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A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil
Rev Inst Med Trop Sao Paulo. 2024 Feb 19;66:e12. doi: 10.1590/S1678-9946202466012. eCollection 2024.ABSTRACTWe conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result fo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Gerusa Figueiredo Francisco Chiaravalloti S érgio Campos Alessandra Cristina Guedes Pellini Alvina Clara Felix Expedito Luna Source Type: research

Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research

Cardiorespiratory optimal point in post-COVID-19 patients: a cross-sectional study
This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Karinne Sim ões da Cruz Santos Gabriela Menezes Gon çalves de Brito Enaldo Vieira de Melo Ant ônio Carlos Sobral Sousa Paulo Ricardo Martins-Filho Milena Dos Santos Barros Campos Source Type: research

A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil
Rev Inst Med Trop Sao Paulo. 2024 Feb 19;66:e12. doi: 10.1590/S1678-9946202466012. eCollection 2024.ABSTRACTWe conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result fo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Gerusa Figueiredo Francisco Chiaravalloti S érgio Campos Alessandra Cristina Guedes Pellini Alvina Clara Felix Expedito Luna Source Type: research

Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research

Cardiorespiratory optimal point in post-COVID-19 patients: a cross-sectional study
This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Karinne Sim ões da Cruz Santos Gabriela Menezes Gon çalves de Brito Enaldo Vieira de Melo Ant ônio Carlos Sobral Sousa Paulo Ricardo Martins-Filho Milena Dos Santos Barros Campos Source Type: research

A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil
Rev Inst Med Trop Sao Paulo. 2024 Feb 19;66:e12. doi: 10.1590/S1678-9946202466012. eCollection 2024.ABSTRACTWe conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result fo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Gerusa Figueiredo Francisco Chiaravalloti S érgio Campos Alessandra Cristina Guedes Pellini Alvina Clara Felix Expedito Luna Source Type: research

Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research

Cardiorespiratory optimal point in post-COVID-19 patients: a cross-sectional study
This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Karinne Sim ões da Cruz Santos Gabriela Menezes Gon çalves de Brito Enaldo Vieira de Melo Ant ônio Carlos Sobral Sousa Paulo Ricardo Martins-Filho Milena Dos Santos Barros Campos Source Type: research

A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil
Rev Inst Med Trop Sao Paulo. 2024 Feb 19;66:e12. doi: 10.1590/S1678-9946202466012. eCollection 2024.ABSTRACTWe conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result fo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Gerusa Figueiredo Francisco Chiaravalloti S érgio Campos Alessandra Cristina Guedes Pellini Alvina Clara Felix Expedito Luna Source Type: research

Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research

Cardiorespiratory optimal point in post-COVID-19 patients: a cross-sectional study
This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Karinne Sim ões da Cruz Santos Gabriela Menezes Gon çalves de Brito Enaldo Vieira de Melo Ant ônio Carlos Sobral Sousa Paulo Ricardo Martins-Filho Milena Dos Santos Barros Campos Source Type: research

A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil
Rev Inst Med Trop Sao Paulo. 2024 Feb 19;66:e12. doi: 10.1590/S1678-9946202466012. eCollection 2024.ABSTRACTWe conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result fo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Gerusa Figueiredo Francisco Chiaravalloti S érgio Campos Alessandra Cristina Guedes Pellini Alvina Clara Felix Expedito Luna Source Type: research

Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research

Cardiorespiratory optimal point in post-COVID-19 patients: a cross-sectional study
This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Karinne Sim ões da Cruz Santos Gabriela Menezes Gon çalves de Brito Enaldo Vieira de Melo Ant ônio Carlos Sobral Sousa Paulo Ricardo Martins-Filho Milena Dos Santos Barros Campos Source Type: research