Using clustering as pre-processing in the framework of signal unmixing for exhaustive exploration of archaeological artefacts in Raman imaging
Talanta. 2024 Mar 26;274:125955. doi: 10.1016/j.talanta.2024.125955. Online ahead of print.ABSTRACTAnalytical chemistry on archaeological material is an essential part of modern archaeological investigations and from year to year, instrumental improvement has made it possible to generate data at a high spatial and temporal frequency. In particular, Raman spectral imaging can be successfully applied in archaeological research by its simplicity of implementation to study past human societies through the analysis of their material remains. This technique makes it possible to simultaneously obtain spatial and spectral informat...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Marc Offroy Mario Marchetti Thomas H Kauffmann Patrice Bourson Ludovic Duponchel Laurent Savarese Jean-Michel Mechling Source Type: research
Two-dimensional photonic crystal sensor enabled by hydrophobic hydrogen-bonded organic Frameworks@Metal-Organic frameworks for trace nerve agents detection
Talanta. 2024 Mar 27;274:125974. doi: 10.1016/j.talanta.2024.125974. Online ahead of print.ABSTRACTThe development of fast and accurate sensors for nerve agents holds immense significance for homeland security and public health. However, the humidity interference from ambient environments and poor sensitivity for trace nerve agents are largely unsolved problems. To overcome the problems, a humidity-independent two-dimensional photonic crystal (2-D PC) sensor is developed by exploiting UiO-66-NH2 2-D PC with excellent sensitivity coupled to a hydrophobic hydrogen-bonded organic framework (HOFs) for detection sarin simulant ...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Zhaolong Wang Yaru Wang Yangfan Gao Jun Yan Yunlin Chen Source Type: research
Boronate crosslinking-based ratiometric electrochemical assay of glycated albumin
Talanta. 2024 Mar 25;274:125990. doi: 10.1016/j.talanta.2024.125990. Online ahead of print.ABSTRACTAs a product of nonenzymatic glycation, glycated albumin (GA) is a promising serum marker for the short-term glycemic monitoring in patients with diabetes. On the basis of the boronate crosslinking (BCL)-enabled direct labeling of ferrocene (Fc) tags to the nonenzymatically glycated (NEG) sites, we report herein a novel aptamer-based ratiometric electrochemical (apt-REC) platform for the point-of-care (POC) assay of GA. This apt-REC platform is based on the recognition of GA proteins by the methylene blue (MB)-modified aptame...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Jianwen Wan Shiqi Li Yingming Ma Qiong Hu Yiyi Liang Zhiwen Liang Wenxing Feng Yiyan Tian Mingru Hong Zhuojun Ye Dongxue Han Li Niu Source Type: research
High-throughput BCRP inhibitors screening system based on styrene maleic acid polymer membrane protein stabilization strategy and surface plasmon resonance biosensor
Talanta. 2024 Mar 23;274:125987. doi: 10.1016/j.talanta.2024.125987. Online ahead of print.ABSTRACTMultidrug resistance (MDR) is a dominant challenge in cancer chemotherapy failure. The over-expression of breast cancer resistance protein (BCRP) in tumorous cells, along with its extensive substrate profile, is a leading cause of tumor MDR. Herein, on the basis of styrene maleic acid (SMA) polymer membrane protein stabilization strategy and surface plasmon resonance (SPR) biosensor, a novel high-throughput screening (HTS) system for BCRP inhibitors has been established. Firstly, LLC-PK1 and LLC-PK1/BCRP cell membranes were c...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Jiahao Fang Shuqi Shen Hui Wang Yuzhen He Liang Chao Yan Cao Xiaofei Chen Zhenyu Zhu Zhanying Hong Yifeng Chai Source Type: research
Organic photoelectrochemical transistor based on cascaded DNA network structure modulated ZnIn < sub > 2 < /sub > S < sub > 4 < /sub > /MXene Schottky junction for sensitive ATP detection
In this study, the DNA network formed by the hybridization chain reaction (HCR) detects the target adenosine triphosphate (ATP) by adjusting the surface potential of the new heterojunction of ZnIn2S4/MXene. The formation of DNA network amplifies the detection signal of ATP. Significantly, OPECT biosensor could further amplify the signal, which calculated the gain achieved 103, which is consistent with the gain signal of the previously reported OPECT biosensor. Furthermore, the OPECT biosensor achieved a highly sensitivity detection of the target ATP, which the linear detection range is 0.03 pM-30 nM, and the detection limi...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Xiaodi Wu Jiayi Cui Qihao Sun Xue Wang Jiahe Chen Yue Liu Jia-Hao Chen Degang Jiang Zhongmin Zhou Hong Zhou Source Type: research
