Asymptomatic Plasmodium infection in a residual malaria transmission area in the Atlantic Forest region: Implications for elimination
Abstract INTRODUCTION: Elimination of malaria in areas of interrupted transmission warrants careful case assessment to avoid the reintroduction of this disease. Occasional malaria cases are reported among visitors of the Atlantic Forest area of Brazil, while data on residents of this area are scarce. METHODS: A sectional study was carried out to examine 324 individuals living in a municipality where autochthonous cases were detected. RESULTS: Asymptomatic Plasmodium infections were detected in 2.8% of the individuals by polymerase chain reaction (PCR), with one case of P. falciparum (0.3%), two cases of P. vivax (0.6%), an...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 29, 2019 Category: Tropical Medicine Source Type: research

A randomized, open-label clinical trial comparing the long-term effects of miltefosine and meglumine antimoniate for mucosal leishmaniasis
CONCLUSIONS: Miltefosine may be an interesting alternative for treating ML because of its oral administration and cure rate after long-term follow-up. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 29, 2019 Category: Tropical Medicine Source Type: research

West Nile virus infections are here! Are we prepared to face another flavivirus epidemic?
Abstract Emerging arthropod-borne viruses (arboviruses), such as chikungunya and Zika viruses, are a major threat to public health in countries like Brazil where biodiversity is high and medical care is sometimes precarious. West Nile fever is a disease caused by the West Nile Virus (WNV), an RNA virus belonging to the Flaviviridae family. It is transmitted by infected mosquitoes to numerous animals like birds, reptiles and mammals, including human and non-human primates. In the last decade, the number of reported cases of WNV infection in humans and animals has increased in the Americas. Circulation of WNV in forests and ...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 29, 2019 Category: Tropical Medicine Source Type: research

Rheumatic heart disease in the modern era: recent developments and current challenges
Abstract Rheumatic heart disease (RHD) remains a major cause of preventable death and disability in children and young adults. Despite significant advances in medical technology and increased understanding of disease mechanisms, RHD continues to be a serious public health problem throughout the world, especially in low- and middle-income countries. Echocardiographic screening has played a key role in improving the accuracy of diagnosing RHD and has highlighted the disease burden. Most affected patients present with severe valve disease and limited access to life-saving cardiac surgery or percutaneous valve intervention, co...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 26, 2019 Category: Tropical Medicine Source Type: research

Challenging Management of Hepatitis B infection in Ankylosing Spondylitis Patients in an Endemic Area during Immunosuppressive Therapy
We report 3 cases of association between ankylosing spondylitis and hepatitis B with the use of immunosuppressant drugs. Case 1 was a patient with previous HBV infection using DMARD. Cases 2 and 3 were patients chronically infected by HBV during immunosuppressant therapy. The management of HBV infection during immunosuppressant therapy is challenging and needs multidisciplinary support. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

First report of Panstrongylus lignarius (Walker, 1873) (Hemiptera: Reduviidae: Triatominae) in the State of Acre, Brazil
CONCLUSIONS: The occurrence of P. lignarius deserves attention, since this species has the potential for domiciliation and transmitting Trypanosoma cruzi. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

Prevalence of HIV and associated factors among visceral leishmaniasis cases in an endemic area of Northeast Brazil
CONCLUSIONS The prevalence of VL-HIV co-infection was high and co-infected patients were more likely to have adverse outcomes. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

Extractivism of palm tree fruits: A risky activity because of snakebites in the state of Acre, Western Brazilian Amazon
CONCLUSIONS: During the harvesting of “ a çaí, ” there is the risk of the presence of B. atrox on the ground near the palm tree, and of B. bilineatus at the top of the palm tree. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

Quality of life of people with HIV/AIDS - the influence of social determinants and disease-related factors
CONCLUSIONS: Sociodemographic factors and HIV/AIDS-related aspects were influential in the QoL of people living with HIV/AIDS. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

Syphilis in female sex workers: an epidemiological study of the highway system of the state of Pará, northern Brazil
CONCLUSIONS: Several characteristics of FSWs were identified, which reinforce the need for measures guaranteeing their health and protection. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 18, 2019 Category: Tropical Medicine Source Type: research

Rheumatic heart disease in the modern era: recent developments and current challenges
Abstract Rheumatic heart disease (RHD) remains a major cause of preventable death and disability in children and young adults. Despite significant advances in medical technology and increased understanding of disease mechanisms, RHD continues to be a serious public health problem throughout the world, especially in low- and middle-income countries. Echocardiographic screening has played a key role in improving the accuracy of diagnosing RHD and has highlighted the disease burden. Most affected patients present with severe valve disease and limited access to life-saving cardiac surgery or percutaneous valve intervention, co...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

Francisco das Chagas Oliveira Luz (★1933 †2017)
We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the mother-fetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in p...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

Clinical Practice Guidelines for Chagas Disease: Recent Developments and Future Needs
We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the mother-fetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in p...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

Vaccination against influenza in elderly people: factors associated with acceptance and refusal of the vaccine
CONCLUSIONS: The vaccination coverage was below the national goal; the reasons for not being vaccinated was “ did not want to receive the vaccine ” , in addition to “ forgot ” . (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

