The microbiome of the appendix differs in patients with and without appendicitis: A prospective cohort study
Appendicitis seems to be a disease of infectious origin, but the detailed pathogenesis is unknown. We aimed to investigate the microbiome of the appendix lumen in patients with and without appendicitis, including a comparison of the subgroups of complicated versus uncomplicated appendicitis. (Source: Surgery)
Source: Surgery - April 1, 2024 Category: Surgery Authors: Siv Fonnes, Sarah Mollerup, Sarah Juel Paulsen, Barbara Juliane Holzknecht, Henrik Westh, Jacob Rosenberg Source Type: research
Care fragmentation in hepatopancreatic surgery and postoperative outcomes
Practice fragmentation in surgery may be associated with poor quality of care. We sought to define the association between fragmented practice and outcomes in hepatopancreatic surgery relative to surgeon volume and sex. (Source: Surgery)
Source: Surgery - April 1, 2024 Category: Surgery Authors: Zayed Rashid, Muhammad Musaab Munir, Selamawit Woldesenbet, Diamantis I. Tsilimigras, Mujtaba Khalil, Muhammad Muntazir Mehdi Khan, Vivian Resende, Mary Dillhoff, Aslam Ejaz, Timothy M. Pawlik Source Type: research
The conundrum of ostomy formation
We would like to express our gratitude for the attention and comments from our colleagues from the United Kingdom. Their contribution has raised a “hot topic” beyond the recently published long-term results of prophylactic mesh in end colostomy formation.1,2 It explores a supplementary unanswered question: Which is the best way to create a stoma? (Source: Surgery)
Source: Surgery - April 1, 2024 Category: Surgery Authors: Mireia Verdaguer-Tremolosa, Josep Maria Garcia-Alamino, Victor Rodrigues-Gon çalves, Maria Pilar Martínez-López, Manuel López-Cano Source Type: research
Billroth-II modified with hinged anti-peristaltic afferent loop versus Roux-en-Y reconstruction after distal gastrectomy for gastric cancer: A propensity-score match analysis
This study aimed to evaluate the effectiveness of modified Billroth-II with a hinged anti-peristaltic afferent loop by comparing it with the Roux-en-Y method. (Source: Surgery)
Source: Surgery - March 26, 2024 Category: Surgery Authors: Dang Quang Thong, Ho Le Minh Quoc, Tran Quang Dat, Nguyen Viet Hai, Doan Thuy Nguyen, Nguyen Vu Tuan Anh, Nguyen Lam Vuong, Nguyen Hoang Bac, Vo Duy Long Source Type: research
Carnitine palmitoyltransferase 1B mediates gemcitabine resistance in pancreatic cancer
The incidence of pancreatic cancer is rising, with pancreatic ductal adenocarcinoma (PDAC) accounting for approximately 90% of all pancreatic cancers.1 A diagnosis of PDAC is especially grim, with 5-year survival rates currently at 13% just this year. The commonality among National Comprehensive Cancer Network clinical practice guidelines is the recommendation to undergo chemotherapy, although timing depends on alternative treatment modalities, such as surgery and radiation, which is dependent on staging, resectability, and surgical candidacy. (Source: Surgery)
Source: Surgery - March 25, 2024 Category: Surgery Authors: Michael K. Srienc, Timothy R. Donahue Source Type: research
Long-term outcomes after spleen-preserving distal pancreatectomy with splenic vessels preservation or resection: A nationwide survey of the Japanese Society of Pancreatic Surgery
This study aimed to evaluate the long-term outcomes of spleen-preserving distal pancreatectomy with splenic vessel resection and spleen-preserving distal pancreatectomy with splenic vessel preservation. (Source: Surgery)
Source: Surgery - March 24, 2024 Category: Surgery Authors: Hiromitsu Maehira, Masaji Tani, Haruki Mori, Daisuke Ichikawa, Mampei Kawashima, Hiroshi Tajima, Yuichi Nagakawa, Isamu Makino, Shintaro Yagi Source Type: research
Risk factors, patterns, and outcome predictors of late recurrence in patients with hepatocellular carcinoma after curative resection: A large cohort study with long-term follow-up results
This study aims to explore the risk factors and patterns of late recurrence and predictors of subsequent outcome. (Source: Surgery)
Source: Surgery - March 24, 2024 Category: Surgery Authors: Chih-Yang Hsiao, Cheng-Maw Ho, Ming-Chih Ho, Hou-Ying Cheng, Yao-Ming Wu, Po-Huang Lee, Rey-Heng Hu Source Type: research
Preoperative difficulty assessment of interval laparoscopic cholecystectomy for gallstones
In this study, we evaluated the difficulties associated with interval cholecystectomy for cholecystitis with gallstones. (Source: Surgery)
Source: Surgery - March 24, 2024 Category: Surgery Authors: Masahiro Shiihara, Yasuhiro Sudo, Norimasa Matsushita, Takeshi Kubota, Yasuhiro Hibi, Harushi Osugi, Tatsuo Inoue Source Type: research
Using risk-adjusted cumulative sum to evaluate surgeon, divisional, and institutional outcomes —a feasibility study
The objective of this study was to demonstrate the feasibility of using risk-adjusted cumulative sum to monitor outcomes after colorectal operations and identify clinically relevant performance variations. (Source: Surgery)
Source: Surgery - March 23, 2024 Category: Surgery Authors: Kyle W. Blackburn, Laura E. Cooper, Andrea C. Bafford, Yinin Hu, Rebecca F. Brown Source Type: research
Integration of smartphone-based mobile health technology into perioperative care —the patient’s perspective
Although numerous use cases demonstrate the value of mobile health technology, there is limited knowledge regarding patient perceptions of such technology, which may explain the lack of broader implementation of mobile health technology. Achieving meaningful, sustained, and equitable use of mobile health technology in surgery necessitates a human-centered design approach with consideration given to end users. This review article draws on evidence from prior qualitative studies of both surgeons and patients to make recommendations that may assist health care systems in realizing the full potential of mobile health technolog...
