Comparison of patients diagnosed with “complex pain” and “somatoform pain”
Conclusion These comparisons lend support to the viewpoint of non-segregation of somatoform and complex pain. Implications Pain treatment might be better-managed in common multidisciplinary centers with specialists in both pain treatment and psychiatric aid. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 27, 2017 Category: Anesthesiology Source Type: research
Chronic disruptive pain in emerging adults with and without chronic health conditions and the moderating role of psychiatric disorders: Evidence from a population-based cross-sectional survey in Canada
Conclusions There is a robust association between CHCs and chronic disruptive pain. The moderating effects suggest that alcohol or drug disorders are especially harmful for emerging adults without CHCs and contribute to higher levels of chronic disruptive pain; however, among those with CHCs, alcohol and illicit drugs may be used as a numbing agent to blunt chronic disruptive pain. Implications Findings from this study have implications for the integration and coordination of services to design strategies aimed at managing chronic disruptive pain and preventing pain-related disabilities later in life. Within the health sy...
Source: Scandinavian Journal of Pain - July 27, 2017 Category: Anesthesiology Source Type: research
Behavioral inhibition, maladaptive pain cognitions, and function in patients with chronic pain
Conclusions If replicated in additional studies, the findings would indicate that chronic pain treatments which target both reductions in maladaptive cognitions (to decrease the direct negative effects of these on depressive symptoms) and the individual's tendency to respond to pain with worry (as a way to buffer the potential effects of maladaptive cognitions on depressive symptoms) might be more effective than treatments that targeted only one of these factors. Implications Additional research is needed to further evaluate the direct and moderating effects of pain-related behavioral inhibition on function, as well as th...
Source: Scandinavian Journal of Pain - July 27, 2017 Category: Anesthesiology Source Type: research
Prevalence and characteristics of chronic pain: Experience of Niger
Conclusion Our study provides demographic, clinical and etiological data of chronic pain in patients from Niger, and shows that chronic pain is a common reason for consultation in Niger concerning 1 in 5 patients with a high prevalence among men and patients aged over 40 years. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 26, 2017 Category: Anesthesiology Source Type: research
Acid-induced experimental muscle pain and hyperalgesia with single and repeated infusion in human forearm
Conclusions The intensity of acid-induced muscle pain is pH-dependent. All three solutions induced pressure hyperalgesia at the infusion site. Repeated infusions did not induce increased pain or prolonged hyperalgesia as compared with a single injection. Human intramuscular acidic saline infusion could not produce chronic pain model. Implications The acid-induced pain model may reflect the early stage responses to tissue injury of clinical conditions. Repeated intramuscular acidic saline injection model of prolonged hyperalgesia in rodents could not be translated into a human for modelling chronic musculoskeletal pain. (S...
Source: Scandinavian Journal of Pain - July 25, 2017 Category: Anesthesiology Source Type: research
Clinical outcome following anterior arthrodesis in patients with presumed sacroiliac joint pain
Conclusions It is apparent that in some patients the SI joints may cause long-term pain that can be treated by arthrodesis. We speculate that continued pain despite a healed arthrodesis may be due to persistent pain from adjacent ligaments. The next step should be a prospective randomized study comparing posterior fusion and ligament resection with non-surgical treatment. Implications Anterior arthrodesis can apparently relieve pain in some patients with presumed SI joint pain. The problem is how to identify these patients within the low back pain group. Graphical abstract (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 25, 2017 Category: Anesthesiology Source Type: research
The Functional Barometer – An analysis of a self-assessment questionnaire with ICF-coding regarding functional/activity limitations and quality of life due to pain – Differences in age gender and origin of pain
Conclusion The significant differences regarding functioning, activity and quality-of-life between women and men as age and origin of pain must be taken into account when tailoring individual treatment and rehabilitation programmes. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 25, 2017 Category: Anesthesiology Source Type: research
The wit and wisdom of Wilbert (Bill) Fordyce (1923 – 2009)
Publication date: July 2017 Source:Scandinavian Journal of Pain, Volume 16 Author(s): Stephen Butler (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 15, 2017 Category: Anesthesiology Source Type: research
Prospective, double blind, randomized, controlled trial comparing vapocoolant spray versus placebo spray in adults undergoing intravenous cannulation
Conclusions and Implications Vapocoolant spray significantly decreased peripheral intravenous cannulation pain in adults versus placebo spray and was well tolerated with minor adverse effects that resolved quickly. There were no significant differences in vital signs and no visible skin changes documented by photographs taken within 5–10min postspray/PIV. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 10, 2017 Category: Anesthesiology Source Type: research
Perceived sleep deficit is a strong predictor of RLS in multisite pain – A population based study in middle aged females
Conclusions Perceived sleep deficit and sleep fragmentation are the strongest sleep related predictors of RLS in multisite pain. Potential implication of our results are that clinical management programmes of RLS in subjects with multisite pain need to consider both sleep quality and sleep quantity for individually tailored treatment regimes. Study impact RLS, pain, and sleep disorders are highly interrelated. Our study strongly suggests that clinical management of RLS in patients with multisite pain needs to consider sleep quality as an independent risk factor. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - July 4, 2017 Category: Anesthesiology Source Type: research
Couples coping with chronic pain: How do intercouple interactions relate to pain coping?
Conclusions Each of the four approaches find some support in the research literature, yet none of them can explain the full range of couple interactions. We argue that the different approaches are complementary and that several of the approaches can be integrated in a dyadic understanding of pain coping. Implications All the models indicate that couple interactions can affect pain coping and that this should be taken into account when developing treatment programmes for chronic pain patients. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - June 28, 2017 Category: Anesthesiology Source Type: research
Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist
Publication date: July 2017 Source:Scandinavian Journal of Pain, Volume 16 Author(s): Harald Breivik, Audun Stubhaug (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - June 27, 2017 Category: Anesthesiology Source Type: research
Randomized, double-blind, placebo-controlled, dose-escalation study: Investigation of the safety, pharmacokinetics, and antihyperalgesic activity of l-4-chlorokynurenine in healthy volunteers
Conclusions Although, AV-101 did not reach statistical significance in reducing pain, there were consistent reductions, for allodynia pain and mechanical and heat hyperalgesia. Given the excellent safety profile and PK characteristics demonstrated by this study, future clinical trials of AV-101 in neuropathic pain are justified. Implications This article presents the safety and PK of AV-101, a novel oral prodrug producing a potent and selective GlyB site antagonist of the NMDA receptor. These data indicate that AV-101 has excellent safety and PK characteristics providing support for advancing AV-101 into Phase 2 studies i...
Source: Scandinavian Journal of Pain - June 16, 2017 Category: Anesthesiology Source Type: research
Spinal analgesia for severe cancer pain: A retrospective analysis of 60 patients
Conclusions and implications Spinal administration of opioids is a safe and effective method of pain management in patients with severe cancer pain and can greatly reduce the need of systemic opioids. We are implementing closer collaboration with oncologists to provide spinal analgesia to more patients and earlier to reduce suffering. Catheter dislocation led to discontinuation of spinal analgesia in 17% of the patients and we are evaluating new ways to prevent catheter dislocation. The initial median spinal opioid dose was too low in both groups, and we are now using higher initial doses. A common adverse effect was numbn...
Source: Scandinavian Journal of Pain - June 15, 2017 Category: Anesthesiology Source Type: research
NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
Publication date: July 2017 Source:Scandinavian Journal of Pain, Volume 16 Author(s): Harald Breivik (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - June 15, 2017 Category: Anesthesiology Source Type: research
