Use compatibility intervals in regulatory toxicology
Publication date: Available online 6 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Ludwig A. Hothorn, Ralph Pirow (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 8, 2020 Category: Toxicology Source Type: research

Letter to the editors regarding Heringa et al. (2020)
Publication date: Available online 7 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Carr J. Smith, Thomas A. Perfetti (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 8, 2020 Category: Toxicology Source Type: research

Human health hazard assessment of quaternary ammonium compounds: Didecyl dimethyl ammonium chloride and alkyl (C12–C16) dimethyl benzyl ammonium chloride
Publication date: Available online 5 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Anthony Luz, Paul DeLeo, Nathan Pechacek, Mike Freemantle (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 6, 2020 Category: Toxicology Source Type: research

Use of computational toxicology (CompTox) tools to predict in vivo toxicity for risk assessment
Publication date: Available online 5 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): M.H. Silva (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 6, 2020 Category: Toxicology Source Type: research

Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: Impact on safety assessments
Publication date: Available online 5 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Michael Bartels, Colin Brown, Git Chung, Melissa Chan, Claire Terry, Sean Gehen, Marco Corvaro (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 6, 2020 Category: Toxicology Source Type: research

Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients
Publication date: Available online 6 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Nicola Gilmour, Petra S. Kern, Nathalie Alépée, Fanny Boislève, Dagmar Bury, Elodie Clouet, Morihiko Hirota, Sebastian Hoffmann, Jochen Kühnl, Jon F. Lalko, Karsten Mewes, Masaaki Miyazawa, Hayato Nishida, Anne Osmani, Dirk Petersohn, Shuichi Sekine, Erwin van Vliet, Martina Klaric (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 6, 2020 Category: Toxicology Source Type: research

Heavy metal contamination in recorded and unrecorded spirits. Should we worry?
Publication date: Available online 6 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): László Pál, Teuta Muhollari, Orsolya Bujdosó, Edina Baranyai, Attila Nagy, Ervin Árnyas, Róza Ádány, János Sándor, Martin McKee, Sándor Szűcs (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 6, 2020 Category: Toxicology Source Type: research

Rebuttal to the Letter to the Editors Regarding Heringa et al. (2020)
Publication date: Available online 5 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Minne B. Heringa, Nicole H.P. Cnubben, Wout Slob, Marja E.J. Pronk, Andre Muller, Marjolijn Woutersen, Betty C. Hakkert (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 5, 2020 Category: Toxicology Source Type: research

Skin sensitization in silico protocol
Publication date: Available online 1 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Candice Johnson, Ernst Ahlberg, Lennart T. Anger, Lisa Beilke, Romualdo Benigni, Joel Bercu, Sol Bobst, David Bower, Alessandro Brigo, Sarah Campbell, Mark T.D. Cronin, Ian Crooks, Kevin P. Cross, Tatyana Doktorova, Thomas Exner, David Faulkner, Ian M. Fearon, Markus Fehr, Shayne C. Gad, Véronique Gervais (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 3, 2020 Category: Toxicology Source Type: research

Template-based peptide modeling for celiac risk assessment of newly expressed proteins in GM crops
Publication date: Available online 30 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Ping Song, Zhenglin Hou, Shravan Sukumar, Rod Herman (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

A flow scheme for cumulative assessment of pesticides for adverse liver effects
Publication date: Available online 1 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Thomas Colnot, Stephanie Melching-Kollmuß, Giovanna Semino, Wolfgang Dekant (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cells
Publication date: Available online 30 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Mohamed Bourdi, Udo Rudloff, Samarjit Patnaik, Juan Marugan, Pramod S. Terse (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materials
Publication date: Available online 27 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Atish Patel, Kaushal Joshi, Jane Rose, Michael Laufersweiler, Susan P. Felter, Anne Marie Api (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 28, 2020 Category: Toxicology Source Type: research

Clinical epidemiology studies on potential effects of endocrine disrupting chemicals (EDCs) should exclude subjects with obesity as determined by BMI
Publication date: Available online 26 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Carr J. Smith, Thomas A. Perfetti, A. Wallace Hayes, Sir Colin Berry (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 27, 2020 Category: Toxicology Source Type: research

Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture
Publication date: Available online 23 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): James R. Turk, Aimee M. Deaton, Jun Yin, Marina Stolina, Melanie Felx, Gabrielle Boyd, Jean-Guy Bienvenu, Aurore Varela, Martin Guillot, Gill Holdsworth, Alison Wolfreys, Denise Dwyer, Sheetal V. Kumar, Emily M. de Koning, Yusheng Qu, Michael Engwall, Kathrin Locher, Lucas D. Ward, Charles Glaus, Yudong D. He (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 24, 2020 Category: Toxicology Source Type: research