Anemia and eosinophilia secondary to Strongyloides in a patient treated with anti-TNF-alpha
Publication date: Available online 23 December 2019Source: Reumatología Clínica (English Edition)Author(s): Águeda Prior-Español, Silvia Roure, Lourdes Mateo, Melania Martínez-Morillo (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - December 24, 2019 Category: Rheumatology Source Type: research
IgG4-related disease: Is rituximab the best therapeutic strategy for cases refractory to conventional therapy? Results of a systematic review
ConclusionThe use of rituximab for patients refractory to first-line treatments was associated with a high response percentage and less dependence on glucocorticoids.ResumenIntroducciónLa enfermedad relacionada con IgG4 es una condición fibroinflamatoria caracterizada por infiltración linfoplasmocítica con predominio de células plasmáticas IgG4+, fibrosis y en la mayoría de los casos niveles séricos elevados de IgG4. Puede afectar cualquier órgano y llevar a manifestaciones clínicas variables. El tratamiento con esteroides es la piedra angular, sin embargo, el porcentaje de recidivas es alto. Estudios recientes h...
Source: Reumatologia Clinica - December 24, 2019 Category: Rheumatology Source Type: research
Diagnostic value of anti-fibrinogen citrullinated peptide in rheumatoid arthritis
ConclusionsThe immunoassay designed with a citrullinated fibrinogen peptide has a high diagnostic value and can identify patients with greater clinical activity in early rheumatoid arthritis.ResumenObjetivoDeterminar el valor diagnóstico de los anticuerpos contra un péptido del fibrinógeno citrulinado, en pacientes cubanos con artritis reumatoide (AR), mediante un inmunoanálisis enzimático.Materiales y métodosSe sintetizó un péptido del fibrinógeno citrulinado diseñado por predicción informática y se utilizó en un inmunoanálisis enzimático. Participaron 81 pacientes con AR temprana, 81 pacientes con AR estab...
Source: Reumatologia Clinica - December 19, 2019 Category: Rheumatology Source Type: research
Relevance of a normal ultrasound study in patients with non-traumatic acute shoulder pain
Publication date: Available online 17 December 2019Source: Reumatología Clínica (English Edition)Author(s): Carlos Antonio Guillen Astete, Veronica Garcia Garcia, Monica Luque Alarcon (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - December 18, 2019 Category: Rheumatology Source Type: research
Association between overweight/obesity and clinical activity in rheumatoid arthritis
ConclusionsPrevalence of obesity in RA varies according to BMI cut-off points. Overweight and obesity were associated with higher inflammatory activity characterised by a higher count of tender and swollen joints. A positive correlation was found between swollen joint amount and the majority of the body fat mass indicators assessed. Body composition assessment/improvement should be an important part of the routine care of RA patients.ResumenIntroducciónLa asociación entre la presencia de sobrepeso/obesidad y el estado clínico de la artritis reumatoide (AR) es un tema aún no resuelto.ObjetivoEvaluar la asociación entre...
Source: Reumatologia Clinica - December 18, 2019 Category: Rheumatology Source Type: research
Frequency of positive ANCA test in a population with clinical symptoms suggestive of autoimmune disease and the interference of ANA in its interpretation
ConclusionsThe results suggest an overestimated request for ANCAs as a diagnostic aid in primary care which was not addressed. For an adequate evaluation of ANCAs, the indirect immunofluorescence technique should be implemented for the control and confirmation with the determination of specific antigens for anti-proteinase 3 and anti-myeloperoxidase in any of the confirmatory assays. The high concordance shown by ANCA CytoBeads makes us consider the use of this alternative for the determination of ANCAs and the confirmation. Given the interference of ANAs, the ANA test by IFI in the presence of positive P-ANCA results is r...
Source: Reumatologia Clinica - December 10, 2019 Category: Rheumatology Source Type: research
Arthralgias and articular hyperlaxitude in women with ophthalmopathy and early deafness
Publication date: Available online 9 December 2019Source: Reumatología Clínica (English Edition)Author(s): Francisco Gallo Puelles, Ana Teresa Serrano Anton, Vanesa Lopez Gonzalez, Jose Hurtado Martinez (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - December 9, 2019 Category: Rheumatology Source Type: research
Survey of satisfaction of biological treatments in a regional hospital
Publication date: Available online 9 December 2019Source: Reumatología Clínica (English Edition)Author(s): Dolors Grados, Marta Cucurell, Fina Bové, Alexandra Retamero (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - December 9, 2019 Category: Rheumatology Source Type: research
Chronic anterior uveitis in a patient with CREST syndrome
We present the case of a 53-year-old woman with CREST syndrome and chronic anterior uveitis, which we consider of clinical relevance given its low prevalence.ResumenLa esclerosis sistémica es una conectivopatía con unas manifestaciones clínicas muy heterogéneas, relacionándose en un pequeño porcentaje con enfermedades oculares inflamatorias. En el caso concreto de las uveítis, únicamente se han descrito casos aislados en la literatura, sobre todo con relación al síndrome de CREST. Presentamos el caso de una mujer de 53 años, con síndrome de CREST y uveítis anterior crónica, que consideramos de relevancia clí...
