Seminars in Fetal and Neonatal Medicine Seminars in Fetal and Neonatal Medicine RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Expanding Neonatal ECMO Criteria: When is the Premature Neonate too Premature
Extracorporeal membrane oxygenation (ECMO) is a universally accepted and life-saving therapy for neonates with respiratory or cardiac failure that is refractory to maximal medical management. Early studies found unacceptable risks of mortality and morbidities such as intracranial hemorrhage among premature and low birthweight neonates, leading to widely accepted ECMO inclusion criteria of gestational age ≥34 weeks and birthweight>2 kilograms. Although contemporary data is lacking, the most recent literature demonstrates increased survival and decreased rates of intracranial hemorrhage in premature neonates who are suppor...
Source: Seminars in Fetal and Neonatal Medicine - November 17, 2022 Category: Perinatology & Neonatology Authors: K. Taylor Wild, Carmen Mesas Burgos, Natalie E. Rintoul Source Type: research

Prenatal management of congenital diaphragmatic hernia
Recently, two randomized controlled, prospective trials, the Tracheal Occlusion to Accelerate Lung Growth (TOTAL) trials, reported the outcomes on fetal endoluminal tracheal occlusion (FETO) for isolated left congenital diaphragmatic hernia (CDH). FETO significantly improved outcomes for severe hypoplasia. The effect in moderate cases, where the balloon was inserted later in pregnancy, did not reach significance. In a pooled analysis investigating the effect of the heterogeneity of the treatment effect by the time point of occlusion and severity, the difference may be explained by a difference in the duration of occlusion....
Source: Seminars in Fetal and Neonatal Medicine - November 17, 2022 Category: Perinatology & Neonatology Authors: Enrico Danzer, Natalie E. Rintoul, Krisa P. van Meurs, Jan Deprest Source Type: research

Management of the CDH patient on ECLS
Congenital diaphragmatic hernia (CDH) is the most common indication for respiratory extracorporeal life support (ECLS) in neonates. The survival rate of CDH neonates treated with ECLS is 50%, and this figure has remained relatively stable over the last few decades. This is likely because the current population of CDH neonates who require ECLS have a higher risk profile.1 The management of neonates with CDH has evolved over time to emphasize postnatal stabilization, gentle ventilation, and multi-modal treatment of pulmonary hypertension. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - November 17, 2022 Category: Perinatology & Neonatology Authors: Alice Martino, Gianluca Lista, Yigit S. Guner Source Type: research

Editorial
As with all medical advancements, there are key individuals and multidisciplinary research and medical teams involved in directing these new therapies forward. The development of therapeutic modalities for infants in respiratory failure is an excellent example of this team approach. In this issue of Seminars in Fetal& Neonatal Medicine we have assembled nine chapters written by such collaborators and experts in treatment of these complex infants, with a focus on the use of neonatal extracorporeal life support (ECLS) in this population. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - November 16, 2022 Category: Perinatology & Neonatology Authors: Billie Lou Short Tags: Editorial Source Type: research

Changing populations being treated with ECMO in the neonatal period – who are the others?
Extracorporeal life support via extracorporeal membrane oxygenation (ECMO) has served the sickest of neonates for almost 50 years. Naturally, the characteristics of neonates receiving ECMO have changed. Advances in care have averted the need for ECMO for some, while complex cases with uncertain outcomes, previously not eligible for ECMO, are now considered. Characterizing the disease states and outcomes for neonates on ECMO is challenging as many infants do not fall into classic categories, i.e. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - November 16, 2022 Category: Perinatology & Neonatology Authors: Allison T. Rose, Sarah Keene Source Type: research

Coagulation and Hemolysis Complications in Neonatal ECLS: Role of Devices
Neonatal extracorporeal life support (ECLS) has enjoyed a long history of successful patient support for both cardiac and respiratory failure. The small size of this patient population has provided many technical challenges from cannulation to pumps and oxygenators. This is further complicated by the relatively meager commercial options for equipment owing to the relatively low utilization of neonatal ECLS compared to adults, which has exploded following the H1N1 epidemic and the availability of the polymethylpentene oxygenator. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - November 16, 2022 Category: Perinatology & Neonatology Authors: Timothy M. Maul, Guillermo Herrera Source Type: research

Milestones for Clinical Translation of the Artificial Placenta
Despite significant advances in the treatment of prematurity, premature birth results in significant mortality and morbidity. In particular, extremely low gestational age newborns (ELGANs) defined as (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - November 16, 2022 Category: Perinatology & Neonatology Authors: Brianna L. Spencer, George B. Mychaliska Source Type: research

