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Cancer cells resist hyperthermia due to its obstructed activation of caspase 3
Publication date: Available online 26 February 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Xiaoren Tang, Feng Cao, Weiyuan Ma, Yinian Tang, Bushra Aljahdali, Mansour Alasir, i Erdjan Salih, Serge Dibart (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 27, 2020 Category: Cancer & Oncology Source Type: research

Cardiotoxicity of radiation therapy in esophageal cancer
Publication date: Available online 25 February 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Milan Vošmik, Miroslav Hodek, David Buka, Petra Sýkorová, Jakub Grepl, Petr Paluska, Simona Paulíková, Igor Sirák (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 26, 2020 Category: Cancer & Oncology Source Type: research

Detection of radiation induced cardiotoxicity: role of echocardiography and biomarkers
Publication date: Available online 24 February 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Radek PudilAbstractWe review the role of echocardiography and biomarkers in detection of radiation-induced cardiac toxicity (RICT). RICT is related to micro- and macrovascular damage which induce inflammation, endothelial dysfunction, accelerated atherosclerosis, myocyte degeneration and fibrosis. The process is cumulative dose to the heart and target volume dependent. Furthermore, the damage of the heart is frequently potentiated by the adjunctive chemotherapy. The clinical manifestations of RICT may acutely d...
Source: Reports of Practical Oncology and Radiotherapy - February 24, 2020 Category: Cancer & Oncology Source Type: research

Stereotactic Ablative Radiotherapy for Bone Metastasis of Gastrointestinal Stromal Tumor: Case Report and Review of the Literature
Conclusion: SABR should be considered as a treatment option in GIST with bone metastasis. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 24, 2020 Category: Cancer & Oncology Source Type: research

Baseline Karnofsky performance status is independently predictive of death within 30 days of palliative intracranial radiation therapy completion for metastatic disease
ConclusionsOur findings indicate that baseline KPS < 70 is independently predictive of death within 30 days of palliative intracranial RT, and that a large majority of patients who died within 30 days received at least 10 fractions. These results indicate that for poor performance status patients requiring palliative intracranial radiation, hypofractionated RT courses should be strongly considered. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 24, 2020 Category: Cancer & Oncology Source Type: research

Low-Dose Radiation Therapy for Benign pathologies
Publication date: Available online 22 February 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Laura Torres Royo, Gabriela Antelo Redondo, Miguel Árquez Pianetta, Meritxell Arenas PratAbstractRadiotherapy (RT) has always been a mainstay for malignant tumors therapy, but it is also used for benign pathology. The application of low or intermediate doses of RT has been widely studied. This topic was presented and discussed in the last XX GOCO (Grup Oncològic Català-Occità) meeting. The aim of this article is to review the indications of low dose irradiation (LD-RT), total dose and different fractionatio...
Source: Reports of Practical Oncology and Radiotherapy - February 23, 2020 Category: Cancer & Oncology Source Type: research

Biochemical Relapse Free Survival Rate in Patients with Prostate Cancer treated with External Radiotherapy: Outcomes obtained at the CMN Siglo XXI Hospital de Oncología, CMN 20 de Noviembre and Hospital General de México of the México City
ConclusionsThe RT techniques for the treatment of PCa are statistically equivalent with respect to the bRFS rate. This paper confirms that the bRFS rates of Mexican PCa patients who were treated with conventional vs. hypofractionated schemes do not differ significantly. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Difference between the effective atomic numbers and monochromatic CT numbers for commercially available dual-energy CT
ConclusionsThe accuracy of the Zeff values with dual-source DECT was good in agreement in the Multi-Energy phantom. The single-source fast kilovoltage switching type DECT could reduce the noise and accuracy of the Zeff values than that with single-source DECT for the varying concentrations of iodinated contrast medium.Advances in knowledgeThe accuracy and precision of the Zeff values of the contrast medium with the single-source fast kilovoltage switching type DECT could be sufficient with human equivalent materials. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

The Impact of Local Control Timing in Ewing Sarcoma
ConclusionDelay in definitive therapy, local control with radiation as opposed to surgery and poor post-chemotherapy tumor necrosis predict inferior OS in ES. Adopting strategies to minimize delay in local control could improve survival outcomes. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Provider Delay in Treatment Initiation and its Influence on Survival Outcomes in Women with Operable Breast Cancer
ConclusionsThe initiation of treatment within the first 45 days of diagnosis of BrCr in women portends better survival compared with those who began treatment longer than 45 days from diagnosis. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Acute Toxicity Outcomes And Dosimetric Implications From Incidental Irradiation Of Adjacent Tissues In Tangent Field Hypofractionated Breast Radiotherapy
ConclusionsFor HF-WBI, doses to nTIB over the prescription predicted acute toxicities independent of breast doses. These data support inclusion of TIB as a region of interest in treatment planning and protocol design (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Stereotactic Body Radiation Therapy and Radiofrequency Ablation for the Treatment of Liver Metastases: How and When?
Publication date: Available online 21 February 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Alberto Cacciola, Silvana Parisi, Consuelo Tamburella, Sara Lillo, Gianluca Ferini, Laura Molino, Giuseppe Iatì, Antonio Pontoriero, Antonio Bottari, Silvio Mazziotti, Giuseppe Cicero, Fabio Minutoli, Alfredo Blandino, Stefano PergolizziAbstractLimited liver metastases represent a clinical challenge. Surgical approach is the most frequently reported treatment option, however, some patients are not eligible for surgical interventions. Relatively recent technologic advances have permitted the safe use of ablativ...
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Post-chemotherapy target volumes are safe as boost volume for intact breast radiotherapy in locally advanced breast cancer
ConclusionsDelineation of post NACT excision cavity as POC for boost radiotherapy is safe. Clips serve as a good surrogate for CTV delineation in 75% patients. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Prospective evaluation of the setup errors and its impact on safety margin for cervical cancer pelvic conformal radiotherapy
ConclusionThe computed SE helps defining SM, and it may differ between institutions. In our study, the calculated SM was approximately 8 mm in the Z-axis, 7 mm in X and Y axis for pelvic conformal radiotherapy. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 22, 2020 Category: Cancer & Oncology Source Type: research

Acknowledgement of reviewers
Publication date: January–February 2020Source: Reports of Practical Oncology & Radiotherapy, Volume 25, Issue 1Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 1, 2020 Category: Cancer & Oncology Source Type: research