Reports of Practical Oncology and Radiotherapy 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Cardiac toxicity of lung cancer radiotherapy
Publication date: January–February 2020Source: Reports of Practical Oncology & Radiotherapy, Volume 25, Issue 1Author(s): Radovan VojtíšekAbstractRadical radiotherapy of lung cancer with dose escalation has been associated with increased tumor control. However, these attempts to continually improve local control through dose escalation, have met mixed results culminating in the findings of the RTOG trial 0617, where the heart dose was associated with a worse overall survival, indicating a significant contribution to radiation-induced cardiac morbidity. It is, therefore, very likely that poorly understood cardiac toxici...
Source: Reports of Practical Oncology and Radiotherapy - November 15, 2019 Category: Cancer & Oncology Source Type: research
Determination of inflection points of CyberKnife dose profiles within acceptability criteria of deviations in measurements
ConclusionDerivatives of the interpolated profiles showed that locations of IPs and 50% isodose points coincide. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 14, 2019 Category: Cancer & Oncology Source Type: research
Giant locally advanced and metastatic squamous cell skin carcinoma of head and neck region: case report
ConclusionDespite the seemingly incurable finding it is always necessary to consider radical treatment regardless of the patient´s age. Curative treatment could achieve long term remission in the group of older patients. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 14, 2019 Category: Cancer & Oncology Source Type: research
Biological dose-enhancement analysis with Monte Carlo simulation for Lipiodol for photon beams
ConclusionsThe lower-energy and higher-dose-rate beams were contributed to the biological dose. The Lipiodol caused the enhancement of the physical dose and biological effectiveness.Advances in knowledgeThe biological dose enhancement (DbioEF) should be considered in the high-density material such as the Lipiodol. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 9, 2019 Category: Cancer & Oncology Source Type: research
SPECT-CT localization of axillary sentinel lymph nodes for radiotherapy of early breast cancer
ConclusionSPECT-CT mapping of ASLNs in women with cT1-2N0M0 breast cancer reveals their variable localization. This information can be important for planning of radiation treatment in women that underwent breast conserving surgery without an axillary surgery. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 9, 2019 Category: Cancer & Oncology Source Type: research
Increased radiation toxicity with germline ATM variant of uncertain clinical significance
ConclusionOur data illustrates that patients with germline heterozygous ATM mutations can have widely varying clinical effects with radiation therapy. Given the possibility of unpredictable deleterious effects, our study highlights the importance of caution and careful consideration when devising the multi-modality management strategy in these patients. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 6, 2019 Category: Cancer & Oncology Source Type: research
Detailed analysis of dose difference in using water as tissue-equivalent material in 252Cf brachytherapy
ConclusionAssuming water as a tissue-equivalent material, although leads to overestimation of dose rate (except in the case of adipose tissue), is acceptable and suitable for use in 252Cf brachytherapy treatment planning systems based on the recommendation by the ICRU that the uncertainties in dose delivery in radiotherapy should be lower than 5%. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 5, 2019 Category: Cancer & Oncology Source Type: research
Frameless radiosurgery for intraocular metastatic tumor: Case report
ConclusionThe frameless robotic radiosurgery system is feasible and comfortable option for patients with intraocular metastases. Treatment planning and delivery requires an experienced interdisciplinary team. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 5, 2019 Category: Cancer & Oncology Source Type: research
Dose distribution comparison in volumetric-modulated arc therapy plans for head and neck cancers with and without an external body contour extended technique
ConclusionsAn EBCT is needed to estimate the proper dose at object volumes near the patient’s skin and can improve the accuracy of the calculated dose at target volumes. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 3, 2019 Category: Cancer & Oncology Source Type: research
Intrinsic radiosensitivity, genomic-based radiation dose and patterns of failure of penile cancer in response to adjuvant radiation therapy
ConclusionsThe majority of PeSCC are intrinsically radioresistant with a low GARD-based therapeutic effect from PORT dose of 50 Gy, consistent with the observed high rate of LRR in the clinical cohort. A GARD-based strategy will allow personalizing PORT dose prescription to individual tumor biology and improve outcomes. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 2, 2019 Category: Cancer & Oncology Source Type: research
Dose to swallowing structures and dysphagia in head and neck Intensity Modulated Radiation Therapy – A long term prospective analysis
ConclusionGiving a constraint to the swallowing structure and limiting it to <45 Gy resulted in earlier recovery of swallowing function resulted in good physical, mental and social well being of the patients when compared to those who received>45 Gy. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 2, 2019 Category: Cancer & Oncology Source Type: research
Feasibility study on the use of 230 MeV proton cyclotron in proton therapy centers as a spallation neutron source for BNCT
ConclusionsResults for 230 MeV protons show that with proposed BSA, proton beam current about 5.75 μA is required for this purpose. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - October 31, 2019 Category: Cancer & Oncology Source Type: research
Radiosurgery for brain metastases from ovarian cancer: an analysis of 25 years’ experience with Gamma Knife treatment
ConclusionsGKRS for BM from ovarian cancer is a safe and effective modality. Our findings are in agreement with the recent literature indicating that women with brain metastases from ovarian cancer will benefit with radiosurgery and may achieve long term survival with brain control. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - October 31, 2019 Category: Cancer & Oncology Source Type: research
A case of Lymphoepithelioma-like carcinoma (LELC) developed in the rectum
Publication date: November–December 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 6Author(s): Haruka Oi, Satoshi Yamamoto, Yoshiharu Kono, Yukiyoshi MasakiAbstractLymphoepithelioma-like carcinoma (LELC) is histologically similar in form to nasopharyngeal carcinoma (NPC) and is an epithelial tumor that is suggested to be involved in infection with Epstein-Barr virus (EBV), but it is rare to occur in the colon. A 35-year-old woman was found to have a rectal wall thickening by follow-up computed tomography (CT) image after sigmoidectomy and left salpingo-oophorectomy. Biopsy under colonoscopy re...
Source: Reports of Practical Oncology and Radiotherapy - October 30, 2019 Category: Cancer & Oncology Source Type: research
Cardiotoxicity of mediastinal radiotherapy
ConclusionsStudies uniformly show a linear radiation dose-response relationship between mean absorbed dose to the heart (heart-Dmean) and the risk of dying as a result of cardiac disease, particularly when heart-Dmean exceeds 5 Gy. Limited data are available regarding dose-volume predictors for heart substructures and the risk of subsequent cardiac toxicity. An individual patient’s cardiotoxicity risk can be modified with advanced treatment planning techniques, including deep inspiration breath hold. Proton therapy is currently showing advantages in improving treatment planning parameters when compared to advanced p...
Source: Reports of Practical Oncology and Radiotherapy - October 30, 2019 Category: Cancer & Oncology Source Type: research