Data analytics in a clinical setting: Applications to understanding breathing patterns and their relevance to neonatal disease
In this review, we focus on the use of contemporary linear and non-linear data analytics as well as machine learning/artificial intelligence algorithms to inform treatment of pediatric patients. We specifically focus on methods used to quantify changes in breathing that can lead to increased risk for apnea of prematurity, retinopathy of prematurity (ROP), necrotizing enterocolitis (NEC) and provide a list of potentially useful algorithms that comprise a suite of software tools to enhance prediction of outcome. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 31, 2022 Category: Perinatology & Neonatology Authors: Christopher G. Wilson, A. Erika Altamirano, Tyler Hillman, John B. Tan Source Type: research

Telemedicine Across the Continuum of Neonatal-Perinatal Care
Acknowledgements (Individuals listed alphabetically): This work is supported through a collaboration between the Childrens Hospital Neonatal Consortium (CHNC), a 501(c)(3)(b)), Digital Health Working Group, and Supporting Pediatric Research in Outcomes and Utilization of Telehealth (SPROUT); funded in part by National Institutes of Health (NIH) National Center for Advancing Translational Science (NCATS) Grant #U01TR002626. Kathy Kyler for editing support for this manuscript. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 28, 2022 Category: Perinatology & Neonatology Authors: John Chuo, Abhishek Makkar, Kerri Machut, Jeanne Zenge, Jawahar Jagarapu, Abeer Azzuqa, Rashmin C. Savani Source Type: research

Overview
This issue of Seminars in Fetal& Neonatal Medicine reviews some of the current advances in neonatal and fetal medicine that span new technologic changes that are emerging as well as concepts and innovation occurring in the field of neonatal informatics. Both these areas touch on the introduction of novel approaches that are changing the way we practice neonatology and thereby present additional challenges in adopting these potentially beneficial practices. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 28, 2022 Category: Perinatology & Neonatology Authors: Jae H. Kim Tags: Editorial Source Type: research

Learning with Digital Recording and Video Review of Delivery Room Resuscitation
Digital recording and video review of delivery room resuscitations is a proven useful tool to evaluate neonatal resuscitation program (NRP) technical and non-technical skills. It is also valuable for research, quality improvement, and individual and group learning. Digital recording and video review programs are growing in number, and planning and implementation of digital recording requires careful thought. Consideration of technology requirements, policy implementation, and stakeholder involvement is essential to implement a successful digital recording and video review program. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 18, 2022 Category: Perinatology & Neonatology Authors: Morgan E. Hill, Sofia R. Aliaga, Elizabeth E. Foglia Source Type: research

Neonatal POCUS: Embracing our modern day “stethoscope”
The dramatic technologic advancements seen in ultrasound have accelerated the growth of point-of-care ultrasound (POCUS) in medicine. Neonatology has lagged behind other pediatric and adult specialties in incorporating POCUS into clinical practice despite there being numerous applications in cardiac and non-cardiac arenas. Widely available training programs are aiding in improving this situation but significantly more structure and orchestration for neonatal POCUS dissemination will be needed to fully actualize the potential for POCUS to augment its widespread clinical application. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 13, 2022 Category: Perinatology & Neonatology Authors: Jennifer Shepherd, Shanmukha Mukthapuram, Jae H. Kim Source Type: research

Pivotal Challenges in Artificial Intelligence and Machine Learning Applications for Neonatal Care
Clinical decision support systems (CDSS) that are developed based on artificial intelligence and machine learning (AI/ML) approaches carry transformative potentials in improving the way neonatal care is practiced. From the use of the data available from electronic health records to physiological sensors and imaging modalities, CDSS can be used to predict clinical outcomes (such as mortality rate, hospital length of state, or surgical outcome) or early warning signs of diseases in neonates. However, only a limited number of clinical decision support systems for neonatal care are currently deployed in healthcare facilities o...
Source: Seminars in Fetal and Neonatal Medicine - October 12, 2022 Category: Perinatology & Neonatology Authors: Hayoung Jeong, Rishikesan Kamaleswaran Source Type: research

Usability of Human-Computer Interaction in Neonatal Care
While a goal for Electronic Health Record (EHR) technologies was to improve quality, efficiency, and safety, the usability of EHRs has remained poor. The relation to patient harm and user satisfaction cannot be ignored. Optimization of EHR usability is imperative to improving the outcomes for critically ill patients, especially neonates who are at the extremes of physiologic variability. Further development and integration of metadata with predictive modeling and clinical protocols can support provider decision making, increase efficiency and safety, and reduce clinician burnout. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 12, 2022 Category: Perinatology & Neonatology Authors: Kevin R. Dufendach, Adriana Navarro-Sainz, Kristen LW. Webster Source Type: research

Editorial Board
(Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - October 1, 2022 Category: Perinatology & Neonatology Source Type: research