The role of pregnant women with rash in the Zika virus sentinel surveillance
CONCLUSIONS Our results allowed the characterization of pregnant women exposed to ZIKV and the outcome of pregnancy. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

Rapid Detection of Sepsis using CESDA: the Caenorhabditis elegans Sepsis Detection Assay
Abstract INTRODUCTION The nematode Caenorhabditis elegans was used as a biological sensor to detect the urine of sepsis patients (CESDA assay). METHODS C. elegans was aliquoted onto the center of assay plates and allowed to migrate towards sepsis (T) or control (C) urine samples spotted on the same plate. The number of worms found in either (T) or (C) was scored at 10-minute intervals over a 60-minute period. RESULTS The worms were able to identify the urine (
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 15, 2019 Category: Tropical Medicine Source Type: research

Erratum: Hepatitis Delta Prevalence in South America: A Systematic Review and Meta-Analysis
We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the mother-fetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in p...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

IgG1 and IgG4 antibodies against Core and NS3 antigens of hepatitis C virus
Abstract INTRODUCTION: IgG subclasses involved in the immune response to hepatitis C virus (HCV) antigens have been rarely studied. We investigated the immune response mediated by IgG1 and IgG4 antibodies against the recombinant core and NS3 antigens in patients with chronic hepatitis C. METHODS: Sixty patients infected with HCV genotype 1 without antiviral treatment and 60 healthy subjects participated in the study. Serum levels of alanine aminotransferase, HCV viremia, and the presence of cryoglobulinemia and liver fibrosis were determined. We investigated the serum IgG1 and IgG4 antibodies against recombinant HCV core a...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Ecology of phlebotomine sand flies in an area of leishmaniasis occurrence in the Xakriabá Indigenous Reserve, Minas Gerais, Brazil
CONCLUSIONS: The results of the present study may contribute to a better understanding and targeting of the measures for preventing and controlling leishmaniasis by the authorities responsible for indigenous health. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

ERG11 gene polymorphisms and susceptibility to fluconazole in Candida isolates from diabetic and kidney transplant patients
CONCLUSIONS: Despite the high number of polymorphisms observed, the mutations occurred in regions that are not predicted to interfere with ergosterol synthesis, and therefore are not related to fluconazole resistance. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Superimposing a high-fat diet on Schistosoma mansoni infection affects renin-angiotensin system components in the mouse kidney
CONCLUSIONS: The finding regarding PRR is not yet clear. However, combining a high-fat diet and S. mansoni infection resulted in increased oxidative stress in the kidney that can aggravate hypertension as well as its associated complications. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Agreement between upper endoscopy and esophagography in the diagnosis of megaesophagus in Chagas disease
CONCLUSIONS Upper endoscopy has a high sensitivity, but a low specificity to diagnose megaesophagus. Agreement between the two exams varies depending on the megaesophagus grade. Thus, upper endoscopy can be used in the diagnostic workup of a possible Chagas disease megaesophagus, but all identified cases should undergo esophagography. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Current vector control challenges in the fight against malaria in Brazil
Abstract In Brazil, malaria is an important public health problem first reported in 1560. Historically, fluctuations in malaria cases in Brazil are attributed to waves of economic development; construction of railroads, highways, and hydroelectric dams; and population displacement and land occupation policies. Vector control measures have been widely used with an important role in reducing malaria cases. In this review article, we reviewed the vector control measures established in the Brazilian territory and aspects associated with such measures for malaria. Although some vector control measures are routinely used in Braz...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: A case report and literature review
We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the mother-fetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in p...
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Visceral leishmaniasis mimicking systemic lupus erythematosus
We present the first case of autochthonous VL mimicking SLE in Santa Catarina in southern Brazil. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

New record and extended geographical distribution of Aedes fluviatilis (Lutz, 1904) in Ceará, northeastern Brazil
CONCLUSIONS We report the first documentation of Ae. fluviatilis in the municipality of Saboeiro, northeastern Brazil. It is important to conduct additional entomological surveys to characterize the local Culicidae fauna. Ignoring the presence and dispersion of this vector could be a public health risk. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Reemerging diseases in Brazil: sociodemographic and epidemiological characteristics of syphilis and its under-reporting
CONCLUSIONS: The number of syphilis cases has varied over the years in the city. Incomplete compulsory reporting was noted. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene
CONCLUSIONS: Although the sample size is relatively small, these results suggest that P. falciparum artemisinin-resistant mutants do not exist in Brazil, thereby supporting the continuation of current treatment programs based on artemisinin-based combination therapy. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Circulation of spotted fever group rickettsiae among dogs seropositive for Leishmania spp. in an urban area of Brazil
CONCLUSIONS: This study shows low circulation of antibodies to R. rickettsii in CVL-seropositive dogs. It is recommended that surveillance studies in dogs should continue in order to monitor this scenario. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Use of Kisser glycerol gelatin to prepare microscope slides of Phlebotomine sandflies (Diptera: Psychodidae)
CONCLUSIONS: Use of Kisser glycerol gelatin is simple and efficient for preparing microscope slides of sandflies. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Congenital Chagas disease: alert of research negligence
CONCLUSIONS: Our data highlight the lack of research on congenital CD. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

