An emerging novel virus: Atypical porcine pestivirus (APPV)
This article focuses on the recently emerging atypical porcine pestivirus (APPV) that potentially threatens global swine herd health security. The virus was first identified in 2016, in the United States and thereafter, accumulated evidence shows that it is currently distributed in three continents. The clinical presentation of APPV ‐infected pigs is characterized by congenital tremor (CT) type A‐II in piglets, while adult pigs may become persistent carriers and shedders. Here, a literature review is conducted to summarize the published findings in the virus genomic biology, transmission, epidemiology, pathogenesis, an...
Source: Reviews in Medical Virology - November 9, 2018 Category: Virology Authors: Shuonan Pan, Chunxiao Mou, Zhenhai Chen Tags: REVIEW Source Type: research

Virus detection by transmission electron microscopy: Still useful for diagnosis and a plus for biosafety
SummaryTransmission electron microscopy (TEM) is the only imaging technique allowing the direct visualization of viruses, due to its nanometer ‐scale resolution. Between the 1960s and 1990s, TEM contributed to the discovery of many types of viruses and served as a diagnostic tool for identifying viruses directly in biological samples, either in suspension or in sections of tissues or mammalian cells grown in vitro in contact with clinica l samples. The diagnosis of viral infections improved considerably during the 1990s, with the advent of highly sensitive techniques, such as enzyme‐linked immunosorbent assay (ELISA) a...
Source: Reviews in Medical Virology - November 9, 2018 Category: Virology Authors: Philippe Roingeard, Pierre ‐Ivan Raynal, Sébastien Eymieux, Emmanuelle Blanchard Tags: REVIEW Source Type: research

Influenza vaccine: Where are we and where do we go?
SummaryThe alarming rise of morbidity and mortality caused by influenza pandemics and epidemics has drawn attention worldwide since the last few decades. This life ‐threatening problem necessitates the development of a safe and effective vaccine to protect against incoming pandemics. The currently available flu vaccines rely on inactivated viral particles, M2e‐based vaccine, live attenuated influenza vaccine (LAIV) and virus like particle (VLP). While inac tivated vaccines can only induce systemic humoral responses, LAIV and VLP vaccines stimulate both humoral and cellular immune responses. Yet, these vaccines have lim...
Source: Reviews in Medical Virology - November 8, 2018 Category: Virology Authors: Mohsen Keshavarz, Hamed Mirzaei, Maryam Salemi, Fatemeh Momeni, Mohammad Javad Mousavi, Mona Sadeghalvad, Yaser Arjeini, Farid Solaymani ‐Mohammadi, Javid Sadri Nahand, Haideh Namdari, Talat Mokhtari‐Azad, Farhad Rezaei Tags: REVIEW Source Type: research

An update on enterovirus 71 infection and interferon type I response
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 31, 2018 Category: Virology Authors: Mojtaba Rasti, Hashem Khanbabaei, Ali Teimoori Source Type: research

Orf virus: A promising new therapeutic agent
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 29, 2018 Category: Virology Authors: Ruixue Wang, Yong Wang, Fang Liu, Shuhong Luo Source Type: research

Going beyond serology for stratifying the risk of CMV infection in transplant recipients
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 25, 2018 Category: Virology Authors: David Navarro, Mario Fern ández‐Ruiz, José María Aguado, Virginia Sandonís, Pilar Pérez‐Romero Source Type: research

Reply to Simon et al. on “The neurological complications of chikungunya virus: A systematic review”
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 24, 2018 Category: Virology Authors: Ravi Mehta, Patrick Gerardin, Carlos Alexandre Antunes Brito, Cristiane Nascimento Soares, Maria Lucia Brito Ferreira, Tom Solomon Source Type: research

Viral disease of the year: Anterior uveitis
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 24, 2018 Category: Virology Authors: Paul D. Griffiths Source Type: research