WS < sub > 2 < /sub > nanosheets-based electrochemical biosensor for highly sensitive detection of tumor marker miRNA-4484
Talanta. 2024 Mar 27;274:125965. doi: 10.1016/j.talanta.2024.125965. Online ahead of print.ABSTRACTIn this paper, a few-layer WS2 nanosheets-based electrochemical biosensor was fabricated for the highly sensitive detection of breast cancer tumor marker miRNA-4484. Firstly, few-layer WS2 nanosheets were prepared by shear stripping and characterized by SEM, TEM, AFM and UV spectrophotometer. After modification of few-layer WS2 nanosheets on the electrode surface, the miRNA probe was fixed on the few-layer WS2 nanosheets by polycytosine (PolyC). Then short-chain miRNA containing PolyC was used as the blocking agent to close t...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Dujuan Li Huyue Wei Rui Hong Xiaojie Yue Linxi Dong Kai Fan Jing Yu Defei Yao Hong Xu Jun Lu Gaofeng Wang Source Type: research
Colorimetric detection of circulating tumor cells in breast cancer based on ladder-branch hybridization chain reaction and DFs/AuNCs nanozyme
Talanta. 2024 Mar 28;274:125921. doi: 10.1016/j.talanta.2024.125921. Online ahead of print.ABSTRACTBreast cancer is the most common malignant tumor in women, which accounts for 6.9% of all cancer-related deaths. Early diagnosis is crucial for making the best clinical decision and improving the prognosis of patients. Circulating tumor cells (CTCs) have been regarded as significant tumor biomarkers. Herein, we designed a colorimetric biosensor for breast cancer CTCs quantification based on ladder-branch hybridization chain reaction (HCR) and DNA flowers/gold nanoclusters (DFs/AuNCs) nanozyme. With the assistance of complemen...
Source: Talanta - March 29, 2024 Category: Chemistry Authors: Dongxia Ren Hua Wei Na Li Wenda Fu Zhijun Huang Longfei Yang Shijie Mu Source Type: research
Electrochemical genosensor based on RNA-responsive human telomeric G-quadruplex DNA: A proof-of-concept with SARS-CoV-2 RNA
In this report, a facile and label-free electrochemical RNA biosensor is developed by exploiting methylene blue (MB) as an electroactive positive ligand of G-quadruplex. The electrochemical response mechanism of the nucleic acid assay was based on the change in differential pulse voltammetry (DPV) signal of adsorbed MB on the immobilized human telomeric G-quadruplex DNA with a loop that is complementary to the target RNA. Hybridization between synthetic positive control RNA and G-quadruplex DNA probe on the transducer platform rendered a conformational change of G-quadruplex to double-stranded DNA (dsDNA), and increased th...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Nadiah Ibrahim Kok Beng Gan Nurul Yuziana Mohd Yusof Choo Ta Goh Niranjana Krupa B Ling Ling Tan Source Type: research
Acceptor-donor-acceptor type organic photothermal agents with enhanced NIR absorption and photothermal conversion effect for cancer photothermal therapy
Talanta. 2024 Mar 27;274:125991. doi: 10.1016/j.talanta.2024.125991. Online ahead of print.ABSTRACTNumerous photothermal agents (PTAs) require high-intensity and long-duration laser excitation for photothermal therapy (PTT), resulting in light damage to healthy skin and tissue as well as limiting their biomedical applications. Integrating desirable near-infrared (NIR) absorption and high photothermal conversion efficiency (PCE) into a single small-molecule PTA is an important prerequisite for realizing efficient PTT, but is a serious challenge. Herein, through molecular engineering strategy, an acceptor-donor-acceptor (A-D...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Mengxin Sun Xilin Zhao Xiaohan Cao Xiaoyu Li Jiashuai Xu Xiangtai Meng Hongguang Lu Xiaowei Zhao Source Type: research
A non-targeting magnetic metal-organic framework probe for highly specific peptide-mediated precise disease monitoring
Talanta. 2024 Mar 19;274:125948. doi: 10.1016/j.talanta.2024.125948. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a universal neurodegenerative disease in older adults with incurable and progressive properties, urging for precise monitoring to perform timely treatment to delay its progression. Herein, we introduced a non-targeting magnetic metal-organic framework probe coupled with high-throughput mass spectrometry, creating a rapid screening strategy for highly specific peptides associated with AD. Notably, an elution-free extraction process was proposed, significantly reducing sample preprocessing time while...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Wantong Zhang Zixing Xu Xiangmin Zhang Yinghua Yan Chunhui Deng Nianrong Sun Source Type: research
