A Rare Case of Bilateral Tubal Ectopic Pregnancy Following Intracytoplasmic Sperm Injection-Embryo Transfer (ICSI-ET)
We report the case of bilateral tubal ectopic pregnancy. The patient was 30 years old and had a 3-year history of infertility; she was referred to the in-vitro fertilization (IVF) program because of tubal factor infertility. A pregnancy resulted from the transfer of two embryos during an artificial cycle. Despite the increase in β -hCG values during the follow-up, 22 days after the embryo transfer, the β -hCG levels were 2,408 U/L and the serum progesterone (P4) level was 10.53 ng/ml. After application with methotrexate, β -hCG levels did not decrease effectively. Moreover, the sonographic screening revealed a suspiciou...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Omega-3 Fatty Acids and Fecundation, Pregnancy and Breastfeeding
Abstract Long-chain omega-3 (n-3) polyunsaturated fatty acids (PUFAs), such as the eicosapentaenoic and docosahexaenoic acids, have been linked to human health in all stages of life, from fetal development to aging. These PUFAs act as precursors for various metabolites involved in the prevention of certain diseases. The recognizable effects of these supplements prior to pregnancy (oocyte maturation), during pregnancy (improvement in the risk of premature delivery, among others) and in the offspring (in terms of cognitive function and the approach to neurodevelopmental disorders) are described in the present narrative revie...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Junctional Zone in Infertile Women: A Three-dimensional Ultrasound Study
Conclusion The assessment of JZ visualization and continuity by 3D ultrasound is reproducible enough to be used in the clinical practice.Resumo Objetivo Analisar a reprodutibilidade inter e intraobservador da visualiza ção e continuidade da zona juncional (ZJ) por ecografia tridimensional (3D) em mulheres inférteis, e avaliar os fatores sociodemográficos, hormonais e estruturais que afetam essas avaliações. Métodos Um estudo prospectivo conduzido no Centro de Procriação Medicamente Assistida do Hospital Senhora da Oliveira, em Guimarães, Portugal. Foi realizada ecografia transvaginal 3D e gerados 2 volumes por...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Association between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population
Conclusion The present study suggests that the polymorphism in the intergenic region of chromosome 7 is associated with the risk of developing endometriosis in a population of Brazilian women from Juiz de Fora.Resumo Objetivo Investigar a associa ção de polimorfismos genéticos em genes candidatos ou regiões candidatas com o desenvolvimento da endometriose em mulheres brasileiras. Métodos Um total de 30 mulheres com diagnóstico de endometriose, com idade entre 25 e 64 anos, participaram da presente pesquisa, bem como 30 mulheres contro le, na mesma faixa etária, assintomáticas e sem história familiar da doença....
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Description of Referrals for Colposcopy in a Hospital in Brazil
Conclusion Most (60.16%) of the patients referred to the colposcopy service did not benefit from the referral for results without changes, such as negative colposcopies, histologies with no cervical intraepithelial neoplasm (CIN) or only CIN 1, or were out of the age for screening. These findings therefore demonstrate a significant number of unnecessary and inadequate referrals.Resumo Objetivo Descrever os encaminhamentos para colposcopia em um hospital no Brasil e a frequ ência relativa dos pacientes que foram beneficiados, considerando as indicações corretas para o exame e seus diagnósticos finais. Métodos Foi re...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

The Role of Ischemia-modified Albumin as a Biomarker in Preeclampsia
Conclusion The levels of serum IMA were higher in patients with preeclampsia than in healthy pregnancies. However, there was no significant correlation in terms of preeclampsia severity; more extensive, prospective and long-term studies are needed. (Source: Revista Brasileira de Ginecologia e Obstetricia)
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Use of Intensive Care Unit in Women with Severe Maternal Morbidity and Maternal Death: Results from a National Multicenter Study
Conclusion The current study indicates that the main variables associated with maternal death are the severity and adequacy of the case management, which is more frequent in ICU admissions. The use of the ICU without the stratification of the patients by severity may not produce the expected benefits for part of the women.Resumo Objetivo Avaliar o efeito da utiliza ção de unidades de terapia intensiva (UTIs) na mortalidade materna (MM) entre mulheres com morbidade materna grave (MMG). Materiais e Métodos Foi realizada uma análise secundária de um estudo transversal de vigilância de morbidade materna grave em 27 ce...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Health-related Behaviors in Pregnancy: A Key to Achieve Better Outcomes
(Source: Revista Brasileira de Ginecologia e Obstetricia)
Source: Revista Brasileira de Ginecologia e Obstetricia - April 22, 2020 Category: OBGYN Source Type: research

