Anal and oral detection of Treponema pallidum in men who have sex with men with early syphilis infection
Conclusions These data suggest T. pallidum load at the anus is higher than at the oral cavity and that a subset of men with secondary syphilis and prolonged anal lesions may be relatively infectious. Earlier detection and treatment of syphilis, when RPR titres are lower than 1:16, could potentially reduce infectiousness from anal and oral sites. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - November 17, 2022 Category: Sexual Medicine Authors: Towns, J. M., Chow, E. P. F., Wigan, R., Fairley, C. K., Williamson, D., Azzato, F., Graves, S., Zhang, L., Chen, M. Y. Tags: Original research Source Type: research

Shigella is common in symptomatic and asymptomatic men who have sex with men visiting a sexual health clinic in Amsterdam
Conclusion Shigella infections are relatively common in both symptomatic and asymptomatic MSM. Future studies should focus on the risk of onward transmission via asymptomatic persons. Samenvatting Introductie Shigellose is een meldingsplichtige infectieziekte. Het kan zich presenteren als een ernstige bloederige diarree, maar is vaak asymptomatisch. Shigella kan seksueel overdraagbaar zijn. We hebben een onderzoek uitgevoerd onder symptomatische en asymptomatische mannen die seks hebben met mannen (MSM) om de prevalentie van Shigella, Salmonella en Campylobacter te bepalen. Methoden Van maart tot juni 2020 werden ac...
Source: Sexually Transmitted Infections - November 17, 2022 Category: Sexual Medicine Authors: Braam, J. F., Bruisten, S. M., Hoogeland, M., de Vries, H. J. C., Schim van der Loeff, M. F., van Dam, A. P. Tags: Editor's choice Original research Source Type: research

Social networks, high-risk anal HPV and coinfection with HIV in young sexual minority men
Conclusions Networked patterns of hrHPV infection could be amenable to network-based HPV prevention interventions that engage young SMM of predominantly racial minority groups who are out of HIV care and vulnerable to high-risk HPV acquisition. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - November 17, 2022 Category: Sexual Medicine Authors: Fujimoto, K., Nyitray, A. G., Kuo, J., Zhao, J., Hwang, L.-Y., Chiao, E., Giuliano, A. R., Schneider, J. A., Khanna, A. Tags: Original research Source Type: research

Chemsex and incidence of sexually transmitted infections among Canadian pre-exposure prophylaxis (PrEP) users in the lActuel PrEP Cohort (2013-2020)
Conclusion Among PrEP users, chemsex at baseline was linked to increased incidence of gonorrhoea and chlamydia. This effect was stronger for people reporting multiple chemsex substances. The high STI incidence among gbMSM who report chemsex highlights the importance of PrEP for this population and the need for integrated services that address the complexities of sexualised substance use. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - November 17, 2022 Category: Sexual Medicine Authors: Flores Anato, J. L., Panagiotoglou, D., Greenwald, Z. R., Blanchette, M., Trottier, C., Vaziri, M., Charest, L., Szabo, J., Thomas, R., Maheu-Giroux, M. Tags: Open access Original research Source Type: research

Research news in clinical context
Syphilis cases are concentrated in three men who have sex with men (MSM) population groups in Europe: PrEP (Pre-Exposure Prophylaxis) users, sex workers and people living with HIV In this two-wave web-based survey of European MSM (n=278 256 participants across 31 countries), the proportion of respondents self-reporting a syphilis diagnosis in the previous 12 months rose from 2.3% in 2010 to 4.5% in 2017. In adjusted analyses, factors associated with a syphilis diagnosis comprised STI screening in the previous month versus no screening (adjusted OR (aOR) 25.76), HIV PrEP use (aOR 3.02), living with HIV (aOR 2.67), selling s...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Rusconi, S., Tan, R. K. J., Ceccherini-Silberstein, F. Tags: Perspectives Source Type: research

STASHH: reflections and aspirations
Founded in spring 2021, the Student and Trainee Association for Sexual Health and HIV (STASHH) aims to improve recruitment to genitourinary medicine (GUM) through facilitation and provision of clinical and academic opportunities for medical students (MSs) and prespecialty doctors (PSDs). STASHH employs four pillars to achieve its aims: education, mentoring, recruitment and projects.1 2 STASHH provides monthly educational webinars showcasing the breadth of specialised services delivered under the umbrella of GUM. Evaluation of the first five webinars suggests they have been well received, with an average of 140 sign-ups and...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: McMahon, B. L., Selwyn, B. L., Todd, L.-I., Cochrane, E. Tags: BASHH column Source Type: research

Changes in the notification of HIV diagnoses during the COVID-19 pandemic in Peru
We report a decline in the reporting of HIV diagnoses in Peru throughout the COVID-19 pandemic. In 2020, 5170 HIV diagnoses were reported in Peru, representing a 33% decrease in the average number of HIV diagnoses between 2017 and 2019 (n=7746). At a regional level, the median number of HIV diagnoses reported in 2017–2019 was 139 (IQR 77–311) and in 2020 was 114 (IQR 60–157) (p≤0.001). Twenty-one of 25 regions reported a decrease in HIV diagnoses in 2020 compared with 2017–2019. Regions in the north of Peru showed the largest decrease in the number of HIV diagnoses (figure 1). Figure 1Notificatio...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Paredes, J. L., Owen, R., Mejia, F. Tags: COVID-19 PostScript Source Type: research

