Quantitative imaging of lipid droplets in single cells
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01525B, MinireviewAnushka Gupta, Gabriel Dorlhiac, Aaron M Streets The combination of next generation sequencing (NGS) and automated liquid handling platforms has led to a revolution in single-cell genomic studies. However, many molecules that are critical to understanding the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 18, 2018 Category: Chemistry Authors: Anushka Gupta Source Type: research

Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01509K, PaperMARTHA VARDAKI, Chad Garry Atkins, H. Georg Schulze, Dana V. Devine, Katherine Serrano, Michael W Blades, Robin F. B. Turner The standard practice in blood banks worldwide involves storage of red blood cells (RBCs) in plastic bags until they are needed for transfusion. During storage, the cells gradually degrade in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 18, 2018 Category: Chemistry Authors: MARTHA VARDAKI Source Type: research

Integrated microfluidic device for the separation, decomposition and detection of low molecular weight S nitrosothiols
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN00757H, PaperGerson Francisco Duarte Junior, Abdulghani Ismail, Sophie Griveau, Fanny D'Orly é, Jose Alberto Fracassi da Silva, Wendell Karlos Tomazelli Coltro, Fethi Bedioui, Anne Varenne S-nitrosothiols (RSNOs) are very important biomolecules that play crucial roles in many physiological and physiopathological processes. They act as NO-donor and are candidates for future medicines. Their identification and quantitation... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 18, 2018 Category: Chemistry Authors: Gerson Francisco Duarte Junior Source Type: research

Exploring the potential of electroless and electroplated noble metal –semiconductor hybrids within bio- and environmental sensing
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01632A, Critical ReviewD. Semenova, K. V. Gernaey, Y. E. Silina This manuscript provides an elaborate review on galvanic noble metal nanoparticles deposited onto semiconductor surfaces, from the preparation stage towards their application in biosensors and gas sensing. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: D. Semenova Source Type: research

Fourier Transform Infrared spectra of cells on glass coverslips. A further step in spectral pathology.
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01634H, PaperAbigail V Rutter, James Crees, Helen Wright, Daniel Gey van Pittius, Ibraheem Yousef, Josep Sul é-Suso Over the last few years, great effort has been placed on developing Fourier Transform Infrared (FTIR) microspectroscopy as a tool to help in the histopathological diagnosis of cancer. The ever... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: Abigail V Rutter Source Type: research

Microfluidic studies of bacterial biofilms and emerging analytical approaches
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01526K, Critical ReviewMohammad Pousti, Mir Pouyan Zarabadi, Mehran Abbaszadeh Amirdehi, Fran çois Paquet-Mercier, Jesse Greener Bacterial biofilms are among the oldest and most prevalent multicellular life forms on Earth and are increasingly relevant in research areas related to industrial fouling, medicine and biotechnology. The main... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: Mohammad Pousti Source Type: research

Poly(amidoamine)-coated magnetic particles for enhanced detection of Schistosoma circulating anodic antigen in endemic urine samples
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Christine F. Markwalter, Paul L. A. M. Corstjens, Claire M. Mammoser, Garrett Camps, Govert J. van Dam, David W. Wright Charge-based biomarker concentration using magnetic beads improves ultrasensitive schistosomiasis diagnostic and eliminates need for well-equipped laboratory in low-resource settings. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: Christine F. Markwalter Source Type: research

Towards a quantum cascade laser-based implant for the continuous monitoring of glucose
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01382A, PaperKatharina Isensee, Niklas M üller, Annemarie Pucci, Wolfgang Petrich Continuous glucose monitoring enables an improved disease management for people with diabetes. However, state-of-the-art, enzyme-based, minimally invasive sensors loose their sensitivity over time and have to be replaced periodically. Here,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: Katharina Isensee Source Type: research

Simple Colorimetric Sensor for the Detection of Moisture in Organic Solvents and Building Materials: Applications in Rewritable Paper and Fingerprint Imaging
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01042K, PaperPawan Kumar, Amrita Ghosh, Amilan Jose Devadoss A simple off-the-shelf dye molecule 1,4-dihydroxy-9,10-anthraquinone or quinizarin (1) has been investigated for the effective detection of moisture in organic solvents and building materials. Anion-induced deprotonation of1 to1.F... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 17, 2018 Category: Chemistry Authors: Pawan Kumar Source Type: research

