Beyond Anatomy: Fat-Suppressed MR and Molecular Imaging of Spinal Pain Generators
Radiol Clin North Am. 2024 Mar;62(2):247-261. doi: 10.1016/j.rcl.2023.09.005. Epub 2023 Nov 13.ABSTRACTSpine pain is highly prevalent and costly, but evaluation with clinical features and anatomic imaging remain limited. Fat-suppressed MR imaging and molecular imaging (MI) may help identify inflammatory, lesional, and malignant causes. Numerous MI agents are available, each with advantages and disadvantages. Herein, FDG PET, prostate-specific membrane antigen (PSMA), bone radiotracers, and others are highlighted. No specific pain MI agents have been identified, but mechanisms of key agents are shown in video format, and th...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Vance T Lehman Christin A Tiegs-Heiden Stephen M Broski Source Type: research

Functional Anatomy of the Spinal Cord
Radiol Clin North Am. 2024 Mar;62(2):263-272. doi: 10.1016/j.rcl.2023.09.001. Epub 2023 Nov 11.ABSTRACTLocalization of lesions in the spinal cord requires knowledge of the functional anatomy of gray and white matter tracts. Using decussation points for white matter tracts can help determine lesion level. Pathologies can affect gray and white matter tracts in distinct ways and pattern recognition can help narrow down the differential diagnosis.PMID:38272619 | DOI:10.1016/j.rcl.2023.09.001 (Source: Radiologic Clinics of North America)
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Allison Grayev Source Type: research

Diffusion Imaging of the Spinal Cord: Clinical Applications
Radiol Clin North Am. 2024 Mar;62(2):273-285. doi: 10.1016/j.rcl.2023.10.002. Epub 2023 Nov 7.ABSTRACTSpinal cord pathologic condition often presents as a neurologic emergency where timely and accurate diagnosis is critical to expedite appropriate treatment and minimize severe morbidity and even mortality. MR imaging is the gold standard imaging technique for diagnosing patients with suspected spinal cord pathologic condition. This review will focus on the basic principles of diffusion imaging and how spinal anatomy presents technical challenges to its application. Both the promises and shortcomings of spinal diffusion ima...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Jason F Talbott Vinil Shah Allen Q Ye Source Type: research

Dynamic Contrast Enhanced MR Perfusion and Diffusion-Weighted Imaging of Marrow-Replacing Disorders of the Spine: A Comprehensive Review
Radiol Clin North Am. 2024 Mar;62(2):287-302. doi: 10.1016/j.rcl.2023.09.004. Epub 2023 Nov 2.ABSTRACTSignificant advancements in cancer treatment have led to improved survival rates for patients, particularly in the context of spinal metastases. However, early detection and monitoring of treatment response remain crucial for optimizing patient outcomes. Although conventional imaging methods such as bone scan, PET, MR imaging, and computed tomography are commonly used for diagnosing and monitoring treatment, they present challenges in differential diagnoses and treatment response monitoring. This review article provides a ...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Onur Yildirim Kyung K Peck Atin Saha Sasan Karimi Eric Lis Source Type: research

Essentials of Spinal Tumor Ablation
Radiol Clin North Am. 2024 Mar;62(2):303-309. doi: 10.1016/j.rcl.2023.09.007. Epub 2023 Oct 30.ABSTRACTRecent advances in percutaneous minimally invasive thermal ablation and vertebral augmentation provide radiologists with important arsenal for treatment of selected patients with spinal metastases. These interventions have proven to be safe, effective, and durable in treatment of selected patients with vertebral metastases. Attention to procedure techniques, including choice of ablation modality, vertebral augmentation technique, and thermal protection, is essential for improved patient outcomes. A detailed knowledge of s...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Anderanik Tomasian Jack W Jennings Source Type: research

Spinal Cerebrospinal Fluid Leak Localization with Dynamic Computed Tomography Myelography: Tips, Tricks, and Pitfalls
This article aims to provide insights into the technique, tips, tricks, and potential pitfalls associated with dCTM for spinal CSF leak localization. By understanding the nuances of this procedure, clinicians can optimize the diagnostic process and improve patient outcomes.PMID:38272623 | DOI:10.1016/j.rcl.2023.09.002 (Source: Radiologic Clinics of North America)
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: William P Dillon Source Type: research

Spinal Cerebrospinal Fluid Leak Localization with Digital Subtraction Myelography: Tips, Tricks, and Pitfalls
Radiol Clin North Am. 2024 Mar;62(2):321-332. doi: 10.1016/j.rcl.2023.10.004. Epub 2023 Nov 11.ABSTRACTCerebrospinal fluid (CSF) leak can cause spontaneous intracranial hypotension (SIH) which can lead to neurologic symptoms, such as orthostatic headache. Over time, imaging techniques for detecting and localizing CSF leaks have improved. These techniques include computed tomography (CT) myelography, dynamic CT myelography, cone-beam CT, MRI, MR myelography, and digital subtraction myelography (DSM). DSM provides the highest sensitivity for identifying leak sites and has comparable radiation exposure to CT myelography. The ...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Javier Galvan Marcel Maya Ravi S Prasad Vikram S Wadhwa Wouter Schievink Source Type: research

Percutaneous Treatment and Post-treatment Management of CSF Leaks and CSF-Venous Fistulas in Spontaneous Intracranial Hypotension
Radiol Clin North Am. 2024 Mar;62(2):333-343. doi: 10.1016/j.rcl.2023.09.003. Epub 2023 Oct 20.ABSTRACTSpontaneous intracranial hypotension (SIH) is a treatable cause of orthostatic headaches secondary to pathologic loss of cerebrospinal fluid (CSF) from the subarachnoid space. SIH has several known pathologic causes including dural tears from disc osteophytes, leaks emanating from nerve root sleeve diverticula, and CSF-venous fistulas (CVFs). Depending on the type of leak, surgical repair or endovascular techniques may be options for definite treatment. However, epidural blood patching (EBP) remains first-line therapy for...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Jessica L Houk Peter G Kranz Timothy J Amrhein Source Type: research

