Pancreatic cancer mortality in South Africa: A case-control study
CONCLUSION: Smoking and certain occupations increased the risk of pancreatic cancer mortality. Further research is needed to evaluate the associations between other extrinsic and intrinsic factors and pancreatic cancer mortality.PMID:38525629 | DOI:10.7196/SAMJ.2024.v114i1.1132 (Source: South African Medical Journal)
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: M L Nhleko I Edoka E Musenge Source Type: research

Informal gold miners with mercury toxicity: Novel asymmetrical neurological presentations
S Afr Med J. 2023 Dec 4;113(12):20. doi: 10.7196/SAMJ.2023.v113i12.1127.ABSTRACTMercury is a highly toxic heavy metal that may cause neurological, respiratory, gastrointestinal and dermatological illnesses. Previously described neurological manifestations of mercury toxicity are symmetrical, and include a pancerebellar syndrome, generalised seizures and encephalopathy. Mercury is used in the gold mining process, and in artisanal or illicit gold mining, often without necessary protection. Here we describe the cases of two artisanal gold miners from western Johannesburg, South Africa, who presented with atypical neurological...
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: J George E Sadiq I Moola S Maharaj A Mochan Source Type: research

The characteristics of dermatology inpatients seen at the quaternary Inkosi Albert Luthuli Central Hospital in Durban, South Africa, over a 5-year period - 2015 - 2020
CONCLUSION: A broad range of diagnoses is managed through the dermatology inpatient service, particularly as consultations. These services remain essential in the holistic management of patients.PMID:38525631 | DOI:10.7196/SAMJ.2024.v114i1.1098 (Source: South African Medical Journal)
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: L Mthembu J T Masuka K Duze A Mosam Source Type: research

Dyslipidaemia in patients with chronic kidney disease - a neglected cardiovascular risk factor
CONCLUSION: This cohort comprised a large proportion of patients classified as high or very high risk for ASCVD. Despite this, the use of LLT was inadequate, and <20% of patients were at target LDL-C levels. These data suggest a greater need for awareness of initiating LLT to achieve recommended target LDL-C levels in patients with CKD.PMID:38525632 | DOI:10.7196/SAMJ.2023.v113i11.1089 (Source: South African Medical Journal)
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: M R Essop F Seedat F J Raal Source Type: research

Antivirals for the treatment of mild and moderate COVID-19 in South Africa
S Afr Med J. 2023 Dec 4;113(12):33. doi: 10.7196/SAMJ.2023.v113i12.1066.ABSTRACTWhile the majority of COVID-19 cases in South Africa (SA) are mild, patients with severe COVID-19 requiring hospitalisation present with significant morbidity and mortality and place a substantial burden on healthcare services. Given the low vaccine uptake in SA and other low- and middle-income countries in sub-Saharan Africa, the high prevalence of comorbidities and limited healthcare system capacity, evidence-based interventions that reduce the risk of severe disease and death should be considered for implementation. Several antiviral classes...
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: R Perumal V Naidoo S Govender T N Gengiah Source Type: research