The impact of prenatal group B streptococcus screening as a national health policy in Taiwan
There was no national data on group B streptococcus (GBS) infections in Taiwan. Until 2012, when prenatal GBS screening was introduced to obstetric practices as a national health policy aimed at reducing neonatal GBS infections. The purpose of this study was to examine the impact of this national health policy on the incidence of maternal GBS colonization and neonatal GBS infection rate. Relatedly, the clinical characteristics of neonatal GBS infection were investigated to determine the correlations between the incidence of maternal GBS colonization and the neonatal GBS infection rate. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Fung-Wei Chang, Chun-I Lee, Hueng-Chuen Fan, Her-Young Su, Yung-Liang Liu, Cheng-Yu Chen Tags: Original Article Source Type: research

Association of miR-146a rs2910164 and miR-222 rs2858060 polymorphisms with the risk of polycystic ovary syndrome in Iranian women: A case –control study
Today, many single nucleotide polymorphisms in microRNA genes are known to alter the microRNA expression levels or processing causing susceptibility of several human diseases. The present study aimed to investigate the association of microRNA-146a (rs2910164) and microRNA-222 (rs2858060) polymorphisms with susceptibility to polycystic ovary syndrome (PCOS) in an Iranian population. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Amir Hossein Hosseini, Leila Kohan, Azita Aledavood, Sara Rostami Tags: Original Article Source Type: research

The role of resveratrol on full – Thickness uterine wound healing in rats
In this study, we aimed to investigate the effects of resveratrol (3,5,4 ′-o-trihydroxystilbene) on the wound healing process of the uterus in rats treated with resveratrol following full thickness injury of the uterus. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Oya Sayin, Serap Cilaker Micili, Asli Goker, Gonca Kamaci, Bekir Ugur Ergur, Osman Yilmaz, Gul Guner Akdogan Tags: Original Article Source Type: research

A genome-wide comparison of mesenchymal stem cells derived from human placenta and umbilical cord
In this study, we compared the genome-wide expression data of umbilical cord and placenta derived hMSCs to identify specific differential expression genes (DEGs) and corresponding functions. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Sen-Wen Teng, Yu-Shu Lo, Wei-Ting Liu, Yogi Hsuan, Willie Lin Tags: Original Article Source Type: research

Transcutaneous electrical acupoint stimulation (TEAS) treatment improves pregnancy rate and implantation rate in patients with implantation failure
Although major advances have greatly improved the outcomes of assisted reproductive technology in the last two cascades, there remains significant difficulty in achieving pregnancy for many patients even after repeated attempts of IVF. Interestingly, recent studies have shown that transcutaneous electrical acupoint stimulation (TEAS) can improve the reproductive outcomes of select IVF patients. To determine the utility of TEAS in improving IVF outcomes in patients with a history of implantation failure, we conducted a retrospective study of clinical outcomes of women, who had a prior history of unsuccessful pregnancy outco...
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Ya-Chiung Hsu, I-Ting Liang, Shang-Yu Huang, Hsin-Shih Wang, Yung-Kuei Soong, Chia-Lin Chang Tags: Original Article Source Type: research

Prenatal diagnosis of isochromosome 20q in a fetus with vertebral anomaly and rocker-bottom feet
We describe a new prenatal case of i(20q) with fetal malformations. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Aline Receveur, Sophie Brisset, Jelena Martinovic, Anne Bazin, Laurence Lhomann, Claire Colmant, Dominique Pineau, Val érie Gautier, Lucie Tosca, Gérard Tachdjian Tags: Short Communication Source Type: research

Monozygotic twins discordant for trisomy 21: Discussion of etiological events involved
To elucidate the etiologies of discordant trisomy 21 in monozygotic twin pregnancy. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Yao-Lung Chang, Wu-Pei Yi, An-Shine Chao, Kuan-Ju Chen, Po-Jen Cheng, Tzu-Hao Wang, Shuenn-Dyh Chang Tags: Case Report Source Type: research

Noninvasive prenatal diagnosis for X-linked disease by maternal plasma sequencing in a family of Hemophilia B
To apply a Hidden Markov Model to test Hemophilia B in a fetus by maternal plasma sequencing only employing proband and maternal haplotypes. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Ping Hu, Fengchang Qiao, Yuan Yuan, Ruihong Sun, Yan Wang, Lulu Meng, Ying Lin, Hang Li, Yaoshen Wang, Rui Han, Dong Liang, Dingyuan Ma, Tao Jiang, Hui Jiang, Zhengfeng Xu Tags: Case Report Source Type: research

