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Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee
Semin Musculoskelet Radiol 2023; 27: 618-631 DOI: 10.1055/s-0043-1775741Chronic knee pain is a common condition. Causes of knee pain include trauma, inflammation, and degeneration, but in many patients the pathophysiology remains unknown. Recent developments in advanced magnetic resonance imaging (MRI) techniques and molecular imaging facilitate more in-depth research focused on the pathophysiology of chronic musculoskeletal pain and more specifically inflammation. The forthcoming new insights can help develop better targeted treatment, and some imaging techniques may even serve as imaging biomarkers for predicting and ass...
Source: Seminars in Musculoskeletal Radiology - November 7, 2023 Category: Radiology Authors: Mostert, Jacob M. Dur, Niels B.J. Li, Xiufeng Ellermann, Jutta M. Hemke, Robert Hales, Laurel Mazzoli, Valentina Kogan, Feliks Griffith, James F. Oei, Edwin H.G. van der Heijden, Rianne A. Tags: Review Article Source Type: research

A Practical Guide to Sigma-1 Receptor Positron Emission Tomography/Magnetic Resonance Imaging: A New Clinical Molecular Imaging Method to Identify Peripheral Pain Generators in Patients with Chronic Pain
Semin Musculoskelet Radiol 2023; 27: 601-617 DOI: 10.1055/s-0043-1775744Accurately identifying the peripheral pain generator in patients with chronic pain remains a major challenge for modern medicine. Millions of patients around the world suffer endlessly from difficult-to-manage debilitating pain because of very limited diagnostic tests and a paucity of pain therapies. To help these patients, we have developed a novel clinical molecular imaging approach, and, in its early stages, it has been shown to accurately identify the exact site of pain generation using an imaging biomarker for the sigma-1 receptor and positron emi...
Source: Seminars in Musculoskeletal Radiology - November 7, 2023 Category: Radiology Authors: Shen, Bin Yoon, Daehyun Castillo, Jessa Biswal, Sandip Tags: Review Article Source Type: research

Molecular and Functional Imaging of Musculoskeletal Pain, Inflammation, and Arthritis
Semin Musculoskelet Radiol 2023; 27: 599-600 DOI: 10.1055/s-0043-1776052 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Musculoskeletal Radiology)
Source: Seminars in Musculoskeletal Radiology - November 7, 2023 Category: Radiology Authors: Biswal, Sandip Tags: Preface Source Type: research

Erratum: Current Role of Conventional Radiography of Sacroiliac Joints in Adults and Juveniles with Suspected Axial Spondyloarthritis: Opinion from the ESSR Arthritis and Pediatric Subcommittees
Semin Musculoskelet Radiol 2023; 27: e1-e1 DOI: 10.1055/s-0043-1776395 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Musculoskeletal Radiology)
Source: Seminars in Musculoskeletal Radiology - October 27, 2023 Category: Radiology Authors: Sudo ł-Szopińska, Iwona Herregods, Nele Zejden, Anna Jans, Lennart Giraudo, Chiara Boesen, Mikael Becce, Fabio Bazzocchi, Alberto Simoni, Paolo Aparisi G ómez, Maria Pilar Jaremko, Jacob Maas, Mario Teh, James Hermann, Kay-Geert Menegotto, Flavia Isaac Tags: ERRATA Source Type: research

History Page: Leaders in MSK Radiology Brian Joseph Cremin (1929 –2012)
Semin Musculoskelet Radiol 2023; 27: 596-598 DOI: 10.1055/s-0043-1763262This history page in the series “Leaders in MSK Radiology” is dedicated to the achievements of the British radiologist Brian Cremin, one of the pioneers of imaging of skeletal dysplasias. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Musculoskeletal Radiology)
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Beighton, Peter Tags: History Page Source Type: research

Current Role of Conventional Radiography of Sacroiliac Joints in Adults and Juveniles with Suspected Axial Spondyloarthritis: Opinion from the ESSR Arthritis and Pediatric Subcommittees
Semin Musculoskelet Radiol 2023; 27: 588-595 DOI: 10.1055/s-0043-1772169This opinion article by the European Society of Musculoskeletal Radiology Arthritis and Pediatric Subcommittees discusses the current use of conventional radiography (CR) of the sacroiliac joints in adults and juveniles with suspected axial spondyloarthritis (axSpA). The strengths and limitations of CR compared with magnetic resonance imaging (MRI) and computed tomography (CT) are presented.Based on the current literature and expert opinions, the subcommittees recognize the superior sensitivity of MRI to detect early sacroiliitis. In adults, supplement...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Sudo ł-Szopińska, Iwona Herregods, Nele Zejden, Anna Jans, Lennart Giraudo, Chiara Boesen, Mikael Becce, Fabio Bazzocchi, Alberto Simoni, Paolo Aparisi, Pilar Jaremko, Jacob Maas, Mario Teh, James Hermann, Kay-Geert Menegotto, Flavia Isaac, Amanda Reijn Tags: Review Article Source Type: research

What the Musculoskeletal Radiologist Needs to Know About the Vascular Anatomy of the Spine and Spinal Cord
This article describes the vascular anatomy of the spine and spinal cord, highlighting key structures and anatomical variations relevant to musculoskeletal radiologists. It covers the arterial and venous drainage systems, along with examples of vascular conditions affecting the spine. Understanding the vascular anatomy of the spine and spinal cord is crucial for accurate interpretation of imaging studies and safe spinal interventional procedures. Imaging techniques for evaluating vascular pathology of the spine are discussed and compared. Understanding vascular anatomy and the most common vascular disorders will lead to an...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Duarte Armindo, Rui Vilela, Pedro Tags: Review Article Source Type: research

