Total antioxidant and oxidant status of plasma and renal tissue of cisplatin-induced nephrotoxic rats: protection by floral extracts of Calendula officinalis Linn.
Authors: Verma PK, Raina R, Sultana M, Singh M, Kumar P Abstract Absract The present study was aimed to determine the total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of plasma and renal tissue in cisplatin (cDDP) induced nephrotoxic rats and its protection by treatments with floral extracts of Calendula officinalis Linn. Treatment with cDDP elevated (p 
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Protective effects of thymoquinone against apoptosis and oxidative stress by arsenic in rat kidney.
Authors: Sener U, Uygur R, Aktas C, Uygur E, Erboga M, Balkas G, Caglar V, Kumral B, Gurel A, Erdogan H Abstract We aimed to investigate the protective role of thymoquinone (TQ) by targeting its antiapoptotic and antioxidant properties against kidney damage induced by arsenic in rats. We have used the 24 male Sprague-Dawley rats. Rats were divided into three groups. Physiological serum in 10 mL/kg dose as intragastric was given to the control group. Sodium arsenite (10 mg/kg, intragastric by gavage for fifteen days) was given to the arsenic group. Sodium arsenite (10 mg/kg, intragastric by gava...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Oral manifestations in chronic uremia patients.
Authors: Dioguardi M, Caloro GA, Troiano G, Giannatempo G, Laino L, Petruzzi M, Lo Muzio L Abstract The incidence of chronic renal failure (CRF) is approximately 200 cases per million people in different Western countries. Recent data indicate that the incidences of these pathologies are increasing. Ninety percent of patients with CRF report oral signs and symptoms that affect both the bone and soft tissues. A broad range of lesions may be observed in chronic uratemia patients, including the following: gingival hyperplasia, enamel hypoplasia, petechiae, gingival bleeding, and others lesions. These patients require ...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Kidney disease progression in patients of upper tract urothelial carcinoma following unilateral radical nephroureterectomy.
Authors: Lee KH, Chen YT, Chung HJ, Liu JS, Hsu CC, Tarng DC Abstract OBJECTIVES: To compare the renal outcomes in patients of unilateral renal cell carcinoma (RCC) with upper tract urothelial carcinoma (UTUC) following surgical resection of the tumor-bearing kidney, and to investigate the potential predictors in renal function decline. PATIENTS AND METHODS: In this retrospective cohort study, 319 RCC patients undergoing radical nephrectomy (RN) and 297 UTUC patients undergoing radical nephroureterectomy were recruited from a tertiary medical center between 2001 and 2010. Demographic data, co-morbidity, smoking...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The association of oxidant-antioxidant status in patients with chronic renal failure.
Authors: Aziz MA, Majeed GH, Diab KS, Al-Tamimi RJ Abstract Oxidative stress has been linked to disease progression, including chronic renal failure (CRF). The aim of the present study was to determine malondialdehyde (MDA) as a sign of lipid peroxidation, and to investigate the association between antioxidant activities and three trace elements, in 49 patients with CRF. The erythrocyte and plasma trace elements [selenium (Se), zinc (Zn), and copper (Cu)] and antioxidant defense levels were determined: glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), vitamins E and C. The obtained values we...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Interleukin-10-1082 G/a polymorphism and acute renal graft rejection: a meta-analysis.
CONCLUSIONS: This meta-analysis suggests that IL-10-1082 G/A polymorphism is not significantly associated with AR risk in renal transplant recipients. PMID: 26524497 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

C-reactive protein but not hepcidin, NGAL and transferrin determines the ESA resistance in hemodialysis patients.
