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Improved diagnostic accuracy for myocardial perfusion imaging using artificial neural networks on different input variables including clinical and quantification data
ConclusionThe diagnostic accuracy of MPI could be improved by ANN, using clinical and quantification data.ResumenObjetivoLa precisión diagnóstica de la imagen de perfusión miocárdica (IPM) no es óptima para predecir el resultado de la angiografía. El objetivo del presente estudio es investigar la aplicación de la red neuronal artificial (RNA) para integrar los datos clínicos con el resultado y la cuantificación del IPM.MétodosDe 923 pacientes con IPM, se reclutaron 93 que se sometieron a angiografía. Se recogieron los datos clínicos, incluidos los factores de riesgo cardíaco, y se registraron los resultados de...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - June 5, 2019 Category: Nuclear Medicine Source Type: research

Cardiac sympathetic innervation scintigraphy with 123I-meta-iodobenzylguanidine. Basis, protocols and clinical applications in Cardiology
Publication date: Available online 4 June 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): I. Casáns-Tormo, A. Jiménez-Heffernan, V. Pubul-Núñez, R. Ruano-PérezAbstractImaging of cardiac sympathetic innervation is only possible by nuclear cardiology techniques and its assessment is key in the evaluation of and decision-making for patients with cardiac sympathetic impairment. This review includes the basis of cardiac sympathetic scintigraphy with 123I-meta-iodobenzylguanidine (123I-MIBG), recommended protocols, patient preparation, image acquisition and quantification, re...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - June 5, 2019 Category: Nuclear Medicine Source Type: research

Segmentation of gliomas in 18F-Fluorocholine PET/CT. A multiapproach study
ConclusionA great interobserver variability in the tumour segmentation was found. None of the methods was able to segment correctly all the gliomas, probably explained by the wide tumour heterogeneity on 18F-Fluorocholine PET/CT.ResumenObjetivoEl objetivo fue doble, valorar el acuerdo interobservador en la segmentación tumoral y la búsqueda de una metodología fiable y aplicable en la segmentación de gliomas usando PET/TC con 18F-Fluorocolina.Material y métodosSe incluyeron 25 pacientes con glioma, procedentes de un estudio prospectivo no randomizado [FuMeGA (Functional and Metabolic Glioma Analysis)].Se analizó la va...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - June 2, 2019 Category: Nuclear Medicine Source Type: research

Hepatobiliary scintigraphy in the study of complications in adult patients after liver transplant. Description of the experience
ConclusionHepatobiliary scintigraphy is a simple, non-invasive, reliable, current and available form for the early study of biliary complications in patients with liver transplantation. Important hepatocellular dysfunction should be taken into account as a frequent cause of false negative studies.ResumenObjetivoMostrar la experiencia del uso de la gammagrafía hepatobiliar en pacientes con sospecha de complicaciones biliares postrasplante hepático en un centro de alta complejidad.Material y métodoEstudio retrospectivo, observacional y descriptivo. Se incluyeron todos los pacientes consecutivos adultos con trasplante hep�...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 23, 2019 Category: Nuclear Medicine Source Type: research

Melorheostosis: a rare sclerosing bone dysplasia. Usefulness of bone scintigraphy
Publication date: Available online 1 May 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): E.R. Marqués Aparicio, J. Dolado Ardit, A. Crespo-Jara, A. Martínez Caballero, M.A. Antón Leal, J.M. Clavel Claver, M.M. Riera Ayora, J. Verdú Rico (Source: Revista Espanola de Medicina Nuclear e Imagen Molecular)
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 3, 2019 Category: Nuclear Medicine Source Type: research

18F FDG PET/CT imaging of trichoblastoma of the knee
Publication date: May–June 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 38, Issue 3Author(s): Ba D. Nguyen, David J. DiCaudo (Source: Revista Espanola de Medicina Nuclear e Imagen Molecular)
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 3, 2019 Category: Nuclear Medicine Source Type: research

Diagnostic impact of 18F-FDG PET/CT on the management of rare breast carcinomas: apocrine and neuroendocrine carcinomas
ConclusionsThe histopathological ABC subtype group showed different 18F-FDG uptake than the IDC group. Even if 18F-FDG uptake was lower in the PBNEC group than in the other groups, PET/CT showed and adequate performance in detecting primary tumors and metastases. The 18F-FDG PET/CT scan results may contribute to the initial staging and management of ABC and PBNEC patients.ResumenObjetivoEl objetivo fue evaluar el impacto diagnóstico y la estadificación mediante PET/TC con 18F-FDG en carcinomas apocrinos (ABC) y carcinomas neuroendocrinos (PBNEC) y detectar posibles alteraciones en la captación de 18F-FDG según el subti...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - May 3, 2019 Category: Nuclear Medicine Source Type: research

Lymphoscintigraphy for the evaluation of limb lymphatic flow disorders: Report of technical procedural standards from an Italian Nuclear Medicine expert panel
Publication date: Available online 23 April 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Marco Maccauro, Giuseppe Villa, Augusto Manzara, Giulia Anna Follacchio, Gianpiero Manca, Girolamo Tartaglione, Sotirios Chondrogiannis, Lucio Mango, Domenico RubelloAbstractLymphoscintigraphy represents the “gold standard” for diagnosis of lymphedema, but an important limitation is the lack of procedural standardization. The aim of this Italian expert panel was to provide a procedural standard for lymphoscintigraphy in the evaluation of lymphatic system disorders. Topic anaesthet...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - April 24, 2019 Category: Nuclear Medicine Source Type: research

