Real-world effectiveness and safety of direct-acting antivirals for the treatment of hepatitis C virus in kidney and liver transplant recipients: experience of a large transplant center in Brazil
In conclusion, DAA treatment resulted in high rates of SVR and was well tolerated in both kidney and liver transplant patients. Adverse events were frequent but not severe in most patients, with low treatment drop-out rates. Interactions with immunosuppressants need monitoring since dose adjustments may be required. Reporting real-life experiences is important to help build evidence for patient management in non-controlled environments.PMID:38055377 | PMC:PMC10703500 | DOI:10.1590/S1678-9946202365059 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Larissa Sgaria Pacheco Pedro Enrico Ventura Roger Kist Valter Duro Garcia Gisele Meinerz Cristiane Valle Tovo Guido Pio Cracco Cantisani Maria Lucia Zanotelli Marcos Mucenic Elizete Keitel Source Type: research

Cutaneous Naganishia albida (Cryptococcus albidus) infection: a case report and literature review
We describe a case of an immunocompetent older male with cutaneous cryptococcosis caused by Naganishia albida following skin trauma, and conduct a literature review in PubMed, Lilacs, and Embase. Only six previous similar reports were found. The seven cases (including ours) were widely distributed geographically (Brazil, the US, the UK, Hungary, South Korea, and Iran), all males, and their ages varied, ranging from 14 to 86 years. Four individuals had underlying skin diseases (Sezary Syndrome, psoriasis, and skin rash without etiology) plus potentially immunosuppressive underlying conditions (diabetes mellitus, kidney tran...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: V ítor Falcão de Oliveira Alexandre Pereira Funari Mariane Taborda Adriana Satie Gon çalves Kono Magri Anna Sara Levin Marcello Mihailenko Chaves Magri Source Type: research

Multidrug-resistant tuberculous orchiepididymitis: a brief case report
Rev Inst Med Trop Sao Paulo. 2023 Dec 4;65:e61. doi: 10.1590/S1678-9946202365061. eCollection 2023.ABSTRACTTuberculosis (TB) is one of the leading causes of death by infectious diseases worldwide. Multidrug-resistant tuberculosis is a growing problem, especially in countries with high TB prevalence. Although the lungs are the organs most frequently affected by this disease, Mycobacterium tuberculosis can harm any organ, including the urogenital tract, causing extrapulmonary tuberculosis, which leads to a challenging diagnosis and consequent treatment delays. In this article, we present a case of orchiepididymitis caused by...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Jussemara Souza da Silva Ademir Silva Correia Denise Silva Rodrigues Source Type: research

Detection of Bartonella bovis DNA in blood samples from a veterinarian in Mexico
Rev Inst Med Trop Sao Paulo. 2023 Dec 4;65:e62. doi: 10.1590/S1678-9946202365062. eCollection 2023.ABSTRACTThe genus Bartonella encompasses 38 validated species of Gram-negative, facultative intracellular bacteria that colonize the endothelial cells and erythrocytes of a wide spectrum of mammals. To date, 12 Bartonella species have been recorded infecting humans, causing diseases of long historical characterization, such as cat scratch fever and trench fever, and emerging bartonellosis that mainly affect animal health professionals. For this reason, this study aimed to report a documented case of Bartonella bovis infecting...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Jannete Gamboa-Prieto Anabel Cruz-Romero Jos é A Jiménez-Hernández Jos é Rodrigo Ramos-Vázquez Gerardo G Ballados-Gonz ález Dora Romero-Salas Violeta T Pard ío-Sedas Sandra C Esparza-Gonzalez Ingeborg Becker Sokani S ánchez-Montes Source Type: research

Can COVID-19 impact the natural history of paracoccidioidomycosis? Insights from an atypical chronic form of the mycosis
Rev Inst Med Trop Sao Paulo. 2023 Dec 1;65:e57. doi: 10.1590/S1678-9946202365057. eCollection 2023.ABSTRACTParacoccidioidomycosis (PCM) is a systemic fungal infection caused by Paracoccidioides spp. It can occur as an acute/subacute form (A/SAF), a chronic form (CF) and rarely as a mixed form combining the features of the two aforementioned forms in an immunocompromised patient. Here, we report a 56-year-old male patient with CF-PCM who presented with atypical manifestations, including the development of an initial esophageal ulcer, followed by central nervous system (CNS) lesions and cervical and abdominal lymphatic invol...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Cesar Cilento Ponce Gisele Burlamaqui Klautau Nathan Costa Marques Wladimir Queiroz Rosely Antunes Patzina Gil Benard Jos é Angelo Lauletta Lindoso Source Type: research

