Forthcoming Issues
Updates in the Management of Breast Cancer (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - November 4, 2022 Category: Surgery Source Type: research
Pathology of Breast Cancer
Although the normal anatomy of the breast is relatively simple, a myriad of hyperplastic, atypical, and frankly malignant processes exist. Though a histologic continuum exists, the natural progression of breast disease is not always on a continuum. Moreover, the distinction between hyperplastic, atypical, and frankly malignant processes rests on subtle qualitative and sometimes quantitative features. The treatment of breast-related lesions has always been, and continues to be, a multidisciplinary task. A general understanding of histopathologic features of breast disease will allow clinicians to identify scenarios that are...
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Omid Bakhtar Source Type: research
Clinical Trials in Breast Cancer
Randomized clinical trials have been essential in guiding the surgical and systemic treatment of breast cancer, with most focusing on de-escalation. Here, we discuss key clinical trials that have shaped the modern approach to the treatment of breast cancer, focusing on studies that are more recent. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Rick D. Vavolizza, Emily P. Rabinovich, Max O. Meneveau, Shayna L. Showalter Source Type: research
Genomic Profiling and Liquid Biopsies for Breast Cancer
The cancer genome plays an increasingly large role in the care of patients with breast cancer. Commercially available gene-expression profiling assays are now a part of staging and treatment guidelines, and their use continues to be examined in large-scale studies. With the advent of next-generation sequencing, the cancer genome can now be examined more quickly, less invasively, and in much greater detail. These technologies have led to a more nuanced understanding of molecular pathways, allowing providers to better match patients to clinical trials. Furthermore, a new era of diagnostics based on liquid biopsies is expecte...
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Clayton T. Marcinak, Muhammed Murtaza, Lee G. Wilke Source Type: research
Breast Cancer Screening Modalities, Recommendations, and Novel Imaging Techniques
This article reviews the fundamentals of mammography screening, current age-based mammography screening recommendations, supplemental breast cancer screening recommendations in high-risk women, and novel imaging technologies. This review summarizes recommendations from the American Society of Breast Surgeons and published guidelines from major societies to reflect a range of evidence-based perspectives regarding mammographic screening. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Sarah Nielsen, Anand K. Narayan Source Type: research
Operative Management in Stage IV Breast Cancer
Traditionally, surgical therapy for primary breast lesions in stage IV breast cancer has been reserved for palliation. Several retrospective studies have suggested a possible survival benefit with surgical resection of the primary tumor in patients with distant metastases. However, evidence from prospective, randomized controlled trials suggest that locoregional control provides no clear survival advantage for patients with stage IV breast cancer. Future areas of inquiry include identification of subsets of patients who may derive a survival benefit from locoregional control. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Sudheer R. Vemuru, Sarah E. Tevis Source Type: research
Postoperative Complications from Breast and Axillary Surgery
Although surgery of the breast and axilla is generally well-tolerated by patients, the breast surgeon recognizes that complications can occur even when operating with experience on the lowest risk patients. The operative repertoire ranges from breast conserving surgery, mastectomy (including skin-sparing and nipple-sparing types), to modified radical mastectomy, with each procedure carrying a different expected surgical morbidity. Patients and families who are fully informed of potential complications before their operation describe greater trust in their surgeon and are better able to co-manage complications with the surg...
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Sam Z. Thalji, Chandler S. Cortina, Meng S. Guo, Amanda L. Kong Source Type: research
Novel Approaches to Breast Reconstruction
As breast oncologic surgical procedures and approaches have evolved in recent years, so have breast reconstruction techniques. Newer advances focus on expanding the options of reconstructive approaches and patient selection, optimizing quality of life, and helping improve postsurgical survivorship. These advances span from techniques to expand criteria for nipple-sparing mastectomies, optimizing and enhancing oncoplastic surgery, evolving autologous reconstruction options, and preserving and restoring sensation after mastectomy. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Anne Warren Peled, Nicholas W. Clavin Source Type: research
Follow-up and Cancer Survivorship
This article reviews the recommendations for survivorship and the le vel of evidence supporting each aspect of high-quality survivorship care. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Heather B. Neuman, Jessica R. Schumacher Source Type: research
Changing Landscape of Breast Cancer Management
As surgeons who trained in general surgery before breast surgery became its own discipline, we as editors of this Surgical Clinics issue find the expanse of changes benefiting individuals with breast cancer to be remarkable. The surgical giants, Drs Seymour Schwartz, Folkert Belzer, and David Sabiston, could never have foreseen the advancements in specialty breast cancer care. It is hard to believe that we began our training before the routine use of core needle biopsy, sentinel lymph node biopsy, and full-panel genetic testing. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Anna Sanchez Seydel, Lee G. Wilke Tags: Preface Source Type: research
Radiation Treatment for Breast Cancer
Radiation treatment is a well-established component of breast cancer treatment, in both breast conservation and also for many patients who have had mastectomy as well as those with metastatic disease. The basis for this was established in multiple large meta-analyses, and multiple modern studies have further defined the role of radiation. The radiation must be delivered to the area at risk, which can include the partial breast, whole breast, chest wall, and/or regional lymph nodes. There are a number of acceptable radiation treatment techniques and dose-fractionation schedules that can be individualized to each patient. Ra...
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Anderson Bauer Source Type: research
Genetics of Breast Cancer
Genetic testing plays an important role in assessing breast cancer risk and often the risk of other types of cancers. Accurate risk assessment and stratification represents a critical element of identifying who is best served by increased surveillance and consideration of other prevention or treatment options while also limiting overtreatment and unnecessary testing. The indications for testing will likely continue to expand, and ideally, more women with a genetic predisposition to breast cancer will be identified before they are diagnosed with breast cancer and thus have the option to consider effective screening and prev...
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Marguerite M. Rooney, Krislyn N. Miller, Jennifer K. Plichta Source Type: research
Preoperative Systemic Therapy for Breast Cancer
The indications for preoperative/neoadjuvant systemic therapy in breast cancer have changed over the past few years. In this article, the authors review the current data for use of neoadjuvant therapy in inoperable and operable settings. The evolution of various neoadjuvant regimens used in triple-negative breast cancer, human epidermal growth factor receptor 2 (HER2) overexpressing/gene-amplified (HER2+) tumors, and hormone receptor positive breast cancer is discussed as well as the role of neoadjuvant chemotherapy in tailoring adjuvant treatment. (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 17, 2022 Category: Surgery Authors: Abhigna Kodali, Vijayakrishna K. Gadi Source Type: research
Pediatric Surgery
SURGICAL CLINICS OF NORTH AMERICA (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 1, 2022 Category: Surgery Authors: JOHN D. HORTON Source Type: research
Copyright
ELSEVIER (Source: Surgical Clinics of North America)
Source: Surgical Clinics of North America - October 1, 2022 Category: Surgery Source Type: research