Metachronic Breast and Cerebellar Neoplasm in a Young Patient
Abstract Several factors trigger the development of genetic mutations that are responsible for causing a neoplasm. Medulloblastoma is a malignant and invasive cerebellar neoplasm, that affects children and young adults. Mucinous carcinoma is a special type of breast cancer. Being a special atypical subtype of invasive carcinoma, it most frequently affects women of advanced age and represents 1 to 7% of all breast cancers. The reported case aims to show the rarity of the occurrence of desmoplastic medulloblastoma and mammary mucinous carcinoma in a young patient in a short period of time, in different sites, without direct ...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Genital Injuries: Are They Telling us Something about Sexual Violence?
Abstract Genital injury has a forensic relevance after a sexual assault and it has been discussed and investigated among professionals who work in this field. To analyze the studies published in the last decades, the present review examines different factors that may influence this finding, first clarifying terms of the forensic field, such as the peculiarity of the legal medical examination, and the distinction of the terms “ legal ” and “ anatomical ” vagina. Finally, it analyses if it is possible that the existence of these injuries in victims explain the lack of consent in sexual contact, and to clarify the m...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Influence of Gender and Undergraduate Course on the Knowledge about HPV and HPV Vaccine, and Vaccination Rate among Students of a Public University
Conclusion As almost half of freshman women declared being sexually inactive, the investment in public health information programs and easier access to the HPV vaccine seem to be a useful strategy for undergraduate students.Resumo Objetivo Avaliar o conhecimento sobre a infec ção pelo vírus do papiloma humano (human papillomavirus, HPV, em inglês) e a taxa de vacinação entre estudantes calouros e veteranos do quarto ano dos cursos de medicina, farmácia, fonoaudiologia, enfermagem e educação física de uma universidade brasileira. Métodos Um primeiro questioná rio sobre aspectos sociodemográficos, antecedente...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Quality of Life in Women with Deep Endometriosis: A Cross-Sectional Study
Conclusion Although clinically treated, women with deep endometriosis present impairment in different domains of quality of life regardless of the questionnaire used for evaluation.Resumo Objetivo Descrever caracter ísticas clínicas e sociodemográficas de mulheres com endometriose profunda infiltrativa e avaliar sua qualidade de vida dentro de 6 meses de tratamento clínico. Métodos Estudo de corte transversal descritivo com 60 mulheres em seguimento ambulatorial na Universidade de Campinas, Campinas, SP, Brasil, com endometriose profunda infiltrativa diagnosticada por cirurgia ou métodos de imagem (ultrassonografi...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Increased Sympathetic Cardiac Autonomic Modulation after Two Consecutive Tilt Tests in Women with Polycystic Ovary Syndrome
Conclusion Women with PCOS had higher autonomic sympathetic cardiac modulation even after a second tilt test. No adaptation to this provocative test was observed. Spectral analysis was more sensitive for identifying differences between groups than the symbolic analysis.Resumo Objetivo O presente estudo teve como objetivo analisar a modula ção autonômica cardíaca por análise espectral e simbólica da variabilidade da frequência cardíaca (VFC) em mulheres com síndrome dos ovários policísticos (SOP) que foram submetidas a dois testes consecutivos de inclinação. Métodos Um total de 64 mulheres foram selecionada...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Gestational Outcomes in Patients with Severe Maternal Morbidity Caused by Hypertensive Syndromes
Conclusion In the severe morbidity/maternal near miss population, the presence of hypertensive complications was prevalent, constituting a risk factor for both the mother and the fetus.Resumo Objetivo Avaliar o impacto da presen ça de critérios de morbidade materna grave e potencial evento adverso materno associados a distúrbios hipertensivos nos desfechos maternos e perinatais em uma maternidade escola. Métodos Trata-se de uma subanálise de um estudo maior, envolvendo 27 centros, que estimou a prevalência de morbida de materna grave e potencial evento adverso no Brasil. Realizou-se um estudo analítico e transver...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research

Factors Associated with Inadequate Birth Intervals in the BRISA Birth Cohort, Brazil
Conclusion Older mothers were more likely to have long birth intervals, and higher parity increases the chances of short birth intervals. Furthermore, gestational diabetes and adequate prenatal care presented higher chances of having adequate birth intervals, indicating that health assistance during pregnancy is important to encourage an adequate interval between gestations.Resumo Objetivo Determinar a preval ência de intervalo inadequado de nascimento e seus fatores associados no estudo BRISA. Métodos Estudo transversal com dados da coorte BRISA. O intervalo de nascimento foi categorizado em “ adequado ” ( ≥ ...
Source: Revista Brasileira de Ginecologia e Obstetricia - April 17, 2020 Category: OBGYN Source Type: research