A new mitochondria-targeted ratiometric fluorescent probe based on diketopyrrolopyrrole for imaging endogenous HOCl in living cells
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01469H, PaperXiaoxu Xie, Jian Wang, Yongchao Yan, Xiao Zhang, Chenchen Liu, Ji Yang, Jianli Hua Ratiometric fluorescent probe (PTZ-TDPP) for HOCl detecting based on diketopyrrolopyrrole (DPP) and phenothiazine platform was designed and synthesized.PTZ-TDPP could target mitochondria and successfully applied in detecting endogenous HOCl in living RAW 264.7 cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 16, 2018 Category: Chemistry Authors: Xiaoxu Xie Source Type: research

A sensitive and fast responsive fluorescent probe for imaging hypoxic tumors
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01472H, PaperLei Zhang, Xue Shan, Leilei Guo, Jikang Zhang, Junliang Ge, Qing Jiang, Xinghai Ning Nitroreductase activities are positively associated with the hypoxic level of tumors, making it an attractive target for tumor detection. Herein, we have developed a 2,5-bis(methylsulfinyl)-1,4-diaminobenzene based probe (BBP), which is... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 16, 2018 Category: Chemistry Authors: Lei Zhang Source Type: research

“On-off-on” fluorescent probes based on nitrogen-doped carbon dots for hypochlorite and bisulfite detection in living cells
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01585F, PaperRuoming Wang, Ruixia Wang, Dongyan Ju, Wei Lu, Chunzhu Jiang, Xueru Shan, Qian Chen, Guoying Sun Although hypochlorite (ClO-) and bisulfite (HSO3-) play important roles in the biological immune system and the aging process of living organisms, they are also classified as the third type of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 16, 2018 Category: Chemistry Authors: Ruoming Wang Source Type: research

Ultrasmall Black Phosphorus Quantum Dots: Synthesis, Characterizaton, and Application in Cancer Treatment
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01612G, PaperMingqian Wang, Ying Liang, Yajun Liu, Guohong Ren, Zhicheng Zhang, Shishan Wu, Jian Shen Black phosphorus quantum dots (BPQDs), because of their unique advantages, are gaining popularity of applying in various fields. For biomedical applications, good biosafety is a prerequisite for their use in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 16, 2018 Category: Chemistry Authors: Mingqian Wang Source Type: research

In situ paper-based 3D cell culture for rapid screening the anti-melanogenic activity
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01725E, PaperNaricha Pupinyo, Moragot Chatatatikun, Anchalee Chiabchalard, Wanida Laiwattanapaisal Recently, paper has gained traction in the biotechnology research field due to its ability to be a substrate for 3D cell culture. In this work, we demonstrate the application of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 16, 2018 Category: Chemistry Authors: Naricha Pupinyo Source Type: research

Solvent directed selective and sensitive fluorescence detection of target ions using a coumarin –pyridine probe
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01736K, PaperYiting Xie, Wenjing Cheng, Bing Jin, Chaogen Liang, Yubin Ding, Weihua Zhang The solvatochromic properties of a coumarin –pyridine probe were utilized as a cheap and effective way for designing fluorescent probes for Mg2+ and PPi with high selectivity and nanomolar level sensitivity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 15, 2018 Category: Chemistry Authors: Yiting Xie Source Type: research

AIE active piperazine appended naphthalimide-BODIPYs: Photophysical properties and applications in live cell lysosomal tracking
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01390J, PaperBhupendra Kumar Dwivedi, Roop Shikha Singh, Afsar Ali, Vinay Sharma, Shaikh M. Mobin, Shankar Pandey Piperazine appended naphthalimide-BODIPY (NPB1 NPB4) exhibiting solvato-chromism and aggregation induced emission with large Stokes shift (up to 146 nm) has been described. Separation of naphthalimide and BODIPY fluorophores by piperazine in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 15, 2018 Category: Chemistry Authors: Bhupendra Kumar Dwivedi Source Type: research

