Revista do Instituto de Medicina Tropical de Sao Paulo This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Incomplete recovery of the CD4+/CD8+ ratio is associated with the late introduction of antiretroviral therapy among people living with HIV infection
In conclusion, the increase in the CD4+/CD8+ ratio occurred mostly for patients undergoing early strategy treatment and its extension did not seem to be related to previous HIV-related factors.PMID:38324873 | PMC:PMC10846540 | DOI:10.1590/S1678-9946202466007 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 7, 2024 Category: Tropical Medicine Authors: Gabriela da Silva Prates Mariana Amelia Monteiro Éricka Constantinov Oliveira Najara Ataide de Lima Nascimento Ana Paula Rocha Veiga Mauricio Domingues Ferreira Thales Jos é Bueno Polis Gabriela Prandi Caetano Beatriz Rodrigues Pellegrina Soares Marcell Source Type: research

Identification of SARS-CoV-2 in urban rodents from Southern Mexico City at the beginning of the COVID-19 pandemic
This study aimed to molecularly identify the presence of SARS-CoV-2 in urban wild rodents from Mexico City, trapped along a water channel of a public park as part of a pest control program, at the beginning of the COVID-19 pandemic, during the fall and winter of 2020. Up to 33 Mus musculus and 52 R. norvegicus were captured and euthanized, large intestine samples with feces from the animals were obtained. RNAs were obtained and subjected to qRT-PCR for SARS-CoV-2 identification and threshold cycle (Ct) values were obtained. Four mice (12.1%) and three rats (5.8%) were positive, three rodents exhibited Ct<30. Our results...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 7, 2024 Category: Tropical Medicine Authors: Fernando Mart ínez-Hernández Nelly Raquel Gonzalez-Arenas Jos é Antonio Ocampo Cervantes Guiehdani Villalobos Angelica Olivo-Diaz Emilio Rendon-Franco Pablo Maravilla Mirza Romero Valdovinos Claudia Irais Mu ñoz-Garcia Source Type: research

The influence of growth time on the identification of Bartonella henselae strains by MALDI-TOF mass spectrometry
Rev Inst Med Trop Sao Paulo. 2024 Feb 5;66:e9. doi: 10.1590/S1678-9946202466009. eCollection 2024.ABSTRACTBartonella spp. are bacteria responsible for neglected diseases worldwide. Bartonella henselae is the species most associated with human infections. It is associated with a large spectrum of clinical manifestations and is potentially fatal. The identification of Bartonella spp. is considered a challenge in clinical routine. These bacteria are fastidious, and the time required to isolate them varies from one to six weeks. MALDI-TOF mass spectrometry has emerged as an application for research on Bartonella spp. , and has...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 7, 2024 Category: Tropical Medicine Authors: Karina de Almeida Lins Cristiane Santos Cruz Piveta Carlos Emilio Levy Marina Rovani Drummond Luciene Silva Dos Santos Alessandra Sussulini Paulo Eduardo Neves Ferreira Velho Source Type: research

Multiple myeloma and Chagas disease: qPCR as a marker for preemptive antiparasitic therapy: a case reports series and review
Rev Inst Med Trop Sao Paulo. 2024 Feb 5;66:e10. doi: 10.1590/S1678-9946202466010. eCollection 2024.ABSTRACTMultiple myeloma (MM) associated with Chagas disease is rarely described. This disease and its therapy suppress T cell and macrophage functions and increase regulatory T cell function, allowing the increase of parasitemia and the risk of Chagas Disease Reactivation (CDR). We aimed to analyze the role of conventional (cPCR) and quantitative Polymerase Chain Reaction (qPCR) for prospective monitoring of T. cruzi parasitemia, searching for markers of preemptive antiparasitic therapy in MM patients with Chagas disease. Mo...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 7, 2024 Category: Tropical Medicine Authors: Noemia Barbosa Carvalho Vera L úcia Teixeira de Freitas Fernanda Salles Seguro Rita Cristina Bezerra Giancarlo Fatobene Érika Yoshie Shimoda Nakanishi Helena Visnadi Gracia Martinez Marjorie Vieira Batista Vanderson Rocha Frederico Luis Dulley S ílvia Source Type: research

