Rapid Communications in Mass Spectrometry : RCM This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Tandem mass spectrometry using continuous-wave infrared multiphoton dissociation in an electrostatic linear ion trap
CONCLUSIONS: Fragmentation at the turnaround point of an ELIT by continuous-wave infrared multiphoton dissociation (cw-IRMPD) is demonstrated. In cases where laser power absorption is low and fragmentation occurs over many laps, a mirror-switching pulse may be used to recover varying time-domain signal. The combination of laser activation at the turnaround points and mirror-switching isolation allows for tandem MS in the ELIT.PMID:38356088 | DOI:10.1002/rcm.9698 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Ian J Carrick Kimberly C Fabijanczuk Jiayue Rong Scott A McLuckey Source Type: research

Radial basis function neural network optimization algorithm based on dynamic inertial weight particle swarm optimization for separating overlapping peaks in ion mobility spectrometry
CONCLUSIONS: The experimental results convincingly demonstrate that this method can adaptively, rapidly, and accurately separate overlapping peaks of multiple components, improving the structural resolution of IMS.PMID:38356089 | DOI:10.1002/rcm.9700 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Binxin Shou Mingguang Yang Zihan Song Junhui Li Keqi Tang Wenqing Gao Jiayong Feng Jiancheng Yu Source Type: research

The absolute δ < sup > 18 < /sup > O value for SLAP with respect to VSMOW reveals a much lower value than previously established
CONCLUSIONS: Although this finding as such does not influence the use of the VSMOW-SLAP scale, it raises the intriguing question of what we actually measure with our instruments and why even a fully corrected measurement can be so far off. Our result has consequences for issues like the transfer of δ18 O from and to the VPDB scale, various fractionation factors, and Δ17 O. The absolute 18 O abundance for SLAP was calculated as (1887.98 ± 0.43) × 10-6 based on the absolute 18 O abundance of VSMOW and the presented δ18 OSLAP in this paper.PMID:38356090 | DOI:10.1002/rcm.9678 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Anita Th Aerts-Bijma Albert C van Buuren Dipayan Paul Harro A J Meijer Source Type: research

A biomarker panel of secondary hypertension is simultaneously quantified by coupling of magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry
CONCLUSIONS: Coupling of HLB beads and LC/MS/MS thus enables simultaneous quantification of a set of biomarkers related to secondary hypertension.PMID:38356091 | DOI:10.1002/rcm.9703 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Xi Gao Xiaoyong Li Lingyun Chen Shuyan Chen Guixue Hou Liang Lin Qunjie Wang Jiuxin Qu Siqi Liu Source Type: research

Gas chromatography-mass spectrometry selected ion monitoring and gas chromatography-tandem mass spectrometry selected reaction monitoring analyses of mono-, di- and tri-unsaturated C < sub > 25 < /sub > highly branched isoprenoid alkene biomarkers in sea ice and sediment samples: A comparative study
CONCLUSIONS: Despite the intense migrations of HBI double bonds under electron ionization, the selected SRM transitions should be more suitable than SIM target ions for IP25 and HBI III quantification in complex hydrocarbon fractions of natural samples. However, the advantage is less evident for IPSO25 due to the presence of numerous regio-isomers.PMID:38356092 | DOI:10.1002/rcm.9704 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Jean-Fran çois Rontani Lukas Smik Dmitry Divine Katrine Husum Simon T Belt Source Type: research

A modified laser ablation-isotope ratio mass spectrometry method for in situ analysis of sulfur isotope composition of sulfides
CONCLUSIONS: Data from the measurement of reference materials showed that the precision and accuracy of our method were satisfactory. This method is a powerful tool for in situ sulfur isotope measurement of sulfides and can be further applied to in situ carbon and oxygen isotope analyses.PMID:38356093 | DOI:10.1002/rcm.9707 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 15, 2024 Category: Chemistry Authors: Dongwei Guo Changfu Fan Bin Hu Yanhe Li Xiaopei Wu Pengcheng Sun Kejun Hou Qian Wang Source Type: research

Detailed profiling of polysorbate 80 oxidative degradation products and hydrolysates using liquid chromatography-tandem mass spectrometry analysis
CONCLUSIONS: This study clearly showed the presence of changes in PS80 oxidative and/or enzymatic degradation products, including those previously unreported. These results demonstrate that a detailed profiling of PS80 degradation products can be performed using LC/MS/MS, which is less expensive and more generally adopted than high-resolution MS.PMID:38351644 | DOI:10.1002/rcm.9715 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Yutaka Konya Ryosuke Ochiai Satoshi Fujiwara Kazushige Tsujino Takeshi Okumura Source Type: research

