An analysis of the limitations and uncertainties of in vivo developmental neurotoxicity testing and assessment to identify the potential for alternative approaches
Publication date: Available online 8 August 2020Source: Reproductive ToxicologyAuthor(s): Martin Paparella, Susanne Hougaard Bennekou, Anna Bal-Price (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - August 13, 2020 Category: Toxicology Source Type: research

The unique applicability of the human placenta to the Adverse Outcome Pathway (AOP) concept: the placenta provides fundamental insights into human organ functions at multiple levels of biological organization
Publication date: September 2020Source: Reproductive Toxicology, Volume 96Author(s): Claudia Gundacker, Isabella Ellinger (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - August 13, 2020 Category: Toxicology Source Type: research

Folic acid reduces the ethanol-induced morphological and behavioral defects in embryonic and larval zebrafish (Danio rerio) as a model for fetal alcohol spectrum disorder (FASD)
Publication date: Available online 4 August 2020Source: Reproductive ToxicologyAuthor(s): Pabyton Gonçalves Cadena, Marilia Ribeiro Sales Cadena, Swapnalee Sarmah, James A. Marrs (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - August 5, 2020 Category: Toxicology Source Type: research

Replacing smoking with vaping during pregnancy: impacts on metabolic health in mice
Publication date: Available online 1 August 2020Source: Reproductive ToxicologyAuthor(s): Gerard Li, Yik L Chan, Baoming Wang, Sonia Saad, Brian G Oliver, Hui Chen (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - August 3, 2020 Category: Toxicology Source Type: research

Fine particulate matter reduces the pluripotency and proliferation of human embryonic stem cells through ROS induced AKT and ERK signaling pathway
Publication date: Available online 31 July 2020Source: Reproductive ToxicologyAuthor(s): Shilei Bi, Jingman Tang, Lizi Zhang, Lijun Huang, Jingsi Chen, Zhijian Wang, Dunjin Chen, Lili Du (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - August 1, 2020 Category: Toxicology Source Type: research

Urinary bisphenol A concentrations and in vitro fertilization outcomes among women from a fertility clinic
Publication date: Available online 25 July 2020Source: Reproductive ToxicologyAuthor(s): Paweł Radwan, Bartosz Wielgomas, Michał Radwan, Rafał Krasiński, Anna Klimowska, Dorota Kaleta, Joanna Jurewicz (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 27, 2020 Category: Toxicology Source Type: research

Placental Genomic and Epigenomic Signatures Associated with Infant Birth Weight Highlight Mechanisms Involved in Collagen and Growth Factor Signaling
Publication date: Available online 25 July 2020Source: Reproductive ToxicologyAuthor(s): Alexis Payton, Jeliyah Clark, Lauren Eaves, Hudson P. Santos, Lisa Smeester, Jacqueline T Bangma, T. Michael O’Shea, Rebecca C. Fry, Julia E. Rager (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 27, 2020 Category: Toxicology Source Type: research

Corrigendum to “Inhibitory effects of cigarette smoke extracts on neural differentiation of mouse embryonic stem cells” [Reprod. Toxicol. 95 (2020) 75–85]
Publication date: Available online 24 July 2020Source: Reproductive ToxicologyAuthor(s): Cho-Won Kim, Sung-Moo Lee, Eul-Bee Ko, Ryeo-Eun Go, Eui-Bae Jeung, Min-Seok Kim, Kyung-Chul Choi (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 24, 2020 Category: Toxicology Source Type: research

Effects of Bisphenol A on expression of genes related to amino acid transporters, insulin- like growth factor, aquaporin and amino acid release by porcine trophectoderm cells
Publication date: Available online 22 July 2020Source: Reproductive ToxicologyAuthor(s): Mohammed A. Elmetwally, Amal A. Halawa, Wanjin Tang, Guoyao Wu, Fuller W. Bazer (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 23, 2020 Category: Toxicology Source Type: research

Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure
Publication date: Available online 20 July 2020Source: Reproductive ToxicologyAuthor(s): Troy D. Hubbard, Amy Brix, Chad R. Blystone, Barry S. McIntyre, Keith Shockley, Helen Cunny, Suramya Waidyanatha, Katie J. Turner, Sandra McBride, Georgia K. Roberts (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 22, 2020 Category: Toxicology Source Type: research

Panax ginseng metabolite (GIM-1) modulates the effects of monobutyl phthalate (MBP) on the GPR30/GPER1 canonical pathway in human Sertoli cells
Publication date: Available online 16 July 2020Source: Reproductive ToxicologyAuthor(s): André Teves A.G. de Freitas, Cristiane Figueiredo Pinho, Ariana Musa de Aquino, Raquel Fantin Domeniconi, Luis Antonio Justulin, Wellerson Rodrigo Scarano (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 18, 2020 Category: Toxicology Source Type: research

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies
Publication date: Available online 16 July 2020Source: Reproductive ToxicologyAuthor(s): Jerrold J. Heindel, Scott Belcher, Jodi A. Flaws, Gail S. Prins, Shuk-Mei Ho, Jiude Mao, Heather B. Patisaul, William Ricke, Cheryl S. Rosenfeld, Ana M. Soto, Frederick S. vom Saal, R. Thomas Zoeller (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 18, 2020 Category: Toxicology Source Type: research

Assessing anti-estrogenic effects of AHR ligands in primary human and rat endometrial epithelial cells
Publication date: Available online 12 July 2020Source: Reproductive ToxicologyAuthor(s): AD van den Brand, E Rubinstein, PC de Jong, M van den Berg, MBM van Duursen (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 13, 2020 Category: Toxicology Source Type: research

Vanadium adversely affects sperm motility and capacitation status via protein kinase A activity and tyrosine phosphorylation
Publication date: Available online 10 July 2020Source: Reproductive ToxicologyAuthor(s): Jeong-Won Bae, Hobin Im, Ju-Mi Hwang, So-Hye Kim, Lei Ma, Hong Ju Kwon, Eungyung Kim, Myoung Ok Kim, Woo-Sung Kwon (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 11, 2020 Category: Toxicology Source Type: research

Adverse reproductive function induced by maternal BPA exposure is associated with abnormal autophagy and activating inflamation via mTOR and TLR4/NF-κB signaling pathways in female offspring rats
Publication date: Available online 4 July 2020Source: Reproductive ToxicologyAuthor(s): Yuan Meng, Zhao Yannan, Lin Ren, Sun Qi, Wei Wei, Jia Lihong (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - July 5, 2020 Category: Toxicology Source Type: research