Repeated pregnancy with concomitant presence of ovarian teratoma: A case report and literature review
Benign mature teratoma during pregnancy is common, mostly discovered incidentally by antenatal sonography. However, repeated pregnancy coincident with ovarian mature teratoma is rarely reported. The cases of teratoma with rapid growing characteristics are even more unique. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Liang-Hsuan Chen, Shuenn-Dhy Chang, Hong-Yuan Huang, Hsin-Shih Wang, Yung-Kuei Soong, Hsien-Ming Wu Tags: Case Report Source Type: research

Dandy –Walker syndrome with duplex kidney abnormalities in trisomy 18 – A rare case report
Trisomy 18 is one of the major numerical chromosomal disorders. The incidence of trisomy 18 is approximately one in 6000 live births. Dandy –Walker malformation (DWM) is the most common congenital malformation of the cerebellum, with an incidence of about one in 5000 live births. The incidence of trisomy 18 associated with DWM is rare and long-term survival rate is very low. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Tun-Jun Wang, Yi-Ying Li, Wan-Ju Wu, Chi-Kang Lin, Chun-Kai Wang, Chen-Yu Wang, Kwei-Shuai Hwang, Her-Young Su Tags: Case Report Source Type: research

Management of pregnancy in pancreas alone transplant recipient complicated with stage-4 chronic renal insufficiency and superimposed pre-eclampsia: Case report and literature review
With the prolonged life expectancy in solid organ transplant recipients, their quality of life and fertility desire become of particular concern. Pregnancy in pancreas-alone transplantation, although rare and complicated to manage, is not impossible anymore. We here report such a case with literature review to address this issue. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Yung-Shih Lee, Mei-Yu Peng, Chin-Ru Ker, Te-Fu Chan Tags: Case Report Source Type: research

Perspective of Taiwan's experience in the management of meconium peritonitis
Meconium peritonitis, a rare condition with an incidence of 1 in 30,000 births, is an aseptic chemical peritonitis resulting from intrauterine bowel perforation, associated with significant neonatal risk with morbidity and mortality [1]. Based on our search of PubMed (1970 –May 2017; search terms: “meconium peritonitis,” “Taiwan”; https://www.ncbi.nlm.nih.gov/pubmed/?term=meconium+peritonitis%2C+Taiwan), there are a few cases of fetal meconium peritonitis available in Taiwan [2–16]. To share the Taiwan's experience in the management of meconium peritonitis , we would like to report one new case and update this ...
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Yu-San Lin, Chang-Ching Yeh, Wen-Hsun Chang, I-San Chan, Chi-Yao Lin, Peng-Hui Wang Tags: Correspondence Source Type: research

Granulosa cell tumor of ovary: Perspective of Taiwan
A 6-month-old girl presented to our institution with intermittent vaginal bleeding for two months. After careful examination, neither trauma nor foreign body was noted. Laboratory examination revealed an elevated serum level of estradiol (669  pg/ml) associated with very low serum levels of follicular stimulating hormone and luteinizing hormone. Both pelvic ultrasound and magnetic resonance image showed a well-encapsulated mass lesion at right adnexa, measured 4.0 × 5.4 cm in size, containing mainly soft tissue with cystic component . (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Chia-Hao Liu, Huann-Cheng Horng, Wen-Hsun Chang, Peng-Hui Wang Tags: Correspondence Source Type: research

Poly(ADP-ribose) polymerase (PARP) inhibitors and ovarian cancer
There is still a big gap from the basic research (bench) to the clinical use (bed) in precise and personal therapy for patients with epithelial ovarian cancer (EOC) [1]. Because of slow progress in improving the outcome of EOC with chemotherapy over the past three decades, enthusiasm swelled for one of the targeted therapy, such as poly(ADP-ribose) polymerase (PARP) inhibitors which might be a part of the current treatment strategy when the positive results from the randomized, placebo-controlled, phase 3 trial (ENGOT-OV16/NOVA) conducted by the European Network for Gynecological Oncological Trial groups was obtained and p...
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Chia-Hao Liu, Yi Chang, Peng-Hui Wang Tags: Correspondence Source Type: research

Prenatal diagnosis of low-level mosaicism for trisomy 21 with rare karyotype detected by noninvasive prenatal testing
Trisomy 21 (Tri21), which causes the Down syndrome (DS), is the most common chromosome abnormality [1]. Patients with DS are always accompanied by intellectual disability, congenital heart disease and so on. Therefore, only 20% of Tri21 may progress to term delivery, but it is necessary to prevent the birth of neonatus with Tri21 [1,2]. Noninvasive prenatal testing (NIPT), which is the newest detection method, provides a more precise and fast screening method for the early detection of Tri21, and the detection rate is more than 99% [3]. (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - October 1, 2017 Category: OBGYN Authors: Hong Wu, Zong-Yu Miao, Xiao-Fei Hou, Xiao-Yan Liu, Hui-Yuan Shao Tags: Research Letter Source Type: research