Preventing perioperative hypothermia in children through implementation of customised guidelines
CONCLUSIONS: Customised guidelines facilitated a sustained reduction of hypothermia in our paediatric surgical patients, although its impact was reduced by cost considerations.PMID:38478735 | DOI:10.4103/singaporemedj.SMJ-2023-021 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Shu Ying Lee Rehena Sultana John Carson Allen Choon Looi Bong Source Type: research
HER2-low breast cancers: challenges in the interpretation of immunohistochemistry
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-037. Online ahead of print.ABSTRACTOverexpression of human epidermal growth factor receptor 2 (HER2) protein in breast cancers carries significant prognostic and therapeutic implications. Anti-HER2 blockade has shown to be a useful adjunct to surgery in treating HER2-positive tumours. Up till today, the HER2 immunohistochemistry (IHC) and in situ hybridisation (ISH) scoring algorithms are geared towards identifying HER2-positive cases. A recently published Phase III clinical trial (DESTINY-Breast04) has demonstrated that an antibody-drug conjugate (trastuzum...
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Noel Chia Mihir Ananta Gudi Emad Rakha Puay Hoon Tan Source Type: research
Association of postpartum depression with child growth and developmental outcomes: a community-based study
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-107. Online ahead of print.NO ABSTRACTPMID:38478737 | DOI:10.4103/singaporemedj.SMJ-2023-107 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Moira Suyin Chia Nur Adila Binte Ahmad Hatib Elaine Chu Shan Chew Shu-Ling Chong Rehena Sultana Ade Xin Ning Tan Xiaoxuan Guo David Chee Chin Ng Padmini Sita Yeleswarapu Pratibha Keshav Agarwal Helen Yu Chen Yoke Hwee Chan Source Type: research
Diagnostic threshold and performance of anion gap in screening for high anion gap metabolic acidosis
CONCLUSION: The recommended AG threshold value is ≥15 mEq/L with a high sensitivity for HAGMA. The AG should always be interpreted with the clinical context, and it should be repeated as the clinical picture evolves.PMID:38478728 | DOI:10.4103/singaporemedj.SMJ-2023-009 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Chang Yin Chionh Carolyn Shan-Yeu Tien Wenxiang Yeon Changi REnal MEdicine REsearch (CREMERE) Group Source Type: research
Disaster medicine in Singapore: past, present, future
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-019. Online ahead of print.NO ABSTRACTPMID:38478733 | DOI:10.4103/singaporemedj.SMJ-2023-019 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Li Juan Joy Quah Jen Heng Pek Lenard Cheng Chan Yu Lee David Kuan Peng Teng Mathew Yi Wen Yeo Venkataraman Anantharaman Source Type: research
Preventing perioperative hypothermia in children through implementation of customised guidelines
CONCLUSIONS: Customised guidelines facilitated a sustained reduction of hypothermia in our paediatric surgical patients, although its impact was reduced by cost considerations.PMID:38478735 | DOI:10.4103/singaporemedj.SMJ-2023-021 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Shu Ying Lee Rehena Sultana John Carson Allen Choon Looi Bong Source Type: research
HER2-low breast cancers: challenges in the interpretation of immunohistochemistry
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-037. Online ahead of print.ABSTRACTOverexpression of human epidermal growth factor receptor 2 (HER2) protein in breast cancers carries significant prognostic and therapeutic implications. Anti-HER2 blockade has shown to be a useful adjunct to surgery in treating HER2-positive tumours. Up till today, the HER2 immunohistochemistry (IHC) and in situ hybridisation (ISH) scoring algorithms are geared towards identifying HER2-positive cases. A recently published Phase III clinical trial (DESTINY-Breast04) has demonstrated that an antibody-drug conjugate (trastuzum...
