Systematic review and meta-analysis of observational studies to understand the prevalence of restless legs syndrome in multiple sclerosis: An update
Multiple sclerosis (MS) is related to the demyelination of intracranial nerves at multiple sites, while restless legs syndrome (RLS) appears to be caused by dysfunction of the dopaminergic system. Since RLS prevalence is higher among MS patients than in the general population, we carried out an updated meta-analysis to understand whether the two diseases might be associated. (Source: Sleep Medicine)
Source: Sleep Medicine - June 20, 2018 Category: Sleep Medicine Authors: Pingping Ning, Fayun Hu, Baiyuan Yang, Qiuyan Shen, Quanzhen Zhao, Hongyan Huang, Ran An, Yalan Chen, Hui Wang, Xinglong Yang, Yanming Xu Tags: Original Article Source Type: research
Trends of cost-effectiveness studies in sleep medicine
This study provides an overview of the growth of the use of cost-effectiveness analyses to quantify the outcomes of sleep related interventions. It also identifies highly prevalent sleep disorders, which despite having a high burden of disease, lack basic utility studies. (Source: Sleep Medicine)
Source: Sleep Medicine - June 15, 2018 Category: Sleep Medicine Authors: Babak Mohit, Joshua T. Cohen Tags: Review Article Source Type: research
Effectiveness of cognitive behavioral therapy for pharmacotherapy-resistant chronic insomnia: a multi-center randomized controlled trial in Japan
This study evaluated the effectiveness of add-on cognitive behavioral therapy for insomnia (CBT-I) and GABAA-RA dose-tapering in patients with primary insomnia resistant to pharmacotherapy. (Source: Sleep Medicine)
Source: Sleep Medicine - June 15, 2018 Category: Sleep Medicine Authors: Naoko Ayabe, Isa Okajima, Shun Nakajima, Yuichi Inoue, Norio Watanabe, Wataru Yamadera, Naohisa Uchimura, Hisateru Tachimori, Yuichi Kamei, Kazuo Mishima Source Type: research
Sleep-Related Erection Neurophysiology: A Journey of Discovery
Michel Jouvet established a tradition of sleep neurophysiology that inspired several generations of sleep researchers. When I arrived in his laboratory in 1991, it was known that erection cycles occur during rapid eye movement (REM) sleep in humans. However, it was not known if such erections in sleep occurred in other species, or how REM-related erections were controlled. Employing the classical techniques and systematic approach of Jouvet and his team, I embarked on a journey of discovery. Not only were fundamental principles of REM-related erectile control identified, such as the critical role of the lateral preoptic ar...
Source: Sleep Medicine - June 14, 2018 Category: Sleep Medicine Authors: Markus H. Schmidt Source Type: research
Validating the Persian Adolescent Sleep Hygiene Scale-Revised (ASHSr) using comprehensive psychometric testing methods
This study translated the Adolescent Sleep Hygiene Scale-revised (ASHSr) into Persian and aimed to validate its psychometric properties using classical test theory and Rasch analyses. (Source: Sleep Medicine)
Source: Sleep Medicine - June 12, 2018 Category: Sleep Medicine Authors: Chung-Ying Lin, Carol Strong, Andrew M.H. Siu, Shabnam Jalilolghadr, Per Nilsen, Anders Brostr öm, Amir H. Pakpour Tags: Original Article Source Type: research
Sleep disturbances and sleep disorders in adults living with chronic pain: A meta-analysis
This study meta-analysed the findings from studies that used objective polysomnographic measures of sleep or examined diagnosed sleep disorders in people with CP. (Source: Sleep Medicine)
Source: Sleep Medicine - June 11, 2018 Category: Sleep Medicine Authors: J.L. Mathias, M.L. Cant, A.L.J. Burke Tags: Original Article Source Type: research
Association between mild or moderate obstructive sleep apnea-hypopnea syndrome and cognitive dysfunction in children
This study aims to investigate the association between mild or moderate childhood OSAHS and cognitive dysfunction. (Source: Sleep Medicine)
Source: Sleep Medicine - June 9, 2018 Category: Sleep Medicine Authors: Jing Zhao, Shujing Han, Jishui Zhang, Guixiang Wang, Hua Wang, Zhifei Xu, Jun Tai, Xiaoxia Peng, Yongli Guo, Haihong Liu, Jinghong Tian, Xin Jin, Li Zheng, Jie Zhang, Xin Ni Tags: Original Article Source Type: research
Association between mild or moderate obstructive sleep apnea hypopnea syndrome and cognitive dysfunction in children
This study aims to investigate the association between mild or moderate childhood OSAHS and cognitive dysfunction. (Source: Sleep Medicine)
Source: Sleep Medicine - June 9, 2018 Category: Sleep Medicine Authors: Jing Zhao, Shujing Han, Jishui Zhang, Guixiang Wang, Hua Wang, Zhifei Xu, Jun Tai, Xiaoxia Peng, Yongli Guo, Haihong Liu, Jinghong Tian, Xin Jin, Li Zheng, Jie Zhang, Xin Ni Tags: Original Article Source Type: research
Jouvet's animal model of RBD, clinical RBD, and their relationships to REM sleep mechanisms
This article focuses on the contributions made by Michel Jouvet concerning the systems responsible for the muscle atonia of paradoxical sleep (REM sleep). He was the first to describe the brainstem system mechanisms responsible for muscle atonia during paradoxical sleep using pontine cats and localized pontine lesions. Also discussed is the research going on in the eighties, when Michel Jouvet was hunting for the hypnogenetic factor. At that time, he thought that it was secreted by the hypophysis; but it finally turned out to be controlled by the hypocretin/orexin and melanin concentrating hormone neurones located in the l...
