What's New in Shock, December 2021?
No abstract available (Source: Shock)
Source: Shock - November 26, 2021 Category: Emergency Medicine Tags: Commentary Source Type: research
Neutrophil-to-Lymphocyte Ratio and Covid-19
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Reply Letter to The Editor Regarding: Cytokine Drizzle—The Rationale for Abandoning The Term Cytokine Storm
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Septic Shock Had the Highest Concentrations of Cytokines, Yet Patients With Autoimmune Diseases have Very Low Blood Levels of Cytokines, But Dramatically Respond to Cytokine Inhibitors: How Should We Really Look at This?
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Reply to The Letter to The Editor: Adipocyte Browning in Response to Trauma: Some Important Methodological Considerations
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Adipocyte Browning in Response to Trauma: Some Important Methodological Considerations
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Author's Response: Abrupt Discontinuation Versus Down-Titration of Vasopressin in Patients Recovering from Septic Shock
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Abrupt Discontinuation Versus Down-Titration of Vasopressin in Patients Recovering from Septic Shock
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
Assessment of Inhaled Hydrogen Sulfide in Suppressing Deterioration in Patients With COVID-19
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Letters to the Editor Source Type: research
H2S as a Therapeutic Adjuvant Against COVID-19: Why and How?
No abstract available (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Invited Opinion Source Type: research
Brain and Myocardial Mitochondria Follow Different Patterns of Dysfunction After Cardiac Arrest
In conclusion, the kinetics of cardiac and cerebral mitochondrial dysfunction suggests that mitochondrial function does not play a major role in the early phase of the post-resuscitation process but is only involved in the longer pathophysiological events. (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
Noninvasive Beat-To-Beat Stroke Volume Measurements to Determine Preload Responsiveness During Mini-Fluid Challenge in a Swine Model: A Preliminary Study
The objectives of this paper are to compare EIT with an invasive pulse contour analysis (PCA) method in measuring SV during mini-fluid challenge in animals and determine preload responsiveness with EIT. Five pigs were anesthetized and mechanically ventilated. After removing 25% to 30% of the total blood from each animal, multiple fluid injections were conducted. The EIT device successfully tracked changes in SV beat-to-beat during varying volume states, i.e., from hypovolemia and preload responsiveness to target volume and volume overload. From a total of 50 100-mL fluid injections on five pigs (10 injections per pig), the...
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
NLRP3 Inflammasome Mediates Neurodegeneration in Rats with Chronic Neuropathic Pain
Patients with chronic neuropathic pain (NP) have a significantly increased risk of central nervous degeneration. Trigeminal neuralgia (TN) is a typical NP, and this manifestation is more obvious. In addition to severe pain, patients with TN are often accompanied by cognitive dysfunction and have a higher risk of central nervous system degeneration, but the mechanism is not clear. The NOD-like receptor 3 (NLRP3) inflammasome assembles inside of microglia on activation, which plays an important role in neurodegeneration such as Alzheimer disease. MCC950 is a specific blocker of NLRP3 inflammasome, which can improve the perfo...
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
Vagus Nerve Stimulation Protects Enterocyte Glycocalyx After Hemorrhagic Shock Via the Cholinergic Anti-Inflammatory Pathway
Introduction:
Electrical vagal nerve stimulation is known to decrease gut permeability and alleviate gut injury caused by traumatic hemorrhagic shock. However, the specific mechanism of action remains unclear. Glycocalyx, located on the surface of the intestinal epithelium, is associated with the buildup of the intestinal barrier. Therefore, the goal of our study was to explore whether vagal nerve stimulation affects enterocyte glycocalyx, gut permeability, gut injury, and remote lung injury.
Materials and methods:
Male Sprague Dawley rats were anesthetized and their cervical nerves were exposed. The rats underw...
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
Therapeutic Methods for Gut Microbiota Modification in Lipopolysaccharide-Associated Encephalopathy
Conclusion:
Among the four methods, fecal microbiota transplantation was the most useful method to modify the dysbiosis of intestinal microbiota and improve brain function in septic rats. These findings reveal the protective consequence of microbiota modification, and the findings suggest opportunities to improve brain function in sepsis. (Source: Shock)
Source: Shock - October 21, 2021 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
