Immune-related pneumonitis: A differential diagnosis of SARS-CoV-2  pneumonia
CONCLUSION: Pulmonary toxicity secondary to immunotherapy remains a rare but potentially life-threatening side effect. The diagnostic approach requires the elimination of several differential diagnoses (infectious process, tumor progression, other etiologies of interstitial lung disease). This adverse event is reversible and evolution after initiation of corticosteroid therapy is usually favorable.PMID:35906150 | DOI:10.1016/j.rmr.2022.07.001 (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - July 29, 2022 Category: Respiratory Medicine Authors: B Nigen A-L Ch éné R Liberge C Sagan F-X Blanc Source Type: research

Neutrophil plasticity: A new key in the understanding of onco-immunology
Rev Mal Respir. 2022 Jul 20:S0761-8425(22)00257-1. doi: 10.1016/j.rmr.2022.06.007. Online ahead of print.ABSTRACTLung cancer remains the leading cause of cancer mortality in France. Research has shown that immune cells play a major role in tumor growth, angiogenesis and promotion of metastasis. While the density of intra-tumoral adaptive immune cell infiltrate is associated with a favorable prognosis, the presence of polynuclear neutrophils (innate immune cells) is associated in different types of cancer with a poor prognosis. The reviewed studies underline the abundance of intra-tumoral neutrophils involved in tumor progr...
Source: Revue des Maladies Respiratoires - July 23, 2022 Category: Respiratory Medicine Authors: P Mouillot V Witko-Sarsat M Wislez Source Type: research

Alpha1-antitrypsin deficiency: French guidelines … at last !
Rev Mal Respir. 2022 Jul 2:S0761-8425(22)00234-0. doi: 10.1016/j.rmr.2022.06.003. Online ahead of print.NO ABSTRACTPMID:35792000 | DOI:10.1016/j.rmr.2022.06.003 (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - July 6, 2022 Category: Respiratory Medicine Authors: J-F Mornex M Balduyck A Cuvelier V Cottin H Mal Source Type: research