Prevalence and clinical consequences of Hepatitis C virus infection in patients undergoing hematopoietic stem cell transplantation
Rev Inst Med Trop Sao Paulo. 2024 Feb 5;66:e11. doi: 10.1590/S1678-9946202466011. eCollection 2024.ABSTRACTHepatitis C virus (HCV) infection is a significant cause of morbidity and mortality among hematopoietic stem cell transplant (HCT) recipients. In Brazil, its occurrence in HCT recipients remains undetermined. We now report on HCV prevalence in HCT recipients and its clinical consequences. The medical records of all HCT recipients seen at Hospital das Clinicas, Sao Paulo University Medical School, from January 2010 to January 2020 were reviewed to determine HCV serostatus. A retrospective analysis of medical charts was...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 7, 2024 Category: Tropical Medicine Authors: Ana Claudia Marques Barbosa Diaz Steven Sol Witkin Cesar de Almeida Neto Alfredo Mendrone Junior Vanderson Rocha Silvia Figueiredo Costa Jessica Fernandes Ramos Maria Cassia Mendes-Correa Source Type: research

Post-discharge all-cause mortality in COVID-19 recovered patients hospitalized in 2020: the impact of chronic kidney disease
In conclusion, a high six-month all-cause mortality was observed. Within the six-month follow-up, a higher risk of death was observed for patients who had prior CKD and longer hospital stay. These findings highlight the importance of more intensive medical surveillance during this period.PMID:38198374 | PMC:PMC10768652 | DOI:10.1590/S1678-9946202466001 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Authors: Guilherme Schittine Bezerra Lomba Pedro Henrique Abreu da Silva Natalia Fonseca do Ros ário Thalia Medeiros Lilian Santos Alves Andrea Alice Silva Jorge Reis Almeida Jocemir Ronaldo Lugon Source Type: research

Severe esophagitis induced by antituberculosis drugs: a case report
We present a case of a 56-year-old woman with diabetes who was diagnosed with Pulmonary Tuberculosis. After receiving antituberculosis drugs as part of her treatment, she experienced a range of systemic manifestations and suffered from severe ulcerative esophagitis. This adverse reaction led to uncontrollable gastrointestinal intolerance, tragically resulting in her untimely demise. The incident underscores the potential seriousness of adverse reactions that can arise from tuberculosis treatment medications.PMID:38198375 | PMC:PMC10768651 | DOI:10.1590/S1678-9946202466002 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Authors: Roxana Flores Mamani Franciele Moreira Silva Marcos Vidal de Lima-J únior Juliana Paitach de Oliveira Lima Vitor Montez Vianna Rivelino Trindade de Azevedo Billy McBenedict Ezequias Batista Martins Source Type: research

Prevalence and antimicrobial resistance profile of pathogens isolated from patients with urine tract infections admitted to a university hospital in a medium-sized Brazilian city
This study aimed to determine the antibiotic profile of microorganisms isolated from urine samples of patients with community urine tract infections (UTI) admitted to the University Hospital of the Federal University of Sao Carlos to support an appropriate local empirical treatment. A retrospective cross-sectional study was conducted from October 2018 to October 2020. Data from 1,528 positive urine cultures for bacterial pathogens and antibiograms were tabulated. Bacterial species prevalence and their resistance profile were analyzed and compared by sex and age. For Gram-negative fermenting bacteria, resistance rates were ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Authors: Mariana Negri B árbara Martins Lima Renata Dos Santos Batista Reis Woloszynek Roberto Augusto Silva Molina Carla Maria Ramos Germano D ébora Gusmão Melo Leandro C ândido de Souza Lucimar Retto da Silva de Av ó Source Type: research

The decline of measles antibody titers in previously vaccinated adults: a cross-sectional analysis
This study aimed to assess measles IgG antibody seropositivity and titers in previously vaccinated adults. A cross-sectional study was conducted at CRIE-HC-FMUSP (Sao Paulo, Brazil) in 2019. It included healthy adults who had received two or more Measles-Mumps-Rubella vaccines (MMR) and excluded individuals with immunocompromising conditions. Measles IgG antibodies were measured and compared by ELISA (Euroimmun®) and chemiluminescence (LIASON®). The association of seropositivity and titers with variables of interest (age, sex, profession, previous measles, number of measles-containing vaccine doses, interval between MMR ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Authors: Anna Carla Pinto Casti ñeiras Amanda Caroline Sales Camila de Melo Picone Const ância Lima Diogo Átila Duque Rossi Rafael Mello Galliez Orlando da Costa Ferreira Terezinha Marta Pereira Pinto Casti ñeiras Marta Helo ísa Lopes Ana Marli Christovam Sar Source Type: research