Conductometric immunoassay of alpha-fetoprotein in sera of liver cancer patients using bienzyme-functionalized nanometer-sized silica beads
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01791C, PaperJiaming Liang, Jin Wang, Luwei Zhang, Sijia Wang, Cuiping Yao, Zhenxi Zhang A conductometric immunoassay protocol was designed for sensitive detection of liver cancer biomarker, alpha-fetoprotein (AFP), in biological fluids by using enzyme-conjugated nanometer-sized enzyme-doped silica beads. Initially, urease molecules were doped... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 13, 2018 Category: Chemistry Authors: Jiaming Liang Source Type: research

Optimizing Decision Tree Structures for Spectral Histopathology (SHP)
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01303A, PaperXinying Mu, Mark Kon, Ay şegül Ergin, Stan Remiszewski, M Diem This paper reviews methods to arrive at optimum decision tree or label tree structures to analyze large SHP data sets. Supervised methods of analysis can utilize either sequential or (flat)... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 13, 2018 Category: Chemistry Authors: Xinying Mu Source Type: research

Near-infrared fluorescent probe for monitoring Leucine aminopeptidase in living cells
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01486H, PaperFeiyi Wang, Yun Chai, Yuting Gao, Huiwen Xiong, Lv Wanqian, Guichun Yang, Cuifen Lu, Junqi Nie, Chao Ma, Zuxing Chen, Jun Ren Leucine aminopeptidase (LAP), one of the important cancer-related biomarkers, is significantly over-expressed in many malignant tumor cells. Developing an effective fluorescent probe for high-specific and in-situ trapping of endogenous LAP... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Feiyi Wang Source Type: research

Cationic polymer-based plasmonic sensor array that discriminates proteins
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01360H, PaperHongyan Xi, Xin Li, Qingyun Liu, Zhengbo Chen Breaking the restrictions of the lock-and-key sensing strategy which relies only on the most dominant interactions between the sensing element and target, here, we develop a colorimetric sensor array with three kinds of cationic polymers (polydiallyl dimethylammonium chloride (PDDA), chitosan (CTS), and cetyltrimethylammonium bromide (CTAB)) as nonspecific receptors. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistr...
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Hongyan Xi Source Type: research

Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01341A, PaperGodwin Chukwuebuka Ajaezi, Max Eisele, Fabio Contu, Sadhana Lal, Aline Rangel-Pozzo, Sabine Mai, Kathleen Margaret Gough Recent super-resolution fluorescence microscopy (3D-Structured Illumination Microscopy, 3D-SIM) studies have revealed significantly altered nuclear organization between normal lymphocyte nuclei and those of classical Hodgkin ’s Lymphoma. Similar changes have been found... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Godwin Chukwuebuka Ajaezi Source Type: research

Confocal Raman micro-spectral evidence and physicochemical evaluation of triamterene salts
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01579A, PaperBo Peng, Zaiyong Zhang, Jian-Rong Wang, Meiqi Li, Qi Zhang, Xuefeng Mei Discrimination of active pharmaceutical ingredients (APIs) existing as neutral molecule or salts is essential and complicated. However, the discrimination of pharmaceutical salts by confocal Raman micro-spectroscopy remains relatively poorly understood.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Bo Peng Source Type: research

Recent advances in single-cell analysis by mass spectrometry
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01190G, Critical ReviewLei Yin, Zhi Zhang, Yingze Liu, Yin Gao, Jingkai Gu Cells are the most basic structural units that play vital roles in the functioning of living organisms. Analysis of the chemical composition and content of a single cell plays a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Lei Yin Source Type: research

Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) in vivo
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01860J, CommunicationFay Nicolson, Lauren E Jamieson, Samuel Mabbott, Konstantinos Plakas, Michael Detty, Duncan Graham, Neil Shand, Karen Faulds Resonant chalcogenpyrylium nanotags demonstrate an exceptional surface enhanced Raman scattering (SERS) performance for use in SORS applications. Using SESORS, nanotags modified with a chalcogenpyrylium dye were observed at concentrations as... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 12, 2018 Category: Chemistry Authors: Fay Nicolson Source Type: research

