Early smoking lead to worse prognosis of COPD patients: a real world study
CONCLUSION: Early smoking COPD patients exhibited multiple adverse clinical outcomes, including heavy cigarette addiction, compromised pulmonary function, augmented left ventricular diameter, and elevated mortality risk. Additional, smoking cessation could not bring enough improvement of health state in early smoking COPD patients as late smoking COPD patients. Consequently, early intervention and specialized cessation approaches for younger smokers are of paramount importance in this context.PMID:38528530 | DOI:10.1186/s12931-024-02760-y (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Jiankang Wu Weiwei Meng Yiming Ma Zhiqi Zhao Ruoyan Xiong Jiayu Wang Rui Zhao Huihui Zeng Yan Chen Source Type: research
Associations of prior pulmonary tuberculosis with the incident COPD: a prospective cohort study
CONCLUSION: A history of PTB is an important independent risk factor for COPD. Clinical staff should be aware of this risk factor in patients with prior PTB, particularly in countries or regions with high burdens of PTB.PMID:38529640 | DOI:10.1177/17534666241239455 (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Zhilin Zeng Huilong Chen Zhonghe Shao Yunlong Guan Yuan Zhan Xi Cao Si Li Xingjie Hao Source Type: research
Pleural fluid characteristics of patients with COVID-19 infection
CONCLUSION: We demonstrate that 68.5% of pleural effusions in patients with COVID-19 infection were exudative and hypothesize that COVID-19-associated pleural effusions are likely to be exudative with WBC differential more likely to be predominantly lymphocytic.PMID:38529671 | DOI:10.1111/crj.13744 (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Ryan A Denu Victoria Forth Majid Shafiq Source Type: research
Value of rapid on-site evaluation combined with interventional pulmonology techniques in the diagnosis of pulmonary cryptococcosis
CONCLUSION: ROSE has commendable accuracy and timeliness, and CT-PNB offers further advantages in this regard. ROSE enhances the diagnostic efficiency of EBUS-TBLB for PC and is safe and effective.PMID:38529683 | DOI:10.1111/crj.13746 (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Jiaqi Cao Rong Zhou Qian He Ming Zhang Chunlai Feng Source Type: research
Diffuse Pulmonary Neuroendocrine Cell Hyperplasia with Parietal Pleural Involvement
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202307-1188IM. Online ahead of print.NO ABSTRACTPMID:38530087 | DOI:10.1164/rccm.202307-1188IM (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Alexandre Sayadi Marie-Pierre Debray Pierre Mordant Clairelyne Dupin Alice Guyard Source Type: research
Vitamin E Acetate is Associated with Select Proinflammatory Cytokines: An Analysis of a 2020-2022 Cohort of EVALI Patients
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202311-2155LE. Online ahead of print.NO ABSTRACTPMID:38530102 | DOI:10.1164/rccm.202311-2155LE (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Sean J Callahan Emily Beck Denitza Blagev Dixie Harris Michael Lanspa Samuel Brown Christopher A Reilly Robert Paine Iii Kristi J Warren Source Type: research
Of Mucus and Microbes: The Sticky Issue of Mucin-Microbiome Interactions in COPD
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202403-0506ED. Online ahead of print.NO ABSTRACTPMID:38530107 | DOI:10.1164/rccm.202403-0506ED (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Yvonne J Huang Source Type: research
Vive la Resistome: Are We Ready for a Metagenomics Revolution in Bronchiectasis?