Evaluation of larval surface antigens from infective larvae of Strongyloides venezuelensis for the serodiagnosis of human strongyloidiasis
Rev Inst Med Trop Sao Paulo. 2024 Jan 5;66:e1err. doi: 10.1590/S1678-9946202466001err.ABSTRACT[This corrects the article doi: 10.1590/S1678-9946202365001].PMID:38198378 | PMC:PMC10768650 | DOI:10.1590/S1678-9946202466001err (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Source Type: research

Can COVID-19 impact the natural history of paracoccidioidomycosis? Insights from an atypical chronic form of the mycosis
Rev Inst Med Trop Sao Paulo. 2024 Jan 5;66:e57err. doi: 10.1590/S1678-9946202466057err.ABSTRACT[This corrects the article doi: 10.1590/S1678-9946202365057].PMID:38198379 | PMC:PMC10768649 | DOI:10.1590/S1678-9946202466057err (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - January 10, 2024 Category: Tropical Medicine Source Type: research

Can COVID-19 impact the natural history of paracoccidioidomycosis? Insights from an atypical chronic form of the mycosis
Rev Inst Med Trop Sao Paulo. 2023 Dec 1;65:e57. doi: 10.1590/S1678-9946202365057. eCollection 2023.ABSTRACTParacoccidioidomycosis (PCM) is a systemic fungal infection caused by Paracoccidioides spp. It can occur as an acute/subacute form (A/SAF), a chronic form (CF) and rarely as a mixed form combining the features of the two aforementioned forms in an immunocompromised patient. Here, we report a 56-year-old male patient with CF-PCM who presented with atypical manifestations, including the development of an initial esophageal ulcer, followed by central nervous system (CNS) lesions and cervical and abdominal lymphatic invol...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: C ésar Augusto Tomaz de Souza Cesar Cilento Ponce Gisele Burlamaqui Klautau Nathan Costa Marques Wladimir Queiroz Rosely Antunes Patzina Gil Benard Jos é Angelo Lauletta Lindoso Source Type: research

Immune system gene polymorphisms associated with severe dengue in Latin America: a systematic review
The objective of this study was to perform a systematic review of the Latin American literature on these genes. An electronic literature search was carried out in PubMed, Scopus, Lilacs, and the Virtual Health Library, and reference lists of systematic reviews in the area. Case-control studies conducted in Latin American countries examining at least one form of genetic polymorphism related to immune responses against severe dengue were included. In total, 424 articles were identified and 26 were included in this systematic review. Of the 26 selected articles, 16 reported polymorphisms associated with the risk of developing...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Jorge Emilio Salazar Fl órez Ángela María Segura Cardona Berta Nelly Restrepo Jaramillo Margarita Arboleda Naranjo Luz Stella Giraldo Cardona Ángela Patricia Echeverri Rendón Source Type: research

Real-world effectiveness and safety of direct-acting antivirals for the treatment of hepatitis C virus in kidney and liver transplant recipients: experience of a large transplant center in Brazil
In conclusion, DAA treatment resulted in high rates of SVR and was well tolerated in both kidney and liver transplant patients. Adverse events were frequent but not severe in most patients, with low treatment drop-out rates. Interactions with immunosuppressants need monitoring since dose adjustments may be required. Reporting real-life experiences is important to help build evidence for patient management in non-controlled environments.PMID:38055377 | PMC:PMC10703500 | DOI:10.1590/S1678-9946202365059 (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: Larissa Sgaria Pacheco Pedro Enrico Ventura Roger Kist Valter Duro Garcia Gisele Meinerz Cristiane Valle Tovo Guido Pio Cracco Cantisani Maria Lucia Zanotelli Marcos Mucenic Elizete Keitel Source Type: research

Cutaneous Naganishia albida (Cryptococcus albidus) infection: a case report and literature review
We describe a case of an immunocompetent older male with cutaneous cryptococcosis caused by Naganishia albida following skin trauma, and conduct a literature review in PubMed, Lilacs, and Embase. Only six previous similar reports were found. The seven cases (including ours) were widely distributed geographically (Brazil, the US, the UK, Hungary, South Korea, and Iran), all males, and their ages varied, ranging from 14 to 86 years. Four individuals had underlying skin diseases (Sezary Syndrome, psoriasis, and skin rash without etiology) plus potentially immunosuppressive underlying conditions (diabetes mellitus, kidney tran...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - December 6, 2023 Category: Tropical Medicine Authors: V ítor Falcão de Oliveira Alexandre Pereira Funari Mariane Taborda Adriana Satie Gon çalves Kono Magri Anna Sara Levin Marcello Mihailenko Chaves Magri Source Type: research