Xdemvy < sup > TM < /sup > (Lotilaner Ophthalmic Solution) 0.25% Topical Solution for the Treatment of < em > Demodex < /em > Blepharitis
Skinmed. 2024 Mar 18;22(1):61-66. eCollection 2024.ABSTRACTXdemvyTM (lotilaner ophthalmic solution) 0.25% topical solution was recently approved for the treatment of Demodex blepharitis in adults aged ≥18 years. As an antiparasitic agent, lotilaner selectively inhibits gamma-aminobutyric acid chloride channels specific to the parasite and induces spastic paralysis, leading to death of Demodex blepharitis mites. In two randomized, double-masked, vehicle-controlled, multi-center, phase-3 clinical trials (Saturn-1 and Satuirn-2), lotilaner 0.25% topical solution was investigated for the treatment of Demodex blepharitis. Pat...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Aditya K Gupta Avantika Mann Kimberly Vincent William Abramovits Source Type: research
Zoonotic Majocchi's Granuloma of the Vulva
Skinmed. 2024 Mar 18;22(1):67-68. eCollection 2024.ABSTRACTA healthy 32-year-old woman presented to clinic with tender pruritic lesions of 2-month duration at the vulva and lesions for weeks on the shins. She was treated with topical corticosteroids and intravenous vancomycin without significant improvement. On examination, dozens of follicular hemorrhagic papulopustules were detected at the suprapubic area and vulva (Figure 1). Similar but less prominent lesions were observed on the shins as well. Biopsies of the vulva and shin revealed a follicular inflammatory infiltrate of neutrophils, histiocytes, and lymphocytes as w...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Larissa M Pastore Camille E Introcaso Source Type: research
Diagnostic Dilemma of an Adult-Onset Vascular Tumor
Skinmed. 2024 Mar 18;22(1):69-70. eCollection 2024.NO ABSTRACTPMID:38494620 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Sanjiv Choudhary Ankita Srivastava Rasika Gadkari Source Type: research
Preoperative Labile Hypertension with a Perioperative Resolution during Hair Transplant Surgery
Skinmed. 2024 Mar 18;22(1):72-78. eCollection 2024.NO ABSTRACTPMID:38494621 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Smriti Shrestha Dhiraj Kc Barun Bahadur Pradhan Kamal Subedi Aseem Sharma Source Type: research
Clinical and Temporal Characteristics of Malignancy-Associated Prurigo Nodularis: A Systematic Review
Skinmed. 2024 Mar 18;22(1):74-78. eCollection 2024.NO ABSTRACTPMID:38494622 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Maxwell Green Laura Williams Drew Kuraitis Source Type: research
Tranexamic Acid (TXA) Infiltration: An Effective Option for Reducing Bleeding during Mohs Micrographic Surgery (MMS) in Patients on Anticoagulant Therapy
Skinmed. 2024 Mar 18;22(1):76-78. eCollection 2024.NO ABSTRACTPMID:38494623 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Sujitha Yadlapati Subuhi Kaul Faraz Yousefian Valeria Gonzalez-Molina Leah Shama-Brown Source Type: research
Earlobe Cross-Over Reconstruction: A Novel Approach to Prevent Rim Notching of the Helical Rim
Skinmed. 2024 Mar 18;22(1):77-78. eCollection 2024.NO ABSTRACTPMID:38494624 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Deirdre Connolly Heather Hamilton Nazanin Saedi Michael Kaminer Source Type: research
Atlas of Genital Dermoscopy
Skinmed. 2024 Mar 18;22(1):80. eCollection 2024.NO ABSTRACTPMID:38494625 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Annie Jin Source Type: research
The Spread of STDs-A Preventable Public Health Crisis in the United States
Skinmed. 2024 Mar 18;22(1):11-13. eCollection 2024.NO ABSTRACTPMID:38494609 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Matthew Penna Theodore Rosen Source Type: research
DERM Author Taken to the Cleaners by a Reviewer: So, Do You Think the Reviewer of Your Submission Was Unkind? Read This