Authors: Yılmaz I, Ozkok A, Kostek O, Kolukısa A, Duran I, Odabaş AR, Kemal Işman F, Işbilen Başok B Abstract BACKGROUND: Erythropoiesis-stimulating agents (ESA) are commonly used for the treatment of anemia in hemodialysis (HD) patients, however, 5-10% of these patients have resistance to ESA treatment. Hepcidin and neutrophil-gelatinase associated lipocalin (NGAL) are induced by inflammation and these proteins may take role in ESA resistance. Herein, we aimed to investigate the effects of serum hepcidin, NGAL, transferrin and C-reactive protein (CRP) levels on ESA resistance in HD patients. METHODS: A t...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Lymphocyte depletion and subset alteration correlate to renal function in chronic kidney disease patients.
Authors: Xiang FF, Zhu JM, Cao XS, Shen B, Zou JZ, Liu ZH, Zhang H, Teng J, Liu H, Ding XQ Abstract BACKGROUND: It is widely accepted that chronic renal failure is associated with severe alterations of immune system. However, few studies looked into the immune alteration in earlier stage of chronic kidney disease (CKD) patients. To characterize immune defect in CKD patients, we performed lymphocyte subset analysis and explored its relationship to renal function in this population. METHODS: 472 CKD patients were enrolled in this study. Lymphocyte subsets (CD19(+), CD3(+), CD3(+)CD4(+), CD3(+)CD8(+), CD56(+)CD16(...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Neutrophil-lymphocyte ratio predicts cardiovascular and all-cause mortality in hemodialysis patients.
Authors: Neuen BL, Leather N, Greenwood AM, Gunnarsson R, Cho Y, Mantha ML Abstract Neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been shown to predict mortality in patients with malignancies, ischemic heart disease and peripheral vascular disease. Its prognostic value in hemodialysis patients is unclear. The aims of this study were to: (i) explore the relationship between NLR and other biochemical parameters and (ii) to examine the value of NLR as a predictor of cardiovascular and all-cause mortality in hemodialysis patients. The study included all the incident hemodialysis patien...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Increased microalbuminuria prevalence among patients with nonalcoholic fatty liver disease.
Authors: Kasapoglu B, Turkay C, Yalcın KS, Boga S, Bozkurt A Abstract AIM: To determine the prevalence of microalbuminuria, that is an indirect predictor of coronary artery disease, among non-obese and non-diabetic patients with fatty liver disease. MATERIAL AND METHOD: This retrospective study was carried out on non-obese (body mass index (BMI) 
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Study on 3'-UTR length polymorphism in peripheral blood mononuclear cells of uremia patient.
CONCLUSION: There were significant differences in 3'-UTR lengths between uremic patients and healthy controls, and analysis of the differential genes may contribute to the understanding of uremia pathogenesis. PMID: 26554293 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Restless-legs syndrome and insomnia in hemodialysis patients.
CONCLUSIONS: HD patients commonly have RLS and insomnia. Insomnia and diabetes mellitus seem to be major factors underlying RLS in HD patients. Furthermore, depression and RLS seem to be closely related to insomnia in these patients. Treatment of depression, insomnia, and RLS may be beneficial to improve quality of life in HD patients. PMID: 26554439 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Effect of polyflux membranes on the improvement of hemodialysis-associated eosinophilia: a case series.
This study aimed to investigate the use of Polyflux membranes to improve HAE. Thirty-one patients suffering from HAE were included. Patients were dialyzed with polysulfone membranes when they developed HAE. After that, patients were dialyzed with Polyflux membranes three times every week, 4 h every time without changing the dialysis parameters and medication. Levels of peripheral eosinophils, hsCRP, IgE, C3a, IL-5 and peripheral CD4+ lymphocytes and CD8+ lymphocytes were assessed before Polyflux treatment, and at 4th, 8th and 12th weeks of treatment. Any symptoms including chest tightness and skin itching were obser...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Serum NGAL, cystatin C and urinary NAG measurements for early diagnosis of contrast-induced nephropathy in children.
CONCLUSION: In the first 24 h, s-cystatin-C, s-NGAL and especially u-NAG/creatinine ratio showed promise as biomarkers, but eGFR is not adequate for early diagnosis of CIN. Sequential measurement of biomarkers may contribute to more accurate diagnosis of AKI. PMID: 26584598 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Association of the methylenetetrahydrofolate reductase gene C677T polymorphism with the risk of male infertility: a meta-analysis.
