Comparative investigation of transport and deposition of nebulized particles in nasal airways following various middle turbinectomy
CONCLUSIONS: This study is the first to investigate the effect of various surgery scope on drug delivery by transnasal nebulization to the sinonasal cavities. The findings strongly affirm the vast potential of transnasal nebulization as an effective post-FESS treatment option. Moreover, it emphasizes that the drug delivery process via atomizers to the nasal cavity and paranasal sinuses is highly sensitive to the particle size.PMID:38010118 | DOI:10.4193/Rhin23.265 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: R Ma L Tian Y Wang S Sun J Zhang M Lou Z Hu M Gong F Yang G Zheng J Dong Y Zhang Source Type: research
Evidence for a role of metformin in preventing olfactory dysfunction among older adults
CONCLUSIONS: Metformin use is associated with lower odds of OD among individuals with diabetes, suggesting a potential protective effect on olfaction. Future work including a larger sample and additional information on metformin use is needed to establish whether these findings are independent of diabetic control.PMID:38009582 | DOI:10.4193/Rhin23.250 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: S Assi V Vohra W Zhang N S Reed A P Lane M Ramanathan N R Rowan Source Type: research
Determinants of the microbiome spatial variability in chronic rhinosinusitis
CONCLUSIONS: Sampling from the middle meatus is not universally representative of the sinus microbiome. The differences between sites cannot be predicted from the patency of communication pathways between them.PMID:38009901 | DOI:10.4193/Rhin22.423 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: J Szaleniec V Bezshapkin A Krawczyk K Kopera B Zapa ła T Gosiewski T Kosciolek Source Type: research
Comparative investigation of transport and deposition of nebulized particles in nasal airways following various middle turbinectomy
CONCLUSIONS: This study is the first to investigate the effect of various surgery scope on drug delivery by transnasal nebulization to the sinonasal cavities. The findings strongly affirm the vast potential of transnasal nebulization as an effective post-FESS treatment option. Moreover, it emphasizes that the drug delivery process via atomizers to the nasal cavity and paranasal sinuses is highly sensitive to the particle size.PMID:38010118 | DOI:10.4193/Rhin23.265 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: R Ma L Tian Y Wang S Sun J Zhang M Lou Z Hu M Gong F Yang G Zheng J Dong Y Zhang Source Type: research
Evidence for a role of metformin in preventing olfactory dysfunction among older adults
CONCLUSIONS: Metformin use is associated with lower odds of OD among individuals with diabetes, suggesting a potential protective effect on olfaction. Future work including a larger sample and additional information on metformin use is needed to establish whether these findings are independent of diabetic control.PMID:38009582 | DOI:10.4193/Rhin23.250 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: S Assi V Vohra W Zhang N S Reed A P Lane M Ramanathan N R Rowan Source Type: research
Determinants of the microbiome spatial variability in chronic rhinosinusitis
CONCLUSIONS: Sampling from the middle meatus is not universally representative of the sinus microbiome. The differences between sites cannot be predicted from the patency of communication pathways between them.PMID:38009901 | DOI:10.4193/Rhin22.423 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: J Szaleniec V Bezshapkin A Krawczyk K Kopera B Zapa ła T Gosiewski T Kosciolek Source Type: research
Comparative investigation of transport and deposition of nebulized particles in nasal airways following various middle turbinectomy
CONCLUSIONS: This study is the first to investigate the effect of various surgery scope on drug delivery by transnasal nebulization to the sinonasal cavities. The findings strongly affirm the vast potential of transnasal nebulization as an effective post-FESS treatment option. Moreover, it emphasizes that the drug delivery process via atomizers to the nasal cavity and paranasal sinuses is highly sensitive to the particle size.PMID:38010118 | DOI:10.4193/Rhin23.265 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: R Ma L Tian Y Wang S Sun J Zhang M Lou Z Hu M Gong F Yang G Zheng J Dong Y Zhang Source Type: research