Carbon nanodot aqueous binding phase-based diffusive gradients in thin films device for measurement of dissolved copper and lead species in the aquatic environment
Analyst, 2018, Advance Article DOI: 10.1039/C8AN00612A, PaperNan You, Zhong-Ming Feng, Yun Wang, Hong-Tao Fan, Ting Sun A reliable method for the determination of dissolved Cu2+ and Pb2+ species in watervia a diffusive gradient in thin films (DGT) device using water-soluble carbon nanodots (CD) as the binding agent was developed (CD-DGT). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 11, 2018 Category: Chemistry Authors: Nan You Source Type: research

A green emissive carbon-dot-based sensor with diverse responsive manners for multi-mode sensing
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01552J, PaperXiaohua Pan, Yan Zhang, Xiaobo Sun, Wei Pan, Jinping Wang Since different quenching mechanisms can endow carbon dots (CDs) with diverse responsive manners, multi-mode sensing, therefore, will be achieved by one carbon-dot-based sensor. In this work, green emissive CDs were... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 11, 2018 Category: Chemistry Authors: Xiaohua Pan Source Type: research

DNA microarray analysis using a smartphone to detect the BRCA-1 gene
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01020J, PaperAlisha Prasad, Syed Mohammad Abid Hasan, Steven Grouchy, Manas Ranjan Gartia DNA microarrays are used to examine changes in gene expression of a large number of genes simultaneously by fluorescent labeling of complementary DNAs (cDNAs). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Alisha Prasad Source Type: research

Biochemical alterations of Candida albicans during the phenotypic transition from yeast to hyphae captured by Fourier transform mid-infrared-attenuated reflectance spectroscopy
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01452C, PaperQin-Yin Shi, Cristiane Rodrigues S. C âmara, Vicki Schlegel The first study that applies FTIR spectroscopy to monitor the biochemical modification ofCandida albicans during the transition from a benign yeast to virulent hyphae using multiple spectral analyses. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Qin-Yin Shi Source Type: research

Paper-based Transwell Assays: An Inexpensive Alternative to Study Cellular Invasion
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01157E, PaperRachael M. Kenney, Adam Loeser, Nathan A. Whitman, Matthew Ryen Lockett Cellular movement is essential in the formation and maintenance of healthy tissues as well as in disease progression such as tumor metastasis. In this work, we describe a paper-based Transwell... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Rachael M. Kenney Source Type: research

Monitoring individual cell-signaling activity using combined metal-clad waveguide and surface-enhanced fluorescence imaging
Analyst, 2018, Advance Article DOI: 10.1039/C8AN00911B, PaperThomas S öllradl, Kevin Chabot, Ulrike Fröhlich, Michael Canva, Paul G. Charette, Michel Grandbois Validation of a combined metal-clad waveguide and surface enhanced fluorescence imaging platform for live cell imaging. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Thomas S öllradl Source Type: research

Imaging Nucleus Viscosity and G-quadruplex DNA in Living Cells by a Nucleus-Targeting Two-Photon Fluorescent Probe
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01643G, PaperWan Sun, Jing-Xue Cui, Le-Le Ma, Zhong-Lin Lu, Bing Gong, Lan He, Ruibing Wang A two-photon fluorescent probe, TP-2Bz, was designed, synthesized and exhibited good targeting capabilities toward cell nuleus. In particular, TP-2Bz demonstrated a high selectivity to both G-quadruplex DNA and viscosity inside... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Wan Sun Source Type: research

Smartphone-based Analytical Biosensors
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01269E, Critical ReviewXiwei Huang, Dandan Xu, Jin Chen, Jixuan Liu, Yangbo Li, Jing Song, Xing Ma, Jinhong Guo The traditional analytical biosensor instruments are relatively bulky, expensive, and not easy to handle, thus their applications are largely limited in resource-limited settings. The recent development of microfluidic lab-on-a-chip (LOC)... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Xiwei Huang Source Type: research

Fabrication and evaluation of molecularly imprinted magnetic nanoparticles for selective recognition and magnetic separation of lysozyme in human urine
In this study, lysozyme-based magnetic molecularly imprinted polymers (Lyz-MMIPs) for selective recognition and magnetic separation of lysozyme in human urine were prepared via surface imprinting technology. The morphology and structure... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Zulei Zhang Source Type: research