In conclusion, this meta-analysis is in favor that the MTHFR C677T polymorphism is capable of causing male infertility susceptibility, especially in Asians and the subgroup of azoospermia. PMID: 26584688 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Risk factor(s) related to high membrane permeability in peritoneal dialysis.
In this study, we aimed to investigate possible risk factor(s) related to high peritoneal membrane permeability. PATIENTS AND METHOD: The study included 475 PD patients (46.1 ± 14.5 years of mean age; 198 female and 277 male). The patients were divided two groups according to peritoneal equilibration test (PET) result: high-permeability group (high and high-average) and low- permeability group (low-average and low). RESULTS: In both the univariate and multivariate logistic regression analyses, it was found that diabetes mellitus and hypoalbuminemia was significantly associated with high periton...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Association of plasminogen activator inhibitor-1 gene polymorphism and type 2 diabetic nephropathy.
Authors: Xu F, Liu H, Sun Y Abstract BACKGROUND: We investigated the relationship between plasminogen activator inhibitor-1 (PAI-1) 4G/5G insertion/deletion polymorphism and prevalence of diabetic nephropathy (DN) in Chinese patients. METHODS: A total of 107 patients with type 2 diabetes were randomly recruited in the study, and 102 healthy subjects were selected as Control. Patients were divided into three groups according to their urinary albumin-creatinine ratio (UACR). Group A (n = 44), had patients without DN (serum creatinine
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Evaluation of serum NGAL and hepcidin levels in chronic kidney disease patients.
Authors: Avci Çiçek E, Rota S, Dursun B, Kavalci E Abstract Cardiovascular disease is the major cause of death in chronic kidney disease (CKD) patients. The main underlying reason is inflammation. In CKD, interleukin-6 and hypersensitive C-reactive protein are known to be used for the evaluation of inflammation and serum levels increase with decreased creatinine clearance. Neutrophil gelatinase-associated lipocalin (NGAL) and hepcidin are also considered to be effective in the assessment of inflammatory conditions. The possible interactions of NGAL and hepcidin with inflammatory markers in CKD patient...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Prevalence and determinants of the metabolic syndrome among subjects with advanced nondiabetes-related chronic kidney disease in Gran Canaria, Spain.
Conclusions The prevalence of the metabolic syndrome among subjects with advanced nondiabetes-related CKD is high, and greater than that observed in general Canarian population of similar age groups. Age and family history of diabetes are the two factors more strongly associated with the metabolic syndrome in this population. PMID: 26627145 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Polymorphisms in NADPH oxidase CYBA gene modify the risk of ESRD in patients with chronic glomerulonephritis.
Authors: Zhou H, Chen M, Zhu Y, Wang B, Liu XN, Zuo Z, Tang FY Abstract End-stage renal disease (ESRD) was defined as start of renal replacement therapy or death due to kidney disease. However, death due to acute kidney injury was not included. It typically occurs when chronic renal failure progresses to a point where the kidneys are permanently functioning at less than 10% of their capacity. Oxidative stress (OS) plays a crucial role in ESRD. Nicotinamide adenine dinucleotide phosphate (NADPH) is one of the most important enzymes during oxidative stress. Cytochrome b light chain (CYBA), encoded by a polymorphic ge...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Effects of acute kidney injury on clinical outcomes in patients with upper gastrointestinal bleeding.
Authors: Cakmak U, Merhametsiz O, Gok Oguz E, Ercan Z, Haspulat A, Ozkan SK, Canbakan B, Deniz Aylı M Abstract Aim Upper gastrointestinal bleeding (UGIB) is a very frequently encountered condition that has a high morbidity and which increases treatment costs. Duration of hospital stay and mortality increases in patients with UGIB complicated by acute kidney injury (AKI). The aim of this study was to reveal risk factors in patients with UGIB developing AKI and to compare clinical outcomes and hospital costs between patients with UGIB developing AKI and those with UGIB not developing AKI. Material and methods This r...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Steroid-resistant nephrotic syndrome caused by novel WT1 mutation inherited from a mosaic parent.