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Noel Chia Mihir Ananta Gudi Emad Rakha Puay Hoon Tan Source Type: research
Association of postpartum depression with child growth and developmental outcomes: a community-based study
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-107. Online ahead of print.NO ABSTRACTPMID:38478737 | DOI:10.4103/singaporemedj.SMJ-2023-107 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Moira Suyin Chia Nur Adila Binte Ahmad Hatib Elaine Chu Shan Chew Shu-Ling Chong Rehena Sultana Ade Xin Ning Tan Xiaoxuan Guo David Chee Chin Ng Padmini Sita Yeleswarapu Pratibha Keshav Agarwal Helen Yu Chen Yoke Hwee Chan Source Type: research
Clinical outcomes of variceal and non-variceal upper gastrointestinal bleeding in cirrhosis patients in Singapore
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2023-046. Online ahead of print.NO ABSTRACTPMID:38444185 | DOI:10.4103/singaporemedj.SMJ-2023-046 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Garrett Kang Le Shaun Ang Wen Hui Leia Teo Yu Wei Cheryl Huang Venkataraman Narayan Andrew Boon Eu Kwek Tiing Leong Ang Yu Jun Wong Source Type: research
Fitness to drive after trigger or carpal tunnel release surgery: perceptions of patients versus clinicians
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2021-424. Online ahead of print.NO ABSTRACTPMID:38449071 | DOI:10.4103/singaporemedj.SMJ-2021-424 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Camelia Qian Ying Tang Sean Han Sheng Lai Ellen Yutan Lee Anthony Foo Alphonsus Khin Sze Chong Source Type: research
Prehospital stroke care in Singapore
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2023-066. Online ahead of print.ABSTRACTDue to the narrow window of opportunity for stroke therapeutics to be employed, effectiveness of stroke care systems is predicated on the efficiency of prehospital stroke systems. A robust prehospital stroke system of care that provides a rapid and well-coordinated response maximises favourable poststroke outcomes, but achieving this presents a unique set of challenges dependent on demographic and geographical circumstances. Set in the context of a highly urbanised first-world nation with a rising burden of stroke, Singapore...
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Timothy Jia Rong Lam Zhenghong Liu Benjamin Yong-Qiang Tan Yih Ying Ng Colin Kaihui Tan Xiang Yi Wong Narayanaswamy Venketasubramanian Leonard Leong Litt Yeo Andrew Fu Wah Ho Marcus Eng Hock Ong Source Type: research
Use of wearable technology in cardiac monitoring after cryptogenic stroke or embolic stroke of undetermined source: a systematic review
CONCLUSION: Wearable devices that are ECG or PPG based are effective for paroxysmal AF detection after cryptogenic stroke and ESUS, but further studies are needed to establish how they compare with Holter monitors and implantable loop recorder.PMID:38449074 | DOI:10.4103/singaporemedj.SMJ-2022-143 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Jamie Sy Ho Elizabeth Sy Ho Leonard Ll Yeo William Kf Kong Tony Yw Li Benjamin Yq Tan Mark Y Chan Vijay K Sharma Kian-Keong Poh Ching-Hui Sia Source Type: research
Clinical outcomes of variceal and non-variceal upper gastrointestinal bleeding in cirrhosis patients in Singapore
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2023-046. Online ahead of print.NO ABSTRACTPMID:38444185 | DOI:10.4103/singaporemedj.SMJ-2023-046 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Garrett Kang Le Shaun Ang Wen Hui Leia Teo Yu Wei Cheryl Huang Venkataraman Narayan Andrew Boon Eu Kwek Tiing Leong Ang Yu Jun Wong Source Type: research
Fitness to drive after trigger or carpal tunnel release surgery: perceptions of patients versus clinicians
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2021-424. Online ahead of print.NO ABSTRACTPMID:38449071 | DOI:10.4103/singaporemedj.SMJ-2021-424 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Camelia Qian Ying Tang Sean Han Sheng Lai Ellen Yutan Lee Anthony Foo Alphonsus Khin Sze Chong Source Type: research
Prehospital stroke care in Singapore
Singapore Med J. 2024 Mar 6. doi: 10.4103/singaporemedj.SMJ-2023-066. Online ahead of print.ABSTRACTDue to the narrow window of opportunity for stroke therapeutics to be employed, effectiveness of stroke care systems is predicated on the efficiency of prehospital stroke systems. A robust prehospital stroke system of care that provides a rapid and well-coordinated response maximises favourable poststroke outcomes, but achieving this presents a unique set of challenges dependent on demographic and geographical circumstances. Set in the context of a highly urbanised first-world nation with a rising burden of stroke, Singapore...
Source: Singapore Medical Journal - March 6, 2024 Category: General Medicine Authors: Timothy Jia Rong Lam Zhenghong Liu Benjamin Yong-Qiang Tan Yih Ying Ng Colin Kaihui Tan Xiang Yi Wong Narayanaswamy Venketasubramanian Leonard Leong Litt Yeo Andrew Fu Wah Ho Marcus Eng Hock Ong Source Type: research
