Lactate and Lactate Clearance as Predictors of One-Year Survival in Extracorporeal Cardiopulmonary Resuscitation – An International, Multicentre Cohort Study
Cardiac arrest is the third leading cause of mortality in Europe.[1] Survival after out-of-hospital cardiac arrest (OHCA) is dismal. The survival rate ranges from 8 to 14%.[2] In selected cases of cardiac arrest refractory to conventional cardiopulmonary resuscitation (CPR), the use of extracorporeal CPR (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has recently shown conflicting results in randomised controlled trials (RCT).[3 –5] These conflicting results might be due to multiple differences in study design (single-centre [ARREST and Prague OHCA study] versus multi-centre [INCEPTION], enrolmen...
Source: Resuscitation - February 23, 2024 Category: Emergency Medicine Authors: Tharusan Thevathasan, Emilie Gregers, Sivagowry Rasalingam M ørk, Sêhnou Degbeon, Louise Linde, Jo Bønding Andreasen, Morten Smerup, Jacob Eifer Møller, Christian Hassager, Helle Laugesen, Henryk Dreger, Anna Brand, Felix Balzer, Ulf Landmesser, Chris Tags: Clinical paper Source Type: research

Blood-brain barrier permeability for the first 24 hours in hypoxic-ischemic brain injury following cardiac arrest
This study aimed to explore the changes in blood-brain barrier (BBB) permeability and intracranial pressure (ICP) for the first 24 h after the return of spontaneous circulation (ROSC) and their association with injury severity of cardiac arrest. (Source: Resuscitation)
Source: Resuscitation - February 22, 2024 Category: Emergency Medicine Authors: Yeonho You, Jung Soo Park, Jin Hong Min, Wonjoon Jeong, Hong Joon Ahn, Yong Nam In, So Young Jeon, Jae Kwang Lee, Changshin Kang Tags: Clinical paper Source Type: research

Health-related quality of life and cognitive function after out-of-hospital cardiac arrest; a comparison of prehospital return-of-spontaneous circulation and refractory arrest managed with extracorporeal cardiopulmonary resuscitation
Extracorporeal cardiopulmonary resuscitation (ECPR) for selected refractory out-of-hospital cardiac arrest (OHCA) is increasingly used. Detailed knowledge of health-related quality of life (HRQoL) and long-term cognitive function is limited. HRQoL and cognitive function were assessed in ECPR-survivors and OHCA-survivors with prehospital return of spontaneous circulation after standard advanced cardiac life support (sACLS). (Source: Resuscitation)
Source: Resuscitation - February 22, 2024 Category: Emergency Medicine Authors: Emilie Gregers, Louise Linde, Joakim Bo Kunkel, Sebastian Wiberg, Peter Hasse M øller-Sørensen, Morten Smerup, Britt Borregaard, Henrik Schmidt, Jens Flensted Lassen, Jacob Eifer Møller, Christian Hassager, Helle Søholm, Jesper Kjærgaard Tags: Clinical paper Source Type: research

Multi-Phase Implementation of Automated External Defibrillator Use by Nurses During In-Hospital Cardiac Arrest and Its Impact on Survival
We sought to evaluate the impact of a medical directive allowing nurses to use defibrillators in automated external defibrillator-mode (AED) on in-hospital cardiac arrest (IHCA) outcomes. (Source: Resuscitation)
Source: Resuscitation - February 19, 2024 Category: Emergency Medicine Authors: Christian Vaillancourt, Manya Charette, Chelsea Lanos, Justin Godbout, Hannah Buhariwalla, Jennifer Dale-Tam, Marie-Joe Nemnom, Jamie Brehaut, George Wells, Ian Stiell Tags: Clinical paper Source Type: research

The value of scores predicting return of spontaneous circulation – confirmed again
In some cases of out-of-hospital cardiac arrest (OHCA), resuscitation works just great and survival with good neurological outcome can be achieved. However, there are also OHCA cases, in which it doesn ‘t. Especially in those cases, in which each team member is highly trained, aware of current guideline recommendations and gives it‘s best efforts, it leaves one wondering, what else we can do. (Source: Resuscitation)
Source: Resuscitation - February 16, 2024 Category: Emergency Medicine Authors: Camilla Metelmann, Bibiana Metelmann Tags: Editorial Source Type: research

One year after implementation of «super lay-rescuers» equipped with AED to improve survival of OHCA
To the Editor, (Source: Resuscitation)
Source: Resuscitation - February 16, 2024 Category: Emergency Medicine Authors: Fran çois Morin, Delphine Douillet, Emma Sokpoh, Lionel Lamhaut, Dominique Savary Tags: Letter to the Editor Source Type: research

Survival and Neurobehavioral Outcomes Following Out-of-Hospital Cardiac Arrest in Pediatric Patients with Pre-Existing Morbidity: An Analysis of the THAPCA Out-of-Hospital Arrest Data
The objective of this study was to determine if a similar association is seen in pediatric patients. (Source: Resuscitation)
Source: Resuscitation - February 15, 2024 Category: Emergency Medicine Authors: Sierra N. Foster, Kathryn Best, Dmitry Tumin, Xilong Li, Kaley Desher, Ravi R. Thiagarajan, Lakshmi Raman Tags: Clinical paper Source Type: research

