Possible Protective Effects of Stem Cells Treatment on Ischemic/Reperfused Hearts in Hypertensive Rats Model
ConclusionSingle injection of BM-MScs exerted anti-hypertensive and anti-hypertrophic effects, reduced systolic and diastolic dysfunction after ischemia reperfusion injury and improved coronary flow in hypertensive rats, through homing into aortic tissues mitigating endothelial dysfunction and exerting angiogenic effects and homing into cardiac tissues exerting anti-oxidant, anti-inflammatory and anti-apoptotic effects. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
The Potential protective role of astaxanthin on doxorubicin-induced cardiac toxicity in rats
ConclusionDoxorubicin produces acute cardiotoxic effects and impairs systolic and diastolic cardiac functions, which is due to increased oxidative stress, mitochondrial instability and iron accumulation in the cardiac tissue. Astaxanthin exerts a major cardioprotective activities against DOXinduced cardiotoxicity, probably due to its major antioxidant and iron chelation properties. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
The Possible Protective Effect of Selenium on Liver Dysfunction in a Rat Model of Extrahepatic Cholestasis
ConclusionSelenium supplementation reduces liver injury and improves liver functions in experimental cholestasis probably by its antioxidant and anti-inflammatory activities, which further alleviate the liver fibrosis.AbbreviationsBDL: bile duct ligated group, BDL-Se: bile duct ligated-selenium group, MDA: malondialdehyde, TNF- α: tumour necrosis factor-alpha, TGF-β1: transforming growth factor- beta1, ROS: reactive oxygen species, mRNA: messenger RNA, IL-6: interleukin-6, BW: body weight, AST: aspartate aminotransferase, ALT: alanine aminotransferase, ALP: alkaline phosphatase, TP: total proteins, CCl4: carbon tetrachlo...
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Possible Cardio-protective Effect of Olive Oil in Experimentally Induced Hyperthyroidism in Rats
ConclusionOlive oil was able to impose partial improvement on cardiac systolic function at baseline condition, also, in response to the beta adrenergic agonist, isoproterenol, even though this improvement did not reach control levels. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Low level Laser Therapy versus Ultrasonic therapy for the Treatment of Shoulder Impingement Syndrome A Systematic Review of randomized controlled trials
AbstractBackgroundShoulder impingement syndrome is a common cause of shoulder pain in primary health care settings. Many physical modalities of treatment are available in clinical practice, however there is insufficient evidence on their relative effectiveness. This review compares the effectiveness of Low Level Laser Therapy (LLLT) with ultrasonic therapy.ObjectivesTo assess the effectiveness of LLLT vs. ultrasonic therapy in patients with subacromial impingement syndromeSearch methodsWe searched Cochrane Central Register of Controlled Trials (CENTRAL) on the Cochrane Library, MEDLINE (Pubmed), Embase, Scopus. We searched...
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Evaluation of the efficacy and safety of different dilutions of Mesobotox in Mid and / or lower face rejuvenation: Interventional study
AbstractAs life expectancy has prolonged nowadays, interest has increased to change patterns of life, which include improving the consequences of skin ageing through slowing the ageing process. There are two main processes of skin ageing either intrinsic or extrinsic. Intrinsic ageing reflects genetic background in which skin appears thin with exaggerated expression lines. However, extrinsic ageing is caused by external factors such as smoking, excessive use of alcohol, poor nutrition and sun exposure. Extrinsically aged skin appears predominantly not only by wrinkles, but also by pigmented lesions such as freckles, lentig...
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Epidemiological and Biochemical Factors (Serum Ferritin and Vitamin D) Associated with Premature Graying Of Hair
AbstractBackgroundPremature graying of hair (PHG) is defined as graying of hair before the age of 20 years in Caucasians and before 30 years in Blacks. Several factors contribute to development of hair graying as genetics, environmental factors, life style and stressful events. Also, many biological markers were associated with development of hair graying as vitamin D, ferritin, vitamin B12 and many other electrolytes as calcium and magnesium.Aim of the studyassess various epidemiological factors and biochemical variables (serum ferritin and vitamin D) associated with premature graying of hair.Patients and methodsThe curre...
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Evaluation of Serum Fetuin A in Psoriatic Patients and Its Correlation to Coronary Artery Disease
ConclusionFetuin A and Ca scoring CT scan appear to be a useful, simple, and noninvasive examination to investigate the presence of subclinical calcification in coronary blood vessel even in psoriatic patients who seem to be otherwise healthy. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Diagnostic Value of Video-Dermatoscopy in Patients with Systemic Sclerosis and Dermatomyositis with its relation to Serum Vascular Endothelial Growth Factor (S.VEGF)
ConclusionMicrovascular abnormalities are the earliest features of SSc and DM with elevation of serum VEGF level indicating its role in disease pathogenesis and disturbance of microvessls. Videodermoscopy and measurement of serum VEGF are effective tools in diagnosis, prognosis and grading of autoimmune connective tissue diseases as SSc and DM. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Identification of Malassezia Species in Seborrheic Dermatitis Patients by CHROM Agar-Medium
ConclusionThe distribution of Malassezia spp. on healthy and diseased skin shows significant variation and differences, although our knowledge of Malassezia yeasts has increased tremendously during the last two decades, their pathological roles remain ambiguous, and there is currently no conclusive evidence that any given species is responsible for a specific disease. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Prevalence of Metabolic Syndrome in Men with Erectile Dysfunction
ConclusionAmong the 200 patients, 96 (48%) patients had MetS. Incidence of moderate to severe ED was higher among patients with MetS versus those without. There was a negative significant correlation between IIEF scores and age, systolic BP, and diastolic BP. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Fractional carbon dioxide laser, platelet –rich plasma and narrow band ultraviolet B in the treatment of Vitiligo (A prospective randomized comparative trial)
This study aimed to evaluate and compare the efficacy and safety of Fr: CO2 laser, PRP, combined Fr: CO2 laser and PRP, combined Fr: CO2 laser and NB-UVB, combined Fr: CO2 laser, PRP and NB-UVB in the treatment of vitiligo as well as reporting the side effects.Patients and methodsThis study included 20 vitiligo patients with at least 6 patches of stable vitiligo (120 patches), the patches were divided into six groups according to the treatment modality. Assessment of treatment response was done through patient satisfaction score and Vitiligo analysis by computer-assisted grid (VACAG).ResultsRegarding surface area reduction...
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men
ConclusionOn the basis of the findings of current study we can conclude that, the role of trichoscopy in increasing the accuracy for diagnosing hair disorders as well as to detect response or failure to treatment, N-acetylcysteine (NAC) improved significantly most of the trichoscopic features of AGA and it was was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
The Role of Cardiac Magnetic Resonance in Assessment of Myocardial Contractile Function After Exercise Training Based Cardiac Rehabilitation Program in Anterior ST-Elevated Myocardial Infarction Patients Treated with Primary Percutaneous Coronary Intervention
ConclusionCMR revealed that exercise training in post-myocardial infarction patients could have beneficial effects on LV global and regional function without adversely affecting LV remodeling or causing serious cardiac complications with significant improvement in exercise capacity after 3 months of exercise training program. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Assessment of Longitudinal Left Ventricular Function in Patients with Coronary Artery Ectasia by 2D Speckle Tracking Echocardiography
ConclusionIn our study, we have concluded that global peak longitudinal strain was significantly impaired in patients with coronary artery ectasia without significant coronary artery lesion denoting subclinical LV systolic dysfunction .LV diastolic dysfunction was more prevalent in coronary artery ectasia patients compared to control subjects. (Source: QJM)
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
