Seminars in Thrombosis and Hemostasis Seminars in Thrombosis and Hemostasis RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

10-Year Evolution in Worldwide Usage of Anticoagulant Drugs
Semin Thromb Hemost DOI: 10.1055/s-0042-1756702 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 29, 2022 Category: Hematology Authors: Lippi, Giuseppe Mattiuzzi, Camilla Favaloro, Emmanuel J. Tags: Letter to the Editor Source Type: research

The Case for Therapeutic-Intensity Anticoagulation in Patients with COVID-19-Associated Moderate Illness
Semin Thromb Hemost DOI: 10.1055/s-0042-1756709 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 29, 2022 Category: Hematology Authors: Cuker, Adam Tags: Commentary Source Type: research

Diagnostic Testing for von Willebrand Disease: Trends and Insights from North American Laboratories over the Last Decade
In this report, NASCOLA EQA data from 2010 to 2021 are reviewed for trends in methodology and precision among various assays. In particular, recent ASH ISTH NHF WFH (American Society of Hematology, International Society on Thrombosis and Haemostasis, National Hemophilia Foundation, and World Hemophilia Federation) guidelines for diagnosis of VWD are reviewed in light of EQA data. In contrast to other geographic regions, laboratories in North America predominantly use three-assay screening panels (antigen, platelet-binding activity, and factor VIII [FVIII] activity) rather than four-assay panels (antigen, platelet-binding a...
Source: Seminars in Thrombosis and Hemostasis - September 19, 2022 Category: Hematology Authors: Ziemba, Yonah C. Abdulrehman, Jameel Hollestelle, Martine J. Meijer, Piet Plumhoff, Elizabeth Hsu, Peihong Selby, Rita Tags: Review Article Source Type: research

Advances in the Management of Coagulopathy in Trauma: The Role of Viscoelastic Hemostatic Assays across All Phases of Trauma Care
Semin Thromb Hemost DOI: 10.1055/s-0042-1756305Uncontrolled bleeding is the leading cause of preventable death following injury. Trauma-induced coagulopathy can manifest as diverse phenotypes ranging from hypocoagulability to hypercoagulability, which can change quickly during the acute phase of trauma care. The major advances in understanding coagulation over the past 25 years have resulted from the cell-based concept, emphasizing the key role of platelets and their interaction with the damaged endothelium. Consequently, conventional plasma-based coagulation testing is not accurate in predicting bleeding and does not prov...
Source: Seminars in Thrombosis and Hemostasis - September 16, 2022 Category: Hematology Authors: Meizoso, Jonathan P. Barrett, Christopher D. Moore, Ernest E. Moore, Hunter B. Tags: Review Article Source Type: research

The Fibrinolytic System in Peripartum Depression
This article describes the fibrinolytic status in the healthy brain, in stress and depression, emphasizing the links between biological markers of depression and defective fibrinolysis. It also discusses the association between hypofibrinolysis and risk factors for perinatal depression, including polycystic ovary syndrome, early miscarriage, preeclampsia, stressful life events, sedentariness, eating habits, gestational and type 2 diabetes, and antithyroid peroxidase antibodies. In addition, it reviews the evidence that antidepressant medications and interventions as diverse as placebo, psychotherapy, massage, video game pl...
Source: Seminars in Thrombosis and Hemostasis - September 16, 2022 Category: Hematology Authors: Hoirisch-Clapauch, Silvia Tags: Review Article Source Type: research

Celebrating 50 Years of Seminars in Thrombosis and Hemostasis —Part I
Semin Thromb Hemost DOI: 10.1055/s-0042-1756301 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Favaloro, Emmanuel J. Tags: STH22 History I Preface Source Type: research

Risk Factors for Left Ventricular Thrombus Formation in Patients with Dilated Cardiomyopathy
Conclusion This study suggested that elevated D-dimer levels (>444 ng/mL DDU) and reduced EF were independently associated with increased risk of LVT formation. Severe MR could decrease the incidence of LVT. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Wu, Hao-Sheng Dong, Jian-Zeng Du, Xin Hu, Rong Jia, Chang-Qi Li, Xu Wu, Jia-Hui Ruan, Yan-Fei Yu, Rong-Hui Long, De-Yong Ning, Man Sang, Cai-Hua Jiang, Chen-Xi Bai, Rong Wen, Song-Nan Liu, Nian Li, Song-Nan Wang, Wei Guo, Xue-Yuan Zhao, Xin Zuo, Song Cui, Tags: Review Article Source Type: research

Viscoelastic Testing in the Management of Adult Patients on Mechanical Circulatory Support Devices with Focus on Extracorporeal Membrane Oxygenation
Semin Thromb Hemost DOI: 10.1055/s-0042-1756303Thromboembolic and hemorrhagic complications continue to remain frequent complications that significantly impact the morbidity and mortality of patients implanted with mechanical circulatory support devices (MCSDs). The severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2) has resulted in a number of COVID-19 patients being supported by MCSDs, specifically extracorporeal membrane oxygenation (ECMO), which in turn has created a crucial need for rapid assessment of hemostatic status in these patients to avoid bleeding and thrombotic complications. Currently, con...
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Volod, Oksana Wegner, Julie Tags: Review Article Source Type: research