Antibiotic resistance among sexually transmitted infections: perspectives from clinical practice
We present two cases of men who have sex with men (MSM) in care at the Infectious Diseases Unit, San Raffaele Hospital, Milan diagnosed with multidrug-resistant (MDR) STIs. Both presented with complaints of urethral discharge and were engaged in receptive/insertive sexual intercourse with >10 partners monthly, with seldom condom use. The first case is an injecting-drug user with history of hepatitis B and C virus coinfection diagnosed in 2013 with ceftriaxone-resistant Neisseria gonorrhoeae (NG) proctitis, and ciprofloxacin-resistant and azithromycin-resistant Ureaplasma urealyticum (UU) and Chlamydia trachomatis (CT) u...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Raccagni, A. R., Bruzzesi, E., Cernuschi, M., Galli, L., Alberton, F., Mancini, N., Castagna, A., Nozza, S. Tags: PostScript Source Type: research

Exploring the effectiveness of an online sexual health workshop on sexual and relationship beliefs and HIV/STI prevention knowledge among Singaporean youth
In Singapore, sexual education programmes have traditionally placed strong focus on abstinence1; however, abstinence-only sexual education has shown to be ineffective in other settings.2 Here, we report on an online sexual health education workshop targeted to Singapore citizens or permanent residents 18–29 years old who identified as either women, heterosexual men, or gay, bisexual and queer (GBQ) men. Participants were targeted through the community-based organisation, Action for AIDS Singapore’s mailing list, and were able to register their interest for the workshop through an enrolment survey embedded in th...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Yong, X. M., Banerjee, S., Lin, J., Nah, T., Tan, M., Tyler, A., Tong, F. Y., Tan, R. K. J. Tags: Research letter Source Type: research

Trichoscopy of syphilitic alopecia: a systematic review
To the Editor: Secondary syphilis may manifest as syphilitic alopecia (SA), a non-scarring alopecia with a prevalence ranging from 3% to 22%.1 Examination of the hair using a dermatoscope, a non-invasive bedside test known as trichoscopy, may help differentiate SA from other forms of hair loss.2 3 This systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to summarise published data on trichoscopic findings of SA (PROSPERO CRD42018092159). Details of the searches (from inception to 22 April 2021), study selection, data extraction and quality assessment are provided in and ...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Sun, H. Y., Wong, X. L., Chen, M. K. Y., Sebaratnam, D. F. Tags: Research letter Source Type: research

COVID-19 impact on bacterial sexually transmitted infections in England between 1 January 2019 and 31 December 2020
The COVID-19 pandemic has disrupted the delivery of healthcare services, including sexual health services (SHS) in England. Many SHS remained open for urgent or complex cases, but at reduced capacity; meanwhile, the use of online and telephone services increased to meet the continued demand for STI services.1 We compared trends in testing and diagnoses for bacterial STIs in England throughout different periods of COVID-19 restrictions during 2020 with the equivalent prepandemic data for 2019. National data for England on tests and diagnoses for chlamydia, gonorrhoea and syphilis (primary, secondary and early latent stages)...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Charles, H., Ratna, N., Thorn, L., Sonubi, T., Sun, S., Mohammed, H., Folkard, K., Sinka, K. Tags: Open access, COVID-19 Research letter Source Type: research

Increasing human papilloma virus (HPV) vaccination uptake in people living with HIV: the need to improve both clinician training and health promotion
Human papilloma virus (HPV) vaccination is recommended for some people living with HIV (PLWHIV) including men who have sex with men (MSM) up to 45 years old.1 HIV clinics are well placed to deliver HPV vaccination due to patients’ regular attendance for routine monitoring and other health interventions. There is little recent evidence on the uptake and barriers to HPV vaccination in PLWHIV.2 A recent meta-analysis suggested that MSM are receptive to HPV vaccination, but vaccine uptake and completion are below prediction, and additional support and resources are needed to provide optimal vaccination rates.3 Uptake of ...
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Ringshall, M., Cable, C., Fitzpatrick, C., Richardson, D. Tags: Research letter Source Type: research

Access to, usage and clinical outcomes of, online postal sexually transmitted infection services: a scoping review
Conclusion OPSS services appear highly acceptable to users. However, uptake appears to be socially patterned and some groups who bear a disproportionate burden of poor sexual health in the UK are under-represented among users. Current provision of online self-sampling could widen health inequalities, particularly where other options for testing are limited. Work is needed to fully evaluate the impact and cost-effectiveness of OPSS services. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Sumray, K., Lloyd, K. C., Estcourt, C. S., Burns, F., Gibbs, J. Tags: Open access Review Source Type: research

Changes in the time of COVID-19: a quality improvement initiative to maintain services at a youth sexual health clinic
Conclusions Quality improvement PDSA initiatives at AYA sexual health clinics, particularly those for underserved youth, can be used to adapt service delivery when normal operating models are disrupted. The ability for youth sexual health clinics to adapt to a changing healthcare landscape will be crucial in ensuring that under-resourced youth are able to receive needed services and ambitious Ending the HIV Epidemic goals are achieved. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Lim, A. C., Venkatesh, M., Lewald, D. L., Emmanuel, P. J., Sanders, L. Tags: COVID-19 Short reports Source Type: research

Factors associated with low levels of HIV testing among young men who have sex with men (MSM) participating in EMIS-2017 in Spain
Conclusion Young MSM showed low HIV testing rate. Future programming specifically targeting this population, especially those middle adolescents, living in a medium-small city and having less ‘outness’, can help increase HIV testing and prevent access barriers. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - October 21, 2022 Category: Sexual Medicine Authors: Gallego, N., Diaz, A., Folch, C., Meyer, S., Vazquez, M., Casabona, J., Hernando, V. Tags: Original research Source Type: research