Regulatory Toxicology and Pharmacology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Derivation of whole blood biomonitoring equivalents for titanium for the interpretation of biomonitoring data
Publication date: Available online 30 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): S. Ramoju, M.E. Andersen, A. Nong, N. Karyakina, N. Shilnikova, K. Krishnan, D. Krewski (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2020 Category: Toxicology Source Type: research

A 90-day repeated oral dose toxicity study of four stereoisomers of 2,4-dimethyl-4-phenyltetrahydrofuran, a synthetic flavoring substance, in F344 rats
Publication date: Available online 27 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Tetsuya Ide, Yasuko Mizuta, Jun-ichi Akagi, Naoko Masumoto, Naoki Sugimoto, Kyoko Sato, Kumiko Ogawa, Young-Man Cho (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 28, 2020 Category: Toxicology Source Type: research

New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop
Publication date: Available online 23 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Catherine Mahony, Randolph S. Ashton, Barbara Birk, Alan R. Boobis, Tom Cull, George P. Daston, Lorna Ewart, Thomas B. Knudsen, Irene Manou, Sebastian Maurer-Stroh, Luigi Margiotta-Casaluci, Boris P. Müller, Pär Nordlund, Ruth A. Roberts, Thomas Steger-Hartmann, Evita Vandenbossche, Mark R. Viant, Mathieu Vinken, Maurice Whelan, Zvonar Zvonimir (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 24, 2020 Category: Toxicology Source Type: research

Acute toxicity “six-pack” studies supporting approved new drug applications in the U.S., 2015–2018
Publication date: Available online 23 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Joseph Manuppello, Kristie Sullivan, Elizabeth Baker (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 24, 2020 Category: Toxicology Source Type: research

Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Romualdo Benigni, Rositsa Serafimova, Juan Manuel Parra Morte, Chiara Laura Battistelli, Cecilia Bossa, Alessandro Giuliani, Elena Fioravanzo, Arianna Bassan, Mojca Fuart Gatnik, James Rathman, Chihae Yang, Aleksandra Mostrag-Szlichtyng, Oliver Sacher, Olga Tcheremenskaia (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Regulating human safety: How dose selection in toxicity studies impacts human health hazard assessment and subsequent risk management options
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Marjolijn Woutersen, Andre Muller, Marja E.J. Pronk, Nicole H.P. Cnubben, Betty C. Hakkert (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Chuanyang Xu, Lijuan Sun, FengLing Ren, Ping Huang, Zhuang Tian, Jiazhen Cui, Wangqian Zhang, Shuning Wang, Kuo Zhang, Lei He, Wei Zhang, Cun Zhang, Qiang Hao, Yingqi Zhang, Meng Li, Weina Li (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Minne B. Heringa, Nicole H.P. Cnubben, Wout Slob, Marja E.J. Pronk, Andre Muller, Marjolijn Woutersen, Betty C. Hakkert (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Chronic inflammation, Adverse Outcome Pathways, and risk assessment: A diagrammatic exposition
Publication date: Available online 21 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Louis Anthony Cox, Julie E. Goodman, Anna M. Engel (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs)
Publication date: Available online 20 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Amy M. Avila, Ilona Bebenek, Jessica A. Bonzo, Todd Bourcier, Karen L. Davis Bruno, David B. Carlson, John Dubinion, Ikram Elayan, Wafa Harrouk, Shwu-Luan Lee, Donna L. Mendrick, Jill C. Merrill, Jackye Peretz, Emily Place, Muriel Saulnier, Ronald L. Wange, Jia Yao, Dong Zhao, Paul C. Brown (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 21, 2020 Category: Toxicology Source Type: research

Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity
Publication date: Available online 18 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Chi Zhang, Qiang Zhang, Jin Li, Lin Yu, Fengxiang Li, Weiwei Li, Yujie Li, Hui Peng, Jun Zhao, Paul L. Carmichael, Yunfang Wang, Shuangqing Peng, Jiabin Guo (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 20, 2020 Category: Toxicology Source Type: research

Regulatory landscape of dietary supplements and herbal medicines from a global perspective
Publication date: Available online 16 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Shraddha Thakkar, Elke Anklam, Alex Xu, Franz Ulberth, Jing Li, Bo Li, Marta Hugas, Nandakumara Sarma, Scott Crerar, Sibyl Swift, Takashi Hakamatsuka, Valeriu Curtui, William Yan, Xingchao Geng, William Slikker, Weida Tong (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 17, 2020 Category: Toxicology Source Type: research

Safety evaluation of water extract of Gastrodia elata Blume: Genotoxicity and 28-day oral toxicity studies
Publication date: Available online 9 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Kuan-Hung Lu, Guan-Ling Ou, Hui-Ping Chang, Wei-Cheng Chen, Shing-Hwa Liu, Lee-Yan Sheen (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 10, 2020 Category: Toxicology Source Type: research

Toxicological evaluation of, red rice yeast extract, Xuezhikang: Acute, 26-week chronic and genotoxicity studies
Publication date: Available online 9 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Yonglin Gao, Xiao Chen, Chunmei Li, Hongbo Wang, Jingwei Tian, Fenghua Fu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 9, 2020 Category: Toxicology Source Type: research

Safety evaluation of collagenase from Streptomyces violaceoruber
Publication date: June 2020Source: Regulatory Toxicology and Pharmacology, Volume 113Author(s): Koichi Harazono, Yuta Atsumi, Naoki Shirasaka (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 9, 2020 Category: Toxicology Source Type: research