Determination of Fe, Cu, and Pb in edible oils using choline chloride:ethylene glycol deep eutectic solvent-based dispersive liquid-liquid microextraction associated with microwave-induced plasma optical emission spectrometry
Talanta. 2024 Mar 26;274:125939. doi: 10.1016/j.talanta.2024.125939. Online ahead of print.ABSTRACTA new simple, fast and environmentally friendly deep eutectic solvent based dispersive liquid-liquid microextraction (DES-based DLLME) methodology assisted by vortex is presented for the separation and preconcentration of three elements (i.e., Fe, Cu and Pb) from edible oil samples (i.e., soybean, sunflower, rapeseed, sesame, and olive oil) prior to the determination by microwave-induced plasma optical emission spectrometry (MIP-OES). The deep eutectic solvent selected as extractant (i.e., choline chloride and ethylene glycol...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Cristina Zapater Miguel Ángel Aguirre Nerea Gonz ález-Gallardo Diego J Ram ón Lorena Vidal Antonio Canals Source Type: research
A three-dimensional hierarchical porous graphene aerogel as a fiber coating for headspace solid-phase microextraction: Enhancing the enrichment and detection of polychlorinated naphthalenes in fish
In this study, a novel three-dimensional hierarchical porous deep eutectic solvents-modified graphene aerogel (3D DES-GA) was synthesized for use as a solid-phase microextraction (SPME) fiber coating. The SPME fiber was characterized by its fluffy and hierarchical porous structure, uniform thickness, and rapid mass transfer capabilities. This fiber demonstrated a lifetime (≥160 uses) and excellent precision (with relative standard deviations of 2.4-6.6% for single fiber and 6.0-9.8% for fiber-to-fiber repeatability). The SPME fiber also exhibited remarkable extraction performance for polycyclic aromatic hydrocarbons and ...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Pengfei Li Zhiqiang Wang Dandan Han Yehong Han Hongyuan Yan Source Type: research
Intelligent color image analysis of sintered ores for simple and rapid determination of Fe < sub > 3 < /sub > O < sub > 4 < /sub > concentration
Talanta. 2024 Mar 22;274:125985. doi: 10.1016/j.talanta.2024.125985. Online ahead of print.ABSTRACTA simple determination of the Fe3O4 concentrations of sintered ores using color images of the samples has been explored. Sintered ore is mainly composed of Fe2O3 (red), Fe3O4 (black), and other white inorganic oxides, so the color of sintered ore could be representative of the relative abundance of the constituents. Two important challenges were addressed to achieve reliable quantitative color image analysis. First, minute dents and bumps (embosses) exist on the sample surface due to inconsistent particle sizes and particle a...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Seongsoo Jeong Haeseong Jeong Seung Jee Yang Sanghoon Cho Hoeil Chung Source Type: research
Nanomaterials-based electrochemical biosensors for diagnosis of COVID-19
Talanta. 2024 Mar 26;274:125994. doi: 10.1016/j.talanta.2024.125994. Online ahead of print.ABSTRACTSince the outbreak of corona virus disease 2019 (COVID-19), this pandemic has caused severe death and infection worldwide. Owing to its strong infectivity, long incubation period, and nonspecific symptoms, the early diagnosis is essential to reduce risk of the severe illness. The electrochemical biosensor, as a fast and sensitive technique for quantitative analysis of body fluids, has been widely studied to diagnose different biomarkers caused at different infective stages of COVID-19 virus (SARS-CoV-2). Recently, many report...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Xinxin Liu Yifan Sun Huaiyu Song Wei Zhang Tao Liu Zhenyu Chu Xiaoping Gu Zhengliang Ma Wanqin Jin Source Type: research
A nanozyme with switchable enzyme-like activity for the logic gates detection of thymol and hydrogen peroxide in honey
Talanta. 2024 Mar 27;274:125951. doi: 10.1016/j.talanta.2024.125951. Online ahead of print.ABSTRACTA new nanozyme (CuGaa) with switchable enzyme-like activity of peroxidase and polyphenol oxidase was successfully prepared based on guanidinoacetic acid and copper. The two enzyme-like activities can be easily switched by changing temperature or adding MnCl2. At 4 °C, polyphenol oxidase-like activity decreased to nearly 1%, and the material is mainly characterized by peroxidase-like activity at this point. However, at 60 °C in the presence of 20 mM MnCl2, the peroxidase-like activity decreased to nearly 10%, and the polyphe...
Source: Talanta - March 28, 2024 Category: Chemistry Authors: Jie Li Luwei Wang Donghui Song Yongxin Li Hui Huang Source Type: research