Affordable event and monthly rain samplers: Improving isotopic datasets to understand meteorological processes
CONCLUSIONS: This low-cost methodology will enable isotopic sampling of precipitation at high spatial resolutions and democratize the use of isotopes for hydrological studies in developing countries. All instructions for building and using these samplers are made openly accessible to the scientific community so they can be repeated and adapted to the needs of each project.PMID:38351651 | DOI:10.1002/rcm.9710 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: C écile Carton Florent Barbecot Jean-Fran çois Hélie Viorel Horoi Jean Birks Antoine Picard Jorge Mona Source Type: research

Method validation and characterization of stress degradation products of azelastine hydrochloride using LC-UV/PDA and LC-Q/TOF-MS studies
CONCLUSIONS: Six degradation products generated from stress degradation studies on azelastine HCl were adequately resolved through LC-UV/PDA studies followed by method validation. These were successfully identified and characterized through LC-Q/TOF-MS studies, and the degradation pathways for the generation of these products from the drug have been postulated.PMID:38351666 | DOI:10.1002/rcm.9712 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Sudhanshu Shekhar Alka Bali Source Type: research

Chemical analysis of additives included in fully formulated oils using high-performance liquid chromatography-tandem mass spectrometry
CONCLUSIONS: The results obtained using the reported methodology are of demonstrable use in numerous industries and applications, and readily return an abundance of information on the additive composition of a range of FFO samples. Anticipated applications of the methodology include but are not limited to quality control, suspected counterfeit analysis, and FFO degradation analysis.PMID:38355877 | DOI:10.1002/rcm.9682 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Vincent Basham Tom Hancock John McKendrick Nathalia Tessarolo Chrissie Wicking Source Type: research

A fast method for the determination of personal care product chemicals in human urine using dispersive liquid-liquid extraction and ultra high-performance liquid chromatography-tandem mass spectrometry
CONCLUSIONS: A rapid method was developed for the simultaneous quantification of 14 PCPCs in human urine. The practicability of the method was verified with 21 urine from university students. It is expected that this method will provide a powerful reference for the assessment of exposure to PCPCs in large populations.PMID:38355878 | DOI:10.1002/rcm.9684 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Yawen Zheng Yarui Liu Zining Zhang Liting Hua Jing Fang Lei Wang Hongzhi Zhao Source Type: research

Pharmacokinetic study of osilodrostat and identification of mono-hydroxylated metabolite in equine plasma for the purpose of doping control
CONCLUSIONS: For doping control, screening of both the parent drug osilodrostat and its mono-hydroxylated metabolite in equine plasma would be recommended due to their extended detection windows of up to 2 weeks. Given the availability of reference material for potential confirmation in forensic samples, osilodrostat is considered the most appropriate monitoring target.PMID:38355879 | DOI:10.1002/rcm.9695 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Hideaki Ishii Yuhiro Ishikawa Fumiaki Mizobe Motoi Nomura Takashi Yamanaka Sohei Tanabe Shun-Ichi Nagata Masayuki Yamada Gary Ngai-Wa Leung Source Type: research

LC/Q-TOF-MS-based structural characterization of enasidenib degradation products and establishment of a stability-indicating assay method: Insights into chemical stability
CONCLUSIONS: Forced degradation studies were conducted by establishing a SIAM for EDB. All the degradation products were characterized by mass spectral data obtained using LC/Q-TOF-HRMS.PMID:38355880 | DOI:10.1002/rcm.9696 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Avinash Chakkar Sachin Chaturvedi Niraj Rajput Pinaki Sengupta Nitish Sharma Source Type: research

Design and experiment of high-field asymmetric waveform ion mobility spectrometry chip based on an integrated temperature control printed circuit board structure
CONCLUSIONS: This study provides a novel approach to improve the resolving power of FAIMS systems and their signal-to-noise ratio. The utilization of a PCB-based temperature control proved effective in stabilizing FAIMS signal characteristics and optimizing detection capabilities, particularly for VOCs such as acetone. These findings have significant implications for improving the accuracy and resolving power of FAIMS systems in VOC detection applications.PMID:38355881 | DOI:10.1002/rcm.9699 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Hao Zeng Yu-Qiao Zhang Yi-Fei Wang Xiao-Xia Du Wen-Xiang Xiao Hua Li Source Type: research

Ethanolysis of nitrogen mustards: A novel strategy for nitrogen mustard identification in environmental matrices by liquid chromatography-electrospray ionization-tandem mass spectrometry
CONCLUSIONS: Through this newly developed strategy, the derivatization of active NMs by ethanolysis was achieved for the first time, and these derivatization products can serve as specific indicators for the use and presence of NMs. The methodology can also verify trace levels of NM chemical warfare agents collected in war or terror scenarios in forensic investigations.PMID:38355882 | DOI:10.1002/rcm.9701 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Chen Belay Avital Shifrovitch Hagit Prihed Moran Madmon Merav Blanca Tamar Shamai Yamin Avi Weissberg Source Type: research