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202402-0352ED. Online ahead of print.NO ABSTRACTPMID:38530113 | DOI:10.1164/rccm.202402-0352ED (Source: Respiratory Care)
Source: Respiratory Care - March 26, 2024 Category: Respiratory Medicine Authors: Shivani Singh Leopoldo N Segal Source Type: research
Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report
Respir Med Case Rep. 2024 Mar 13;48:102010. doi: 10.1016/j.rmcr.2024.102010. eCollection 2024.ABSTRACTCarbapenem-resistant Acinetobacter baumannii (CR-AB) is rarely found in community respiratory infections, and there are currently no reports of hemorrhagic bronchitis caused by its infection. This work presents a case of bronchial bleeding in a diabetic patient who acquired a community-acquired infection of CR-AB. Treatment with levofloxacin was unsuccessful, as the patient's hemoptysis symptoms recur. The patient was treated with minocycline based on the drug sensitivity test, resulting in the disappearance of hemoptysis ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Zifang Li Yu Sheng Dongdong Huang Source Type: research
Advancing Care in Severe Asthma: The Art of Switching Biologics
Adv Respir Med. 2024 Feb 21;92(2):110-122. doi: 10.3390/arm92020014.ABSTRACTBiologics targeting IgE, IL-5, IL-4/IL-13, and TSLP are crucial in severe asthma treatment. Research, including randomized controlled trials and real-world studies, has been conducted to assess their efficacy and identify patient characteristics that may predict positive responses. The effectiveness of switching biologics, especially given overlaps in treatment eligibility, and the clinical outcomes post-cessation are critical areas of investigation. This work reviews the effects of switching between these biologics and the indicators of treatment ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Silvano Dragonieri Andrea Portacci Vitaliano Nicola Quaranta Giovanna Elisiana Carpagnano Source Type: research
Ventilator-associated Brain Injury - VABI: A New Priority for Research in Mechanical Ventilation
Am J Respir Crit Care Med. 2024 Mar 25. doi: 10.1164/rccm.202401-0069VP. Online ahead of print.NO ABSTRACTPMID:38526447 | DOI:10.1164/rccm.202401-0069VP (Source: Respiratory Care)
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Thiago Bassi Shaurya Taran Timothy D Girard Chiara Robba Ewan C Goligher Source Type: research
Physiologic Effects of ECMO in Patients with Severe Acute Respiratory Distress Syndrome
CONCLUSIONS: In severe ARDS patients, increased ECMO blood flow rate resulting in higher SvO2 decreases pulmonary artery pressure, cardiac output, and right heart workload.PMID:38526489 | DOI:10.1164/rccm.202309-1688OC (Source: Respiratory Care)
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Elena Spinelli Marco Giani Douglas Slobod Bertrand Pavlovsky Michela di Pierro Stefania Crotti Alfredo Lissoni Giuseppe Foti Giacomo Grasselli Tommaso Mauri Source Type: research
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
Lancet Respir Med. 2024 Mar 22:S2213-2600(24)00028-6. doi: 10.1016/S2213-2600(24)00028-6. Online ahead of print.ABSTRACTThe current active-latent paradigm of tuberculosis largely neglects the documented spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic criteria for different tuberculosis states has limited the progress in research and product development that are needed to achieve tuberculosis elimination. We aimed to develop a new framework of classification for tuberculosis that accommodates key disease states but is sufficiently simple to support pragmatic research and implementa...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Anna K Coussens Syed M A Zaidi Brian W Allwood Puneet K Dewan Glenda Gray Mikashmi Kohli Tamara Kredo Ben J Marais Guy B Marks Leo Martinez Morten Ruhwald Thomas J Scriba James A Seddon Phumeza Tisile Digby F Warner Robert J Wilkinson Hanif Esmail Rein M Source Type: research
Hemorrhagic bronchitis caused by carbapenem-resistant Acinetobacter baumannii infection: A case report
Respir Med Case Rep. 2024 Mar 13;48:102010. doi: 10.1016/j.rmcr.2024.102010. eCollection 2024.ABSTRACTCarbapenem-resistant Acinetobacter baumannii (CR-AB) is rarely found in community respiratory infections, and there are currently no reports of hemorrhagic bronchitis caused by its infection. This work presents a case of bronchial bleeding in a diabetic patient who acquired a community-acquired infection of CR-AB. Treatment with levofloxacin was unsuccessful, as the patient's hemoptysis symptoms recur. The patient was treated with minocycline based on the drug sensitivity test, resulting in the disappearance of hemoptysis ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Zifang Li Yu Sheng Dongdong Huang Source Type: research
Advancing Care in Severe Asthma: The Art of Switching Biologics
Adv Respir Med. 2024 Feb 21;92(2):110-122. doi: 10.3390/arm92020014.ABSTRACTBiologics targeting IgE, IL-5, IL-4/IL-13, and TSLP are crucial in severe asthma treatment. Research, including randomized controlled trials and real-world studies, has been conducted to assess their efficacy and identify patient characteristics that may predict positive responses. The effectiveness of switching biologics, especially given overlaps in treatment eligibility, and the clinical outcomes post-cessation are critical areas of investigation. This work reviews the effects of switching between these biologics and the indicators of treatment ...
Source: Respiratory Care - March 25, 2024 Category: Respiratory Medicine Authors: Silvano Dragonieri Andrea Portacci Vitaliano Nicola Quaranta Giovanna Elisiana Carpagnano Source Type: research