Update on Pediatric Spine Imaging
Semin Musculoskelet Radiol 2023; 27: 566-579 DOI: 10.1055/s-0043-1771333The spine is often difficult to evaluate clinically in children, increasing the importance of diagnostic imaging to detect a wide variety of spinal disorders ranging from congenital abnormalities to severe infections. Clinical history and physical examination can help determine whether imaging is needed and which imaging technique would be best. The most common cause for back pain, even in children, is muscular strain/spasm that does not require any imaging. However, red flags such as pain at age < 5 years, constant pain, night pain, radicular p...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Schatteman, Stijn Jaremko, Jacob Jans, Lennart Herregods, Nele Tags: Review Article Source Type: research

Results of an International Survey on Spinal Imaging by the ASNR/ASSR/ESNR/ESSR “Nomenclature 3.0” Working Group
Semin Musculoskelet Radiol 2023; 27: 561-565 DOI: 10.1055/s-0043-1768247Our goal was to determine if “Nomenclature 2.0,” the classification of lumbar disk pathology consensus, should be updated. We conducted a social media and e-mail-based survey on preferences regarding the use of classification on magnetic resonance spine reporting. Members of the European Society of Neuroradiology, European Society of Musculoskeletal Radiology, American Society of Neuroradiology, and American Society of Spine Radiology received a 15-question online survey between February and March 2022. A total of 600 responses were received from 6...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: D'Anna, Gennaro Shah, Lubdha Kranz, Peter G. Hirsch, Joshua A. Khan, M. Johnson, Michele Feydy, Antoine Nathan, J. Manfre, L. Nguyen, Dan T. Sze, Gordan Goethem, Johan Van Vanhoenacker, Filip M. Tags: Review Article Source Type: research

Imaging the Posterior Elements of the Spine
Semin Musculoskelet Radiol 2023; 27: 553-560 DOI: 10.1055/s-0043-1770996The posterior elements of the spine consist of the pedicles, laminae, facets (articular processes), transverse processes, and the spinous process. They are essential for spinal stability, protecting the spinal cord and nerve roots, and enabling movement of the spine. Pathologies affecting the posterior elements can cause significant pain and disability. Imaging techniques, such as conventional radiography, computed tomography, and magnetic resonance imaging, are crucial for the diagnosis and evaluation of pathology, enabling accurate localization, char...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Eede, Nick Van den Friedrich, Klaus M. Hauwe, Luc van den Tags: Review Article Source Type: research

Crystal Diseases of the Spine
This article presents the typical and more unusual imaging features encountered in these disorders. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Musculoskeletal Radiology)
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Cotten, Anne Henry, Simon Scarciolla, Laura Abou Diwan, Ralph Demondion, Xavier Badr, Sammy Tags: Review Article Source Type: research

Scoliosis
Semin Musculoskelet Radiol 2023; 27: 529-544 DOI: 10.1055/s-0043-1772168Scoliosis is a three-dimensional spinal deformity that can occur at any age. It may be idiopathic or secondary in children, idiopathic and degenerative in adults. Management of patients with scoliosis is multidisciplinary, involving rheumatologists, radiologists, orthopaedic surgeons, and prosthetists. Imaging plays a central role in diagnosis, including the search for secondary causes, follow-up, and preoperative work-up if surgery is required. Evaluating scoliosis involves obtaining frontal and lateral full-spine radiographs in the standing position,...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Lacroix, Maxime Khalif é, Marc Ferrero, Emmanuelle Cl ément, Olivier Nguyen, Christelle Feydy, Antoine Tags: Review Article Source Type: research

Scheuermann's Disease
Semin Musculoskelet Radiol 2023; 27: 522-528 DOI: 10.1055/s-0043-1771334Scheuermann's disease is a rigid progressive kyphosis occurring in late childhood to adolescence. It is the most common cause of sagittal imbalance and angular progressive kyphosis in adolescents associated with back pain. The exact etiology of the disease is unclear, but it is characterized by defective growth of the end plate that may result from excessive mechanical stress on a weakened end plate during spinal growth. Several other theories have been proposed, and it is thought to be a multifactorial disease occurring as a result of the interplay of...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Kaur, Simranjeet Lalam, Radhesh Tags: Review Article Source Type: research

Imaging in Whiplash-Associated Disorders
Semin Musculoskelet Radiol 2023; 27: 512-521 DOI: 10.1055/s-0043-1772170“Whiplash,” a term describing the severe acceleration and deceleration forces applied to the head, craniocervical junction (CCJ), and cervical spine during trauma, is one of the most frequent mechanisms of injury to the CCJ. The CCJ is a complex region at the transition of the cranium and the cervical spine, essential for maintaining craniocervical stability. In whiplash injuries, the CCJ may be compromised due to underlying ligamentous or, less frequently, osseous, intravertebral disk and/or muscular lesions. Imaging is crucial in detecting acute ...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Schollaert, Joris Van Goethem, Johan W.M. Tags: Review Article Source Type: research

Imaging of the Craniocervical Junction: A Pictorial Review
Semin Musculoskelet Radiol 2023; 27: 499-511 DOI: 10.1055/s-0043-1772190The craniocervical junction (CCJ) is a complex anatomical structure comprising the occiput, the atlas, and the axis. The CCJ plays an important role in maintaining stability, providing protection, and supporting neurovascular structures. The CCJ can be affected by a wide range of congenital variants and traumatic, degenerative, inflammatory, and tumoral pathologies. This pictorial review the normal anatomy of the CCJ and presents the most common anatomical variants and pathologic conditions affecting the CCJ. [...] Thieme Medical Publishers, Inc. 333 S...
Source: Seminars in Musculoskeletal Radiology - October 10, 2023 Category: Radiology Authors: Mertens, Kris Vanhoenacker, Filip M. Tags: Review Article Source Type: research