Massive retinal neovascularization in von hippel–lindau disease: anti–vascular endothelial growth factor, vitrectomy, immunohistochemistry, and optical coherence tomography features
Conclusion: Ocular von Hippel–Lindau disease may be associated with RNV and macular traction. In such cases, RNV is likely responsive to anti–vascular endothelial growth factor and may be removed surgically along a cleavage plane between the tissue proliferation and the inner retina. In the reported case, the procedure was found to be safe and associated with macular anatomical improvement and vision recovery. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Intermediate uveitis with retinal detachment in a patient with pompe disease
Conclusion: Enzyme replacement therapy has improved the survival of individuals with Pompe disease. With greater patient longevity, new ocular associations may continue to emerge. Whether intermediate uveitis is an ocular association of Pompe disease remains to be determined. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Vitrectomy for stellate nonhereditary idiopathic foveomacular retinoschisis associated with outer retinal layer defect
Conclusion: Stellate nonhereditary idiopathic foveomacular retinoschisis may be associated with outer retinal layer defect and severe vision loss. Pars plana vitrectomy with internal limiting membrane removal and C3F8 infusion seems to be a safe and feasible treatment in such cases, with potentially good anatomical and functional outcome. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Bilateral paracentral acute middle maculopathy after cardiopulmonary bypass
Conclusion: Although symptomatic postoperative vision loss is a rare complication of cardiac surgery, intraoperative retinal microvascular nonperfusion as a consequence of extracorporeal circulation of blood may be a more common and under-recognized occurrence. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Autofluorescent timeline of spots and dots in multiple evanescent white dot syndrome
Conclusion: This case report illustrates the different recovery timelines of spots and dots in multiple evanescent white dot syndrome. Although both lesion types are hyperautofluorescent, the mechanism of autofluorescence is distinctive and may be explained by their contrasting pathoanatomy. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Retinal pigment epithelial irregularity and atrophy after internal membrane peeling: a report of two cases
Conclusion: In uncomplicated vitrectomy consisting of brilliant blue-green–assisted internal limiting membrane peeling, a remote risk of widespread retinal pigment epithelial damage exists even with the use of modern endoilluminators and relatively short surgical duration. Retinal phototoxicity seems to be the primary cause; however, dye-related cytotoxicity or a combination of both cannot be ruled out. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Brief Report Source Type: research

Ocular manifestations of poretti-boltshauser syndrome: findings from multimodal imaging and electrophysiology
Conclusion: Patients with Poretti-Boltshauser syndrome may possess chorioretinal thinning and retinal vascular abnormalities appreciable on examination and multimodal imaging. These findings suggest a role for LAMA1 in retinal and choroidal vascular development. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Topographic optical coherence tomography segmentation shows limited ellipsoid zone recovery in mild hydroxychloroquine retinopathy
Conclusion: Anatomic EZ recovery, when present, was restricted to regions of mild damage and did not correlate with fundus autofluorescence or improvement in visual fields. Topographic mapping seemed no more sensitive locally than cross-sectional OCT but may aid detection and longitudinal follow-up of toxicity by showing early damage or changes in the macula that could be missed with individual cross-sections. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Brief Report Source Type: research

Ctnnb1 (β-catenin) vitreoretinopathy: imaging characteristics and surgical management
Conclusion: CTNNB1 mutations can cause a vision-threatening vitreoretinopathy. We recommend CTNNB1 to be considered as part of the workup of patients presenting with familial exudative vitreoretinopathy–like clinical findings, especially if there are systemic manifestations. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - May 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Optical coherence tomography and optical coherence tomography angiography findings and visual prognosis in two patients with posterior microphthalmos
Conclusion: Unique OCT angiography findings in posterior microphthalmos are described herein. These findings may support the diagnosis of posterior microphthalmos and aid in the understanding of the pathogenesis of this disease. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Ipsilateral bullous exudative retinal detachment associated with extracorporeal membrane oxygenation
Conclusion: Extracorporeal membrane oxygenation may be associated with bullous exudative retinal detachment in rare cases where there is a possible anatomical or physiological predisposition. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Chorioretinal folds in patients with central serous chorioretinopathy
Conclusion: Although possibly coincidental, the presence of chorioretinal folds in hyperopic central serous chorioretinopathy eyes could be due to the excessive thickness of the choroid in eyes with hyperopia related to short axial length. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Late recurrence of choroidal neovascularization in patients with multifocal choroiditis: clinical surveillance in perpetuity
Conclusion: Patients with MFC are never exempt from recurrent CNV, warranting follow-up in perpetuity. Age-related factors are important to consider which may increase the susceptibility for activating MFC-associated CNV in elderly people. Macular neovascularization could respond to a standard approach to management, in these patients with MFC, by a judicious use of intravitreal injections of anti–vascular endothelial growth factor therapy. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Brief Report Source Type: research

SELF-INFLICTED LASER-INDUCED MACULOPATHY MASQUERADING AS POSTERIOR UVEITIS IN A PATIENT WITH SUSPECTED IgG4-RELATED DISEASE
Conclusion: Pattern recognition is important in establishing a diagnosis of self-inflicted handheld laser-induced maculopathy which can masquerade as posterior uveitis. Increasing availability of powerful Class IIIb laser devices in both developed and developing countries will likely increase the incidence of this entity. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Optical coherence tomography angiography imaging of choroidal neovascularization secondary to choroidal rupture treated by intravitreal ranibizumab
Conclusion: Optical coherence tomography angiography is able to detect choroidal neovascularization secondary to CR at baseline and during the follow-up after a single intravitreal injection of ranibizumab. Ranibizumab was effective in the treatment of this sight-threatening lesion in a patient with a history of kidney transplant. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - February 24, 2022 Category: Opthalmology Tags: Case Report Source Type: research