Source: Reumatologia Clinica - December 8, 2019 Category: Rheumatology Source Type: research
Recommendations of the Spanish Rheumatology Society for primary antiphospholipid syndrome. Part I: Diagnosis, evaluation and treatment
ConclusionsAn update of the SER recommendations on APS is presented. This document corresponds to part I, related to diagnosis, evaluation and treatment. These recommendations are considered tools for decision-making for clinicians, taking into consideration both the decision of the physician experienced in APS and the patient. A part II has also been prepared, which addresses aspects related to obstetric SAF and special situations.ResumenObjetivoLa dificultad para el diagnóstico y la variedad de manifestaciones clínicas que pueden determinar la elección del tratamiento del síndrome antifosfolípido (SAF) primario ha i...
Source: Reumatologia Clinica - December 8, 2019 Category: Rheumatology Source Type: research
Radioisotope synoviorthesis in the control of refractory synovitis in Castilla-La Mancha. A 10-year experience
Discussion and conclusionsIn patients with episodes of recurrent arthritis with associated joint effusion in one or two joints, refractory to systemic treatments, to local infiltrations with corticosteroids and for patients for whom other treatments may be contraindicated, we must consider the possibility of performing an isotope radiosinoviortesis, as it is a simple, safe technique with a success rate of more than 50%.ResumenNuestro hospital es el hospital de referencia en medicina nuclear para la realización de la sinoviortesis radioisotópica para toda Castilla La-Mancha.ObjetivoDescribir la experiencia en la realizaci...
Source: Reumatologia Clinica - December 8, 2019 Category: Rheumatology Source Type: research
Recommendations of the Spanish Rheumatology Society for primary antiphospholipid syndrome. Part II: Obstetric antiphospholipid syndrome and special situations
ConclusionsUpdate of SER recommendations on APS is presented. This document corresponds to part II, related to obstetric SAF and special situations. These recommendations are considered tools for decision-making for clinicians, taking into consideration both the decision of the physician experienced in APS and the patient. A Part I has also been prepared, which addresses aspects related to diagnosis, evaluation and treatment.ResumenObjetivoLa dificultad para el diagnóstico y la variedad de manifestaciones clínicas que pueden determinar la elección del tratamiento del síndrome antifosfolípido (SAF) primario ha impulsad...
Source: Reumatologia Clinica - December 8, 2019 Category: Rheumatology Source Type: research
Mucosal anti-infections vaccines: Beyond conventional vaccines
Publication date: Available online 2 December 2019Source: Reumatología Clínica (English Edition)Author(s): Silvia Sánchez Ramón, Mario Manzanares, Gloria CandelasAbstractAn urgent search is currently underway for alternatives to antibiotics to prevent infections, due to the accelerated evolution and increase in antibiotic resistance. This problem is more serious for patients with recurrent infections, since they have to use many cycles of antibiotics per year, so the risk for antibiotic resistance is higher and can be life-threatening. In recent years, the use of prophylactic vaccines via the mucosal route for these pa...
Source: Reumatologia Clinica - December 3, 2019 Category: Rheumatology Source Type: research
Response to: A comparative study of doppler ultrasound against temporal artery biopsy in the diagnosis of giant cell arteritis
Publication date: Available online 29 November 2019Source: Reumatología Clínica (English Edition)Author(s): Eugenio de Miguel, Irene Monjo (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - November 30, 2019 Category: Rheumatology Source Type: research
Ultrasound evaluation in gouty patients with persistent clinical activity despite uricaemia within the objective required by “treat to target”
Publication date: Available online 29 November 2019Source: Reumatología Clínica (English Edition)Author(s): Marta Novella Navarro, Enrique Calvo Aranda, José Luis Cabrera Alarcón, Paloma García de la Peña Lefebvre (Source: Reumatologia Clinica)
Source: Reumatologia Clinica - November 29, 2019 Category: Rheumatology Source Type: research
