Romanian Journal of Morphology and Embryology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Obliterative foam-cell arteriopathy. A unifying concept embracing several entities previously described as radiation, decidual, transplant, and intratumoral-associated arteriopathy
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):457-466. doi: 10.47162/RJME.64.4.01.ABSTRACTThis review article aimed to postulate the existence of a specific arterial injury having as its histological hallmark a collection of macrophages loaded with lipids in the intima of small-sized and medium-sized arteries causing narrowing or complete obstruction. The proposal is made that a series of previously described entities, such as ionizing radiation arteriopathy, acute atherosis (foam-cell decidual arteriopathy), transplant chronic arteriopathy of solid organ allografts, and intratumoral-associated foam-cell arteriopathy constitut...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Jos é Fernando Val-Bernal Marta Mar ía Mayorga Carlos Bercebal Mar ía Luisa Cagigal Source Type: research

Humps and bumps of head: review of meningiomas of the scalp
This study highlights the importance of immunohistochemistry in the differential diagnosis of skin lesions located on the scalp.PMID:38184826 | PMC:PMC10863692 | DOI:10.47162/RJME.64.4.02 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Elena Porumb-Andrese Claudia Florida Costea Georgiana Macovei Gabriela Floren ţa Dumitrescu Lauren ţiu Andrei Blaj Iulian Prutianu Andrei Ionu ţ Cucu Source Type: research

Autoimmune encephalitis and paraneoplastic encephalitis: difficulties in diagnosis and management in the ICU
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):475-482. doi: 10.47162/RJME.64.4.03.ABSTRACTAutoimmune encephalitis (AIE) represents a category of relatively newly described neurological disorders associated with an increasing prevalence, a significant impact on the healthcare system, and a high rate of intensive care unit (ICU) admission. This category of diseases often requires prompt treatment, even before a definitive diagnosis is established. In the ICU, patients present with nonspecific signs and symptoms for AIE, which pose challenges in both management and diagnosis. Patients frequently exhibit dysautonomia, severe physi...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Mihaela Livia Agapie Florin Tudor Borjog Clementina Oana Dumitra şcu Rare ş Prăjescu Mihai Popescu Carmen Orban Source Type: research

Improvement of carotid atherosclerosis and peripheral artery disease after hepatitis C virus eradication by direct-acting antivirals
CONCLUSIONS: Our research highlights the beneficial effect of viral eradication on both carotid atherosclerosis and PAD, especially in those with advanced fibrosis and cirrhosis.PMID:38184828 | PMC:PMC10863684 | DOI:10.47162/RJME.64.4.04 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Tudor Cuciureanu Carol Stanciu Robert Radu N ăstasă Larisa Ermina Stratina Horia Octav Minea Ioan Sebastian Zenovia C ătălin Sfarti Cristina Maria Muzica Laura Huiban Remus Theodor Stafie Ana Maria Singeap Ştefan Chiriac Eliza Camelia Cojocariu Irina Source Type: research

In vitro effects of heparin-binding epidermal growth factor on adhesion stage of implantation
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):493-500. doi: 10.47162/RJME.64.4.05.ABSTRACTA member of the epidermal growth factor (EGF) family, the heparin-binding EGF (HB-EGF) is expressed in the uteri of both humans and mice during the implantation process. To study the effects of HB-EGF on adhesion stage, we developed an in vitro implantation model employing Ishikawa cell line and JAR cell line, which may attach to Ishikawa cells. For 1, 6, 12, and 24 hours, co-cultures of JAR spheroids grown on Ishikawa monolayers were treated with 1, 10, and 100 ng∕mL doses of HB-EGF. Using immunocytochemistry and Western blot analysis,...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Burcu Biltekin Ayhan Bilir Ismail Seckin Gozde Erkanli Senturk Source Type: research

Incidental carcinoma of the prostate in cystoprostatectomy specimens - is it always a toothless lion?
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):501-507. doi: 10.47162/RJME.64.4.06.ABSTRACTIncidental prostate carcinoma (iPC) is a subject of debate concerning its definition, incidence, biology, diagnosis, staging, and treatment. The present study aimed to assess the incidence and main clinical-morphological characteristics of iPC identified in radical cystoprostatectomy (RCP) specimens over a 5-year period. Using the database of the Urology and Pathology Departments, we identified all patients with bladder carcinomas (BCs) who underwent RCP within a 5-year frame time. We selected only those patients with synchronous BC and p...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Vlad Dema Alexei Croitor Andreea Floruncu ţ Sorin Dema Tiberiu R ăzvan Bardan Sorina Maria T ăban Robert Alexandru Barna Bianca Roxana Natar âş Alin Adrian Cump ănaş Source Type: research

