Co-encapsulation of HNF4 α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure
Acute liver failure (ALF) is a complicated condition that is characterized by global hepatocyte death and often requires immediate liver transplantation. However, this therapy is limited by shortage of donor o... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 23, 2020 Category: Stem Cells Authors: Defu Kong, Huiming Xu, Mo Chen, Yeping Yu, Yongbing Qian, Tian Qin, Ying Tong, Qiang Xia and Hualian Hang Tags: Research Source Type: research
HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway
Heat shock protein B7 (HSPB7), which belongs to small heat shock protein family, has been reported to be involved in diverse biological processes and diseases. However, whether HSPB7 regulates osteogenic differen... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 23, 2020 Category: Stem Cells Authors: Chanyuan Jin, Ting Shuai and Zhihui Tang Tags: Research Source Type: research
Regenerative medicine approaches for the management of respiratory tract fistulas
Respiratory tract fistulas (or fistulae) are abnormal communications between the respiratory system and the digestive tract or the adjacent organs. The origin can be congenital or, more frequently, iatrogenic ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 23, 2020 Category: Stem Cells Authors: Angelo Trivisonno, Dania Nachira, Ivo Bo škoski, Venanzio Porziella, Giuliana Di Rocco, Silvia Baldari and Gabriele Toietta Tags: Review Source Type: research
Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor- β1 in wound healing
Scar formation, which may be caused by myofibroblast aggregations, is the greatest challenge during skin wound healing in the clinical setting. Studies have indicated that epidermal stem cells (EPSC) improve w... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 23, 2020 Category: Stem Cells Authors: Mengna Duan, Yan Zhang, Haiyang Zhang, Yupeng Meng, Ming Qian and Guokun Zhang Tags: Research Source Type: research
Correction to: Epidermal stem cells in wound healing and their clinical applications
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 22, 2020 Category: Stem Cells Authors: Ronghua Yang, Fengxia Liu, Jingru Wang, Xiaodong Chen, Julin Xie and Kun Xiong Tags: Correction Source Type: research
DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages
Dysfunction of the DNA methylation was associated with stem cell reprogramming. Moreover, DNA methyltransferase 1 (DNMT1) deficiency was involved in the differentiation of hair follicle stem cell (HFSc), but t... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 19, 2020 Category: Stem Cells Authors: Fangcao Jin, Min Li, Xuyang Li, Yunpeng Zheng, Kun Zhang, Xiaojun Liu, Bingjie Cai and Guangwen Yin Tags: Research Source Type: research
Efficacy and safety of stem cell therapy for the early-stage osteonecrosis of femoral head: a systematic review and meta-analysis of randomized controlled trials
Osteonecrosis of femoral head (ONFH) is a seriously degenerative disease with no effective therapies to slow its progression. Several studies have reported short-term efficacy of stem cells on early-stage ONFH... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 19, 2020 Category: Stem Cells Authors: Lianghao Mao, Pan Jiang, Xuan Lei, Chenlie Ni, Yiming Zhang, Bing Zhang, Qiping Zheng and Dapeng Li Tags: Review Source Type: research
Correction to: MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 19, 2020 Category: Stem Cells Authors: Mengge Wang, Hongtao Wang, Yuqi Wen, Xiaoyuan Chen, Xin Liu, Jie Gao, Pei Su, Yuanfu Xu, Wen Zhou, Lihong Shi and Jiaxi Zhou Tags: Correction Source Type: research
Correction to: Extracellular vesicles from human mesenchymal stem cells expedite chondrogenesis in 3D human degenerative disc cell cultures
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 16, 2020 Category: Stem Cells Authors: Daphne Hingert, Karin Ekstr öm, Jonathan Aldridge, Rossella Crescitelli and Helena Brisby Tags: Correction Source Type: research
Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system
Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 15, 2020 Category: Stem Cells Authors: Yue Zhang, Fanhong Zeng, Xu Han, Jun Weng and Yi Gao Tags: Review Source Type: research
Application of human amniotic epithelial cells in regenerative medicine: a systematic review
Human amniotic epithelial cells (hAECs) derived from placental tissues have gained considerable attention in the field of regenerative medicine. hAECs possess embryonic stem cell-like proliferation and differe... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 15, 2020 Category: Stem Cells Authors: Qiuwan Zhang and Dongmei Lai Tags: Review Source Type: research
BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response
Wharton ’s jelly-derived mesenchymal stem cells (WJ-MSCs) from the human umbilical cord have been studied extensively due to their immunomodulatory functions. Large-conductance Ca2+-activated K+ (BKCa channels) ch... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 15, 2020 Category: Stem Cells Authors: Ahui Song, Jingjing Wang, Yan Tong, Junyan Fang, Yi Zhang, Huiping Zhang, Hongqiang Ruan, Kai Wang and Yingli Liu Tags: Research Source Type: research
TUG1 enhances high glucose-impaired endothelial progenitor cell function via miR-29c-3p/PDGF-BB/Wnt signaling
Diabetes is associated with the dysfunction of endothelial progenitor cells (EPCs), characterized as impaired angiogenesis, a phenomenon thought to be involved in the development of diabetic foot. lncRNA plays... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 15, 2020 Category: Stem Cells Authors: Yang Li, Kangkang Zhi, Shilong Han, Xue Li, Maoquan Li, Weishuai Lian, Haijun Zhang and Xiaoping Zhang Tags: Research Source Type: research
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage
Bone marrow mesenchymal stem cells (BMSCs) have been used as important cell-based tools for clinical applications. Oxidative stress-induced apoptosis causes a low survival rate after transplantation, and the u... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 15, 2020 Category: Stem Cells Authors: Chongxi Fan, Jianyu Feng, Chi Tang, Zhengbin Zhang, Yingtong Feng, Weixun Duan, Mingming Zhai, Zedong Yan, Liwen Zhu, Lele Feng, Hanzhao Zhu and Erping Luo Tags: Research Source Type: research
Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel
Mesenchymal stem cells are a promising cell source for chondrogenic differentiation and have been widely used in several preclinical and clinical studies. However, they are prone to an unwanted differentiation... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 9, 2020 Category: Stem Cells Authors: Shahrbanoo Jahangir, David Eglin, Naomi P ötter, Mojtaba Khozaei Ravari, Martin J. Stoddart, Ali Samadikuchaksaraei, Mauro Alini, Mohammadreza Baghaban Eslaminejad and Majid Safa Tags: Research Source Type: research
