Cushing's syndrome with inhaled corticosteroid: Drug interactions to avoid
We report the clinical case of a 29-year-old woman with a past history of asthma treated with inhaled fluticasone propionate (FP), chronic pulmonary aspergillosis and allergic bronchopulmonary aspergillosis (ABPA) treated with itraconazole (ITZ), and Mycobacterium xenopi infection treated with moxifloxacin (MXF), ethambutol (EMB) and clarithromycin (CLR). Four months after initiation of antibiotic and antifungal medication, the patient contracted Cushing's syndrome. Its etiology consisted in interaction between FP, ITZ and CLR, which led to pronouncedly increased corticosteroid concentrations in circulating plasma cells. F...
Source: Revue des Maladies Respiratoires - September 24, 2023 Category: Respiratory Medicine Authors: M Briard C Godet D Mouren G Weisenburger H Mal J Messika M Salpin T Goletto V Bunel M Veyrier Source Type: research
Interventionnal bronchoscopy for the treatment of tracheobronchomalacia
Rev Mal Respir. 2023 Sep 13:S0761-8425(23)00206-1. doi: 10.1016/j.rmr.2023.07.004. Online ahead of print.ABSTRACTTracheobronchomalacia is usually characterized by more than 50% expiratory narrowing in diameter of the trachea and the bronchi. The expiratory collapse includes two entities: (1) the TBM related to the weakness of the cartilaginous rings, and (2) the Excessive Dynamic Airway Collapse (EDAC) due to the excessive bulging of the posterior membrane. Patients have nonspecific respiratory symptoms like dyspnea and cough. Diagnosis is confirmed by dynamic tests: flexible bronchoscopy and/or computed tomographic scan o...
Source: Revue des Maladies Respiratoires - September 15, 2023 Category: Respiratory Medicine Authors: A M Santos Portela D M Radu I Onorati M Peretti O Freynet Y Uzunhan S Jerbi E Martinod Source Type: research
Remote monitoring: Many hopes, few certainties
Rev Mal Respir. 2023 Sep;40(7):533-534. doi: 10.1016/j.rmr.2023.08.002.NO ABSTRACTPMID:37689434 | DOI:10.1016/j.rmr.2023.08.002 (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - September 9, 2023 Category: Respiratory Medicine Authors: J Gonzalez Bermejo Source Type: research