We report here a novel WT1 mutation associated with SRNS in a female patient, which leads to a Cys428Ser substitution on protein level, affecting one of the cysteine residues responsible for zinc binding in the second zinc finger domain. Surprisingly, the mutation identified in the patient was found to be inherited from the healthy mosaic mother. The presence of mosaicism was confirmed using quantitative polymerase chain reaction (PCR) high-resolution melting. The clinical implications of this finding for the family are discussed. PMID: 26627896 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The role of the uncertainty of measurement of serum creatinine concentrations in the diagnosis of acute kidney injury.
Authors: Kin Tekce B, Tekce H, Aktas G, Uyeturk U Abstract Uncertainty of measurement is the numeric expression of the errors associated with all measurements taken in clinical laboratories. Serum creatinine concentration is the most common diagnostic marker for acute kidney injury. The goal of this study was to determine the effect of the uncertainty of measurement of serum creatinine concentrations on the diagnosis of acute kidney injury. We calculated the uncertainty of measurement of serum creatinine according to the Nordtest Guide. Retrospectively, we identified 289 patients who were evaluated for acute kidney...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

A review of the impact of oxidative stress and some antioxidant therapies on renal damage.
Authors: Tamay-Cach F, Quintana-Pérez JC, Trujillo-Ferrara JG, Cuevas-Hernández RI, Del Valle-Mondragón L, García-Trejo EM, Arellano-Mendoza MG Abstract An increase in the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) leads to complications during chronic kidney disease (CKD). This increase essentially derives from the impairment of natural antioxidant systems of the organism. The resulting oxidative stress produces damage to kidney tissue, especially by affecting nephrons and more generally by disrupting the function and structure of the glomerulus and ...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The role of DJ-1/Nrf2 pathway in the pathogenesis of diabetic nephropathy in rats.
Authors: Sun Q, Shen ZY, Meng QT, Liu HZ, Duan WN, Xia ZY Abstract Diabetic nephropathy (DN) is one of the most common chronic complications of diabetes, which is associated with an increased oxidative stress induced by hyperglycemia and alterations in DJ-1/NF-E2-related factor-2 (Nrf2) pathway. In the present study, we investigated the role and the proper time nodes of DJ-1/Nrf2 pathway in the pathogenesis of DN. Diabetes mellitus (DM) model of rats was induced by intraperitoneal injection of streptozotocin (STZ) on male Sprague-Dawley (SD) rats. Then, the diabetic rats were divided into 4, 8 and 12 weeks groups. ...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Genotype polymorphisms of genes regulating nitric oxide synthesis determine long-term arteriovenous fistula patency in male hemodialysis patients.
Authors: Lee KH, Tsai WJ, Chen YW, Yang WC, Lee CY, Ou SM, Chen YT, Chien CC, Lee PC, Chung MY, Lin CC Abstract Objectives Nitric oxide (NO) is a pivotal vasoactive substance modulating arteriovenous fistula (AVF) patency for hemodialysis (HD). Since genetic background could be the predicting factor of AVF malfunction, we aimed to investigate whether the NO-related genotype polymorphisms determine AVF survival rates. Methods This is a retrospective, observational, multi-center study involving eight HD units in Taiwan, enrolled 580 patients initiating maintenance HD via AVFs. Genotype polymorphisms of NO-biosynthesi...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The expression of response gene to complement 32 on renal ischemia reperfusion injury in rat.
