Falls from height in children: epidemiology and outcome
CONCLUSION: Our study shows that falls from windows of homes are an important cause of mortality. Height of fall was also an important predictor of morbidity that led to a higher level of hospitalisation care. Preventive measures should be implemented to ensure safety in high-rise residential buildings to prevent paediatric falls from heights.PMID:38363644 | DOI:10.4103/singaporemedj.SMJ-2021-397 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Kar Yee Catrin Kong Lai Peng Tham Source Type: research
Functional outcome of direct anterior versus posterior approach in total hip arthroplasty: a propensity-matched Asian study
CONCLUSION: In this study, patients who underwent DAA THA had better functional outcome at 2 years and almost 2 days shorter overall LOS than those who underwent PA THA. Therefore, the DAA to THA is a novel technique that has shown improved functional outcomes, with fewer complications compared to PA THA.PMID:38363645 | DOI:10.4103/singaporemedj.SMJ-2021-125 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Bryan Loh Akshay Padki Andy Yew Hee Nee Pang Source Type: research
Analysis of a preimplantation genetic test for aneuploidies in 893 screened blastocysts using KaryoLite BoBs: a single-centre experience
CONCLUSIONS: Blastocyst morphology, rate of development and maternal age were found to be significantly associated with euploidy rate. There is a trend that suggests PGT-A may help to improve the pregnancy rate, but it is not statistically different, and therefore, PGT-A remains an unproven hypothesis. Due to the limitation of a small size of the control group, further studies with more data are needed.PMID:38363646 | DOI:10.4103/singaporemedj.SMJ-2021-200 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Nai Qing Chen Cay Reen Si Shin Chyi Yung Sook Kit Hon Jayanthi Arasoo Soon-Chye Ng Source Type: research
Distilling lessons from home hospital implementation: a narrative scoping review
CONCLUSION: HaH presents a promising alternative care model, and many of the success factors identified, including the strong push for multidisciplinary single care teams, existing frameworks for data sharing and strong community network, are already present today. As such, Singapore appears to be well positioned to adopt a new care model like HaH.PMID:38363647 | DOI:10.4103/singaporemedj.SMJ-2020-478 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Shi Yin Wong Yao Neng Teo Yu Jun Wo Cher Wee Lim Yi Feng Lai Source Type: research
Increased left ventricular remodelling index in paradoxical low-flow severe aortic stenosis with preserved left ventricular ejection fraction compared to normal-flow severe aortic stenosis
CONCLUSION: Pathological LV remodelling (increased LVRI) was more common in patients with LF AS, and increased LVRI independently predicts worse clinical outcomes.PMID:38363650 | DOI:10.4103/singaporemedj.SMJ-2022-107 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Jinghao Nicholas Ngiam Nicholas Chew Eric Jou Jamie Sy Ho Thanawin Pramotedham Tze Sian Liong Ivandito Kuntjoro Tiong-Cheng Yeo Ching-Hui Sia William Kok Fai Kong Kian-Keong Poh Source Type: research
Approach to difficult-to-treat asthma in childhood: a narrative review
Singapore Med J. 2024 Feb 16. doi: 10.4103/singaporemedj.SMJ-2023-137. Online ahead of print.ABSTRACTAsthma is a major chronic disease affecting children, and children with difficult-to-treat asthma account for a disproportionate share of resource utilisation and healthcare costs. This review presents a comprehensive and up-to-date overview of the treatment strategies in difficult-to-treat paediatric asthma. Mimickers of asthma must first be ruled out, and the diagnosis confirmed with objective tests whenever possible. The effect of comorbid conditions such as obesity, smoking, other atopic conditions and psychosocial fact...