A Novel Paper-based Colorimetry Device for the Determination of the Albumin to Creatinine Ratio
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01122B, PaperSudkate Chaiyo , Kurt Kalcher, Amara Apilux, Orawon Chailapakul, Weena Siangproh A novel paper-based analytical device (PAD) was fabricated and developed for the simple and rapid determination of the albumin to creatinine ratio (ACR) in urine samples. The detection was based... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 10, 2018 Category: Chemistry Authors: Sudkate Chaiyo Source Type: research

A novel mitochondrial-targeting near-infrared fluorescent probe for imaging γ-glutamyl transpeptidase activity in living cells
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01460D, PaperHaijuan Liu, Feng Liu, Fenglin Wang, Ru-Qin Yu, Jian-Hui Jiang A mitochondrial-targeting near infrared fluorescent probe with high sensitivity, excellent selectivity and desirable response rate is designed for GGT. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 9, 2018 Category: Chemistry Authors: Haijuan Liu Source Type: research

A dual chemosensor for Cu2+ and Hg2+ based on a rhodamine-terminated water-soluble polymer in 100% aqueous solution
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01130C, PaperGuang Li, Liping Bai, Farong Tao, Aixia Deng, Liping Wang A dual chemosensor based on rhodamine-terminated PEG was developed for the simultaneous selective detection of Cu2+ and Hg2+ in water. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Guang Li Source Type: research

A novel and accurate microfluidic assay of CD62L in bladder cancer serum samples
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01463A, PaperGayatri S. Phadke, Jennifer E. Satterwhite-Warden, Dharamainder Choudhary, John A. Taylor, James F. Rusling A magnetic bead-based, microfluidic immunoarray of CD62L can distinguish between low- and high-grade bladder cancer tumors. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Gayatri S. Phadke Source Type: research

Raman spectroscopic analysis of High Molecular Weight Proteins in solution – considerations for sample analysis and data pre-processing
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01701H, PaperDrishya Rajan Parachalil, Brenda Brankin, Jennifer McIntyre, Hugh Byrne Analysis of proteins present in the blood stream can potentially deliver crucial information on patient health and indicate the presence of numerous pathologies. Current analytical techniques can, however, be costly... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Drishya Rajan Parachalil Source Type: research

Graphene, electrospun and granular activated carbon membranes for eliminating heavy metals, pesticides and bacteria in water and wastewater treatment processes.
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN00922H, Critical ReviewPiumie Rajapaksha, Shaneel Chandra, Aoife Power, James Chapman The availability of safe water has an significant impact on all parts of society, its growth and sustainability, both politically and socioeconomically. Consequently, the preservation of water and wastewater treatment... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Piumie Rajapaksha Source Type: research

Logical MS/MS Scans: A New Set of Operations for Tandem Mass Spectrometry
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01661E, PaperDalton Thomas Snyder, Lucas Szalwinski, Mitch Wells, R Graham Cooks A new set of operations for tandem mass spectrometry in a linear ion trap is described. Logical MS/MS operations categorize compounds in mixtures based on characteristic structural features as revealed... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Dalton Thomas Snyder Source Type: research

Investigations on the Interface of Nucleic Acid Aptamers and Binding Targets
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01467A, MinireviewShundong Cai, Jian hua Yan, hongjie xiong, Yanfei Liu, Dongming Peng, Zhenbao Liu Nucleic acid aptamers are single-stranded DNA or RNA with 20-100 nucleotides in length that can specifically bind to target molecules via formed three-dimensional structures, which have attracted substantial scientific interest.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Shundong Cai Source Type: research

Sensor Arrays Made by Self-Organized Nanoreceptors for Detection and Discrimination of Carboxylate Drugs
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01756E, PaperXiaohuan Sun, Ping Liu, Fabrizio Mancin Nanoreceptors capable of recognizing amphiphilic organic carboxylates have been obtained by exploiting the self-organization properties of monolayer protected gold nanoparticles. Affinity and selectivity for the target compounds can be modulated... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Xiaohuan Sun Source Type: research