Cytomegalovirus infection in day care centres: A systematic review and meta ‐analysis of prevalence of infection in children
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - October 11, 2018 Category: Virology Authors: Qing Yu Zheng, Kim T. Huynh, Wendy J. Zuylen, Maria E. Craig, William D. Rawlinson Source Type: research

Harnessing CRISPR/Cas 9 System for manipulation of DNA virus genome
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - September 27, 2018 Category: Virology Authors: Saeedeh Ebrahimi, Ali Teimoori, Hashem Khanbabaei, Maryam Tabasi Source Type: research

Emerging trends of Nipah virus: A review
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - September 25, 2018 Category: Virology Authors: Vikrant Sharma, Sulochana Kaushik, Ramesh Kumar, Jaya Parkash Yadav, Samander Kaushik Source Type: research

Defects in interferon pathways as potential biomarkers of sensitivity to oncolytic viruses
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - September 13, 2018 Category: Virology Authors: Olga V.Matveeva , Peter M.Chumakov Source Type: research

Issue Information
Reviews in Medical Virology,Volume 28, Issue 5, September 2018. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - September 7, 2018 Category: Virology Source Type: research

Immune function of plasmacytoid dendritic cells, natural killer cells, and their crosstalk in HBV infection
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - September 3, 2018 Category: Virology Authors: ForoughGolsaz ‐Shirazi , Mohammad MehdiAmiri , FazelShokri Source Type: research

Rotavirus: Genetics, pathogenesis and vaccine advances
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 29, 2018 Category: Virology Authors: AsmaSadiq , NazishBostan , Kwe ClaudeYinda , SaadiaNaseem , SadiaSattar Source Type: research

Simplified approach to uncertainty of measurement in the clinical virology laboratory
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 16, 2018 Category: Virology Authors: HowardNewman , VhudzaniTshisevhe Source Type: research

Dengue hemophagocytic syndrome: A systematic review and meta ‐analysis on epidemiology, clinical signs, outcomes, and risk factors
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 15, 2018 Category: Virology Authors: Hoang Thi NamGiang , KeitaBanno , Le Huu NhatMinh , Lam TuyetTrinh , Le ThaiLoc , AsmaaEltobgy , Luu Lam ThangTai , AdnanKhan , Nguyen HoangTuan , YaserReda , MaryanSamsom , Nguyen TranNam , Nguyen TienHuy , KenjiHi Source Type: research

Systematic review of the impact of point ‐of‐care testing for influenza on the outcomes of patients with acute respiratory tract infection
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 13, 2018 Category: Virology Authors: EceEgilmezer , Gregory J.Walker , PadmavathyBakthavathsalam , Joshua R.Peterson , J. JustinGooding , WilliamRawlinson , SachaStelzer ‐Braid Source Type: research

“Therapeutic applications of the ‘NPGP’ family of viral 2As”
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 10, 2018 Category: Virology Authors: Garry A.Luke , Martin D.Ryan Source Type: research

Zooepidemic: Thinking about the HIV pandemic, 40  years on
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 8, 2018 Category: Virology Authors: Philip P.Mortimer Source Type: research

Untold stories of the Zika virus epidemic in Brazil
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 3, 2018 Category: Virology Authors: Vivian I.Avelino ‐Silva , Esper G.Kallas Source Type: research

The wide spectrum of neurological consequences of chikungunya disease
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 3, 2018 Category: Virology Authors: FabriceSimon , Jos é‐LuisBarnay , AnnieLannuzel Source Type: research

Untold stories of the Zika virus epidemic in Brazil
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 3, 2018 Category: Virology Authors: Vivian I.Avelino ‐Silva , Esper G.Kallas Source Type: research

The wide spectrum of neurological consequences of chikungunya disease
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 3, 2018 Category: Virology Authors: FabriceSimon , Jos é‐LuisBarnay , AnnieLannuzel Source Type: research