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Pierre-Herv é Luppi Tags: Original Article Source Type: research
Neonatal sleep, a genetically-driven rehearsal before the show: an endless encounter with Michel Jouvet
In this short review, I would like to share some personal memories about the insights and achievements of Michel Jouvet in the field of sleep ontogeny. The first time I met Michel Jouvet was in 1972 when he accepted to chair my thesis on sleep, the research work being preformed in Howard Roffwarg's lab in New York. From then on we had many discussions together about the mechanisms and nature of neonatal Paradoxical Sleep, notably its characteristic muscular “twitches”. The idea emerged of a genetically programmed pattern of motor activation responsible for this state of “seismic” sleep. (Source: Sleep Medicine)
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Joelle Adrien Tags: Original Article Source Type: research
The Insomnia Of Franz Kafka
To characterize the insomnia suffered by Franz Kafka (1883-1924), one of the most important literary figures of the 20th century. (Source: Sleep Medicine)
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: A. Iranzo, A. Stefani, B. H ögl, J. Santamaria, SINBAR Tags: Historical Issues in Sleep Medicine Source Type: research
Will daytime occupational noise exposures induce nighttime sleep disturbance?
Nighttime environmental noise affects sleep quality. However, the effects of daytime occupational noise remain unclear. (Source: Sleep Medicine)
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Cheng-Yu Lin, Perng-Jy Tsai, Kuei-Yi Lin, Chih-Yong Chen, Lin-Hui Chung, Jiunn-Liang Wu, Yueliang Leon Guo Tags: Original Article Source Type: research
Jouvet ’s animal model of RBD, clinical RBD, and their relationships to REM sleep mechanisms
This article focuses on the contributions made by Michel Jouvet concerning the systems responsible for the muscle atonia of paradoxical sleep (REM sleep). He was the first to describe the brainstem system mechanisms responsible for muscle atonia during paradoxical sleep using pontine cats and localized pontine lesions. Also discussed is the research going on in the eighties, when Michel Jouvet was hunting for the hypnogenetic factor. At that time, he thought that it was secreted by the hypophysis; but it finally turned out to be controlled by the hypocretin/orexin and melanin concentrating hormone neurones located in the l...
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Pierre-Herv é Luppi Tags: Original Article Source Type: research
Modafinil: its discovery, the early European and North American experience in the treatment of narcolepsy and idiopathic hypersomnia, and its subsequent use in other medical conditions
Adrafinil, a new molecule identified by a French drug company, L. Lafon Ltd, in 1974, turned out to cause a significant dose-dependent increase in motor activity in mice, without exerting peripheral sympathomimetic effects. As early as 1977-78, Michel Jouvet prescribed adrafinil to narcoleptic patients, but without consistent results. Meanwhile the kinetics of adrafinil led to the identification of an active metabolite, modafinil. In 1983, Jouvet and Bastugi prescribed modafinil to narcoleptic and idiopathic hypersomnia patients and obtained a significant decrease of excessive daytime sleepiness and sleep attacks in a majo...
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Michel Billiard, Roger Broughton Tags: Original Article Source Type: research
Neonatal sleep, a genetically-driven rehearsal before the show: An infinite encounter with Michel Jouvet
n this short review, I would like to share some personal memories about the insights and achievements of Michel Jouvet in the field of sleep ontogeny. The first time I met Michel Jouvet was in 1972 on the subject of the ontogeny of Paradoxical Sleep. Michel Jouvet had accepted to chair my thesis on sleep in the kitten, a work performed at Howard Roffwarg ’s lab in New York. From then on we had many discussions together about the mechanisms and nature of neonatal Paradoxical Sleep, notably its characteristic muscular “twitches”. (Source: Sleep Medicine)
Source: Sleep Medicine - June 6, 2018 Category: Sleep Medicine Authors: Joelle Adrien Tags: Original Article Source Type: research