Fabrication of 3D continuous-flow reverse-transcription polymerase chain reaction microdevice integrated with on-chip fluorescence detection for semi-quantitative assessment of gene expression
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01739E, PaperQuang Nghia Pham, Kieu The Loan Trinh, Nguyen Khoi Song Tran, Tae sik Park, Nae Yoon Lee We fabricate a three-dimensional (3D) microdevice operated with minimal peripheral accessories, including a portable pump for semi-automated sample delivery and a single heater for temperature control, for performing reverse transcription... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Quang Nghia Pham Source Type: research

Single-Molecule DNA Visualization Using AT-specific Red and Non-specific Green DNA-Binding Fluorescent Proteins
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01426D, PaperKyubong Jo, Jihyun Park, Seunghyun Lee, Nabin Won, Eunji Shin, Soo-hyun Kim, Min-young Chun, Jungyeun Gu, Gun Young Jung, Kwang-il Lim The recent advances in the single cell genome analysis are generating a considerable amount of novel insights into complex biological systems. However, there are still technical challenges because each cell... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 8, 2018 Category: Chemistry Authors: Kyubong Jo Source Type: research

Qualitative analysis of antibody –drug conjugates (ADCs): an experimental comparison of analytical techniques of cysteine-linked ADCs
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Malin K ällsten, Rafael Hartmann, Konstantin Artemenko, Sara Bergström Lind, Fredrik Lehmann, Jonas Bergquist Four different cysteine linked antibody-drug conjugates (ADCs) consisting of Trastuzumab-vc-MMAE were analysed with four common analytical techniques with respect to drug-to-antibody ratio (DAR) and molecular weight. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 6, 2018 Category: Chemistry Authors: Malin K ällsten Source Type: research

Dual purpose fibre – SERS pH sensing and bacterial analysis
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Holly Fleming, Sarah McAughtrie, Bethany Mills, Michael G. Tanner, Angus Marks, Colin J. Campbell A way to incorporate SERS nanosensors on the end of an optical fibre that also allows for the extraction of bacterial samples. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 6, 2018 Category: Chemistry Authors: Holly Fleming Source Type: research

A G-triplex based molecular beacon for label-free fluorescence “turn-on” detection of bleomycin
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01208C, PaperLin Ma, Xue Han, Lian Xia, Rong-Mei Kong, Fengli Qu A facile and label-free G-triplex based molecular beacon (G3MB) sensing system was constructed for fluorescence “turn-on” detection of BLM. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 5, 2018 Category: Chemistry Authors: Lin Ma Source Type: research

Green, fast, and large-scale synthesis of highly fluorescent Au nanoclusters for Cu2+ detection and temperature sensing
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01617H, PaperYunxiao Jia, Tianxia Sun, Yingnan Jiang, Weiyi Sun, Yu Zhao, Jingwei Xin, Yiting Hou, Wensheng Yang A rapid sonochemical route is used for green, fast, and large-scale synthesis of highly fluorescent Au nanoclusters for Cu2+ and temperature sensing. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 5, 2018 Category: Chemistry Authors: Yunxiao Jia Source Type: research

Highly sensitive and multiplexed miRNA analysis based on digitally encoded silica microparticles coupled with RCA-based cascade amplification
Analyst, 2018, Advance Article DOI: 10.1039/C8AN01393D, PaperShengquan Liu, Han Fang, Chengjiao Sun, Nana Wang, Jiong Li Multiple miRNA sensitive analysis by coupling digitally encoded silica microparticles with RCA-based cascade amplification. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 5, 2018 Category: Chemistry Authors: Shengquan Liu Source Type: research

A ratiometric fluorescent BODIPY-based probe for rapid and highly sensitive detection of cysteine in human plasma
Analyst, 2018, Accepted Manuscript DOI: 10.1039/C8AN01438H, PaperNannan Wang, Yue Wang, Jinhua Gao, Xin Ji, Jinling He, Jian Zhang, Weili Zhao Biological thiols, especially low molecular weight thiols, including cysteine (Cys), homocysteine (Hcy) and glutathione (GSH) occupied a pivotal role in physiological and pathological sysems. Thus, the detection of biothiols is... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - October 5, 2018 Category: Chemistry Authors: Nannan Wang Source Type: research