Clinicopathological characteristics and prognostic factors of atypical meningiomas with bone invasion: a retrospective analysis of nine cases and literature review
CONCLUSIONS: Our study emphasizes the importance of a thorough histopathological examination of the surgical specimen, which can provide significant data for the assessment of the progression of an AM [World Health Organization (WHO) grade 2] with bone invasion. AM infiltration in adjacent bone and muscle increases the rate of tumor recurrence and decreases PFS over a follow-up period of 60 months.PMID:38184831 | PMC:PMC10863686 | DOI:10.47162/RJME.64.4.07 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Andrei Ionu ţ Cucu Claudia Florida Costea Georgiana Macovei Gabriela Floren ţa Dumitrescu Anca Sava Lauren ţiu Andrei Blaj Iulian Prutianu Elena Porumb-Andrese Cristina Gena Dasc ălu Mihaela Co şman Ion Poeat ă Şerban Turliuc Source Type: research

Symptomatic pericardial cysts and dilemmas in their diagnosis
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):517-525. doi: 10.47162/RJME.64.4.08.ABSTRACTPericardial cysts (PCs) or pleuropericardial cysts are rare congenital mediastinal lesions with an approximate incidence of one in 100 000 persons. Usually, they are asymptomatic, being incidentally discovered during a routine chest imaging examination or an autopsy exam. The study involved a retrospective evaluation of clinicopathological findings in a 6-year series of PCs, treated in the Clinic of Pulmonary Diseases, IaÅŸi, Romania. A group of five cases of PCs, four females and one male, were evaluated. All patients displayed different...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Adriana Grigora ş Cornelia Am ălinei Irina Draga C ăruntu Constantin Cristian Grigora ş Irina Rodica Chiseli ţă Radu Adrian Cri şan-Dabija Source Type: research

Post-COVID-19 enterocolitis - a cause of rebellious diarrhea, acute abdomen and liver failure
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):527-533. doi: 10.47162/RJME.64.4.09.ABSTRACTCurrently, worldwide, the coronavirus disease 2019 (COVID-19) pandemic, which first appeared in Wuhan, China, in December 2019, is capsizing the medical system and turning the attention of the entire healthcare system through the many aspects it presents, both from a pathophysiological and from a semiological view, insufficiently studied aspects. With a high rate of morbidity and mortality, the COVID-19 pandemic was initially observed as a pathology leading to a severe acute respiratory syndrome, but over time gastrointestinal and hepatic...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cosmin Vasile Obleag ă Rukie Ana Maria Ahmet Dan Nicolae Florescu Drago ş Marian Popescu Cristian Me şină Liliana Streba Cristin Constantin Vere Cristian Constantin Source Type: research

Histological findings for the absorption of small and large liposomes - the basis of future drug delivery and contrast media systems
CONCLUSIONS: Frozen-section fluorescence microscopy is a reliable technique for visualization of liposome absorption. Based on the size of these nanosystems, we revealed significant absorption for small liposomes in testicles, liver, heart, and gum, and for large liposomes mainly in the liver, compared with the control groups. The study advocates for the usage of liposomes for medical purposes, based on their absorption proprieties.PMID:38184834 | PMC:PMC10863683 | DOI:10.47162/RJME.64.4.10 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Roxana Florentina Şufaru Cristinel Ionel Stan C ătălina Anişoara Peptu Liviu Ciprian Gavril Drago ş Andrei Chiran Drago ş Valentin Crauciuc Eduard Gabriel Crauciuc Mihaela Adela Iancu Ruxandra Vatavu Codrin Gabriel Lucasievici Ana Maria Dumitrescu A Source Type: research

Time to redefine hyperuricemia? The serum uric acid cut-off level for precipitation might be lower: a pilot study
CONCLUSIONS: The "snowstorm" aspect of the fluid might be the result of an increased level of SUA and more than this, the cut-off level for SUA to precipitate might be lower than the fore used values.PMID:38184835 | PMC:PMC10863690 | DOI:10.47162/RJME.64.4.11 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Ananu Florentin Vreju Cristina Dorina P ârvănescu Adina Turcu- Ştiolică Ştefan Cristian Dinescu Sineta Cristina Firulescu Andreea Lili B ărbulescu Andreea Beatrice Chis ălău R ăzvan Adrian Ionescu Hora ţiu Valeriu Popoviciu Cristina Elena Gofi ŠSource Type: research