Source: Surgery - March 21, 2024 Category: Surgery Authors: Robert D. Sinyard, Nikhil Panda Source Type: research
Understanding the length of hospital stay after general surgery using a prospectively maintained local database
We read with interest the study by Jensen et al that demonstrated the feasibility of remote surgical triage at freestanding emergency departments (EDs).1 To complement this, we analyzed a prospectively maintained local database to understand the length of hospital stay (LOS) in general surgery patients who require inpatient admissions. (Source: Surgery)
Source: Surgery - March 21, 2024 Category: Surgery Authors: Joshua G. Kovoor, Nasim Nematzadeh, Sara Ataie, Bev Thomas, Rachel Short, Amy Davey, Angie Goodrich, Tapaswi Shrestha, Aashray K. Gupta, Brandon Stretton, Stephen Bacchi, Matthew Marshall-Webb, Reto Kaeppeli, Maziar Navidi, Chrisanthi Liyanage, Guy J. Mad Source Type: research
Critical appraisal of surgical margins according to KRAS status in liver resection for colorectal liver metastases: Should surgical strategy be influenced by tumor biology?
KRAS mutation is a negative prognostic factor for colorectal liver metastases. Several studies have investigated the resection margins according to KRAS status, with conflicting results. The aim of the study was to assess the oncologic outcomes of R0 and R1 resections for colorectal liver metastases according to KRAS status. (Source: Surgery)
Source: Surgery - March 21, 2024 Category: Surgery Authors: Rami Rhaiem, Adrien Duram é, Florian Primavesi, Dimitri Dorcaratto, Nicholas Syn, Ángela de la Hoz Rodríguez, Aurélien Dupré, Tullio Piardi, Gerardo Blanco Fernández, Arancha Prada Villaverde, Juan C. Rodríguez Sanjuán, Roberto Fernández Santiago Source Type: research
Clinician overconfidence in visual estimation of the posthepatectomy liver remnant volume: A proximal source of liver failure after major hepatic resection?
Post-hepatectomy liver failure is a source of morbidity and mortality after major hepatectomy and is related to the volume of the future liver remnant. The accuracy of a clinician ’s ability to visually estimate the future liver remnant without formal computed tomography liver volumetry is unknown. (Source: Surgery)
Source: Surgery - March 21, 2024 Category: Surgery Authors: Camelia Forton, Victor Sandoval, Issac R. Schwantes, Ranish K. Patel, Kenneth J. Kolbeck, Elizabeth N. Dewey, Elena K. Korngold, Skye C. Mayo Source Type: research
Exacerbated ischemia-reperfusion injury in fatty livers is mediated by lipid peroxidation stress and ferroptosis
Ischemia-reperfusion injury is a common problem in liver surgery and transplantation. Although ischemia-reperfusion injury is known to be more pronounced in fatty livers, the underlying mechanisms for this difference remain poorly understood. We hypothesized that ferroptosis plays a significant role in fatty liver ischemia-reperfusion injury due to increased lipid peroxidation in the presence of stored iron in the fatty liver. To test this hypothesis, the ferroptosis pathway was evaluated in a murine fatty liver ischemia-reperfusion injury model. (Source: Surgery)
Source: Surgery - March 20, 2024 Category: Surgery Authors: Zachary P. Rokop, Wenjun Zhang, Nandini Ghosh, Nirupam Biswas, Amitava Das, Jingmei Lin, Chandan K. Sen, Chandrashekhar Kubal Source Type: research
Feasibility of tele-visits after elective ventral hernia surgery: Experience from an Indian tertiary care center
The COVID-19 pandemic has disrupted traditional postoperative follow-up for elective surgeries, prompting a rapid shift to telehealthcare, as evidenced in high-income countries with robust electronic medical record linkage and ancillary support teams.1,2 However, adoption in low- and middle-income countries (LMICs) is scarce, particularly with challenges faced by a considerable rural patient population. In our early experience at an Indian tertiary care center, we closely followed up with patients who underwent elective ventral hernia repair (VHR), employing both in-person and telephonic approaches. (Source: Surgery)
Source: Surgery - March 18, 2024 Category: Surgery Authors: Varun V. Bansal, Yash Kamath, Sahil Waghmare, Monty U. Khajanchi, Nobhojit Roy Source Type: research