Synthesizing and communicating scientific evidence into treatment recommendations using Artificial Intelligence: the “case” of temperature control after cardiac arrest
Dear Editor, (Source: Resuscitation)
Source: Resuscitation - February 15, 2024 Category: Emergency Medicine Authors: Federico Semeraro, Koenraad G. Monsieurs Tags: Letter to the Editor Source Type: research

Initial cardiac rhythms of out-of-hospital cardiac arrest victims with foreign body airway obstruction
To the Editor, (Source: Resuscitation)
Source: Resuscitation - February 14, 2024 Category: Emergency Medicine Authors: Tatsuya Norii, Yutaka Igarashi, Takuya Kogure Tags: Letter to the Editor Source Type: research

The association between mechanical CPR and outcomes from in-hospital cardiac arrest: An observational cohort study
Cardiac arrest is a highly morbid condition that affects nearly 200,000 hospitalized individuals each year in the United States [1 –4]. Apart from high-quality chest compressions and early defibrillation for cardiac arrest with initial shockable rhythms, few interventions have consistently demonstrated benefit for this critically-ill population [5]. Given the public health importance of in-hospital cardiac arrest (IHCA), ther e is an urgent need to identify effective therapies. (Source: Resuscitation)
Source: Resuscitation - February 9, 2024 Category: Emergency Medicine Authors: Conor Crowley, Justin Salciccioli, Wei Wang, Tomoyoshi Tamura, Edy Y. Kim, Ari Moskowitz, the American Heart Association's Get With The Guidelines ® – Resuscitation Investigators Tags: Clinical paper Source Type: research

Acute liver failure after out-of-hospital cardiac arrest: An observational study
Rationale: Apart from hypoxic hepatitis (HH), the hepatic consequences of out-of-hospital cardiac arrest (OHCA) have been little studied. This cohort study aimed to investigate the characteristics of liver dysfunction resulting from OHCA and its association with outcomes. (Source: Resuscitation)
Source: Resuscitation - February 7, 2024 Category: Emergency Medicine Authors: Marie-Charlotte Delignette, Neven Stevic, Fanny Leboss é, Eric Bonnefoy-Cudraz, Laurent Argaud, Martin Cour Tags: Clinical paper Source Type: research

The association of clinical, treatment, and demographic characteristics with rearrest in a national dataset
Following initial resuscitation from out-of-hospital cardiac arrest, rearrest frequently occurs and has been associated with adverse outcomes. We aimed to identify clinical, treatment, and demographic characteristics associated with prehospital rearrest at the encounter and agency levels. (Source: Resuscitation)
Source: Resuscitation - February 6, 2024 Category: Emergency Medicine Authors: Sarah Suchko, Tanner Smida, Remle P. Crowe, James J. Menegazzi, James F. Scheidler, Michael Shukis, P.S. Martin, James M. Bardes, David D. Salcido Tags: Clinical paper Source Type: research

The association of rearrest with clinical, treatment, and demographic characteristics in a national dataset
Following initial resuscitation from out-of-hospital cardiac arrest, rearrest frequently occurs and has been associated with adverse outcomes. We aimed to identify clinical, treatment, and demographic characteristics associated with prehospital rearrest at the encounter and agency levels. (Source: Resuscitation)
Source: Resuscitation - February 6, 2024 Category: Emergency Medicine Authors: Sarah Suchko, Tanner Smida, Remle P. Crowe, James J. Menegazzi, James F. Scheidler, Michael Shukis, P.S. Martin, James M. Bardes, David D. Salcido Tags: Clinical paper Source Type: research

Improving Response Time and Survival in ward based In-Hospital Cardiac Arrest: A Quality Improvement Initiative
Survival in cardiac arrest is associated with rapid initiation of high-quality cardiopulmonary resuscitation (CPR) and advanced life support. To improve ROSC rates and survival, we identified the need to reduce response times and implement coordinated resuscitation by dedicated cardiac arrest teams (CATs). We aimed to improve ROSC rates by 10% within 6 months, and subsequent survival to hospital discharge. (Source: Resuscitation)
Source: Resuscitation - February 6, 2024 Category: Emergency Medicine Authors: Carrie Kah-Lai Leong, Tan Hui Li, Edgarton Yi Hao Ching, Tien Jong-Chie Claudia Tags: Clinical paper Source Type: research

Resuscitation training in low-resources countries: a jointed project of the Italian Resuscitation Council and the NGO EMERGENCY
To the Editor, (Source: Resuscitation)
Source: Resuscitation - February 5, 2024 Category: Emergency Medicine Authors: Samanta DI MARCO, Matteo ROSSI, Monera Abd ALMHMOUD SIDIQ BABKER, Gabriella ARLOTTA, Alberto CUCINO, Niccol ò GRIECO, Claudia RUFFINI, Roberto MACCARONI, Alberto ZANIN, Manuela CORMIO, IRC-EMERGENCY working group Tags: Letter to the Editor Source Type: research