Authors: Sun L, Shen YL, Liu HJ, Hu YJ, Kang YL, Huang WY Abstract To investigate the expression of response gene to complement 32 (RGC32) in rat with acute kidney injury (AKI) and to explore the role of RGC32 in renal injury and repair induced by ischemia reperfusion. Rats were randomly divided into two groups, including sham operation group (n = 48) and acute ischemia reperfusion injury (IRI) group (n = 48). Rats were sacrificed following reperfusion 2 h, 6 h, 24 h, 48 h, 72 h, 1 week (w), 2 w, and 4 w. The distribution and expression of RGC32 in rena...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Angiotensin II induces reorganization of the actin cytoskeleton and myosin light-chain phosphorylation in podocytes through rho/ROCK-signaling pathway.
Authors: Wang S, Chen C, Su K, Zha D, Liang W, Hillebrands JL, Goor Hv, Ding G Abstract Aims In the present study, we have evaluated the effect of angiotensin II (Ang II) on actin cytoskeleton reorganization and myosin light-chain (MLC) phosphorylation in podocytes to demonstrate whether the Rho/Rho-associated coiled kinase (ROCK) pathway is involved podocyte injury. Methods Eighteen male Sprague-Dawley rats were divided into three groups and treated with Ang II, saline or telmisartan. Morphological changes were studied at 28 days after treatment. Immunohistochemistry and Western blotting were used to determine the...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Effect of parathyroid hormone on serum magnesium levels: the neglected relationship in hemodialysis patients with secondary hyperparathyroidism.
Authors: Fang L, Tang B, Hou D, Meng M, Xiong M, Yang J Abstract Chronic kidney disease-mineral and bone disorder (CKD-MBD) is an important complication in patients with end-stage renal disease. Since recent studies have shown that magnesium (Mg) disturbance plays an important role in CKD-MBD and cardiovascular mortality, the interest on magnesium has grown recently. Although much concern focused on the effect of Mg on parathyroid hormone (PTH) levels, however, the influence of PTH on serum Mg levels is nearly unexplored. To evaluate the effect of PTH on serum Mg levels, we first described the relationship between ...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Prevalence of various comorbidities among veterans with chronic kidney disease and its comparison with other datasets.
Authors: Patel N, Golzy M, Nainani N, Nader ND, Carter RL, Lohr JW, Arora P Abstract Chronic kidney disease (CKD) has a complicated interrelationship with various comorbidities. The purpose of this study was to describe the prevalence of various comorbidities among veterans with CKD and compare it with other datasets like Kidney Early Evaluation Program (KEEP), National Health and Nutrition Examination Survey (NHANES) and Medicare. Patients who had at least one outpatient visit in year 2007 (1 January 2007 to 31 December 2007) were included in the study (n =  75,787). Glomerular filtration rate...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Cisplatin and herbal antioxidants: protective effect of pomegranate seed oil against cisplatin-induced nephrotoxicity in rat.
Authors: Nematbakhsh M PMID: 26707061 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Vitamin D receptor activation with calcitriol for reducing urinary angiotensinogen in patients with type 2 diabetic chronic kidney disease.
Authors: Tiryaki Ö, Usalan C, Sayiner ZA Abstract Background Recently, it has been reported that urinary angiotensinogen levels is a specific index of the intrarenal renin-angiotensin-aldosterone system (RAAS) status and it is significantly correlated with urinary albumin:creatinine (Cr) ratio in hypertensive patients. The aim of the present study was to assess the effect of activation of the Vitamin D receptor with calcitriol on albuminuria and urinary angiotensinogen as a novel biomarker of the intra-renal RAAS status in patients with diabetic nephropathy (DN). Methods Ninety-eight patients with type 2 diabe...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Curcumin protects against gallic acid-induced oxidative stress, suppression of glutathione antioxidant defenses, hepatic and renal damage in rats.
