125957. doi: 10.1016/j.talanta.2024.125957. Online ahead of print.ABSTRACTThe sensitivity of electrochemical (EC) sensors has been improved through the development of multiple approaches. However, the majority of EC sensors were limited in their practical application by high costs or tedious procedures. Herein, based on ethylenediaminetetraacetic acid (EDTA)-Pb2+ complexation reaction, a facile and affordable immunosensor was designed. Pb2+-magnesium silicate hydrate was served as the sensing substrate. The immunorecognition process was carried out in the Eppendorf tube, and antibody-functionalized...
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Shuli Zhang Ze Zhang Qichen Xiong Jiaqing Wang Hongliang Han Zhanfang Ma Source Type: research
Electrochemical detection of manganese ions using aptamer-based layers
Talanta. 2024 Mar 20;273:125926. doi: 10.1016/j.talanta.2024.125926. Online ahead of print.ABSTRACTHeavy metals are one of the major pollutants found in drinking water and their abnormal level may pose a threat to human's health and life. Manganese also belongs to heavy metals group, and it is generally used in production of batteries, fertilizers, and ceramics. Even though, Mn is necessary for proper development of central nervous system, its elevated concentration might lead to certain diseases such as epilepsies, cell death in focal cerebral ischemia as well as neurodegenerative diseases such as Huntington and Alzheimer...
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Marta Jarczewska Magdalena Borowska Marcin Olszewski Elzbieta Malinowska Source Type: research
A magnetic graphene oxide and UiO-66 based homogeneous dual recognition electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1
Talanta. 2024 Mar 20;273:125915. doi: 10.1016/j.talanta.2024.125915. Online ahead of print.ABSTRACTAflatoxin (AFs) contamination is one of the serious food safety issues. Aflatoxin B1 (AFB1) is the most common and toxic aflatoxin, which has been classified as a class 1 carcinogen by the International Agency for Research on Cancer (IARC). It is extremely destructive to liver tissue. Developing a convenient and sensitive detection technique is essential. In this paper, we developed a homogeneous dual recognition strategy based electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1 (AFB1) based on the...
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Handong Yao Shuxin Du Liuhong Yang Yifeng Ding Hui Shen Yi Qiu Ge Dai Fengfeng Mo Source Type: research
Corrigendum to "Advancing mass spectrometry-based chemical imaging: A noncontact continuous flow surface probe in mass spectrometry for enhanced signal detection and spatial resolution" [Talanta 273 (2024) 125858]
Talanta. 2024 Mar 23;273:125929. doi: 10.1016/j.talanta.2024.125929. Online ahead of print.ABSTRACTIn the statement "This innovative MS imaging system can be directly applied to real tissue systems and other plant samples to visualize the molecular level distributions." "innovative" should be read as "important".PMID:38522189 | DOI:10.1016/j.talanta.2024.125929 (Source: Talanta)
Source: Talanta - March 24, 2024 Category: Chemistry Authors: Abdil Ozdemir Jung-Lee Lin Mustafa Gulfen Chung-Hsuan Chen Source Type: research
