Syphilitic Spinal Disease: An Old Nemesis Revisited. A Case Series and Review of Literature
We report 3 challenging cases of syphilitic spinal disease presenting as myelopathy—1 with an extra-axial gumma of tertiary syphilis causing cord compression and 2 with tabes dorsalis complicated by tabetic spinal neuroarthropathy—each presenting a diagnostic dilemma to their treating physicians. We also review the literature for updates on modern investigative modalities and discuss pitfalls physicians need to avoid to arrive at the diagnosis. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Case Reports Source Type: research
Congenital Syphilis: A Case Report Demonstrating Missed Opportunities for Screening and Inadequate Treatment Despite Multiple Health Care Encounters During Pregnancy
A case of congenital syphilis due to multiple missed opportunities, highlights the challenges of treating syphilis during pregnancy. Although cases are increasing in the United States, congenital syphilis, a disease with devastating consequences, is preventable. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Case Reports Source Type: research
Universal Prenatal Screening and Testing and Chlamydia trachomatis Conjunctivitis in Infants
We retrospectively reviewed all infant Chlamydia trachomatis eye cultures submitted to the Chlamydia Research Laboratory from 1986 to 2002. The positivity rate was 15.6% during the period before the implementation of universal prenatal screening (1986–1993) compared with 1.8% during the screening period (1994–2002). (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Note Source Type: research
Sexual Behavior Surveys Should Ask More: Covering the Diversity of Sexual Behaviors That May Contribute to the Transmission of Pathogens
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Commentary Source Type: research
Human Papillomavirus Vaccine to End Oropharyngeal Cancer. A Systematic Review and Meta-Analysis
Oropharyngeal cancer (OPC) is currently the most frequent human papillomavirus (HPV)–related malignancy in high-income countries. Oral HPV16 infection is the cause of HPV-related OPC in more than 90% of cases and is primarily (90%) linked to oral sex. This systematic review and meta-analysis aimed at comparing the prevalence of oral vaccine–type HPV infection in individuals vaccinated with HPV vaccines and unvaccinated controls. Three databases (MEDLINE, ScienceDirect, and the Cochrane Library), as well as other sources, were searched by 2 independent reviewers. Controlled studies testing the efficacy or effectiveness ...
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Review Source Type: research
Predictors of Human Papillomavirus Seropositivity in Appalachian Women Aged 18 to 26 Years
Conclusions
Both HPV infection and vaccine-related HPV type seropositivity is common among Appalachian women aged 18 to 26 years. The anticipated effect of environmental stressors on HPV seropositivity was not seen when multiple predictors were considered. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Human Immunodeficiency Virus Preexposure Prophylaxis Knowledge, Attitudes and Perceptions of Sexual Health Risk in an Age of Sexually Transmitted Infection Antimicrobial Resistance
Conclusions
The PrEP awareness was high, but purchase cost limited access. PrEP may increase condomless anal intercourse, but interviewees used PrEP as one of many risk-reduction tools. Reduced fear of HIV transmission and testing was highly valued. Sexually transmitted infection AMR was not seen as an immediate threat and did not influence risk perception or sexual decision making. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
High Prevalence of Macrolide and Fluoroquinolone Resistance–Mediating Mutations in Mycoplasma genitalium–Positive Urine Specimens From Saskatchewan
Background
Mycoplasma genitalium is an emerging, sexually transmitted infection, which is more prevalent than Chlamydia trachomatis in some regions. An increase in antibiotic resistance, that is, azithromycin and moxifloxacin, recommended for treating M. genitalium infections has been noted. This is the first detailed report on the prevalence of M. genitalium and its antimicrobial resistance in Saskatchewan, Canada.
Methods
Aptima urine specimens (n = 1977), collected for the diagnosis of C. trachomatis/Neisseria gonorrhoeae, were tested for M. genitalium using the Aptima M. genitalium assay (MG-TMA). Antimicrob...
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Limited Utility of Reverse Algorithm Syphilis Testing in HIV Clinic Among Men Who Have Sex With Men
Conclusions
Among men who have sex with men tested in HIV clinic, the syphilis reverse algorithm was inefficient because of high rates of prior syphilis and false-positive EIA screening. Frequent syphilis screening in high-prevalence populations is an important part of the US epidemic response, and the traditional algorithm is preferred. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
A Comparison of Treponema pallidum Subspecies pallidum Molecular Typing Systems: Multilocus Sequence Typing vs. Enhanced Centers for Disease Control and Prevention Typing
Conclusions
Compared with ECDCT, MLST was not uniformly more discriminating. Both typing systems demonstrate that specific types may be more neurotropic than others. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
The Estimated Impact of Implementing a Funding Allocation Formula on the Number of Gonorrhea Cases in the United States, 2014 to 2018
Conclusions
By shifting resources toward jurisdictions with greater disease burden, the funding formula averted a substantial number of gonorrhea cases at no additional cost. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
HIV Prevention and Treatment Cascades Among Female Sex Workers in Benin, West Africa
Background
Benin has a long-standing history of HIV prevention programs aimed at female sex workers (FSWs). We used data from a national survey among FSWs (2017) to assess the prevention and care cascades in this population.
Methods
Female sex workers were recruited through cluster sampling of sex work sites. A questionnaire was administered, and HIV tested. HIV-positive participants were asked to provide dried blood spots and were tested for antiretroviral and viral load. We assessed 2 prevention cascades (HIV testing and safer sex) and the treatment cascade, using a combination of self-reported and biological ...
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Structural and Environmental Influences Increase the Risk of Sexually Transmitted Infection in a Sample of Female Sex Workers
Conclusions
More than a quarter of FSWs had confirmed chlamydia or gonorrhea. In addition to STI risks at the individual level, STIs are driven by structural vulnerabilities. Results point to a number of salient factors to be targeted in STI prevention among FSWs. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Extragenital Screening of Chlamydia trachomatis and Neisseria gonorrhoeae Among Women in the College Health Setting
Conclusions
Nearly 1 of 22 CT infections and nearly 1 of 3 GC infections would have been missed without extragenital screening in this analysis of college women. Inclusion of risk-prompted extragenital screening in asymptomatic STD screening protocols can help clinicians diagnose CT and GC infections that would be have been missed with urogenital-only screening. Although rectal GC infections among women seem to be less common, oropharyngeal testing, in particular, for GC is suggested for women based on sexual risk. However, clinicians might only identify these risks if they ask patients directly about these potential e...
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Impacts of Changing Sexual Behavior on Chlamydia and Gonorrhea Burden Among US High School Students, 2007 to 2017
Conclusions
Whatever its origins, changing sexual behavior among adolescents results in large estimated reductions in STI burden and medical costs relative to previous cohorts. Although diagnoses among adolescents have not declined at this rate, multiple explanations could make these apparently divergent trends consistent. Efforts to continue supporting effective sex education in and out of school along with STI screening for adolescents should reinforce these gains. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - August 19, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