Molecular epidemiology and phylogenetics of human enteroviruses: Is there a forest behind the trees?
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - August 2, 2018 Category: Virology Authors: Alexander N.Lukashev , Yulia A.Vakulenko , Natalia A.Turbabina , Andrei A.Deviatkin , Jan FelixDrexler Source Type: research

Can we distinguish respiratory viral infections based on clinical features? A prospective pediatric cohort compared to systematic literature review
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 25, 2018 Category: Virology Authors: XiaolinMa , TimConrad , MarenAlchikh , JanineReiche , BrunhildeSchweiger , BarbaraRath Source Type: research

Contribution of herpesviruses in the progression of periodontal and peri ‐implant diseases in systemically healthy individuals
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 19, 2018 Category: Virology Authors: MunerahBinshabaib , Shatha SubhiALHarthi , DanialSalehpoor , DimitriosMichelogiannakis , FawadJaved Source Type: research

Developmental progress of CRISPR/Cas9 and its therapeutic applications for HIV ‐1 infection
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 19, 2018 Category: Virology Authors: QiudiDeng , ZishengChen , LeiShi , HuafengLin Source Type: research

Contribution of herpesviruses in the progression of periodontal and peri ‐implant diseases in systemically healthy individuals
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 19, 2018 Category: Virology Authors: MunerahBinshabaib , Shatha SubhiALHarthi , DanialSalehpoor , DimitriosMichelogiannakis , FawadJaved Source Type: research

Developmental progress of CRISPR/Cas9 and its therapeutic applications for HIV ‐1 infection
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 19, 2018 Category: Virology Authors: QiudiDeng , ZishengChen , LeiShi , HuafengLin Source Type: research

Issue Information
Reviews in Medical Virology,Volume 28, Issue 4, July 2018. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - July 11, 2018 Category: Virology Source Type: research

Deregulation of the Notch pathway as a common road in viral carcinogenesis
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - June 29, 2018 Category: Virology Authors: Elena éVázquez‐Ulloa , MarcelaLizano , MarikaSjöqvist , LeslieOlmedo‐Nieva , AdrianaContreras‐Paredes Source Type: research

Diversity of hepatitis E virus genotype 3
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - June 25, 2018 Category: Virology Authors: FlorenceNicot , NicolasJeanne , AlainRoulet , CarolineLefebvre , RomainCarcenac , MaximeManno , MartineDubois , NassimKamar , S ébastienLhomme , FlorenceAbravanel , JacquesIzopet Source Type: research

Cytomegalovirus vaccine: timing is important
Reviews in Medical Virology,Volume 28, Issue 4, July 2018. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - June 19, 2018 Category: Virology Authors: P.D.Griffiths Source Type: research

Cytomegalovirus vaccine: timing is important
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - June 19, 2018 Category: Virology Authors: P.D.Griffiths Source Type: research

Congenital Zika syndrome: Pitfalls in the placental barrier
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - May 15, 2018 Category: Virology Authors: NiaRobinson , Evangelina E.Mayorquin Galvan , Isidro G.Zavala Trujillo , Maria G.Zavala ‐Cerna Source Type: research

Hepatitis B virus (HBV) reactivation —The potential role of direct‐acting agents for hepatitis C virus (HCV)
Reviews in Medical Virology,Volume 28, Issue 4, July 2018. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - May 15, 2018 Category: Virology Authors: Jason T.Blackard , Kenneth E.Sherman Source Type: research

Congenital Zika syndrome: Pitfalls in the placental barrier
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - May 15, 2018 Category: Virology Authors: NiaRobinson , Evangelina E.Mayorquin Galvan , Isidro G.Zavala Trujillo , Maria G.Zavala ‐Cerna Source Type: research

Hepatitis B virus (HBV) reactivation —The potential role of direct‐acting agents for hepatitis C virus (HCV)
Reviews in Medical Virology, EarlyView. (Source: Reviews in Medical Virology)
Source: Reviews in Medical Virology - May 15, 2018 Category: Virology Authors: Jason T.Blackard , Kenneth E.Sherman Source Type: research