Refining the staging of head and neck tumors. The role of Nuclear Medicine
Publication date: Available online 18 April 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Africa Muxí, Sergi Vidal-Sicart, Isabel Vilaseca (Source: Revista Espanola de Medicina Nuclear e Imagen Molecular)
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - April 19, 2019 Category: Nuclear Medicine Source Type: research

PET/TC imaging with somatostatin analogues for the assessment of neuroendocrine tumours, initial experience
We present two of the first cases of SSA-PET/CT with 68Ga-edotreotide (SomaKit TOC®) performed in our centre. SSA-PET/CT was the test that finally determined the clinical management of both patients.ResumenLa PET con análogos de la somatostatina permite detectar aquellas células con sobreexpresión de receptores de somatostatina, especialmente del subtipo 2 y 5, siendo variable esta detección según el tipo de molécula que se utilice. Esta es la base para su uso en el estudio de los tumores neuroendocrinos (NET), los cuales se caracterizan por presentar una sobreexpresión de estos receptores en más del 80% de los su...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - April 19, 2019 Category: Nuclear Medicine Source Type: research

Role of 18F-FDG-PET/CT in establishing new clinical and therapeutic modalities in lung cancer. A short review
In conclusion, 18F-FDG PET/CT can be considered a highly accurate and reliable method for staging and re-staging lung cancer, and is highly effective in guiding personalised therapies.ResumenEl cáncer de pulmón es una neoplasia maligna bastante común. Un diagnóstico precoz y una estadificación y nueva estadificación confiables, con el objetivo de detectar recaídas tanto locales como distantes, son de suma importancia en la planificación del manejo terapéutico. La evaluación diagnóstica de los pacientes con cáncer de pulmón generalmente incluye imágenes convencionales (radiografía de tórax, TC con contraste,...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - April 5, 2019 Category: Nuclear Medicine Source Type: research

Detection of epileptogenic focus with two new methods of processing of SPECT and PET cerebral images: PET-Analysis and PISCOM
We present the case of an 18-year-old male with epileptic seizures refractory to antiepileptic treatment. Magnetic resonance (MR) showed dysplasia in the posterior right insular cortex. Subtraction of ictal SPECT co-registered to MR (SISCOM) detected a focal increase of uptake in the left fronto-parietal cingulate cortex and 18F-FDG PET showed normal distribution of the radiotracer.The posterior right insula was resected with histopathological results of grade I ganglioglioma according to the World Health Organization classification. The patient made favourable post-surgical progress, and remains seizure-free after 5 years...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - March 29, 2019 Category: Nuclear Medicine Source Type: research

75Se-Homocholic acid taurine scintigraphy (75SeHCAT®), a standard benchmark test in bile acid malabsorption?
Publication date: Available online 19 March 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): A. Baena García, F. Partida Palma, S. García Martínez, M. de Bonilla Candau, M. Pajares VinardellAbstractChronic diarrhea due to bile acid malabsorption (BAM) is an underdiagnosed pathology. Different diagnostic tools are available. However, there is currently no consensus on which of these would be the benchmark test or gold standard. This review evaluates the possibility of using 75Se-taurocholic acid (75SeHCAT®) scintigraphy as a benchmark diagnostic test and its perspective fo...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - March 20, 2019 Category: Nuclear Medicine Source Type: research

Freehand-SPECT with 99mTc-HDP as tool to guide percutaneous biopsy of skeletal lesions detected on bone scintigraphy
ConclusionIn this pilot study, in 86% of the cases freehandSPECT demonstrated good concordance with traditional scintigraphy. A lesion with a SBR of 1.36 or more was suitable for navigation. These high-quality freehandSPECT images supported the future exploration navigation strategies, e.g. guided needle biopsies.ResumenObjetivosDeterminar la factibilidad de la freehandSPECT en la identificación de lesiones óseas con captación de 99mTc-HDP evaluando los datos generados mediante la utilización de sistemas de navegación con realidad aumentada y virtual.Material y métodosSe generaron 21 imágenes 3D utilizando freehandS...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - March 20, 2019 Category: Nuclear Medicine Source Type: research

Sentinel lymph node biopsy in N+ breast cancer with conversion into N0 after neoadjuvant chemotherapy
ConclusionSLNB in breast cancer with conversion into N0 after neoadjuvant treatment is a technique with good results and a low false negative rate.ResumenObjetivoValorar la utilidad de la biopsia selectiva del ganglio centinela (BSGC) en pacientes con carcinoma de mama N+ convertidas a N0 tras recibir quimioterapia neoadyuvante.Material y métodosAnálisis descriptivo incluyendo 16 mujeres diagnosticadas de carcinoma infiltrante de mama con metástasis linfáticas confirmadas por biopsia y portadoras de marcador metálico (MM) en el ganglio patológico. Recibieron quimioterapia neoadyuvante con respuesta radiológica compl...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - March 17, 2019 Category: Nuclear Medicine Source Type: research