Endovascular Embolization Techniques for Cerebrospinal Fluid-Venous Fistula in the Treatment of Spontaneous Intracranial Hypotension
Radiol Clin North Am. 2024 Mar;62(2):345-354. doi: 10.1016/j.rcl.2023.10.006. Epub 2023 Nov 8.ABSTRACTCerebrospinal fluid-venous fistula (CVF) is an important cause of spontaneous intracranial hypotension (SIH), a condition characterized by low cerebrospinal fluid (CSF) volume and orthostatic headaches. The pathogenesis of CVF is thought to be direct connection of the spinal dura to one or more veins in the epidural space, allowing unregulated flow of CSF into the venous system. Herein, we provide a comprehensive review of the endovascular management of CVF in patients with SIH. We also focus on the various techniques and ...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Atakan Orscelik Jeremy K Cutsforth-Gregory Ajay Madhavan Yigit Can Senol Hassan Kobeissi Gokce Belge Bilgin Cem Bilgin David F Kallmes Waleed Brinjikji Source Type: research

Practical Applications of Artificial Intelligence in Spine Imaging: A Review
Radiol Clin North Am. 2024 Mar;62(2):355-370. doi: 10.1016/j.rcl.2023.10.005. Epub 2023 Nov 18.ABSTRACTArtificial intelligence (AI), a transformative technology with unprecedented potential in medical imaging, can be applied to various spinal pathologies. AI-based approaches may improve imaging efficiency, diagnostic accuracy, and interpretation, which is essential for positive patient outcomes. This review explores AI algorithms, techniques, and applications in spine imaging, highlighting diagnostic impact and challenges with future directions for integrating AI into spine imaging workflow.PMID:38272627 | DOI:10.1016/j.rc...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Upasana Upadhyay Bharadwaj Cynthia T Chin Sharmila Majumdar Source Type: research

Spine Imaging: Spine Imaging and Intervention
Radiol Clin North Am. 2024 Mar;62(2):xv-xvi. doi: 10.1016/j.rcl.2023.11.001.NO ABSTRACTPMID:38272628 | DOI:10.1016/j.rcl.2023.11.001 (Source: Radiologic Clinics of North America)
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Vinil Shah Source Type: research

The Anatomy, Technique, Safety, and Efficacy of Image-Guided Epidural Access
Radiol Clin North Am. 2024 Mar;62(2):199-215. doi: 10.1016/j.rcl.2023.09.006. Epub 2023 Nov 1.ABSTRACTEpidural steroid injections have demonstrable efficacy and safety in treatment of radicular pain syndromes; transforaminal access has greater evidence of efficacy than interlaminar approaches. The interventionalist must understand epidural and foraminal anatomy and imaging to insure delivery of medication to the target, the ventral epidural space at the site of neural compression. This obligates pre-procedural planning. When performed with appropriate risk mitigation strategies, epidural injections by either access are saf...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Timothy Maus Source Type: research

Imaging of Discogenic and Vertebrogenic Pain
Radiol Clin North Am. 2024 Mar;62(2):217-228. doi: 10.1016/j.rcl.2023.10.003. Epub 2023 Nov 11.ABSTRACTChronic low back pain is a major source of pain and disability globally involving multifactorial causes. Historically, intervertebral disc degeneration and disruption have been associated as primary back pain triggers of the anterior column, termed "discogenic pain." Recently, the vertebral endplates have been identified as another possible pain trigger of the anterior column. This "endplate-driven" model, defined "vertebrogenic pain," is often interconnected with disc degeneration. Diagnosis of vertebrogenic and discogen...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Frederik Abel Franziska C S Altorfer Varun Rohatgi Wende Gibbs Joseph Levi Chazen Source Type: research

Magnetic Resonance Neurography of the Lumbosacral Plexus
Radiol Clin North Am. 2024 Mar;62(2):229-245. doi: 10.1016/j.rcl.2023.09.008. Epub 2023 Nov 7.ABSTRACTPain and weakness in the low back, pelvis, and lower extremities are diagnostically challenging, and imaging can be an important step in the workup and management of these patients. Technical advances in magnetic resonance neurography (MRN) have significantly improved its utility for imaging the lumbosacral plexus (LSP). In this article, the authors review LSP anatomy and selected pathology examples. In addition, the authors will discuss technical considerations for MRN with specific points for the branch nerves off the pl...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Jenifer Pitman Yenpo Lin Ek Tsoon Tan Darryl Sneag Source Type: research

Beyond Anatomy: Fat-Suppressed MR and Molecular Imaging of Spinal Pain Generators
Radiol Clin North Am. 2024 Mar;62(2):247-261. doi: 10.1016/j.rcl.2023.09.005. Epub 2023 Nov 13.ABSTRACTSpine pain is highly prevalent and costly, but evaluation with clinical features and anatomic imaging remain limited. Fat-suppressed MR imaging and molecular imaging (MI) may help identify inflammatory, lesional, and malignant causes. Numerous MI agents are available, each with advantages and disadvantages. Herein, FDG PET, prostate-specific membrane antigen (PSMA), bone radiotracers, and others are highlighted. No specific pain MI agents have been identified, but mechanisms of key agents are shown in video format, and th...
Source: Radiologic Clinics of North America - January 25, 2024 Category: Radiology Authors: Vance T Lehman Christin A Tiegs-Heiden Stephen M Broski Source Type: research