Importance for patients of feeling accepted and understood by physicians before and after multimodal pain rehabilitation
Publication date: Available online 12 September 2017 Source:Scandinavian Journal of Pain Author(s): Maddy Greville-Harris (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - September 12, 2017 Category: Anesthesiology Source Type: research

Context sensitive regulation of pain and emotion: Development and initial validation of a scale for context insensitive avoidance
Conclusions We found support for the final version of our instrument, capturing one prominent aspect of context insensitivity. Avoidance of expression was related to higher ratings of pain, disability, catastrophizing and suppression as well as to lower levels of self-compassion. We encourage further studies to explore the impact of context insensitive avoidance for regulating pain and associated negative emotions. Yet, more research is needed that goes beyond self-report and includes other aspects of context. It is urgent to develop systematic ways for assessing context insensitivity, as it will enhance our understanding ...
Source: Scandinavian Journal of Pain - September 12, 2017 Category: Anesthesiology Source Type: research

Is the search for a “pain personality” of added value to the Fear-Avoidance-Model (FAM) of chronic pain?
Publication date: Available online 12 September 2017 Source:Scandinavian Journal of Pain Author(s): Katja Boersma (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - September 12, 2017 Category: Anesthesiology Source Type: research

Chronic low back pain and the transdiagnostic process: How do cognitive and emotional dysregulations contribute to the intensity of risk factors and pain?
Conclusions Our results indicate an important role of some dimensions of difficulties in emotional regulation, somatosensory amplification and rumination in the increase in negative affects and dysfunctional beliefs, and in the links between those psychological risk factors and pain/disability. Implications This study identifies some cognitive and emotional dysregulations substantially involved in work-related chronic pain. This contribute to put in place psychotherapeutic protocols to tackle these deficits and dysregulations in a relevant way. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - September 11, 2017 Category: Anesthesiology Source Type: research

Physical Diagnosis of Pain, 3rd ed., S. Waldman (2016)
Publication date: Available online 11 September 2017 Source:Scandinavian Journal of Pain Author(s): Harald Breivik (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - September 11, 2017 Category: Anesthesiology Source Type: research

What constitutes back pain flare? A cross sectional survey of individuals with low back pain
Conclusions The key finding was that many people with LBP do not consider their condition to be flared simply on the basis of a pain increase. In general, other features were required to also change. Results highlighted that a narrow focus on pain is unlikely to differentiate minor pain events from a flare. These findings are important as they contrast with most commonly used definitions of a flare that focus predominantly on pain increase. Implications Our findings have implications for understanding the trajectory of LBP over time. Understandings derived from perspectives of individuals with LBP highlight that defining ...
Source: Scandinavian Journal of Pain - September 1, 2017 Category: Anesthesiology Source Type: research

Quantitative sensory tests (QST) are promising tests for clinical relevance of anti-nociceptive effects of new analgesic treatments
Publication date: October 2017 Source:Scandinavian Journal of Pain, Volume 17 Author(s): Satu K. Jääskeläinen (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - September 1, 2017 Category: Anesthesiology Source Type: research

Targeting cytokines for treatment of neuropathic pain
Publication date: Available online 24 August 2017 Source:Scandinavian Journal of Pain Author(s): Alice L. Hung, Michael Lim, Tina L. Doshi Background Neuropathic pain is a challenging condition often refractory to existing therapies. An increasing number of studies have indicated that the immune system plays a crucial role in the mediation of neuropathic pain. Exploration of the various functions of individual cytokines in neuropathic pain will provide greater insight into the mechanisms of neuropathic pain and suggest potential opportunities to expand the repertoire of treatment options. Methods A literature review ...
Source: Scandinavian Journal of Pain - August 24, 2017 Category: Anesthesiology Source Type: research

A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis
Conclusion Overall, mavatrep was associated with a significant reduction in pain, stiffness, and physical function when compared with placebo in patients with knee osteoarthritis. Mavatrep's safety profile was consistent with its mechanism of action as a TRPV1 antagonist. Implications Further studies are required to evaluate whether lower multiple doses of mavatrep can produce analgesic efficacy while minimizing adverse events, as well as the potential for improved patient counselling techniques to reduce the minor thermal burns related to decreased heat perception. Trial Registration: 2009-010961-21 (EudraCT Number). (So...
Source: Scandinavian Journal of Pain - August 24, 2017 Category: Anesthesiology Source Type: research

Behavioural inhibition in the context of pain: Measurement and conceptual issues
Publication date: October 2017 Source:Scandinavian Journal of Pain, Volume 17 Author(s): Rena Gatzounis, Johan W.S. Vlaeyen (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - August 17, 2017 Category: Anesthesiology Source Type: research

Effects of validating communication on recall during a pain-task in healthy participants
Conclusion These novel results suggest that validating communication can counteract interference due to pain catastrophizing on recall, at least in a controlled experimental setting. Implications Good communication by health professionals is of utmost importance for adherence to pain management. The current results expand our knowledge on the effects of pain communication by establishing and explaining a clear link between empathic communication and recall, highlighting the role of pain catastrophizing. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - August 12, 2017 Category: Anesthesiology Source Type: research

Spatial summation of pain and its meaning to patients
Publication date: October 2017 Source:Scandinavian Journal of Pain, Volume 17 Author(s): Michele Curatolo (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - August 12, 2017 Category: Anesthesiology Source Type: research

The use of rapid onset fentanyl in children and young people for breakthrough cancer pain
Conclusions Fentanyl lozenges seem to be safe and well tolerated in children as young as five years old, weighing as little as 13kg. Results suggest that children should always be started on the lowest available dose of chosen preparation and that this dose should be titrated according to response. This study demonstrates that there is no correlation between background opioid dose and effective dose of rapid onset fentanyl in children. This mirrors findings of similar studies in adults. There was a strong correlation between effective dose of fentanyl lozenge and weight. This may be in part due to clinicians being more inc...
Source: Scandinavian Journal of Pain - August 11, 2017 Category: Anesthesiology Source Type: research

Quantitative sensory tests fairly reflect immediate effects of oxycodone in chronic low-back pain
Conclusions The results suggest that anti-nociceptive effects assessed by QST fairly reflect clinical efficacy of oxycodone on low-back pain. Pressure pain detection threshold, heat pain detection threshold and single-stimulus electrical pain threshold may be more suitable to sort out potential non-responders rather than identifying potential responders to opioid medication. Future pre-clinical human research may consider these results when investigating the analgesic effect of opioid agonists by means of QST. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - August 10, 2017 Category: Anesthesiology Source Type: research

Comparison of spatial summation properties at different body sites
Conclusion Data from this investigation refutes the thesis that spatial summation of pain may be a contributing factor for the reported difference in chronicity rates between spinal and peripheral sites. It remains, however, a potentially important mechanism by which noxious inputs from multi-level pathology might integrate and contribute to pain. Implications While data from this project suggest that there are no regional differences in the properties of spatial summation of noxious stimuli, regional differences in other characteristics of the nociceptive system may yet provide insight into why some spinal pain is so hig...
Source: Scandinavian Journal of Pain - August 10, 2017 Category: Anesthesiology Source Type: research