The influence of SARS-CoV-2 on the immune system elements and on the placental structure. Clinical, histological and immunohistochemical study
CONCLUSIONS: This study shows that the invasion of SARS-CoV-2 in the placenta can produce significant structural changes, with a decrease in placental vascular density that can have significant implications on proper fetal perfusion. Also, the presence of immunoreactivity at the level of decidua, the placental villi, as well as the chorionic plate proves that the virus can overcome the maternal-fetal barrier. However, in the analyzed cases there were no fetal infections at birth, which may show that local placental factors can be a protective filter for the fetus.PMID:38184836 | PMC:PMC10863699 | DOI:10.47162/RJME.64.4.12 ...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cristina Jana Busuioc Gabriela Camelia Ro şu George Lucian Zoril ă Lauren ţiu Mogoantă Anca Maria Istrate-Ofi ţeru Daniel Pirici Ilona Mihaela Liliac Larisa Iovan Elena Iuliana Anamaria Berbecaru Maria Cristina Com ănescu Sergiu Marian Cazacu Domini Source Type: research

Kaposi's sarcoma of the larynx: case series
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):559-565. doi: 10.47162/RJME.64.4.13.ABSTRACTKaposi's sarcoma (KS) represents a type of cancer that usually arises on the skin and very rarely in other organs. KS-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8) commonly arises in patients with acquired immunodeficiency syndrome (AIDS). Laryngeal involvement of KS is very rare. Our study comprised of three cases with laryngeal KS. All cases were solved through surgical excision of the tumor. Histopathological and immunohistochemistry examinations revealed laryngeal KS. Laryngeal KS should be managed through s...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Mircea Sorin Ciolofan Florin Anghelina Carmen Aurelia Mogoant ă Alexandru Nicolae Vl ăescu Mihaela Roxana Mitroi Alina Nicoleta C ăpitănescu Charoula Florou Anca Maria Istrate-Ofi ţeru Gheorghe Iov ănescu Source Type: research

Zinc-Boron-PLGA biocomposite material: preparation, structural characterization, and in vitro assessment
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):567-577. doi: 10.47162/RJME.64.4.14.ABSTRACTNowadays, the state-of-the-art discoveries in the field of delivery systems for therapeutic purposes have redefined the importance of biocompatible and biodegradable poly(lactic-co-glycolic acid (PLGA) nanocomposites. The study aimed to obtain a biocomposite material, with improved properties of its constituents [zinc-boron (Zn-B) complex and PLGA], by a simple, cost-effective method. The water∕oil∕water double emulsion technique allowed the adjustment of the synthesis parameters, to maximize the degree of Zn-B complex encapsulation. ...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Maria Viorica Cioc îlteu Ion Romulus Scorei Gabriela R ău Claudiu Nicolicescu Andrei Bi ţă Vladimir Lucian Ene Andreea Simionescu Adina Turcu- Ştiolică Venera Cristina Dinescu Johny Neam ţu Lauren ţiu Mogoantă George Dan Mogo şanu Source Type: research

Intracardiac mass presenting as acute myocardial infarction
Rom J Morphol Embryol. 2023 Oct-Dec;64(4):579-585. doi: 10.47162/RJME.64.4.15.ABSTRACTCardiac tumors, although rare, present intricate diagnostic and therapeutic challenges, necessitating timely intervention for optimal patient outcomes. This case report focuses on a 65-year-old woman admitted with chest pain and loss of consciousness, ultimately diagnosed with a left ventricular cardiac myxoma. The patient's presentation mimicked acute coronary syndrome, highlighting the diagnostic complexity associated with cardiac tumors. Advanced imaging modalities, including transthoracic echocardiography, computed tomography, and inv...
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Diana Ruxandra H ădăreanu Mihaela Corina Berceanu Roxana Daniela Stroescu Sebastian Militaru Constantin Militaru C ălin Dinu Hădăreanu Victor Cornel Raicea Nelu Irinel Şoşea Elian Octavian Boldu Oana Cristina Munteanu Mirea R ăzvan Ilie Radu Ioana Source Type: research