Authors: Abarikwu SO, Durojaiye M, Alabi A, Asonye B, Akiri O Abstract Curcumin (Cur) and gallic acid (Gal) are major food additives. Cur has well-known antioxidant properties, whereas Gal has both antioxidant and pro-oxidant effects. The present study investigated the effects of oral administration of Gal with or without Cur on antioxidant enzymes activities, glutathione (GSH) and the enzymes in its metabolism in rat liver in vivo and markers of tissue damage in the serum. Results showed that the increase in serum creatinine level, alkaline phosphatase and lactate dehydrogenase activities by Gal treatment were inh...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Assessing association between duration of postoperative acute kidney injury and in-hospital mortality after noncardiac surgery.
Authors: Liu Y, Xue FS, Liu GP, Sun C PMID: 26707274 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

HIF-1α mediates Hypoxia-induced epithelial-mesenchymal transition in peritoneal mesothelial cells.
In this study, we, therefore, investigated the effects of hypoxia on EMT in mesothelial cells. Human mesothelial (MeT-5A) cells and primary-cultured rat mesothelial cells were cultured under hypoxic conditions (1% O2) for up to 72 h. Changes in cell type were then determined by investigating changes in morphology and in expression of epithelial (E-cadherin and occludin) and mesenchymal (fibronectin-1, vimentin and α-smooth muscle actin) cell markers. In some cases, MeT-5A cells were cultured under hypoxic conditions with a HIF-1α inhibitor and then assessed for changes in morphology and for altered expression o...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Colchicine resistance and low vitamin D in familial Mediterranean fever.
Authors: Anık A, Abacı A, Ünsal E, Makay B PMID: 26707648 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Effect of hemodialysis on intraocular lens power calculation.
Authors: Çalışkan S, Çelikay O, Biçer T, Aylı MD, Gürdal C Abstract Background To evaluate changes in ocular biometric parameters after hemodialysis (HD) in patients with end-stage renal disease (ESRD). Methods Forty eyes of 40 patients undergoing HD were included in this cross-sectional study. Keratometry (K) readings, white-to-white (WTW) distance, central corneal thickness (CCT), anterior chamber depth (ACD), pupil diameter, lens thickness (LT), axial length (AL), and intraocular lens (IOL) power calculation were measured with Lenstar LS 900 (Haag Streit AG, Koeniz, Switzerland) befo...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Middle East respiratory syndrome coronavirus infection: a short note on cases with renal failure problem.
Authors: Joob B, Wiwanitkit V PMID: 26726780 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Methotrexate renal clearance by low-dose dopamine in severe nephrotoxicity.
Authors: Grosjean F, Sepe V, Gotti M, Rossi M, Dal Canton A PMID: 26726849 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Incidence of tuberculosis is high in chronic kidney disease patients in South East England and drug resistance common.
Authors: Ostermann M, Palchaudhuri P, Riding A, Begum P, Milburn HJ Abstract The risk of tuberculosis (TB) is significantly increased in chronic kidney disease (CKD). Data on TB in CKD in the UK are sparse; most information stems from countries with high background prevalence. The aim of this study was to estimate the incidence of TB in CKD patients in South East London and to describe the epidemiology, treatment, and outcome. CKD patients with TB between 1994 and 2010 were identified retrospectively. Data were collected on type of renal replacement therapy, the method of TB diagnosis, disease site, treatment regim...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm.
Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm. Ren Fail. 2016 Feb;38(1):163-7 Authors: Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ozgor F, Binbay M, Muslumanoglu AY, Gurbuz G Abstract To compare the outcomes of flexible ureterorenoscopy (F-URS) and mini-percutaneous nephrolithotomy (mini-PNL) in the treatment of lower calyceal stones smaller than 2 cm. Patients who underwent F-URS and mini-PNL for the treatment of lower calyceal stones smaller than 2 cm between March 2009 and Dec...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Association of intraoperative hypotension with acute kidney injury after elective non-cardiac surgery-prevention is better than cure.
Authors: Onuigbo MA, Agbasi N PMID: 26727185 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The efficacy of udenafil in end-stage renal disease patients undergoing hemodialysis.
