Orbital Development in Children with Retinoblastoma: An Imaging-Based Study
CONCLUSIONS: Orbital growth rate is slower in the orbits of children treated for Rb compared to healthy orbits. Enucleation negatively affects orbital growth.PMID:38329101 | DOI:10.1080/08820538.2024.2312968 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - February 8, 2024 Category: Opthalmology Authors: Shir Forer Guy J Ben Simon Gahl Greenberg Lital Smadar Amit Zabatani Mattan Arazi Ido Didi Fabian Vicktoria Vishnevskia-Dai Daphna Landau-Prat Source Type: research

Viral Keratitis, Surgical Intervention in Viral Keratitis, Challenges in Diagnosis and Treatment of Viral Keratitis, HSV, HZV
Semin Ophthalmol. 2024 Feb 1:1-13. doi: 10.1080/08820538.2024.2309533. Online ahead of print.ABSTRACTViral keratitis is a significant cause of ocular morbidity and visual impairment worldwide. In recent years, there has been a growing understanding of the pathogenesis, clinical manifestations, and diagnostic modalities for viral keratitis. The most common viral pathogens associated with this condition are adenovirus, herpes simplex (HSV), and varicella-zoster virus (VZV). However, emerging viruses such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), and Vaccinia virus can also cause keratitis. Non-surgical intervention...
Source: Seminars in Ophthalmology - February 2, 2024 Category: Opthalmology Authors: Anitha Venugopal Josephine Christy Vaidehi Raut Preethi P Veena Patwardhan Veeramma V Aditee Madkaikar Mangala P Ravindran Meenakshi Rangappa Ramakrishnan Source Type: research

Anatomical and Functional Results of Early or Late Switching from Anti-VEGF to Dexamethasone Implant in Case of Poor Anatomical Response in Na ïve Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion
CONCLUSIONS: A gain of 15 or more letters was demonstrated to be higher in patients who switched to DEX implant late after anti-VEGF treatment. If it is necessary to switch, the late switch may be more effective for more visual gain at the end of the first year.PMID:38282256 | DOI:10.1080/08820538.2024.2310662 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 29, 2024 Category: Opthalmology Authors: Z übeyir Yozgat Mehmed U ğur Işik Source Type: research

Intravitreal Brolucizumab for Chronic Central Serous Chorioretinopathy without Choroidal Neovascular Membrane - a Pilot Study
CONCLUSION: Intravitreal brolucizumab is effective in the rapid reduction of persistent macular fluid in chronic CSCR without CNVM. Long-term follow-up data are required to study recurrence and adverse effect profile.PMID:38270124 | DOI:10.1080/08820538.2024.2308808 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 25, 2024 Category: Opthalmology Authors: Srishti Raksheeth Ramamurthy Umesh Chandra Behera Ritesh Narula SriniVas R Sadda Raja Narayanan Source Type: research

Clinico-Microbiological Correlation in < em > Salmonella < /em > Endophthalmitis: Case Series and Review of Literature
CONCLUSIONS: Salmonella endophthalmitis, though rare, leads to poor visual outcomes despite early recognition and aggressive management and may be confused with other infections or non-infectious entities such as necrotizing retinoblastoma in babies, in the absence of clear systemic signs of the disease.PMID:38254268 | DOI:10.1080/08820538.2024.2308802 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 23, 2024 Category: Opthalmology Authors: Sanchita Mitra Bhagyashree Meshram Subhadra Jalali Soumyava Basu Source Type: research

Lacrimal History - Part III: Doyens of Dacryology Series - Addeo Toti and External Dacryocystorhinostomy
Semin Ophthalmol. 2024 Jan 23:1-2. doi: 10.1080/08820538.2024.2308957. Online ahead of print.NO ABSTRACTPMID:38258839 | DOI:10.1080/08820538.2024.2308957 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 23, 2024 Category: Opthalmology Authors: Sen Mrittika Mohammad Javed Ali Source Type: research

Readership Awareness Series - Paper 9: Retraction of a Publication
Semin Ophthalmol. 2024 Jan 18:1-2. doi: 10.1080/08820538.2024.2306434. Online ahead of print.NO ABSTRACTPMID:38238881 | DOI:10.1080/08820538.2024.2306434 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 18, 2024 Category: Opthalmology Authors: Mohammad Javed Ali Ali Djalilian Source Type: research

TGF- β1 Mediates the EndoMt in High Glucose-Treated Human Retinal Microvascular Endothelial Cells
Semin Ophthalmol. 2024 Jan 8:1-8. doi: 10.1080/08820538.2023.2300806. Online ahead of print.ABSTRACTThe purpose of our study was to investigate the role of TGF-β1 in the endothelial-to-mesenchymal transition (EndoMT) and fibrosis in high glucose (HG)-treated human retinal microvascular endothelial cells (HRMECs). HRMECs were cultured not only under normal glucose (NG) conditions with or without TGF-β1, but also under HG conditions with or without the TGF-β1 inhibitor SB431542. The expression of TGF-β1 was detected by real time-PCR and enzyme-linked immunosorbent assay. Morphological changes and migration of the HRMECs ...
Source: Seminars in Ophthalmology - January 9, 2024 Category: Opthalmology Authors: Jia Ying Peipei Wang Xiao Jin Li Luo Keshuang Lai Jun Li Source Type: research

Large Language Models in Ophthalmology: Potential and Pitfalls
Semin Ophthalmol. 2024 Jan 5:1-5. doi: 10.1080/08820538.2023.2300808. Online ahead of print.ABSTRACTLarge language models (LLMs) show great promise in assisting clinicians in general, and ophthalmology in particular, through knowledge synthesis, decision support, accelerating research, enhancing education, and improving patient interactions. Specifically, LLMs can rapidly summarize the latest literature to keep clinicians up-to-date. They can also analyze patient data to highlight crucial insights and recommend appropriate tests or referrals. LLMs can automate tedious research tasks like data cleaning and literature review...
Source: Seminars in Ophthalmology - January 5, 2024 Category: Opthalmology Authors: Antonio Yaghy Maria Yaghy Jerry A Shields Carol L Shields Source Type: research