Immune system gene polymorphisms associated with severe dengue in Latin America: a systematic review
The objective of this study was to perform a systematic review of the Latin American literature on these genes. An electronic literature search was carried out in PubMed, Scopus, Lilacs, and the Virtual Health Library, and reference lists of systematic reviews in the area. Case-control studies conducted in Latin American countries examining at least one form of genetic polymorphism related to immune responses against severe dengue were included. In total, 424 articles were identified and 26 were included in this systematic review. Of the 26 selected articles, 16 reported polymorphisms associated with the risk of developing...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Jorge Emilio Salazar Fl órez Ángela María Segura Cardona Berta Nelly Restrepo Jaramillo Margarita Arboleda Naranjo Luz Stella Giraldo Cardona Ángela Patricia Echeverri Rendón Source Type: research

Real-world effectiveness and safety of direct-acting antivirals for the treatment of hepatitis C virus in kidney and liver transplant recipients: experience of a large transplant center in Brazil
In conclusion, DAA treatment resulted in high rates of SVR and was well tolerated in both kidney and liver transplant patients. Adverse events were frequent but not severe in most patients, with low treatment drop-out rates. Interactions with immunosuppressants need monitoring since dose adjustments may be required. Reporting real-life experiences is important to help build evidence for patient management in non-controlled environments.PMID:38055377 | PMC:PMC10703500 | DOI:10.1590/S1678-9946202365059 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Larissa Sgaria Pacheco Pedro Enrico Ventura Roger Kist Valter Duro Garcia Gisele Meinerz Cristiane Valle Tovo Guido Pio Cracco Cantisani Maria Lucia Zanotelli Marcos Mucenic Elizete Keitel Source Type: research

Cutaneous Naganishia albida (Cryptococcus albidus) infection: a case report and literature review
We describe a case of an immunocompetent older male with cutaneous cryptococcosis caused by Naganishia albida following skin trauma, and conduct a literature review in PubMed, Lilacs, and Embase. Only six previous similar reports were found. The seven cases (including ours) were widely distributed geographically (Brazil, the US, the UK, Hungary, South Korea, and Iran), all males, and their ages varied, ranging from 14 to 86 years. Four individuals had underlying skin diseases (Sezary Syndrome, psoriasis, and skin rash without etiology) plus potentially immunosuppressive underlying conditions (diabetes mellitus, kidney tran...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: V ítor Falcão de Oliveira Alexandre Pereira Funari Mariane Taborda Adriana Satie Gon çalves Kono Magri Anna Sara Levin Marcello Mihailenko Chaves Magri Source Type: research

Multidrug-resistant tuberculous orchiepididymitis: a brief case report
Rev Inst Med Trop Sao Paulo. 2023 Dec 4;65:e61. doi: 10.1590/S1678-9946202365061. eCollection 2023.ABSTRACTTuberculosis (TB) is one of the leading causes of death by infectious diseases worldwide. Multidrug-resistant tuberculosis is a growing problem, especially in countries with high TB prevalence. Although the lungs are the organs most frequently affected by this disease, Mycobacterium tuberculosis can harm any organ, including the urogenital tract, causing extrapulmonary tuberculosis, which leads to a challenging diagnosis and consequent treatment delays. In this article, we present a case of orchiepididymitis caused by...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Jussemara Souza da Silva Ademir Silva Correia Denise Silva Rodrigues Source Type: research

Detection of Bartonella bovis DNA in blood samples from a veterinarian in Mexico
Rev Inst Med Trop Sao Paulo. 2023 Dec 4;65:e62. doi: 10.1590/S1678-9946202365062. eCollection 2023.ABSTRACTThe genus Bartonella encompasses 38 validated species of Gram-negative, facultative intracellular bacteria that colonize the endothelial cells and erythrocytes of a wide spectrum of mammals. To date, 12 Bartonella species have been recorded infecting humans, causing diseases of long historical characterization, such as cat scratch fever and trench fever, and emerging bartonellosis that mainly affect animal health professionals. For this reason, this study aimed to report a documented case of Bartonella bovis infecting...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Jannete Gamboa-Prieto Anabel Cruz-Romero Jos é A Jiménez-Hernández Jos é Rodrigo Ramos-Vázquez Gerardo G Ballados-Gonz ález Dora Romero-Salas Violeta T Pard ío-Sedas Sandra C Esparza-Gonzalez Ingeborg Becker Sokani S ánchez-Montes Source Type: research