Skinmed. 2024 Mar 18;22(1):14-16. eCollection 2024.ABSTRACTHighly critical reviews of medical books are rarely encountered in our age, but this was not always the case. I provide an example of a very negative review of an early medical book that may have blocked the author from further publication.Papers published in reputable journals are subjected to review by experts, whose task is to find weakness in research and/or flaws in its arguments. Published reviews of textbooks that appear these days are generally laudatory, calling attention to the strengths of the book with little mention of any shortcomings. Non-meritorious...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Mark C Valentine Source Type: research
Monkeypox: What the Dermatologist Needs to Know
Skinmed. 2024 Mar 18;22(1):18-27. eCollection 2024.ABSTRACTMonkeypox, an endemic disease in some African countries, has provoked public health activeness on a global scale that even the World Health Organization (WHO), invoking international health regulations, declared it a public health emergency of international concern (PHEIC). The WHO called attention of member states to exert maximum surveillance over the disease, its patients, and contact persons in order to standardize control measures. A need was directed to provide complete knowledge about the disease, allowing the administration of prior diagnoses as well as iso...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Francisca Regina Oliveira Carneiro Egon Luiz Rodrigues Daxbacher Adilson DaCosta Heitor de S á Gonçalves Marcia Ramos-E-Silva Gerson Oliveira Penna Source Type: research
Cutaneous Metastases: Clinicopathologic Study of 30 Patients
Skinmed. 2024 Mar 18;22(1):30-34. eCollection 2024.ABSTRACTCutaneous metastases (CMs) of internal malignancies are uncommon. The breast in women and the lung in men represent the two elective sites of internal malignancies metastasizing to the skin. The aim of this study was to determine the epidemiologic, clinical, and pathologic features of CMs. A retrospective study of the patients diagnosed with CMs over 30 years was conducted. Thirty cases of CMs were enrolled in our study. In 16 cases (53%), the skin metastasis revealed the internal malignancy. The mean age was 66.4 years with sex ratio men/women of 2. CMs were solit...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Anissa Zaouak Wissal Ebdelli Malek Ben Slim ène Wael Smida Achraf Debbiche Selima Ben Jannet Houda Hammami Samy Fenniche Source Type: research
Effect of the Intralesional Forms of Methylprednisolone Acetate and Methotrexate on Psoriatic Nails
Skinmed. 2024 Mar 18;22(1):35-39. eCollection 2024.ABSTRACTIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.e., Depo-Medrol®) across individuals with nail psoriasis. We used a cohort study design, and both agents were administered intralesionally. Outcome variables were based on the Nail Psoriasis Severity Index (NAPSI). We quantified t...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Riad Kassem Aditya K Gupta Mary A Bamimore Mesbah Talukder Avner Shemer Lee Magal Anna Lyakhovitsky Ralph Daniel Baruch Kaplan Eran Galili Source Type: research
An Atlas of the Human Nail
Skinmed. 2024 Mar 18;22(1):41-47. eCollection 2024.ABSTRACTDermatologic literature describes nail abnormalities involving nail bed as linear erythronychia or onychomatricoma. The abnormality reflects cognitive content of the nail bed. A resourceful epidermis capable of manifesting in a variety of clinical appearances depends on initiating stimulus affecting remarkably its nail bed matrix cells. These cells are stem cells (NBMSC) migrating distally to cover remarkably the underlying nail bed dermal ridges that are homologous to finger print dermal ridges. Normally, adult nail bed epidermal cells are uniform and keratinize w...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Nardo Zaias Source Type: research
Tinea Amianacea: Attack of the Living Dead, Revisited
Skinmed. 2024 Mar 18;22(1):48-49. eCollection 2024.NO ABSTRACTPMID:38494615 (Source: Skinmed)
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Alyssa Swearington Rohan Shah Albert Alhatem Claude Gagna Muriel W Lambert Robert A Schwartz W Clark Lambert Source Type: research