Antiphospholipid Antibodies in Pregnancy: Maternal and Neonatal Implications
Semin Thromb Hemost DOI: 10.1055/s-0042-1756193Antiphospholipid antibodies (aPL Abs) have long been associated with the occurrence of certain specific pregnancy morbidities, affecting both mother and fetus. Antithrombotic-based prophylactic regimens are the standard of care. Their intensity is modulated by the thrombotic history and has greatly improved the prognosis related to spontaneous morbidity. Observational studies show that this treatment is still associated with the persistence of excess of late-pregnancy placental diseases, calling for new or complementary developments, yet to be validated. Rigorous prospective m...
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Gris, Jean-Christophe Guillotin, Florence Ch éa, Mathias Bourguignon, Chlo é Nouvellon, Éva Bouvier, Sylvie Tags: Review Article Source Type: research

The More Recent History of Hemophilia Treatment
Semin Thromb Hemost DOI: 10.1055/s-0042-1756188The availability first in the 1970s of plasma-derived and then in the 1990s of recombinant clotting factor concentrates represented a milestone in hemophilia care, enabling not only treatment of episodic bleeding events but also implementation of prophylactic regimens. The treatment of hemophilia has recently reached new landmarks. The traditional clotting factor replacement therapy for hemophilia has been substituted over the last 10 years by novel treatments such as bioengineered factor VIII and IX molecules with extended half-life and non-factor treatments including the bis...
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Franchini, Massimo Mannucci, Pier Mannuccio Tags: Review Article Source Type: research

Pulmonary Embolism and Chronic Obstructive Pulmonary Disease
Semin Thromb Hemost DOI: 10.1055/s-0042-1756190Chronic obstructive pulmonary disease (COPD) is a frequent and devastating chronic respiratory disease. COPD is ranked among the top five causes of death worldwide. Patients with COPD suffer from persistent dyspnea, with periods of acute worsening, called exacerbations. Such exacerbations may be severe. In fact, one-third of COPD patients will be hospitalized because of an exacerbation. Hospitalization due to respiratory failure has been identified as a powerful predisposing risk factor for venous thromboembolism (VTE) for many years. Therefore, COPD is recognized as a moderat...
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Bertoletti, Laurent Couturaud, Francis Sanchez, Olivier Jimenez, David Tags: Review Article Source Type: research

Intracranial Hemorrhages in Neonates: Incidence, Risk Factors and Treatment
Semin Thromb Hemost DOI: 10.1055/s-0042-1756195Hemostasis is a dynamic process that starts in utero. Neonates, especially those who are born preterm, are at high risk of bleeding. The coagulation system evolves with age, and the decreased levels of coagulation factors along with hypo-reactive platelets are counterbalanced with increased activity of von Willebrand factor, high hematocrit and mean corpuscular volume as well as low levels of coagulation inhibitors that promote hemostasis. Neonates with congenital bleeding disorders such as hemophilia are at even higher risk of bleeding complications. This review will focus up...
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Andersson, Nadine G. Kenet, Gili Tags: Review Article Source Type: research

Toward 50 years of Seminars in Thrombosis and Hemostasis
Semin Thromb Hemost DOI: 10.1055/s-0042-1756189 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 15, 2022 Category: Hematology Authors: Favaloro, Emmanuel J. Tags: Editorial Source Type: research

Disseminated Intravascular Coagulation: The Past, Present, and Future Considerations
Semin Thromb Hemost DOI: 10.1055/s-0042-1756300Disseminated intravascular coagulation (DIC) has been understood as a consumptive coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a progressive manner. The critical concept of DIC is systemic activation of coagulation with vascular endothelial damage. DIC is the dynamic coagulation/fibrinolysis disorder that can proceed from compensated to decompensated phases, and is not simply impaired hemostasis, a misunderstanding that continues to evoke confusion among clinicians. DIC is a critical step of disease progression that is important to monitor ov...
Source: Seminars in Thrombosis and Hemostasis - September 13, 2022 Category: Hematology Authors: Iba, Toshiaki Levi, Marcel Thachil, Jecko Levy, Jerrold H. Tags: Review Article Source Type: research

Viscoelastic Testing in the Clinical Management of Subarachnoid Hemorrhage and Intracerebral Hemorrhage
In conclusion, viscoelastic testing suggests hypercoagulation following SAH and ICH. Further investigation of the predictive value of increased clot firmness in SAH seems relevant. In ICH, the prediction of hematoma expansion and ICH as a complication to thrombolysis might be clinically relevant. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - September 13, 2022 Category: Hematology Authors: Hvas, Christine Lodberg Hvas, Anne-Mette Tags: Review Article Source Type: research