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Duo-Tong Cheng Liang Yi Justin Wee Oon Hoe Teoh Biju Thomas Source Type: research
An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore
CONCLUSIONS: The risk of myocarditis/pericarditis with mRNA vaccines was highest in adolescent males following Dose 2, and this was higher than historically observed background rates. Most cases were clinically mild. The risk of myocarditis should be weighed against the benefits of receiving an mRNA vaccine, keeping in mind that SARS-CoV-2 infections carry substantial risks of myocarditis/pericarditis, as well as the evolving landscape of the disease.PMID:38363732 | DOI:10.4103/singaporemedj.SMJ-2023-089 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Mun Yee Tham Cheng Leng Chan Dorothy Toh Jalene Poh Adena Lim Sally Soh Li Fung Peck Belinda Foo Amelia Ng Patricia Ng Pei San Ang Sreemanee Dorajoo Desmond Teo Toon Wei Lim Yean Teng Lim Jonathan Choo Zee Pin Ding Khung Keong Yeo Jonathan Yap Hui Xing Ta Source Type: research
Obstructive sleep apnoea and nocturnal atrial fibrillation in patients with ischaemic heart disease
CONCLUSION: In patients with IHD, there was a significant association between severe OSA and nocturnal AF/flutter. This underscores the need to evaluate for OSA in patients with IHD, as it may have important implications on clinical outcomes.PMID:38363738 | DOI:10.4103/singaporemedj.SMJ-2021-293 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Silin Kuang Yiong Huak Chan Serene Wong See Meng Khoo Source Type: research
Falls from height in children: epidemiology and outcome
CONCLUSION: Our study shows that falls from windows of homes are an important cause of mortality. Height of fall was also an important predictor of morbidity that led to a higher level of hospitalisation care. Preventive measures should be implemented to ensure safety in high-rise residential buildings to prevent paediatric falls from heights.PMID:38363644 | DOI:10.4103/singaporemedj.SMJ-2021-397 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Kar Yee Catrin Kong Lai Peng Tham Source Type: research
Functional outcome of direct anterior versus posterior approach in total hip arthroplasty: a propensity-matched Asian study
CONCLUSION: In this study, patients who underwent DAA THA had better functional outcome at 2 years and almost 2 days shorter overall LOS than those who underwent PA THA. Therefore, the DAA to THA is a novel technique that has shown improved functional outcomes, with fewer complications compared to PA THA.PMID:38363645 | DOI:10.4103/singaporemedj.SMJ-2021-125 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Bryan Loh Akshay Padki Andy Yew Hee Nee Pang Source Type: research
Analysis of a preimplantation genetic test for aneuploidies in 893 screened blastocysts using KaryoLite BoBs: a single-centre experience
CONCLUSIONS: Blastocyst morphology, rate of development and maternal age were found to be significantly associated with euploidy rate. There is a trend that suggests PGT-A may help to improve the pregnancy rate, but it is not statistically different, and therefore, PGT-A remains an unproven hypothesis. Due to the limitation of a small size of the control group, further studies with more data are needed.PMID:38363646 | DOI:10.4103/singaporemedj.SMJ-2021-200 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Nai Qing Chen Cay Reen Si Shin Chyi Yung Sook Kit Hon Jayanthi Arasoo Soon-Chye Ng Source Type: research
Distilling lessons from home hospital implementation: a narrative scoping review
CONCLUSION: HaH presents a promising alternative care model, and many of the success factors identified, including the strong push for multidisciplinary single care teams, existing frameworks for data sharing and strong community network, are already present today. As such, Singapore appears to be well positioned to adopt a new care model like HaH.PMID:38363647 | DOI:10.4103/singaporemedj.SMJ-2020-478 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Shi Yin Wong Yao Neng Teo Yu Jun Wo Cher Wee Lim Yi Feng Lai Source Type: research
Increased left ventricular remodelling index in paradoxical low-flow severe aortic stenosis with preserved left ventricular ejection fraction compared to normal-flow severe aortic stenosis
CONCLUSION: Pathological LV remodelling (increased LVRI) was more common in patients with LF AS, and increased LVRI independently predicts worse clinical outcomes.PMID:38363650 | DOI:10.4103/singaporemedj.SMJ-2022-107 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Jinghao Nicholas Ngiam Nicholas Chew Eric Jou Jamie Sy Ho Thanawin Pramotedham Tze Sian Liong Ivandito Kuntjoro Tiong-Cheng Yeo Ching-Hui Sia William Kok Fai Kong Kian-Keong Poh Source Type: research
Approach to difficult-to-treat asthma in childhood: a narrative review
Singapore Med J. 2024 Feb 16. doi: 10.4103/singaporemedj.SMJ-2023-137. Online ahead of print.ABSTRACTAsthma is a major chronic disease affecting children, and children with difficult-to-treat asthma account for a disproportionate share of resource utilisation and healthcare costs. This review presents a comprehensive and up-to-date overview of the treatment strategies in difficult-to-treat paediatric asthma. Mimickers of asthma must first be ruled out, and the diagnosis confirmed with objective tests whenever possible. The effect of comorbid conditions such as obesity, smoking, other atopic conditions and psychosocial fact...
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Duo-Tong Cheng Liang Yi Justin Wee Oon Hoe Teoh Biju Thomas Source Type: research
An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore
CONCLUSIONS: The risk of myocarditis/pericarditis with mRNA vaccines was highest in adolescent males following Dose 2, and this was higher than historically observed background rates. Most cases were clinically mild. The risk of myocarditis should be weighed against the benefits of receiving an mRNA vaccine, keeping in mind that SARS-CoV-2 infections carry substantial risks of myocarditis/pericarditis, as well as the evolving landscape of the disease.PMID:38363732 | DOI:10.4103/singaporemedj.SMJ-2023-089 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - February 16, 2024 Category: General Medicine Authors: Mun Yee Tham Cheng Leng Chan Dorothy Toh Jalene Poh Adena Lim Sally Soh Li Fung Peck Belinda Foo Amelia Ng Patricia Ng Pei San Ang Sreemanee Dorajoo Desmond Teo Toon Wei Lim Yean Teng Lim Jonathan Choo Zee Pin Ding Khung Keong Yeo Jonathan Yap Hui Xing Ta Source Type: research