Can COVID-19 impact the natural history of paracoccidioidomycosis? Insights from an atypical chronic form of the mycosis
Rev Inst Med Trop Sao Paulo. 2023 Dec 1;65:e57. doi: 10.1590/S1678-9946202365057. eCollection 2023.ABSTRACTParacoccidioidomycosis (PCM) is a systemic fungal infection caused by Paracoccidioides spp. It can occur as an acute/subacute form (A/SAF), a chronic form (CF) and rarely as a mixed form combining the features of the two aforementioned forms in an immunocompromised patient. Here, we report a 56-year-old male patient with CF-PCM who presented with atypical manifestations, including the development of an initial esophageal ulcer, followed by central nervous system (CNS) lesions and cervical and abdominal lymphatic invol...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Cesar Cilento Ponce Gisele Burlamaqui Klautau Nathan Costa Marques Wladimir Queiroz Rosely Antunes Patzina Gil Benard Jos é Angelo Lauletta Lindoso Source Type: research

Immune system gene polymorphisms associated with severe dengue in Latin America: a systematic review
The objective of this study was to perform a systematic review of the Latin American literature on these genes. An electronic literature search was carried out in PubMed, Scopus, Lilacs, and the Virtual Health Library, and reference lists of systematic reviews in the area. Case-control studies conducted in Latin American countries examining at least one form of genetic polymorphism related to immune responses against severe dengue were included. In total, 424 articles were identified and 26 were included in this systematic review. Of the 26 selected articles, 16 reported polymorphisms associated with the risk of developing...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Jorge Emilio Salazar Fl órez Ángela María Segura Cardona Berta Nelly Restrepo Jaramillo Margarita Arboleda Naranjo Luz Stella Giraldo Cardona Ángela Patricia Echeverri Rendón Source Type: research

Real-world effectiveness and safety of direct-acting antivirals for the treatment of hepatitis C virus in kidney and liver transplant recipients: experience of a large transplant center in Brazil
In conclusion, DAA treatment resulted in high rates of SVR and was well tolerated in both kidney and liver transplant patients. Adverse events were frequent but not severe in most patients, with low treatment drop-out rates. Interactions with immunosuppressants need monitoring since dose adjustments may be required. Reporting real-life experiences is important to help build evidence for patient management in non-controlled environments.PMID:38055377 | PMC:PMC10703500 | DOI:10.1590/S1678-9946202365059 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Larissa Sgaria Pacheco Pedro Enrico Ventura Roger Kist Valter Duro Garcia Gisele Meinerz Cristiane Valle Tovo Guido Pio Cracco Cantisani Maria Lucia Zanotelli Marcos Mucenic Elizete Keitel Source Type: research

Cutaneous Naganishia albida (Cryptococcus albidus) infection: a case report and literature review
We describe a case of an immunocompetent older male with cutaneous cryptococcosis caused by Naganishia albida following skin trauma, and conduct a literature review in PubMed, Lilacs, and Embase. Only six previous similar reports were found. The seven cases (including ours) were widely distributed geographically (Brazil, the US, the UK, Hungary, South Korea, and Iran), all males, and their ages varied, ranging from 14 to 86 years. Four individuals had underlying skin diseases (Sezary Syndrome, psoriasis, and skin rash without etiology) plus potentially immunosuppressive underlying conditions (diabetes mellitus, kidney tran...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: V ítor Falcão de Oliveira Alexandre Pereira Funari Mariane Taborda Adriana Satie Gon çalves Kono Magri Anna Sara Levin Marcello Mihailenko Chaves Magri Source Type: research

Multidrug-resistant tuberculous orchiepididymitis: a brief case report
Rev Inst Med Trop Sao Paulo. 2023 Dec 4;65:e61. doi: 10.1590/S1678-9946202365061. eCollection 2023.ABSTRACTTuberculosis (TB) is one of the leading causes of death by infectious diseases worldwide. Multidrug-resistant tuberculosis is a growing problem, especially in countries with high TB prevalence. Although the lungs are the organs most frequently affected by this disease, Mycobacterium tuberculosis can harm any organ, including the urogenital tract, causing extrapulmonary tuberculosis, which leads to a challenging diagnosis and consequent treatment delays. In this article, we present a case of orchiepididymitis caused by...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Jussemara Souza da Silva Ademir Silva Correia Denise Silva Rodrigues Source Type: research