TGF-β1 polymorphism in American tegumentary leishmaniasis in a Southern Brazilian population
CONCLUSIONS: G/G genotype of codon 25 in TGF- β 1 appeared to confer resistance, and G/C and C/C genotypes, susceptibility to TL in this population. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Association of serum levels of C-reactive protein with CRP-717 T/C polymorphism and viremia in HCV and HBV carriers
CONCLUSIONS: The present results demonstrated a close relationship between the ability of the virus to replicate and cause liver damage and low serum concentrations of C-reactive protein. Future research may determine if these results can be interpreted as a possible form of escape for the virus by decreasing its action as an opsonin and decreasing phagocytosis, which are functions of C-reactive protein in the immune response. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

Climatic variables associated with dengue incidence in a city of the Western Brazilian Amazon region
CONCLUSIONS: Considering the impact of global climate change on the region, these findings can help to predict trends in dengue fever incidence. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 21, 2019 Category: Tropical Medicine Source Type: research

The dentist’s role in syphilis prevention and control
Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium le...
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 14, 2019 Category: Tropical Medicine Source Type: research

Herpes simplex virus transmission following brown howler monkey (Alouatta guariba) bite
Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium le...
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 14, 2019 Category: Tropical Medicine Source Type: research

De novo histoid leprosy in a Colombian patient with multiple skin nodules on the ears and extremities
Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium le...
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 14, 2019 Category: Tropical Medicine Source Type: research

Temporal and spatial distribution of American tegumentary leishmaniasis in north Paraná: 2010-2015
CONCLUSIONS: American t egumentary leishmaniasis remains endemic and affects mostly men found in areas surrounded by woods; its treatment is partially efficient considering its side effects and incidence of recurrences. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 14, 2019 Category: Tropical Medicine Source Type: research

Stress conditions in the host induce persister cells and influence biofilm formation by Staphylococcus epidermidis RP62A
CONCLUSIONS: These findings highlight the role of host stress in the virulence of S. epidermidis. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - February 14, 2019 Category: Tropical Medicine Source Type: research

The use of meta-analysis in infectious disease surveillance: Is it a relevant tool?
CONCLUSIONS The inhibition of S. Typhimurium colonization by CCW is associated w ith the increase in TCD4+ and TCD8+ cells. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 31, 2019 Category: Tropical Medicine Source Type: research

β-Glucan of Candida albicans Cell Wall Extract Inhibits Salmonella Typhimurium Colonization by Potentiating Cellular Immunity (CD8 + and CD4 + T Cells)
CONCLUSIONS The inhibition of S. Typhimurium colonization by CCW is associated w ith the increase in TCD4+ and TCD8+ cells. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 31, 2019 Category: Tropical Medicine Source Type: research

Hansen’s disease deformities in a high risk area in Mozambique: A case study
CONCLUSIONS: High deformity rate is associated with low economic status, the belief that the disease is God ’ s desire, the use of traditional healers, late diagnosis, and poor disease management. A health education program targeting professionals and population, with infection screening and self-care groups can prevent deformities. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 31, 2019 Category: Tropical Medicine Source Type: research

Erratum: Prevalence and risk factors of toxoplasmosis among adults in a small Brazilian city
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 24, 2019 Category: Tropical Medicine Source Type: research

Luiz Fernando Ferreira (★1936 †2018)
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 24, 2019 Category: Tropical Medicine Source Type: research

Hepatitis Delta Prevalence in South America: A Systematic Review and Meta-Analysis
Abstract Hepatitis delta virus (HDV) has been associated with acute or chronic hepatitis in Latin America, but there is no prevalence study covering South American countries. This meta-analysis aimed to estimate anti-HDV prevalence through a systematic review of published articles in English, Portuguese and Spanish until December 2017. Searches were conducted in Health Virtual Library, Capes, Lilacs, PubMed, and SciELO, according to defined criteria regarding participant selection and geographical setting. Study quality was assessed using the GRADE guidelines. Pooled anti-HDV prevalence was calculated using the DerSimonian...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 24, 2019 Category: Tropical Medicine Source Type: research

Prevention of zoonotic diseases in immunocompromised patients: a neglected question
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 17, 2019 Category: Tropical Medicine Source Type: research

Venom concentrations in blisters and hemorrhagic bullae in a patient bitten by a Taiwan habu (Protobothrops mucrosquamatus)
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 17, 2019 Category: Tropical Medicine Source Type: research

Septic arthritis caused by Salmonella enterica serotype Rubislaw: A case report
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 17, 2019 Category: Tropical Medicine Source Type: research

Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 17, 2019 Category: Tropical Medicine Source Type: research

Biofilm formation by blood isolates of Candida parapsilosis sensu stricto in the presence of a hyperglycidic solution at comparable concentrations of total parenteral nutrition
CONCLUSIONS: Biofilm formation by C. parapsilosis sensu stricto in hyperglycidic medium may contribute to its pathogenic potential for fungemia related to TPN catheters. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - January 17, 2019 Category: Tropical Medicine Source Type: research