Evidence for a role of metformin in preventing olfactory dysfunction among older adults
CONCLUSIONS: Metformin use is associated with lower odds of OD among individuals with diabetes, suggesting a potential protective effect on olfaction. Future work including a larger sample and additional information on metformin use is needed to establish whether these findings are independent of diabetic control.PMID:38009582 | DOI:10.4193/Rhin23.250 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: S Assi V Vohra W Zhang N S Reed A P Lane M Ramanathan N R Rowan Source Type: research
Determinants of the microbiome spatial variability in chronic rhinosinusitis
CONCLUSIONS: Sampling from the middle meatus is not universally representative of the sinus microbiome. The differences between sites cannot be predicted from the patency of communication pathways between them.PMID:38009901 | DOI:10.4193/Rhin22.423 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: J Szaleniec V Bezshapkin A Krawczyk K Kopera B Zapa ła T Gosiewski T Kosciolek Source Type: research
Comparative investigation of transport and deposition of nebulized particles in nasal airways following various middle turbinectomy
CONCLUSIONS: This study is the first to investigate the effect of various surgery scope on drug delivery by transnasal nebulization to the sinonasal cavities. The findings strongly affirm the vast potential of transnasal nebulization as an effective post-FESS treatment option. Moreover, it emphasizes that the drug delivery process via atomizers to the nasal cavity and paranasal sinuses is highly sensitive to the particle size.PMID:38010118 | DOI:10.4193/Rhin23.265 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: R Ma L Tian Y Wang S Sun J Zhang M Lou Z Hu M Gong F Yang G Zheng J Dong Y Zhang Source Type: research
Evidence for a role of metformin in preventing olfactory dysfunction among older adults
CONCLUSIONS: Metformin use is associated with lower odds of OD among individuals with diabetes, suggesting a potential protective effect on olfaction. Future work including a larger sample and additional information on metformin use is needed to establish whether these findings are independent of diabetic control.PMID:38009582 | DOI:10.4193/Rhin23.250 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: S Assi V Vohra W Zhang N S Reed A P Lane M Ramanathan N R Rowan Source Type: research
Determinants of the microbiome spatial variability in chronic rhinosinusitis
CONCLUSIONS: Sampling from the middle meatus is not universally representative of the sinus microbiome. The differences between sites cannot be predicted from the patency of communication pathways between them.PMID:38009901 | DOI:10.4193/Rhin22.423 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: J Szaleniec V Bezshapkin A Krawczyk K Kopera B Zapa ła T Gosiewski T Kosciolek Source Type: research
Comparative investigation of transport and deposition of nebulized particles in nasal airways following various middle turbinectomy
CONCLUSIONS: This study is the first to investigate the effect of various surgery scope on drug delivery by transnasal nebulization to the sinonasal cavities. The findings strongly affirm the vast potential of transnasal nebulization as an effective post-FESS treatment option. Moreover, it emphasizes that the drug delivery process via atomizers to the nasal cavity and paranasal sinuses is highly sensitive to the particle size.PMID:38010118 | DOI:10.4193/Rhin23.265 (Source: Rhinology)
Source: Rhinology - November 27, 2023 Category: ENT & OMF Authors: R Ma L Tian Y Wang S Sun J Zhang M Lou Z Hu M Gong F Yang G Zheng J Dong Y Zhang Source Type: research
Hypereosinophilia during dupilumab treatment in patients with chronic rhinosinusitis with nasal polyps
CONCLUSIONS: Blood eosinophil count (BEC) ≥ 1.5 is transient and usually abates with no therapeutic interventions and BEC ≥ 3.0 is rare. Hypereosinophilic syndrome did not occur and switching to a different biological was rarely employed. A baseline BEC of ≥1.0 can be a reason for extra caution.PMID:37999634 | DOI:10.4193/Rhin23.357 (Source: Rhinology)
Source: Rhinology - November 24, 2023 Category: ENT & OMF Authors: P Kemp R J L van der Lans J J Otten G F J P M Adriaensen L B L Benoist M E Cornet D R Hoven B Rinia V Verkest W J Fokkens S Reitsma Source Type: research
