Stereotactic ablative radiotherapy for unresectable inferior vena cava tumor thrombus in a patient with renal cell carcinoma: a case report
ConclusionSBRT appears to be a feasible and safe treatment for IVC-TT secondary to RCC in patients who are not candidates for surgery. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 2, 2023 Category: Cancer & Oncology Source Type: research
Impact of dose escalation on colostomy-free survival and treatment outcome in squamous cell anal carcinoma
ConclusionDose escalation> 63 Gy (maximum 66.6 Gy) may improve CFS and PFS for certain subgroups, with a concomitant increase in chronic skin toxicities. Modern IMRT seems to be associated with an improvement in OS. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 2, 2023 Category: Cancer & Oncology Source Type: research
Second course of re-irradiation in pediatric diffuse intrinsic pontine glioma
ConclusionA second course of re-irradiation can be an additional tool in patients with progressive disease after first- and second-line irradiation. It is unclear whether and to what extent it contributes to progression-free survival prolongation and if—since our patient was asymptomatic—progression-assoc iated neurological deficits can be alleviated. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 2, 2023 Category: Cancer & Oncology Source Type: research
Low doses to the heart in daily practice for treating left-sided breast cancer using accelerated partial-breast irradiation by multicatheter brachytherapy and deep-inspiration breath-hold using a SIB
ConclusionIn daily practice, both DIBH radiation therapy as well as MCBT show a very low heart exposure and may thus reduce long term cardiac morbidity as compared to currently available long-term clinical data of patients treated with conventional tangential field plans in free breathing. Our analysis confirms particularly good cardiac sparing with MCBT-APBI, so that this te chnique should be offered to patients with left-sided breast cancer if the tumor-associated eligibility criteria are fulfilled. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 24, 2023 Category: Cancer & Oncology Source Type: research
Organerhaltende Therapie des muskelinvasiven Blasenkarzinoms: 10-Jahres-Daten der britischen BC2001-Studie
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 23, 2023 Category: Cancer & Oncology Source Type: research
Mobile applications in radiation oncology —current choices and future potentials
ConclusionApps used in (and for) scientific research in radiation oncology are rarely available for patients and HCP in common marketplaces. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 21, 2023 Category: Cancer & Oncology Source Type: research
Robotic stereotactic body radiotherapy for localized prostate cancer: final analysis of the German HYPOSTAT trial
ConclusionRobotic SBRT with 35 Gy in 5 fractions was associated with a favorable short-term toxicity profile. Recruitment for the HYPOSTAT‑2 trial (ARO-2018‑4; NCT03795337), which further analyses the late toxicity of this regimen with a planned sample size of 500 patients, is ongoing. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 9, 2023 Category: Cancer & Oncology Source Type: research
Kardiovaskul äre Risikoevaluation in der Behandlung des Hodgkin-Lymphoms – auf dem Weg zur individualisierten Planung?
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 7, 2023 Category: Cancer & Oncology Source Type: research
SBRT von prim ären Nierenzellkarzinomen – Langzeitergebnisse der IROCK-Datenbank
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 6, 2023 Category: Cancer & Oncology Source Type: research
Cardiac radioablation of incessant ventricular tachycardia in patients with terminal heart failure under permanent left ventricular assist device therapy —description of two cases
ConclusioncRA might serve as a last resort strategy for patients with terminal heart failure undergoing LVAD therapy and displaying incessant VT. Intermediate- and long-term outcomes of these seriously ill patients often remain poor; therefore, best supportive care strategies should also be evaluated as long as no clear benefic ial effects of cRA procedures can be shown. For patients treated with cRA under running ventricular rhythm abnormality, strategies for post-procedural generation of stabilized rhythm have to be established. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 3, 2023 Category: Cancer & Oncology Source Type: research
Linac-based stereotactic salvage reirradiation for intraprostatic prostate cancer recurrence: toxicity and outcomes
ConclusionLinac-based SBRT is a safe technique for performing Re‑I for intraprostatic recurrence after primary curative radiotherapy for PC. Future prospective, randomized studies are desirable to better understand the effectiveness of reirradiation and the still open questions in this field. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 2, 2023 Category: Cancer & Oncology Source Type: research
Chemoradiotherapy for untreated Masaoka –Koga stage IVB thymic carcinoma: a single-center retrospective study
ConclusionsChemoradiotherapy used as the first-line treatment improved ORR and PFS in Masaoka –Koga stage IVB TC patients. Patients receiving more cycles of chemotherapy may have a better chance to benefit from chemoradiotherapy. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 2, 2023 Category: Cancer & Oncology Source Type: research
Preoperative radiotherapy with concomitant chemotherapy in extremity soft tissue sarcomas: long-term results of a single center
ConclusionAn increased risk for local failure seems to exist for patients with relapsed tumor on admission and having positive surgical margins after neoadjuvant RCT. Intensity of chemotherapy influenced DSS but not OS, which could be due to younger patients receiving MAP. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - February 1, 2023 Category: Cancer & Oncology Source Type: research
Improving CBCT image quality to the CT level using RegGAN in esophageal cancer adaptive radiotherapy
ConclusionThe proposed deep-learning RegGAN model seems promising for generation of high-quality sCT images from stand-alone thoracic CBCT images in an efficient way and thus has the potential to support CBCT-based esophageal cancer adaptive radiotherapy. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - January 23, 2023 Category: Cancer & Oncology Source Type: research
Verl ängerung des Gesamtüberlebens durch die Impfung von autologen tumorlysatbeladenen dendritischen Zellen (DCVax-L) bei Patienten mit neu diagnostiziertem und rezidivierendem Glioblastom
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - January 20, 2023 Category: Cancer & Oncology Source Type: research