Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
CONCLUSIONS: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.PMID:38530204 | DOI:10.4193/Rhin23.487 (Source: Rhinology)
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: S Uyttebroek C Claeyssens M Jorissen L Dupont L Van Gerven Source Type: research
Taste loss in COVID-19 - psychophysical evidence supporting a low prevalence
Rhinology. 2024 Mar 26. doi: 10.4193/Rhin24.040. Online ahead of print.ABSTRACTMuch - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9% (1), which is in a similar range as COVID-19 related smell loss. However, most of these publications rely solely on patients' self-reports. Only few studies used validated psychophysical tests to specifically address olfaction and gustation. Especially for gustation, it is evident that subjective reporting does not correlate well with more objective psychophysical findings, ...
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: C A Hintschich S Le Bon E Trecca S Saussez T Hummel Source Type: research
Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
CONCLUSIONS: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.PMID:38530204 | DOI:10.4193/Rhin23.487 (Source: Rhinology)
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: S Uyttebroek C Claeyssens M Jorissen L Dupont L Van Gerven Source Type: research
Taste loss in COVID-19 - psychophysical evidence supporting a low prevalence
Rhinology. 2024 Mar 26. doi: 10.4193/Rhin24.040. Online ahead of print.ABSTRACTMuch - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9% (1), which is in a similar range as COVID-19 related smell loss. However, most of these publications rely solely on patients' self-reports. Only few studies used validated psychophysical tests to specifically address olfaction and gustation. Especially for gustation, it is evident that subjective reporting does not correlate well with more objective psychophysical findings, ...
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: C A Hintschich S Le Bon E Trecca S Saussez T Hummel Source Type: research
Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
CONCLUSIONS: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.PMID:38530204 | DOI:10.4193/Rhin23.487 (Source: Rhinology)
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: S Uyttebroek C Claeyssens M Jorissen L Dupont L Van Gerven Source Type: research
Taste loss in COVID-19 - psychophysical evidence supporting a low prevalence
Rhinology. 2024 Mar 26. doi: 10.4193/Rhin24.040. Online ahead of print.ABSTRACTMuch - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9% (1), which is in a similar range as COVID-19 related smell loss. However, most of these publications rely solely on patients' self-reports. Only few studies used validated psychophysical tests to specifically address olfaction and gustation. Especially for gustation, it is evident that subjective reporting does not correlate well with more objective psychophysical findings, ...
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: C A Hintschich S Le Bon E Trecca S Saussez T Hummel Source Type: research
Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
CONCLUSIONS: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.PMID:38530204 | DOI:10.4193/Rhin23.487 (Source: Rhinology)
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: S Uyttebroek C Claeyssens M Jorissen L Dupont L Van Gerven Source Type: research
Objective nasal airflow measures in relation to subjective nasal obstruction, trigeminal function, and olfaction in patients with chronic rhinosinusitis
CONCLUSION: The perception of nasal obstruction does not only depend on nasal airflow, but may also be modulated by trigeminal function and other factors. Thus, the role of objective nasal airflow measures as a sole method of functional nasal obstruction assessment in CRS remains limited.PMID:38507726 | DOI:10.4193/Rhin23.270 (Source: Rhinology)
Source: Rhinology - March 20, 2024 Category: ENT & OMF Authors: A K Hernandez C Uhl A Haehner M Cuevas T Hummel Source Type: research
Validation and shortcomings of the most common mouse model of chronic rhinosinusitis with nasal polyps
CONCLUSIONS: With the notable exception of local IgE production, the addition of SEB did not induce additional inflammatory or structural change in the sinuses from mice exposed to and challenged with OVA. This model might represent a model for severe upper airway allergy rather than a specific model of human eCRSwNP.PMID:38497676 | DOI:10.4193/Rhin23.331 (Source: Rhinology)
Source: Rhinology - March 18, 2024 Category: ENT & OMF Authors: A S ánchez-Montalvo M Lecocq E Bouillet B Steelant S Gohy A Froidure D Bullens C Pilette V Hox Source Type: research
Clinical outcomes of functional endoscopic sinus surgery in cystic fibrosis patients - a single centre experience
CONCLUSIONS: There was a demonstrated clinical and symptomatic benefit of ESS in CF patients in this study. Stricter guidelines for indications for ESS need to be established with regards to CF patients who will undergo ESS in the future.PMID:38497762 | DOI:10.4193/Rhin23.057 (Source: Rhinology)
Source: Rhinology - March 18, 2024 Category: ENT & OMF Authors: Y Devabalan R Towning J Magill H Saleh C Rennie Source Type: research
Validation and shortcomings of the most common mouse model of chronic rhinosinusitis with nasal polyps
CONCLUSIONS: With the notable exception of local IgE production, the addition of SEB did not induce additional inflammatory or structural change in the sinuses from mice exposed to and challenged with OVA. This model might represent a model for severe upper airway allergy rather than a specific model of human eCRSwNP.PMID:38497676 | DOI:10.4193/Rhin23.331 (Source: Rhinology)
Source: Rhinology - March 18, 2024 Category: ENT & OMF Authors: A S ánchez-Montalvo M Lecocq E Bouillet B Steelant S Gohy A Froidure D Bullens C Pilette V Hox Source Type: research