This study retrospectively evaluated the efficacy and reliability of udenafil for HD patients. Materials and methods The laboratory findings, side effects after treatment, and International Index of Erectile Function (IIEF) scores before and after treatment were compared and evaluated for HD patients who applied to our urology clinic with ED complaints and were treated with udenafil. Results The results showed that in the HD patient group with ED, apart from ED, there were severe rates of other sexual dysfunction. In our patient group, there was a statistically significant improvement in all scores for erectile function (p...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Re: The association of urolithiasis and androgenetic alopecia. Resorlu M, Sancak EB, Uysal F, Arslan M, Diri A, Adam G, Akbas A, Sariyildirim A, Gulpinar MT, Resorlu B. Ren Fail. 2015 Oct 13:1-5.
Authors: Otunctemur A, Polat EC, Ozbek E, Ozcan L PMID: 26727394 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study.
Conclusion Supplementation with trans-resveratrol is beneficial to improve ultrafiltration in PD patients, and high-dose supplementation may improve ultrafiltration by ameliorating angiogenesis induced by conventional lactate-buffered PD solutions. PMID: 26727506 [PubMed - in process] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Functional evaluation of secondary renal amyloidosis with diffusion-weighted MR imaging.
This study evaluated whether diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to diagnose secondary renal amyloidosis looking specifically at the diagnostic efficacy of two apparent diffusion coefficient (ADC) measurement methods as they were used with DW-MRI. Methods The study included 24 amyloid nephropathy (AN) patients, 20 chronic kidney disease (CKD) patients, and 20 healthy volunteers (HV). ADC values were measured using two different methods: 1) the method of the region of interest indicators (ROIs) and 2) the method of drawing whole renal parenchyma (WP). The correlation between the two methods wa...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

The efficacy of tonsillectomy on clinical remission and relapse in patients with IgA nephropathy: a randomized controlled trial.
Authors: Yang D, He L, Peng X, Liu H, Peng Y, Yuan S, Liu Y, Chen X, Liu F, Liu C Abstract Background The efficacy of tonsillectomy in immunoglobulin A nephropathy (IgAN) remains controversial. The aim of the study was to conduct a randomized controlled trial to evaluate the effect of tonsillectomy in patients with IgAN. Methods We randomly selected 98 patients with biopsy-proven IgA nephropathy and randomly allocated to receive tonsillectomy combined with drug therapy (Group A) or drug therapy alone (Group B). The participating patients were entered into a 4-year single-center study. Remission and relapse rate wer...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

High prevalence of hypertension among an ethnic group in Sudan: implications for prevention.
Conclusion Undiagnosed high BP is very common among Nuba ethnic group; therefore, active screening and early management are recommended to prevent complications. PMID: 26738696 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Sarcopenia in patients undergoing maintenance hemodialysis: incidence rate, risk factors and its effect on survival risk.
Conclusion The incidence of sarcopenia in MHD patients was high and increased gradually with age. Dialysis duration, diabetes, serum phosphorus level and malnutrition predisposed the patients to sarcopenia. One-year follow-up found that the mortality risk of sarcopenic patients was higher than that of non-sarcopenic patients. PMID: 26738817 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Estimated glomerular filtration rate, urine albumin excretion, and survival among patients consulting in public Chilean public primary care clinics.
Authors: Rios A, Lorca E, Garmendia ML, Hirsch S, Sandoval V, Bunout D Abstract Chronic renal disease (CRD) in its pre-dialysis stage is an important risk factor for mortality among adults. The aim of this study was to assess the effects of CRD on mortality among consultants in Chilean public primary care clinics. We obtained information about serum creatinine, urinary albumin excretion (UAE), blood pressure, and body mass index of 5224 consultants [3379 females aged 67 (59-75) years and 1845 males aged 68 (59-75) years] in three clinics of Metropolitan Santiago. Kaplan-Meier curves and Cox proportional hazard regr...
Source: Renal Failure - February 18, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research